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tel. 949-419-0288 • fax. 949-419-0294 • email. [email protected] tel. 949-419-0288 • fax. 949-419-0294 • email. [email protected]. 949-419-0288 • fax. 949-419-0294 • email. [email protected] tel. 949-419-0288 • fax. 949-419-0294 • email. [email protected]

IntroductionChromaDex™ is the leading provider of high purity phytochemical reference standards and reference materials to the pharmaceutical, nutraceutical, dietary supplement, food and beverage, and cosmetic industries. Over the past five years, ChromaDex™ has built a world-class team of scientists, covering every aspect of natural products chemistry, in the quest of isolating compounds for our ChromaDex™ phytochemicals library.

ChromaDex™ has one laboratory facility. in the United States:

1) ChromaDex™ Boulder, Colorado

ChromaDex™ has all of the staff and equipment resources necessary to support ChromaDex’s™ research and manufacturing activities as well as provide a wide range of contract services for our clients.

ChromaDex™ is pleased to offer a complete suite of contract services “from Biomass to Bottle”:

1. Analysis2. Research3. Raw Material Selection4. Isolation and Synthesis(mg to kg)5. Process Development6. Method Development7. Validation8. Formulation Analysis9. Litigation Support10. Consultancy

“From Biomass to Bottle”

ChromaDex™ Boulder, Colorado

tel. 949-419-0288 • fax. 949-419-0294 • email. [email protected] tel. 949-419-0288 • fax. 949-419-0294 • email. [email protected]

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Testing for:- Marker compounds (Single or Multiple compounds)- Active ingredients/compounds- Fingerprinting (Qualitative)- Adulteration- Compound Characterization

Specialized Services:- Fractionation- Extraction- Isolation- Crystallization- Synthesis- Process Development

AnalysisThe core expertise of ChromaDex™ is Contract Analysis. These Contract Services are ideal for companies, teams, and individuals requiring everything from single sample analysis to complex method development or validation projects.

Below are just a few of the areas within the range of contract services offered by ChromaDex™:

Types of Analytical Services: - HPLC with UV, Diode Array, ELSD, RI, Fluorescent, or Mass Spec Detection - GC with FID or Mass Spec Detection - UV Spectrophotometric - FTIR - Karl Fischer Titration – For Water - TLC or HPTLC - NMR - Mass Spectroscopy - X-Ray Crystallography - Stability Studies

Types of Testing: - Raw Materials: Botanicals, Extracts, Intermediates, API….. - Raw Material Blends- Dietary Supplements- Foods and Beverages- Cosmetics - Pharmaceuticals- Finished Products: Tablets, Capsules, and Softgels- Impurity Profiling

For a complete list analysis services offered by ChromaDex™ or to inquire about a specific type of analysis you may require, please contact our technical services team at 949-419-0288 or [email protected].

Are you looking to develop a new botanical extract, natural product based drug, or phytochemical? Do you need larger quantities of non-commercially available or proprietary compound for research, analytical development, pre-clinical, or clinical studies? ChromaDex™ has extensive experience in isolation, semi-synthesis and synthesis of compounds from natural sources.

Whether you have your own process or if you want ChromaDex™ to develop the process for you, ChromaDex™ can handle all of your milligram to kilogram compound needs.

Isolation (mg/kg)

Types of compounds we have worked with: - Saponins, Triterpenes, Triterpene Glycosides - Flavonoids and Flavonoid Glycosides - Carotenoids - Quassinoids and Alkaloids - Fatty acids - Phenolic acids - Tannins - Quinones and Anthraquinones - Phytosterols and Steroid related structures - Liminoids - Macrolides - Many others….



ChromaDex™ helps customers develop efficacious and stable products. We advise on novel extracts and combinations which enable clients to achieve the desired goals and outcomes for each product. ChromaDex™ Formulation Services are intended for individuals and companies that are in the beginning stages of planning a product to place on the market as well as for existing products that lack a strong market presence.

