000135 amniotic membrane transplantation using fibrin glue in pterygium surgery
TRANSCRIPT
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8/18/2019 000135 Amniotic Membrane Transplantation Using Fibrin Glue in Pterygium Surgery
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Amniotic Membrane Transplantation Using
Fibrin Glue in Pterygium Surgery
Sirel G. Güngör, MD
Cem ü!ü"er#önme$, MD
%onca A. A"o&a, MD Baskent University, School of Medicine
Department of Ophthalmology, AnkaraTurkey
The authors acknowledge no financial interest
in the subject matter of this presentation
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'ntro#uction
Amniotic membrane transplantation
(AMT) is a t*erapeutic option +or ocular
sur+ace #isor#ers
• Persistent epit*elial #e+ects
• Deep stromal #e+ects
•
Stem cell #eciency• Pterygium
• Symblep*aron
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Purpose
To e&aluate t*e e++icacy an# sa+ety o+
+ibrin glue +i-ation o+ amniotic
membrane an# to compare t*e
results it* suture +i-ation in surgery
+or primary pterygium
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Met*o#s
• Prospecti&e,
ran#omi$e# clinical
stu#y o+ /0 eyes (/0
patients) it* primarypterygium #i&i#e# into
1 groups
• Surgical met*o#
2-tensi&e pterygium
remo&al an# AMT
Group 3
• Amniotic membrane
as +i-ate# it* 450
6icryl suturesGroup 1
• Fibrin glue (Tisseel
VH, Baxter AG,
Vienna, Austria) asuse#
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Met*o#s
• Clinical e-amination an#
#igital p*otograp*ing
as per+orme# at eac*
&isit
• 7peration time,
sub8ecti&e sensation o+
pain, complications an#recurrence rates ere
recor#e#
• Sub8ecti&e pain scale 9
0 none, no pain
1 &ery mil#, presence o+pain but easily tolerate#
2 mil#, pain causingsome #iscom+ort
3 mo#erate, pain t*atpartially inter+eres it*usual acti&ity or sleep
4 se&ere, pain t*atcompletely inter+eresit* usual acti&ity orsleep
9Lim-Bon-Siong et al Am : 7p*t*almol 3;;4< 31=>3?;
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@esults
Group 3 Group 1 !
Mean
operationtime
(minutes) 34. B5 1.1 33.1 B5 ./ pE0.0=
@ecurrence
rate () =.4 =.= p0.0=
Mean +olloup time(mont*s) 3?.4 B5 /.1 3=.; B5 1.= p0.0=
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@esults
'n group 1• Signi+icantly less symptoms at
postoperati&e #ay 3 an# • Postoperati&e signs o+ *yperemia an#
c*emosis ere signi+icantly less obser&e#• 1 eyes #e&elope# gra+t #e*iscence a+ter
surgery, *ic* ere success+ully re+i-ate#it* +ibrin glue
• Ho ot*er complications ere obser&e#
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Clear cornea a+ter e-tensi&e pterygium remo&al an# AMT it* +ibrin glue at 3st
mont*
Preoperati&e primary pterygium
Clear cornea a+ter e-tensi&e pterygium
remo&al an# AMT it* +ibrin glue at 3st #ay
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Preoperati&e primary pterygium
Clear cornea a+ter e-tensi&e pterygium remo&al
an# AMT it* 450 6icryl sutures at 3st #ay
Clear cornea a+ter e-tensi&e pterygium remo&al an# AMT it* 450 6icryl sutures at
3st mont*
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Discussion
AMT it* sutures• Prolonge# operating time
• Postoperati&e #iscom+ort
• Suturerelate# complications suc* as abscess an#granuloma +ormation
AMT it* +ibrin glue• Completely bio#egra#able
• 2asy to +i-ate t*e amniotic membrane an# s*orter
operation time
• Iess patient #iscom+ort
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Conclusion
Fi-ation o+ amniotic membrane using
+ibrin glue
•
2++ecti&e an# sa+e met*o#• @e#uce# t*e operation time
• 'mpro&e# postoperati&e com+ort
• Ho a##itional e++ect on re#ucingpterygium recurrence
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HAM2> %onca Ay#Jn A"o&a, M.D.
T'TI2> Pro+essor in 7p*t*almology
DAT2 AHD PIAC2 7F K'@TL>
7ctober 13, 3;?0, Tur"ey3;4> Doctor o+ Me#icine, 'stanbul
Uni&ersity, Sc*ool o+ Me#icine
3;;0> 'stanbul Uni&ersity, Sc*ool o+Me#icine,Department o+ 7p*t*almology
1000>Pro+essor o+ 7p*t*almology,Kas"ent Uni&ersity, Sc*ool o+Me#icine, Department o+
7p*t*almology, An"ara, Tur"ey1001> C*airperson, Kas"ent
Uni&ersity, Sc*ool o+ Me#icine,Department o+ 7p*t*almology,
An"ara, Tur"ey
HAM2> Sirel Gür Güngör, M.D.
T'TI2> @esi#ent in 7p*t*almology
DAT2 AHD PIAC2 7F K'@TL>
February 3=, 3;;, Tur"ey100> Doctor o+ Me#icine, An"ara
Uni&ersity, Sc*ool o+Me#icine
1001004 > @esi#ent, Ka"entUni&ersity, Sc*ool o+Me#icine, Department o+7p*t*almology, An"ara,Tur"ey
HAM2> Cem ü!ü"er#önme$, M.D.
T'TI2> Fello in 7p*t*almology
DAT2 AHD PIAC2 7F K'@TL>
7ctober ;, 3;=, Tur"ey3;;;> Doctor o+ Me#icine,
Lacettepe Uni&ersity, Sc*oolo+ Me#icine
100 > Ka"ent Uni&ersity, Sc*ool o+Me#icine,Department o+ 7p*t*almology