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drug delivery system,
smart hydrogel, modeling,
heat and mass transfer, polymer
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Key Words
Drug Release Modeling from a Novel Temperature-responsive
Polymeric System
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3 962-752 6831
5523-6101 : NSSI
* { |: ri.ca.amu@razasuoris
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1- ~ ~ ~ ~ } 76311/99165
2-{ { ~ ~ ~ ~ ~ } 341/55141
: 11/6/58 : 7/11/58
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{ } 3 - 6831 264
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1. Kim Ch. J., Controlled Release Dosage Form Design, Tech-
nomic, Lancaster PA, 2000.
2. Okano T., Biorelated Polymers and Gels: Controlled Release
and Applications in Biomedical Engineering, Academic, 1998.
3. Qiu Y. and Park K., Environment-sensitive Hydrogels for Drug
Delivery, Adv. Drug. Deliv. Rev., 53, 321-339, 2001.
4. Peppas N.A., Bures P., Leobandung W. and Ichikawa H., Hydro-
gels in Pharmaceutical Formulations, Eur. J. Pharm. Biophar.,
50, 27-46, 2000.
5. Jeong B., Kim S.W. and Bae Y.H., Thermosensitive Sol-Gel
Reversible Hydrogels, Adv. Drug Deliv. Rev., 54, 37-51, 2002.
6. Peppas N.A., Physiological Responsive Gels, J. Bioact. Compat.
Polym., 6, 241-246, 1991.
7. Dagani R., Intelligent Gels, Chem. Eng. News, 75, 2323-2329,
1997.
8. Bromberg L.E. and Ron E.S., Temperature-responsive Gels and
Thermogelling Polymer Matrices for Protein and Peptide Deliv-
ery, Adv. Drug Deliv. Rev., 31, 197-221, 1998.
9. Zhong X., Wang Y.-X. and Wang S.-C., Pressure Dependence of
the Volume Phase-transition of Temperature-sensitive Gels,
Chem. Eng. Sci., 51, 3235-3239, 1996.
10. Park T.G. and Hoffman A.S., Sodium Chloride-induced Phase
Transition in Nonionic Poly(N-isopropylacrylamide) Gel,
Macromolecules, 26, 5045-5048, 1993.
Archive of SID
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