New Departmental Research Grant AwardDr. W. Daniel Tracey of the Division of Basic Sciences and Director of the Molecular Genetics of Pain Signaling Laboratory received a 4-year $1,193,200 NIH R01 Grant from the National Institute of General Medical Sciences (NIGMS) entitled “A Genome-Wide Analysis of Nociception Molecules, from Express to Function”.

A thorough understanding of the molecular machinery that operates in nociceptive

sensory neurons will lead to greater understanding of the protective molecular mechanisms of acute pain. To identify nociception molecules, we previously carried out a genetic screen for nociception defective mutants using the fruitfly Drosophila melanogaster. This led to our discovery of the painless gene, which shows enriched expression in nociceptive sensory neurons and is required for acute nociception. The painless gene, as well as a related gene named dTRPA1, encode homologues of TRPA1. Human mutations in TRPA1 mutations lead to familial episodic pain syndrome (FEPS) and TRPA1 is highly expressed in nociceptor neurons. We have identified pickpocket as a critical regulator of mechanical nociception which is specifically expressed in Drosophila nociceptors. This research project will identify other genes expressed in nociceptor neurons of Drosophila and to test the functional requirement of those genes in nociception. In the short term, these studies will provide critical insight into molecular and cellular mechanisms of nociception using a high throughput approach that is made possible using Drosophila. In the long term, these studies may eventually allow for the identification of evolutionarily conserved mechanisms that contribute to human nociception.

2011 SEA-HVO Fellowships AnnouncedHealth Volunteers Overseas (HVO), in collaboration with the Society for Education in Anesthesia (SEA), is pleased to announce that nine anesthesia residents have been awarded the 2011 SEA-HVO Traveling Fellowship. One of those residents is our very own Anne Cherry, MD. She will leave for either Ethiopia or South Africa in February 2012.

The SEA-HVO Fellowship allows senior anesthesia residents the opportunity to improve anesthesia care in developing countries by teaching and mentoring their counterparts. The SEA-HVO Fellows will be

challenged to learn about diseases which are rare in the United States but becoming less so with globalization. They will learn important lessons on delivering health care in a resource-scarce environment and working with health care providers in a different cultural environment. Most important, they will contribute to the future safety of patients receiving anesthesia in developing nations.

http://anesthesiology.duke.edu 1

NewsMonday, July 11, 2011 • Volume 13, Issue 26

Dr. Russell Appointed to SCCM CommitteeMichael Russell, MD has been appointed to the Society of Critical Care Medicines’ Committee on Patient and Family Support. This committee provides information and resources to patients and their families about the ICU experience, including end-of-life issues. The committee selects the recipient of the Family Centered Care Award.

“I have long felt that helping patients and their families come to terms with a highly stressful, fear invoking, and frequently terminal episode of care is a very important and often undervalued part of critical care as a subspecialty. It’s more than the technology. Based in essentially a community hospital setting as we are here at Duke Raleigh, I’m very pleased we receive high marks for patient/family satisfaction (86% positive at last survey) and I welcome the opportunity to work with critical care colleagues nationally to personalize critical care as much as possible.”

Comings and GoingsPlease welcome the following new employees to the Anesthesiology family:

Christopher Allen, Business Office, Grants & Contracts AssistantStarted: 7/11/2011

Brandon Holmes, Neuroanesthesiology, Staff AssistantStarted: 7/11/2011

We wish a fond farewell to Jay Kher, Clinical Associate who has left the department on June 30, 2011.

Leaving the department soon? Let’s keep in touch! Please contact Lauren Marcilliat at lauren.marcilliat@duke.edu with your new mailing and email address prior to your departure so that we can add you to our database!

July 10 - 16 Birthday Wishes

Catherine Dunston Kathryn NewmanJanet Goral Julie RosatoGerri Harris Dr. Michael RussellRenee Januchowski Jessie Swain IIIDavid Joseph Mark WrightHaley Meyer

Note: If you do not want your name listed here, please send a removal notice to keith010@mc.duke.edu. See errors? Please report them to the business office.

ThIs Month In the DepartMent of anesthesIology

http://anesthesiology.duke.edu 2

July 2011MonDay tUesDay WeDnesDay thUrsDay frIDay11 12 13 14 157:15-8:00 a.m., RM203-Pain ClinicMRC Pain Conference

2:30-3:30 p.m., VAMCVA EchocardiographyConference

5:30-6:30 p.m., 5680A-HAFSPerioperative Leadership Group Meeting: CANCELLED

5-6 p.m., 5685-HAFSCT Conference

IrB Deadline

7:00 a.m., 2001DNGrand Rounds: “What Can Pop Culture Teach Us About Feedback: You Don’t Have to be Cruel to be Kind” - Cath-erine Kuhn, MD

4:30 p.m., 5685-HAFSAdvanced Resident Lecture: “Physician Impairment”- Catherine Kuhn, MD

