specific functions on specific to one side of the cortex rather than bilateral
TRANSCRIPT
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specific functions on specific to one side of the cortex rather than bilateral
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brain injuries “split brain” patients imaging studies
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left hemisphere◦ analytical abilities◦ quantitative skills◦ language
right hemisphere◦ music◦ spatial abilities◦ artistic abilities◦ emotions◦ facial recognition
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most well studied lateralized behavior◦ 95% of right handed have
speech on left◦ 70% of left handed have
speech on left
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aphasia – language deficit that cannot be attributed to motor, motivational, sensory or other explanations
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characterized by broken halted speech, absence of prosody
non-fluent aphasia
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Frontal lobe
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agrammatism◦ difficulty in comprehending or properly employing
grammatical devices, such as verb endings and word order.
anomia◦ Difficulty in finding (remembering) appropriate word
articulation◦ difficulty mispronouncing words
Copyright © Allyn & Bacon 2007 9
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Can’t just be motor or it wouldn’t be an aphasia
Grammatical issues with connecting words
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The lion was killed by the leopard.
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lion killed leopard.
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Can’t just be motor or it wouldn’t be an aphasia
Grammatical issues with connecting words
Non-fluent aphasia
Comprehension – fairly good; ability to read – fairly good
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Copyright © Allyn & Bacon 2007
Part of the Boston Diagnostic Aphasia Test
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Copyright © Allyn & Bacon 2007
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deficits observed depend on individual as well as where in this region damage occurs…◦ fmri studies…..
◦ INSULAR CORTEX – speech articulation?◦ apraxia?
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Copyright © Allyn & Bacon 2007
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fluid aphasia, deficits appear to be in comprehension; words are nonsensical
comprehension – poor reading ability - poor
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recognition of spoken words comprehension of meaning of words ability to convert thoughts into words
How do we test comprehension in someone that may have Wernicke’s Aphasia?
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surgical requirements
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injection of sodium amytal or sodium amobarbital – anesthetic
used to determine hemisphere important for speech
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split brain surgery
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initially – ◦ odd behaviors -
◦ subsequently – only can really tell by experimental manipulations in the lab
◦ Julian Jaynes – “Breakdown of the Bicameral Mind”
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Functional brain imaging◦ fMRI or PET used to see which half is active
when doing a language test
Copyright © 2006 by Allyn and Bacon
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Copyright © 2006 by Allyn and Bacon
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apraxia (of speech)- speech disorder with difficulty speaking correctly; not due to weakness or paralysis of speech muscles (NIDCD); complex motor commands
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acquired◦ most typically in adults after brain damage
developmental◦ appears present from birth◦ affects boys more than girls◦ other names – verbal dyspraxia, articulatory
apraxia, childood speech apraxia◦ different than developmental delay of speech
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cause or causes unknown may be related to language development may be neurological disorder no specific lesions or imaging studies
helpful family history of communication disorders
or learning disabilities
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difficulty putting sounds and syllables together in correct order
longer words more difficult than short inconsistent speech (say word and then
unable) children – comprehension much better than
expression
severity can vary widely
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http://www.youtube.com/watch?v=szjfC9K190U&feature=fvsr
http://www.youtube.com/watch?v=XNB0ihI2srQ&feature=related
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genetic component family studies twin studies complex in terms of genes complex in terms of etiology complex in terms of traits
◦ can include phonological, auditory, motor, visual deficits which make reading even more difficult