ChromaDex™ Formulation Services - Dosage Form Specification Development - Manufacturing Process Optimization - Product Specification Development - Content Uniformity Evaluation - Dissolution Testing - Product/Compound Stability Assessment - Bio-Availability Evaluation

Formulation Analysis

ResearchChromaDex™ has a wide base of experience and expertise in the natural products area. Our base in isolation of reference standards and reference materials has led to the formation of a world class team of Natural Product Chemists, Analytical Chemists and Pharmacognosists. The ChromaDex™ Contract Research Group can help customers with a wide range of challenges, from sourcing appropriate raw materials and identification of new compounds to process development for large scale manufacture. This Contract Research Service is ideal for any sized organization that wants to leverage the experience of our expert team to maximize efficiency and achieve faster time-to-market.

Types of Contract Research Offered by ChromaDex™: - Literature Searches - Raw Material Selection: Plant and extract - Analytical Chemistry Research - Analytical Method Development - Isolation of Compounds - Characterization of Compounds - Process Development (Milligrams to Kilograms) - Formulation Analysis - Regulatory Review - Assessment of Toxicity and Safety “From Biomass to Bottle”, ChromaDex™ knows natural products.

Method Development/ImplementationAnalytical method development can be critical when working with natural products. Whether you are analyzing incoming raw materials, in-process samples, or finished dosage forms, using an appropriate method of analysis can be crucial to getting the right quality control data. ChromaDex™ has extensive analytical method development experience “From Biomass to Bottle”. New methods can be developed for a wide range of sample types, using any of the equipment in our laboratories. For a complete list of equipment capabilities, please refer to the Analytical Resources section of this brochure.


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Whether you are trying to manufacture a botanical extract or an active pharmaceutical ingredient starting with plant biomass, the single most important step will always be selecting the right biomass. The real intellectual property in developing natural based products or drugs lies in the plant. ChromaDex™ has been working with biomass suppliers all over the world for many years in the quest to isolate reference standards and reference materials. ChromaDex™ knows what to look for when it comes to quality of plant biomass. Raw Material Selection Services are ideal for customers who have limited access to raw material resources or do not have the capabilities to thoroughly validate material obtained from those suppliers.

ChromaDex™ Raw Material Selection Services: - Plant/Biomass Selection - Plant Species (including search for alternates) - Plant Part Selection (Root, rhizome, leave, whole plant…) - Harvest Time, Drying and Milling - Analytical Method Development (HPLC, GC, TLC…) - Extract Process Development (See Process Development) - Botanical Extract Selection

Process DevelopmentOnce you have selected your biomass and completed your research, now it’s time to scale up. ChromaDex™ works in all phases of project development, from process concept to full-scale production. This includes process research and innovation, scale-up, design, construction, operation of pilot plant or laboratory units, technology transfer, and optimization of manufacturing processes.

Process Development: - Analytical Development (Pre-process) - Process Research (milligrams and grams) - Process Development - Process Scale-up (grams to kilograms) - Research Evaluation and Coordination - Capital and Operating Cost Evaluation - Cost-Benefit Analysis - Project Management and Process Engineering - Detail Design - Process Transfer

ChromaDex™ has performed process development projects for: - Dietary Supplement Ingredients: Extraction and Purification - Cosmetic Ingredients: Extraction and Purification - Pharmaceutical Ingredients: Extraction, Purification and Synthesis

Teamed with our customers and other project partners, we refine processes to make them financially attractive and commercially successful. Our process development team also taps into ChromaDex’s™ industry experts as well as outside technical resources like universities, government and private research organizations, and equipment vendors.The real value for clients is in increased rate of innovation and reduced time-to-market for new products and processes. By working closely with the scientific, engineering, and business staff of its clients, ChromaDex™ builds a seamless project team, acting as an extension of the client’s own R&D capabilities.

Raw Material Selection

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Litigation SupportWhether you are making a dietary supplement or a pharmaceutical, almost any scientific process or product needs to be assessed for legal ramifications. ChromaDex™ can offer true end-to-end analytical services to both protect against litigation as well as support companies during litigation. ChromaDex™ has the most sophisticated analytical equipment available for supporting legal issues.