7:15-8:00 a.m., RM203-PainClinicMRC Pain Journal Club

4-5 p.m., 5680A-HAFSPediatric Conference

18 19 20 21 227:15-8:00 a.m., RM203-Pain ClinicMRC Pain Conference

2:30-3:30 p.m., VAMCVA EchocardiographyConference

5-6 p.m., 5685-HAFSCT Conference

IrB Deadline

7:00 a.m., 2001DNGrand Rounds: “Informed Refusal Pro Re Nata: Ethical Issues in Anesthesiology” - Lauren A. McQueen-Shad-far, MD

4:30 p.m., 5685-HAFSAdvanced Resident Lecture: “Neuroanesthesia Emergen-cies and Intracranial Pressure Monitoring”- David McDonagh, MD

7:15-8:00 a.m., RM203-PainClinicMRC Pain Journal Club

4-5 p.m., 5680A-HAFSPediatric Conference

5-6 p.m., 5685-HAFSEducation Committee Meeting

25 26 27 28 297:15-8:00 a.m., RM203-Pain ClinicMRC Pain Conference

2:30-3:30 p.m., VAMCVA EchocardiographyConference

5-6 p.m., 5685-HAFSCT Conference

IrB Deadline

7:00 a.m., 2001DNGrand Rounds: “Clinical Case Conference” - Jonathan Mark, MD

4:30 p.m., 5685-HAFSAdvanced Resident Lecture: “Emergencies on Cardiopul-monary Bypass”- J. Mauricio Del Rio, MD

7:15-8:00 a.m., RM203-PainClinicMRC Pain Journal Club

4-5 p.m., 5680A-HAFSPediatric Conference

Pictures  from:  Podiatry  Today,  Voly  21,  Issue  8,  August  2008,  Harriet  W.  Hopf,  Md,  Caroline  E.  Fife,  MD    

Hyperbaric  Grand  Rounds  5:00pm  July  21,  2011  Hyperbaric  

Conference  Room  Michael  Kerzner,  DPM  

Duke  Department  of  Orthopedic  Surgery  

HBO  and  the  DiabeBc  Foot  

¥  RaBonale  for  HBO  in  the  treatment  of  foot  lesions  in  diabeBc  paBents.  

¥  Which  diabeBc  paBents  may  benefit?  ¥  Place  of  HBO  in  the  mulBdisciplinary  

team  approach  for  the  DFU.  ¥  How  can  HBOT  efficacy  be  evaluated?  ¥  Is  HBOT  cost  effecBve?  

Upcoming:

2011 Duke Anesthesiology Alumni Reception Sunday, October 16, 2011, The Field Museum Chicago, IL

2011 ASA October 15-19, 2011 | McCormick Place Convention Complex, Chicago, IL

2011 Duke anesthesiology holiday party Saturday, December 3, 2011 | The Cotton Room at Golden Belt, Downtown Durham, NC

Grant Overview

The DREAM Innovation Grant (DIG) supports innovative high-risk, and potentially high-reward investigations to accelerate anesthesia and pain management research.

Research deemed innovative may introduce a new paradigm, challenge current paradigms, look at existing problems from new perspectives, or exhibit other uniquely creative qualities. The DIG promotes new ideas; therefore, proposals need not include preliminary data. However, a solid rationale for the work must be provided. Proposed work should not be the next logical step of previous work, but should have a high probability of revealing new avenues of investigation. This program aims to provide pilot funding that will lead to successful competition for additional funding beyond the pilot period. The research concept, scientific team, and explicit plans for how this work will lead to follow-on funding will be the primary criteria for judging. These points should be specifically addressed in the application.

The principal investigator (PI) is responsible for clearly and explicitly articulating the project’s innovation and the potential impact on anesthesia and pain management research.

Eligibility

All faculty members of the Department of Anesthesiology at Duke are eligible to apply. One of the grants will be reserved to support a beginning scientist (within 5 years of completion of residency or fellowship) by encouraging and adequately funding projects that can contribute to bridging the gap between training and progression to independent investigator status. The other

award(s) will be used as a seed grant to help investigators with promising science obtain preliminary data to support follow-on funding applications.

Funding

A maximum of $30,000 will be awarded to each recipient. None of the funds awarded are to pay for faculty salary or overhead expenses. The number of grant recipients and grant amount will be determined by the DREAM Innovation Grant Committee after all applications have been received. Application and Deadline

Applications and questions should be submitted to David S. Warner, M.D. at david.warner@duke.edu.

1. A Statement of Intent (Deadline July 28, 2011): a. Abstract (150 word max) b. Preliminary Budget (Budgets should not include salary support for a faculty, resident, or fellow) c. NIH formatted Biosketch

2. NIH R03-like Application Format (Deadline September 6, 2011): i.e., up to 1 page for Specific Aims and up to 6 pages for the background, preliminary data and/or rationale, experimental plan, description of roles of scientific team members, timeline for milestones and completion, and definition of plans to advance work beyond this funding interval (all pages single-spaced, 11 point Arial font). Applications should include NIH biosketches of all participants.

