04 pds apf+ cmyk - aptar · advanced preservative free˜plus gold standard for unpreserved sprays...
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![Page 1: 04 PDS APF+ CMYK - Aptar · Advanced Preservative Free˜Plus Gold standard for unpreserved sprays Outstanding Spray Performance Benefi ts APF˜Plus spray pattern – Soft and gentle](https://reader030.vdocuments.net/reader030/viewer/2022040918/5e947c4d2df4c937df630efa/html5/thumbnails/1.jpg)
Advanced Preservative Free�Plus
aptar.com/pharma Delivering solutions, shaping the future.
Advanced Preservative Free�Plus
Closure
Accessory
Dose volume: 50�µl to 140���µl
Snap-onSize: 20�mm
Protection cap
ScrewSize: 18�mm
![Page 2: 04 PDS APF+ CMYK - Aptar · Advanced Preservative Free˜Plus Gold standard for unpreserved sprays Outstanding Spray Performance Benefi ts APF˜Plus spray pattern – Soft and gentle](https://reader030.vdocuments.net/reader030/viewer/2022040918/5e947c4d2df4c937df630efa/html5/thumbnails/2.jpg)
Advanced Preservative Free�Plus
Gold standard for unpreserved sprays
Outstanding Spray Performance
Benefi ts
APF�Plus spray pattern
– Soft and gentle mist
– Metal free fl uid path
– Sterile according to ISO11137
– Tip design prevents crystallization and clogging
– Purely mechanical barrier, no additives
– Supporting successful brands globally
– Spring loaded Tip-Seal mechanism
– Filter membrane in air fl ow
Standard spray pattern
APF�Plus advantages
– Fine mist
– Round spray pattern
– Long and stable fully developed phase of spray
– Unvented preservative free system
– Pouch system allows for 360° use
– Convenient and intuitive handling
TSIT (Tip Seal Integrity Test)
Submersed actuation in Pseudomonas aeruginosa suspension
Qualifi ed with challenging microbiological tests
Full 360° Functionality
CVIT(Closure Ventilation Integrity Test)
Closure and fi lter challenge with Bacillus atrophaeus spores
360°