ChromaDex™ has performed litigation support such as: - Mediation where Analysis is Questioned - Product Adulteration - Prop 65 Claims - Expert Witness for Analytical Issues - Raw Material Disputes - Patent Infringement

ConsultancyProduct Development is not just a science, it’s an art. Starting with an idea and getting to the finished product requires extensive planning, testing, and validation. ChromaDex™ Consultancy gives your company the best intelligence, analytical methods, marketing resources and litigation services available.

Whether you are assessing your marketing position and materials, developing or investing in a new product, implementing GMPs, or restructuring your company, ChromaDex™ Consultancy can support your needs at every phase of product life cycle.

ChromaDex™ Consultancy Specialties - Product/Marketing Solutions for the US or International Markets - Qualifying and Assessing Labeling and Advertising Claims - Ensuring Compliance with Regulatory Requirements - Determining and Establishing Best-fit Business Practices - Defining Regulatory Meaning and Impact - Providing Regulatory Response and Potential Change Strategies - Competitive Analysis and Market Assessment - Infrastructure Analysis and Operations Assessment

ChromaDex™ Consultancy offers a complete package of solutions for your business needs. While the focus of the consulting service is from a regulatory perspective, our goal is to maximize the impact of your product and company on the marketplace. Expert advice, guidance and strategic applications are tailored to help you achieve your business goals and benchmark new company successes. ChromaDex™ Consultancy enables you to identify potential opportunities and act on them while moving your business forward through this highly competitive and regulated industry.




No matter how well a developed method is intended to perform, analysts need to confirm whether or not the method works when applied in the quality control environment. Analytical method validation shows that an analytical method is able to accurately determine the level(s) of analytes of interest in a specified matrix. Validation of method for complex matrices, like dietary supplements or plant-based extracts, can be very challenging. ChromaDex™ Method Validation Services are designed for companies who want their method fully or partially validated, according to specific parameters defined for the method and matrix.

ChromaDex™ Method Validation Services - Full Validation - Partial Validation - Cross Validation

Fundamental Parameters for Method Development - Accuracy - Precision - Selectivity - Linearity - Limit of Detection(LOD)/Limit of Quantitation - Ruggedness - Robustness

Full ValidationFull method validation services are designed to cover the complete range of Validation Parameters, as above. Full validation services can be tailored to suit each individual client’s needs, ranging from Single Laboratory to Multi-Laboratory validation

Partial ValidationPartial method validation services are designed to monitor only a few of the validation parameters, which may be crucial to the performance of the method. Partial validation can also be performed in a single or multi-laboratory environment.

Validation

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Analytical ResourcesGC (Gas Chromatography)1. Two HP 5890 Series II, plus GOs with auto samplers, split/splitteless, injector, FID and TCD2. Agilent 6890 GC with autosampler, split/splitless, FID, and Agilent 5973 Mass Selective Detector

MS (Mass Spectrometry)1. Finnigan Navigator single quad with APCI and ESI ion sources.2. Finnigan LCQ Deca ion trap with APCI and ESI ion sources.

HPLC (High Performance Liquid Chromatography)1. Twelve Agilent 1100 with quaternary pumps, autosamplers (six), variable wavelength detectors (four), fluorescence detector (one) and ELSD (one).2. TSP/SP AS1000 (with autosampler, variable wavelength detector, SpectroFocus detector, forward optical scanning detector, UV detector)3. Three Dionex HPLC (with Autosampler, UV detector)

HP-TLC (High Performance-Thin Layer Chromatography)1. Two CAMAG Automatic TLC sampler 4’s2. Alpha Innotech FluorChem 8900 Imaging system with cooled CCD camera (-30 °C absolute) and dual epi-UV at 254 and 365 nm, white light and densitometry capabilities3. CAMAG TLC Scanner 34. BioLuminizer Imaging system with cooled CCD camera and software