3. Winners will be announced October 16, 2011 during the ASA Alumni Reception.

DREAM Innovation Grant (DIG)

speCIal annoUnCeMent

http://anesthesiology.duke.edu 3

anesthesIology neWs

http://anesthesiology.duke.edu 4

ClassifiedsReal Estate/Rentals

For Sale: Large and Beautiful Kerr Lake Home with Guest House. $5000 Finders fee paid to any-one who brings us a closing buyer! 4 Bedrooms, 3 Full, 2 Half Baths. 5 garage Bays, 3 with HVAC (1 used as workshop). Large covered, floating boat dock with swim/sun platform. For more info and Pix: kjmaltais@gmail.com 252-213-1468. Visit our web-

site: http://maltaisrealestate.ning.com/

For Sale: House on Quiet Cul-de-Sac 5 minutes to Duke. 10 DuBarry Court, Durham, NC 27705 *$224,900* 3 bed-room, 2 bath in Westwood Estates on quiet cul-de-sac. Approx. 1940 sq. ft. on approx. .42 acres. Berini Built home. 3 large bedrooms, 2 bathrooms, large eat-in kitch-en, formal dining room, formal living room, entrance foyer, family room/den, fireplace with gas logs, laundry closet off

of kitchen, deck, storage shed in backyard, carport with storage room, hardwood floors throughout except kitchen and family room. Call 919-475-1780 or 919-724-0924 if you would like more information or see the house.

Merchandise

Precor Ellptical #5.31. Just like new $2,500. Normally retails for $4,000. If you are interested, please contact Jeff at 919-610-9397.

Upcoming CME Activities

4th annual UnC-Duke pediatric anesthesiology Conference“Best practices in pediatric anesthesia Care”august 27, 2011 | the William & Ida friday Center for Continuing education | Chapel Hill, NCPlease visit: http://www.med.unc.edu/cme/events/4th-annual-unc-duke-pediatric-anesthesiology-conference-best-practices-in-pediatric-anesthesia-care for more information and to register.Due to their many anatomic, physiologic, and developmental differences, infants and young children constitute a high-risk population for undergoing anesthesia and surgery. A collaborative approach requires that all team members function with the most up-to-date information on providing safe pediatric anesthesia care.

Ultrasound for every anesthesiologist Pre-ASA Workshopoctober 14, 2011 | the W hotel, lakeshore | Chicago, Ilfor more information, email Katherine siler: siler006@mc.duke.edu.This is a one-day intensive hands-on workshop specifically designed to teach ultrasound to Anesthesiologists of all skill levels ensuring that ultrasound is being used correctly and to its full potential. The use of ultrasound guided regional anesthesia could increase patient cases and success in patient outcome.

Collaborative anesthesia and obstetric Care of the high-risk Delivery: What’s new in patient safety?november 12, 2011 | rizzo Conference Center | Kenan-flagler Business School, Chapel Hill, NCfor more information, email Bridget White: bridget.white@duke.edu.This one-day course will focus on the obstetric and anesthetic considerations and preparations for the management of high-risk parturients.

Ultrasound Guided Regional Anesthesia preceptorship Course2011 Dates Available | Duke University Medical Center, Durham, NCfor more information, email Katherine siler: siler006@mc.duke.edu.Participants in the Duke Preceptorship will spend three days in the regional block area, operating rooms and on the floor with post surgery patients observing ultra-sound guided single shot nerve blocks and catheter techniques in a wide variety of clinical scenarios. They will learn how to set up the block area for maximum efficiency in the OR environment, improve their decision making ability and make choices in the performance of regional anesthesia. A one-on-one discussion with the Duke Faculty member reviewing cases, scanning techniques and the image library as well as covering handout materials will augment the preceptorship experience.

Visiting preceptorship in Intraoperative Transesophageal Echocardiography2011-2012 Dates Available | Duke University Medical Center, Durham, NCfor more information, email Jaime C. Cooke: jca24@notes.duke.edu.Participants in the Duke Intraoperative TEE Preceptorship spend one three-day session in the cardiac operating suites, observing techniques of intraoperative TEE and interpretation of images. Preceptors will participate in active discus-sions with cardiothoracic anesthesia faculty and fellows, and learn the basic TEE exam. They will also learn how to troubleshoot difficult cases and enhance their decision-making skills in the operating room. Cases will be reviewed with fellows and faculty and images from pathology libraries will be used to augment the preceptorship experience.

New Future Anesthesiologists!Andrew and Anne Peery had a son, John Ethan Peery, on June 28, 2011. Everyone is doing great.

heartfelt thanks!Many thanks to my friends and colleagues for all the technical skills, good wishes, worrying, and prayers during my recent mitral valve re-pair. Everything went well, and recovery is as good as expected, although still in process. It is great to know so many resources were applied and available if needed. See you all fairly soon. - Ron Olson, MD

CondolencesCondolences to Wendy Dixon and family. Her brother, Ken Carthen passed away on Saturday, July 2, 2011. Our thoughts and prayers are with you during this difficult time.