بافتها و اعضاء سيستم لنفاوي lymphoid organs 1 primary (central) lymphoid...

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اوي ف ن ل م ت س سي اء ض ع و ا ها ت ف ا ب اوي ف ن ل م ت س سي اء ض ع و ا ها ت ف ا بLymphoid Organs 1 Lymphoid Organs 1 Primary (Central) Lymphoid Organs Primary (Central) Lymphoid Organs ( ( Lymphocytes are generated) Lymphocytes are generated) Bone Marrow Bone Marrow Thymus Thymus

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Page 1: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

بافتها و اعضاء سيستم لنفاويبافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1Lymphoid Organs 1

•Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs

((Lymphocytes are generated)Lymphocytes are generated)

•Bone MarrowBone Marrow

•ThymusThymus

Page 2: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Primary (Central) Lymphoid Primary (Central) Lymphoid OrgansOrgans

استخوان استخوان مغز Bone MarrowBone Marrowمغزدر سنين پايين در همه استخوانهادر سنين پايين در همه استخوانهادر سنين باال در استخوانهاي دراز از بين مي روددر سنين باال در استخوانهاي دراز از بين مي رود محل بلوغ لنفوسيتهاي محل بلوغ لنفوسيتهايBBاست است

تيموس تيموسThymusThymus در سنين پايين فعال است و در سن باال تحليل مي روددر سنين پايين فعال است و در سن باال تحليل مي رود محل بلوغ لنفوسيتهاي محل بلوغ لنفوسيتهايTTاست است

Page 3: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Thymus

• small in an adult• site of T lymphocyte production• secretes thymosins

16-14

Page 4: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Figure 1-7

Page 5: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Secondary (Peripheral) Lymphoid Secondary (Peripheral) Lymphoid OrgansOrgans

•Lymphatic Vessels & Capillaries (Lymphatic Vessels & Capillaries (Lymphatic System )

•Lymph nodesLymph nodes

•SpleenSpleen

•Lymphoid tissues associated with mucosaLymphoid tissues associated with mucosa

1.1. Gut associated Tonsils, Gut associated Tonsils,

2.2. Peyers PatchesPeyers Patches

3.3. AppendixAppendix

4.4. Lymphoid Lymphoid FolliclesFollicles (Bronchial-Associated Lymphoid (Bronchial-Associated Lymphoid

Tissue (BALT), Mucosal-Associated Lymphoid Tissue Tissue (BALT), Mucosal-Associated Lymphoid Tissue

(MALT)(MALT)

Page 6: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Figure 1-7

Page 7: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Lymph Function

•Absorption of dietary fats & transports fats to

bloodstream

•Delivers foreign particles to lymph nodes

•Network of vessels that assist in circulating fluids

•Transports excess fluid away from interstitial spaces

•Transports fluid to the bloodstream

•Help defend the body against diseases

Page 8: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Lymphatic Pathways

Page 9: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Lymphatic Pathways

Page 10: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Lymph Movement

• action of skeletal muscles

• respiratory movements

• smooth muscle in larger

lymphatic vessels

• valves in lymphatic

vessels

Page 11: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Lymphatic Capillaries

• microscopic• closed-ended tubes• in interstitial spaces of most tissues

Page 12: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Tissue Fluid and Lymph

Lymph tissue fluid

that has entered a

lymphatic capillary

Page 13: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Lymphatic Vessels

•Lymphatic vessels merge into lymphatic trunks• lymphatic trunks drain into collecting ducts

Page 14: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

•Thoracic duct•Right lymphatic duct

Lymphatic Ducts

Page 15: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone
Page 16: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone
Page 17: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Figure 1-8 part 1 of 2

Page 18: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Lymph Nodes

Page 19: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Figure 1-8 part 2 of 2

Page 20: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Lymph Nodes

• cervical region• axillary region• inguinal region• pelvic cavity• abdominal cavity• thoracic cavity• supratrochlear region

16-12

Page 21: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Functions of Lymph Nodes

• filter potentially harmful particles

from lymph• immune surveillance by

macrophages and lymphocytes• areas of lymphocyte production

16-13

Page 22: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Spleen

• largest lymphatic organ• upper left abdominal quadrant• sinuses filled with blood• white pulp

• lymphocytes• red pulp

• red blood cells• lymphocytes• macrophages

16-15

Page 23: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Figure 1-9

Page 24: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Figure 1-9 part 1 of 3

Page 25: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Figure 1-9 part 2 of 3

Page 26: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Figure 1-9 part 3 of 3

Page 27: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Figure 1-10

Page 28: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Figure 1-10 part 1 of 2

Page 29: بافتها و اعضاء سيستم لنفاوي Lymphoid Organs 1 Primary (Central) Lymphoid OrgansPrimary (Central) Lymphoid Organs (Lymphocytes are generated) Bone MarrowBone

Figure 1-10 part 2 of 2