Prep Scale Chromatography1. Custom Built Carver Prep Scale Chromatography Unit2. Waters Prep LC 2000 with 490E programmable multi-wavelength detector and Gilson 206 fraction collector3. Septech ST500 with variable wavelength monitor and GP-900 controller4. Merck Novaprep 5000 integrated prep scale HPLC

Microbiology1. Neogen Soleris 128 System (Incubator/Detector)2. Neogen Genequence Reader/Washer

Miscellaneous1. Two Camile Clark Automated Glass Reactors with Sampletek automated sampling units (250 mL and 1L)2. PAR Hydrogenator high pressure reaction system (automated stirrer, temperature and pressure control)3. Podbielniak centrifugal counter-current liquid/liquid extractor4. PerkinElmer Paragon 500, FTIR Spectrometer5. Genevac HT-4 Centrifugal Evaporator6. Three Hotpack stability chambers7. Fitzmill Hammermill and UDY Cyclone sample mill8. Multiple microbalances and analytical balances9. Three 20L Buchi rotovaps10. Ten 2L Buchi rotovaps11. One AquaStar Karl Fischer titrators & ovens12. Denver Instrument IR-200 moisture analyzer13. Cary 50 Bio UV - Visible spectrophotometer14. GenePix 4200A Microarray Scanner




Microbiological TestingCHroMADex™ iS PLeASeD To AnnounCe THe LAunCH oF A new Line oF MiCrobioLoGiCAL TeSTinG SerViCeS.As the industry leader in Phytochemicals, ChromaDex™ now has the expertise, equipment, and facilities to offer you quick and accurate microbial testing at a fraction of the cost you would pay elsewhere.

CHroMADex™ oFFerS new STATe-oF-THe-ArT MiCrobiAL TeSTinG TeCHnoLoGy. This technology allows for testing of a greater variety of sample matrices, quicker turn around times, and lower costs. We have defined package deals at special prices or our experts will work directly with you to help you determine which assays best suit your needs.

Test Panels:

FULL MICROBIOLOGICAL PANEL #1

Panel Includes: Service Code# CDA-00100254-ARS

1. Total aerobic count Sample Amount 65g

2. Total yeast and mold Turn Around Time 4-5 Days

3. Enterobacteriaceae

4. Salmonella Price per Sample

5. Escherichi Coli 1 2 to 4 5 to 9 10+

6. Staphylococcus aureus




2. Total yeast and mold Turn Around Time

3. Coliform Price per Sample

4. Staphylococcus aureus 1 2 to 4 5 to 9 10+

5. Escherichi Coli





3. Coliform


5. Escherichi Coli


7. Pseudomonas Price per Sample

8. Salmonella 1 2 to 4 5 to 9 10+

9. Listeria





3. Coliform


5. Escherichi Coli Price per Sample

6. Pseudomonas 1 2 to 4 5 to 9 10+




Microbiological TestingTOTAL AEROBIC COUNT

Service Code# CDA-00100087-ARS

Sample Amount 25g

Turn Around Time 2-3 Days

Price per Sample

1 2 to 4 5 to 9 10+

TOTAL YEAST AND MOLD PANEL


Sample Amount 25g


Price per Sample

1 2 to 4 5 to 9 10+

COLIFORM


Sample Amount 25g


Price per Sample

1 2 to 4 5 to 9 10+

ESCHERICHI COLI


Sample Amount 25g


Price per Sample

1 2 to 4 5 to 9 10+

ENTEROBACTERIACEAE


Sample Amount 25g


Price per Sample

1 Sample 2-4 Samples 5-9 Samples 10+ Samples

PSEUDOMONAS


Sample Amount 25g


Price per Sample

1 2 to 4 5 to 9 10+

LISTERIA


Sample Amount 25g


Price per Sample

1 2 to 4 5 to 9 10+

SALMONELLA


Sample Amount 25g


Price per Sample

1 Sample 2-4 Samples 5-9 Samples 10+ Samples

STAPHYLOCOCCUS AUREUS


Sample Amount 25g


Price per Sample

1 2 to 4 5 to 9 10+

ESCHERICHI COLI 0157:H7


Sample Amount 50g


Price per Sample

1 2 to 4 5 to 9 10+

Individual Assays:




