03-cogs11-neuronal communication
TRANSCRIPT
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cation anion
+_
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OUTSIDE OF CELL
INSIDE OF CELL
K+
Cl-Na+
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
K+ A-
Na+ Cl-
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Na-K Pump Animationhttp://highered.mcgraw-hill.com/olc/dl/120068/bio03.swf
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Na+ Opens
K+ Opens
Na+ becomes Refractory
K+ continuesto leave cell.Causing themembranepotentialto return tothe restingpotential.
K+ channelsclose.
Na+ channelsreset, readyfor action again!Extra K+ outside
diffuses away.
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Lai et al. Nature Reviews Neuroscience 7, 548–562 (July 2006) | doi:10.1038/nrn1938
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Synaptic Transmission