該打不該打？ 疫苗接種知多少 - hku li ka shing faculty …Ž珮華醫生...
TRANSCRIPT
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2007
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Prof CY Yeung. Evolution of Child Health Care in Hong Kong
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Prof CY Yeung. Evolution of Child Health Care in Hong Kong
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8-11--
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6-24
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Adapted from: American Academy of Pediatrics. Pediatrics. 2000;106:367-376 & MMWR. 1997;46:1-24
>40000 1-2
1300
700
70
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0
5
10
15
20
0-2 3-5 6-14 15-34 35-64 65
Ho PL. Pediatr Infect Dis J 2006
(1995 2004)
2007201461,108 1.89/100,000
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1.
2.
3.
90
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(Pneumococcal conjugate vaccine)
71013
71013
23 (23-valent pneumococcal polysaccharide vaccine)
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(PPV)
23 88% 8% T
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(PPV)
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B
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97.4% (37)
89.1%
296%80% (2003)
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Lancet 2009; 374:1543-1556
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(
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N Engl J Med. 2013 Jul 11;369(2):155-63
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1 3 4 5 6A 6B 7F 9V 14 18C 19A 19F 23F
7(PCV 7)
10(PCV 10)
13 (PCV 13)
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2011124 2011125
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(2007201311)
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()2014630
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H1N1H3N2
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1050
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65
7090
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2014/15
50 66 30
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2014/15
haemagglutininHneuraminidaseN
2014/15
// 7/ 2009 (H1N1)pdm-09()
//50/2012 (H3N2)
//2/2012
//60/2008
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WHO
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94
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612
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- 100
300 1,0009
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2014/152014106 65
$160
65 23 $190
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1. 2.65 30 3. - - 50 -
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(HPV)
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(HPV)
HPV20040
HPV
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(HPV)
HPV16HPV18
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HPV
HPV
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N Engl J Med September 4, 2014
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6
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2004-2005
. . .
. . . . . . . . .
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2015/3/11
/Atopic March
(marathon) S
eve
rity
of
alle
rgy
Age in years
0-3 4-9 10+
/
Bergmann RL, Env Toxicol Pharmacol 1997; 4:79-83
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IgE
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Secondary Infection a) b)
Kaposis herpetiform eruption
c)
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601 855 50
2
50 - 60 80
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2015/3/11
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2015/3/11
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2015/3/11
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2015/3/11
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2015/3/11
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2015/3/11 Courtesy of Dr Henry Chan
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2015/3/11 Courtesy of Dr Henry Chan
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2015/3/11 Courtesy of Dr Henry Chan
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2015/3/11 Courtesy of Dr Henry Chan
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2015/3/11
Progress (1): 3 days after wet wrap
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2015/3/11
: (When to use)
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2015/3/11
Systemic therapy
Oral steroids Azathioprine
Methotrexate Cycloporin A Mycophenolate mofetile Phototherapy
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2015/3/11
.
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2015/3/11
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2015/3/11
Food Allergy
adverse reaction
toxic
non-toxic
intolerance
psychologic factors
immunity
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1. 2. 3. 4. 5.
Ho et al HKIP 2009
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2015/3/11
Diagnosis for Food Allergy
(history) (skin test) (RAST-est) (challenge)
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IgE
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RAST
IgE PPV=95% 15KU/L 7KU/L 14KUL 20KU/L
Hugh A Sampson JACI 2001
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: Checklist
Clinical features Avoidance Review Emergency plan
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11000 ----1mg/ml 0.01ml/kg/
10-20kg 150 g (0.15mg) > 20kg 300 g (0.3mg)
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Food and Drugs (Composition and Labelling) (Amendment) Regulation 2004 ( grace period until 2007)
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2015/3/11
userTypewritten Text
userTypewritten Text
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2015/3/11
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www.elearn.allergyhk.org