Cost per Sample(US$)

Code Bioassay Pharmacological Relevance 1 Sample2-24

Samples25-99

Samples100+

SamplesTurn Around Time(TAT)

CDA-BCA01-ATR Alpha - Amylase Inhibition Assay Obesity, Diabetes 2 weeks

CDA-BCA02-ATR Alpha - Glucosidase Inhibition Assay Anti-diabetic 2 weeks

CDA-BCA03-ATR Beta - Glucuronidase Inhibition Assay Hepatoprotective, Axillary odour 3 weeks

CDA-BCA04-ATR ABTS Radical Scavenging Assay Antioxidant 3 weeks

CDA-BCA05-ATR Acetylcholinesterase Inhibition Assay* Cognition enhancement 3 weeks

CDA-BCA06-ATR Aryl Sulphatase Inhibition Assay Axillary odor 3 weeks

CDA-BCA07-ATR Butyrylcholinesterase Inhibition Assay* Cognition enhancement 2 weeks

CDA-BCA08-ATR Collagenase Inhibition Assay Anti-ageing / Anti-wrinkle 4 weeks

CDA-BCA09-ATR Nitric-oxide Scavenging Assay Antioxidant, Alzheimer’s disease 3 weeks

CDA-BCA10-ATR Superoxide Anion Scavenging Activity (PMS-NADH system)

Antioxidant 3 weeks

CDA-BCA11-ATR DPP IV Inhibition Assay Anti diabetic, obesity 4 weeks

CDA-BCA12-ATR DPPH Assay* Antioxidant 3 weeks

CDA-BCA13-ATR Elastase Inhibition Assay Anti wrinkle, Anti-ageing 3 weeks

CDA-BCA14-ATR Hyaluronidase Inhibition Assay Anti-inflammatory. Anti wrinkle 3 weeks

CDA-BCA15-ATR Hydroxyl Radical Scavenging Assay Antioxidant 3 weeks

CDA-BCA16-ATR Lipase Inhibition Assay Obesity 3 weeks

CDA-BCA17-ATR 15 - Lipoxygenase Inhibition Assay Anti-inflammatory 3 weeks

CDA-BCA18-ATR Trypsin Inhibition Assay Anti-inflammatory 3 weeks

CDA-BCA19-ATR Xanthine Oxidase Inhibition Assay Gout 3 weeks

CDA-BCA20-ATR TC- PTPase Inhibition Assay TC-PTPase inhibitors are likely to inhibit PTP-1B)

4 weeks

CDA-BCA21-ATR PTP-IB Inhibition Assay Anti-diabetic, Anti-obesity 4 weeks

CDA-BCA22-ATR Aldolase Inhibition Assay Obesity 3 weeks

CDA-BCA23-ATR COX-I Inhibition Assay Done along COX II assay to know selectivity

4 weeks

CDA-BCA24-ATR COX II Inhibition Assay Inflammation 4 weeks

CDA-BCA25-ATR Phosphodiesterase –I Inhibition Assay Arthritis 4 weeks

ChromaDex™ is pleased to announce the launch of a new line of bioassay services to complement our line of phytochemicals and contract analysis services. ChromaDex™ now offers over FiFTy different bioassays covering a wide range of pharmacological relevance.

As the industry leader in Phytochemicals, ChromaDex™ now has the expertise and uniquely powerful bioassays to provide you with biologically relevant experimental results. Our experts will work directly with you to design and perform bioassay studies that are customized to your specific needs. We utilize our proven technologies and materials, and maintain strict control over raw materials and equipment. You can trust that your samples are handled with the utmost care, expertise, and confidentiality.

