001hypertensive disorders in pregnancy.pdf

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  • 7/27/2019 001Hypertensive Disorders in Pregnancy.pdf

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    Hypertensive Disorders

    in

    Pregnancy

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    Pregnancy Induced Hypertension

    Terms :

    PIH development of HPN ( BP> 140 /90 duringsecond half of pregnancy, occurs in previouslynormotensive woman.

    Pre-eclampsia renal involvement leads toproteinuria

    Eclampsia CNS involvement leads to seizures

    HELLP clinical picture dominated by

    hematologic and hepatic signs and symptoms. Chronic HPN elevation of BP occurs before 20

    weeks gestation.

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    Hypertensive Disorders of Pregnancy

    a potentially life-threatening disorder

    that usually develops after 20 week

    of pregnancy

    most common in nulliparous women cause is unknown.

    systemic vasospasm occur, affecting

    every organ system

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    Two categories ofPIH

    1 .Preeclampsia Mild / Severe

    - non convulsive form of disorder

    - maybe mild or severe

    - occurs after 20 weeks gestation

    - higher incidence in the low

    socioeconomic group

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    Factors that increases the risk for developing

    Pre-eclampsia

    1- Primigravidas age 40 yrs and above

    2- Women with chronic hypertension /

    Renal disease

    3- Low socioeconomic status

    4- Young maternal age > less than 17 yrs.

    5- Women with DM or Multiple pregnancies

    6- Dietary deficiencies

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    2. Eclampsia -

    - convulsive form of the disorder

    - occurs between 24 weeks gestation and

    the end of the first post partum week

    - higher incidence with first pregnancies,

    multiple gestations and history of vascular

    disease

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    Assessment Findings:

    1. BP over 140/90 mmHg or an increaseof 30 mmHg systolic and 15mmHgdiastolic over baseline taken on 2

    occasions 4-6 hrs. apart. 2. Increase in generalized edema

    associated with a sudden weight gain ofmore than 5lbs.( 2.3 Kg) per week

    3. Proteinuria

    4. Convulsion and or coma

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    SIGNIFICANT CHANGES IN PIH

    Decreased renal perfusion reducesGFR( Glomerular Filtration Rate)

    Reduced blood flow to kidneys

    causing glomerular damage Loss of PRO from kidneys reduces

    colloid osmotic pressure and allowsfluid to shift from vascular to interstitial

    spaces Hypovolemia additional angiotensin II

    and aldosterone (retention of Na andwater)

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    Decreased circulation to the liver impaired liver function (hepatic edema

    and subscapular hemorrhage) Vasoconstriction of cerebral vessels -

    small cerebral hemorrhages ( spotsbefore eyes, blurred vision)

    Decreased colloid oncotic pressure pulmonary capillary leak ( pulmonaryedema)

    Decreased placental circulation infarctions (abruptio placenta)

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    Changes Associated with PIH

    Effects on the

    Interstitial

    History of Systematic Vasospasm

    Effects on the

    Vascular system

    Vasoconstriction

    Impaired organ

    Perfusion

    Hypertension

    Effects on the

    renal system

    Reduced glomerularFiltraction rate: Increased

    Glomercular membrance

    permeability

    Increased serum bloodUrea nitrogen and

    creatinine

    Oliguria and protelnuria

    Fluid diffusion from

    Vascular space into

    Interstitial space

    Effects on the

    Interstitial

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    Preventive Measures for PIH:

    1. Adequate prenatal care close attentionto weight gain, monitoring BP and urinary

    protein.

    2. Low dose aspirin (6080 mg /day) per

    doctors order suppresses synthesis of

    thromboxane that causes vasoconstrictionand platelet aggregation.

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    3. Calcium supplementation for less

    sensitivity to the pressor effects of

    angiotensin II and have a lower incidence ofHPN.

    4. Sedatives ( Diazepam or Phenobarbital)given if MgSO4 fails in Eclampsia to bring

    seizures under control.

    5. Environment modification

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    Manifestations / Classic Signs :

    1. Generalized edema rapid weight gaindue to fluid retention , present in lower

    legs, hands and face ( tightening ofwedding ring )

    2. Hypertension BP 140/90;30 mmHgsystolic and 15mmHg diastolic

    3. Proteinuria

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    Symptoms :

    Continuous headache, drowsiness, mentalconfusion ( poor cerebral perfusion )

    Visual disturbances ( blurring of vision )

    arterial spasms, edema of retina Numbness or tingling of hands and feet

    compression of nerves by retained fluid

    Epigastric pain or upset stomach distention of hepatic capsule

    Decreased urinary output poor perfusion

    of the kidneys > acute renal failure

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    Nursing Considerations for Pre-eclampsia

    1. Sedentary activity for most of the day or bedrest.

    2. Keep record of fetal movements or kick

    count 3. Check BP 2-4x a day ( same arm, same

    position)

    4. Weigh daily( same time, same scale)

    5. Advice on dietary regulation - low or no salt,

    protein rich foods

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    6. Administration of anti-hypertensives and diureticsper doctors order Hydralazine, Nifedipine orLabetalol

    7. Anticonvulsant Meds MgSO4 ( to preventconvulsions), Phenytoin , Nifedifine

    - Check DTR before administration

    - Keep CA Gluconate on standby ( antidote ) -Monitor urine output ( shd. be 30 ml/hr)

    RR ( 12 BPM )

    Side Effects: CNS depression, depression of

    Respiratory Center 8. Environment should be kept quiet with dim lights

    9. Seizure precautions and prevent injury foreclampsia

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    General Nursing Measures:

    1. High protein, low salt diet

    2. Adequate fluid intake

    3. Bed rest in lateral position

    4. Antihypertensive methyldopa,hydralazine

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    5. Magnesium sulfate have

    antidote ready at bedside (Cagluconate)

    6. Monitor VS, level of consciousness

    and DTR

    7. Maintain seizure precautions

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    Symptoms of Magnesium Sulfate Toxicity

    1. Decreased deep tendon reflexes or

    absent

    2. Muscle flaccidity

    3. Central Nervous System depression /altered sensorium ( confusion, lethargy,

    slurring speech, drowsiness, disorientation )

    4. Decreased respiratory rate - < than 12

    breaths per minute

    5. Decreased renal function

    6. Sweating and flushing sensations

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    Severe Complications of Eclampsia:

    1. Seizures ( eclampsia)

    2. Cerebral edema

    3. Stroke

    4. Abruptio placenta

    5. Fetal death

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    Assessment of Edema

    Characteristics

    Minimal edema of lower extremities

    Marked edema of lower extremities

    Edema of lower extremities,face

    hands and sacral area

    Generalized massive edema that

    include ascites

    Grade

    + 1

    + 2

    + 3

    + 4

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    Chronic Hypertensive Vascular Disease

    (CHVD )

    Persistent hypertension before pregnancybefore 20th week of gestation or beyond

    42nd wk. postpartum.

    Seen in older women who are obese and

    those with DM.

    Can be attributed to heredity, race

    Can lead to pre-eclampsia , and seen onthe basis of rise in BP, sustained

    proteinuria and generalized edema

    Management :

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    Management :

    High protein diet with adequate salt

    Advise woman to weigh herselfevery 3 days to detect abnormal

    weight gain

    Anti hypertensive drugs if diastolicis consistently higher than 90

    mmHg. Anti-hypertensive drugsshould not be teratogenic.(methyldopa )