ChromaDex™ Bioassay Services is a unique resource that you can use to increase the efficiency of your research. We have a dedicated team of scientists and technicians, working in specialized state-of-the-art facilities to perform your contract research or assay optimization. We deliver results quickly, with unequaled accuracy, value, and reproducibility.

Call today to learn how to move your research forward with ChromaDex™ Bioassay Services.

Bioassays Services

A. BIOCHEMICAL ASSAYS

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A. BIOCHEMICAL ASSAYS (continued)

B. CELLULAR ASSAYS Cost per Sample(US$)


Samples12+

SamplesTurn around Time(TAT)

Lymphocyte Proliferation Assays

CDA-CA01A-ATR a. Naïve and LPS treated lymphocytes Immune modulation 4 weeks

CDA-CA01C-ATR c. Naïve and Con A treated lymphocytes Immune modulation 4 weeks

CDA-CA02-ATR NO Release (in J774A.1 macrophages) Immune stimulation 4 weeks

CDA-CA03-ATR NO scavenging (in LPS prestimulated macro-phges)

Anti-oxidant 4 weeks

CDA-CA04-ATR Macrophage Phagocytosis Immune modulation 4 weeks

CDA-CA05-ATR LTB4 release assay Anti-inflammatory 4 weeks

CDA-CA06-ATR Hepatoprotection assay using t-BH Hepatoprotection 4 weeks

CDA-CA08-ATR Histamine release assay Anti-inflammatory, Anti-allergy 4 weeks

CDA-CA12-ATR PGE2 release J774A.1 macrophage cells Anti-inflammatory 4 weeks

CDA-CA13-ATR Insulin Release Anti-diabetic 4 weeks

CDA-CA14-ATR Collagen release NIH-3T3 Anti-wrinkle 4 weeks

CDA-CA15-ATR TXB2 Release 4 weeks

Cost per Sample(US$)


Samples25-99

Samples100+

SamplesTurn Around Time(TAT)

CDA-BCA26ATR Protein Phosphatase-1 Inhibition Assay Cognition enhancement 3 weeks

CDA-BCA28-ATR Thymidine phosphorylase (TP) Inhibition Assay Anti-psoriasis 4 weeks

CDA-BCA29-ATR RHO-Kinase (ROCK-II) new Erectile dysfunction/Male impotency 4 weeks

CDA-BCA31-ATR Angiotensin converting enzyme(ACE) inhibition new

Hypertension 4 weeks

CDA-BCA32-ATR Tyrosinase inhibition new Skin whitening 4 weeks

CDA-BCA33-ATR PARP inhibition new Neuro degenerative disorders 4 weeks

CDA-BCA34-ATR PLA2 inhibition new Anti-inflammatory 4 weeks

CDA-BCA35-ATR PAF acetylhydrolase inhibition new Atherosclerosis 4 weeks

CDA-BCA36-ATR IKK-Beta(NF-B kinase) inhibition new Anti-Diabetic 4 weeks

CDA-BCA37-ATR Glucose-6-phosphatase new Anti-Diabetic 4 weeks

CDA-BCA38-ATR P70S6 Kinase Inhibition Anti-Diabetic 4 weeks

CDA-BCA39-ATR ORAC(hydrophyllic) Antioxidant 2 weeks

CDA-BCA40-ATR SIRT-1 Activation 3 weeks

CDA-BCA41-ATR Cholesterolesterase Inhibition 2 weeks

CDA-BCA42-ATR MGL Inhibition 3 weeks

CDA-BCA43-ATR ORAC(Lipophilic) Antioxidant 2 weeks

CDA-BCA44-ATR PPAR Gamma receptor functional assay - agonist

3 weeks

CDA-BCA45-ATR Advanced Glycated Endproducts Inhibition(AGE)

3 weeks

CDA-BCA46-ATR SGK-1 3 weeks

CDA-BCA47-ATR 20S Proteosome 3 weeks

CDA-BCA48-ATR Aldose reductase 3 weeks

Bioassays Services


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Quantity of sample required:1 gm sample in a properly closed air tight container. In case the sample is precious and expensive, lesser quantities can also suffice (Please specify the assays for us to provide the minimum sample quantity requirement).

Turn Around Time:The table indicates typical turn around time required for performing the assays. Turn Around Time may vary depending on the sample and project details, please enquire about the exact turn around time, at the time of order

General notes: Samples with poor solubility profile in aqueous buffers may not be suitable for analysis.

IC50

/ EC50

values can be calculated only for active samples. For samples which do not have sufficient activity the results may not be amenable to statistical analysis or graph plotting and they will be reported as such. In most cases, IC50 will be calculated using linear regression analysis.New assays are added frequesntly; please send us a request for a comprehensive list.

A ChromaDex Sample Submission form should be filled and sent with all samples for evaluation.

Details about methodology adopted, importance and relevance of these assays are available on request. For a few assays, positive control data may not be available.

For all bio-chemical assays, each sample is normally tested at five(5) different concentrations, in duplicate(2). However for some specific assays a different approach is adopted to obtain reliable results. For ex. the PPAR receptor functional assay is performed in agonist mode using 12 concentrations in triplicate. EC

50

is presented only when concentration dependant response is observed. Similarly SIRT-1 assay is performed in activation mode with 5 concentrations in 5 replicates and the results are analyzed using a suitable test of hypothesis. (Ex: ANOVA)

The prices indicated for cell based assays include determination of the measured parameter at five pre-determined concentrations, for herbal extracts (0.01, 0.1, 1, 10, 100 µg/ml) and for pure compounds (10-9, 10-8, 10-7, 10-6, 10-5 M), with 6 replicates per concentration. Parallel cell viability estimation is also included in the same cost. These concentrations can be modified as per user request. Same cost is applicable for follow up IC

50 / EC

50 determination of a sample, at requested

12 concentrations, with 3 replicates per concentration.

Samples should be preferably free of preservatives for testing in cellular assays. In case preservatives have been added, information should be provided as such samples will require additional testing of preservative controls for obtaining reliable results.

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•

•

•

•

•

•

•

•

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C. MISC. ASSAYS Cost per Sample(US$)


Samples25-99

Samples100+

SamplesTurn Around

Time

CDA-MA01-ATR Brine Shrimp Lethality Test++ Non specific general bioassay 3 weeks

CDA-MA02-ATR Anti-Staphylococcus aureus* (MTCC 737) Antibacterial activity 3 weeks

CDA-MA03-ATR Anti-Escherichia coli (MTCC 1687) Antibacterial activity 3 weeks

CDA-MA04-ATR Anti-Kleibsiella pnemoniae (MTCC 109) Antibacterial activity 3 weeks

CDA-MA05-ATR Anti-Pseudomonas aeruginosa (MTCC 1688) Antibacterial activity 3 weeks

CDA-MA06-ATR Anti-Proteus vulgaris (MTCC 1771) Antibacterial activity 3 weeks

CDA-MA07-ATR Anti-Staphylococcus epidermidis (MTCC 435) Antibacterial activity 3 weeks

CDA-MA08-ATR Anti-Propionibacterium acne (MTCC 1951) Antibacterial activity 3 weeks

CDA-MA09-ATR Anti-S.mutans* (MTCC 890) Antibacterial activity 3 weeks

CDA-MA10-ATR Anti-S.salivarius (ATCC 13419-derived) Antibacterial activity 3 weeks

CDA-MA11-ATR Anti-S.sanguis (ATCC 10556-derived) Antibacterial activity 3 weeks

CDA-MA12-ATR Anti-Candida albicans (MTCC 183) Antifungal activity 4 weeks

CDA-MA13-ATR Anti-Trichophyton rubrum (MTCC 296) Antifungal activity 6 weeks

CDA-MA14-ATR Anti-Microsporum gypseum (MTCC 2819) Antifungal activity 6 weeks

CDA-MA15-ATR Caenorhabditis elegans Lethality Antihelmintic

Bioassays Services

0 introduction · ... capsules, and softgels ... now it’s time to scale up. ... scale-up,...

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