1 uiuc bioengineering bruce c. wheeler, bioengineering for current uiuc undergrads, september 2005...

Bruce C. Wheeler, Bioengineering for Current UIUC Undergrads, September 2005

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UIUC BioEngineeringUIUC BioEngineering

WHAT IS BIOENGINEERING?

Bruce C. Wheeler, Interim HeadBioengineering Department

University of Illinoisat Urbana-Champaign


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Bioengineering is Exceptionally Diverse

While viewing the next dozen slides, try to identify the kinds of knowledge needed to work on the projects.

You should conclude that no one is able to learn more than a fraction of what is called bioengineering.

Consequently, you should be aware of this breadth, but focus on the area of greatest interest to you.


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What is Bioengineering?

Any Area of Biology Mixed with

Any Area of EngineeringIn

Any Proportion


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Example: Magnetic Resonance Imaging

– Electrical Engineers: electromagnetics– Computer Engineers/Scientists: computation– Physiologists: biological function– Chemists: new imaging agents– Psychologists: mental function– Physicians: medical implications


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More Bioengineering ExamplesArtificial Skin

– Materials Scientist: artificial polymers– Cell Biologist: tissue reaction

EKG Machine– Engineers: electronics– CS: automated diagnosis– Physician: medical design

Pharmaceutical Production– Molecular Biologist: receptor / ligand identification– Genetic Engineer: induce bacteria to produce molecules– Chemical Engineer: scaleup of production


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Examples of Engineers in Medicine and Biology

• Materials Science: Implants (e.g. artificial hip) • Electrical Engineering: Cardiac Signals• Computer Science: computer data bases, programs,

bioinformatics• Computer Engineering: computer design for CAT

scanners• Physics: basics of Magnetic Resonance Imaging


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Examples of Engineers in Medicine and Biology

• Chemical Engineering: Pharmaceuticals• Mechanical Engineering: Rehabilitation Devices• Nuclear Engineering: Radiology• Civil Engineering: Environmental problems• Agricultural Engineering: Food Processing


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Areas Emerging in“Engineering of Biology”

– Bioinformatics (Genetic / Proteomic Data Base, Design, Inquiry)

– BioMolecular Modeling– Genetic Engineering of Animals– Genetic Engineering of Proteins, Drugs– Cell and Tissue Engineering– Neural Engineering– Biomaterials


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Programs Related to Bioengineering

• Environmental Engineering– Sponsored by the Dept. of Civil and Environmental

Engineering (http://cee.ce.uiuc.edu/)

– Includes water, soil, air quality control and protection

• Agricultural and Biological Engineering– Sponsored by the Dept. of Agricultural and Biological

Engineering (http://www.age.uiuc.edu/)

– Includes food processing, farm and indoor environmental control


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More Programs Related to Bioengineering

• Nuclear, Plasma, and Radiological Engineering Department and Degree Program

• Biomaterials concentration in Materials Science and Engineering

• Chemical and Biomolecular Engineering Department and Degree Program


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What Do I Need to Study to be a Bioengineer?

• Short Answer #1: Everything

• Short Answer #2: Depends-- on what interests you most


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What Do I Need to Study?• Mathematics

– Calculus through Differential Equations

• Physics (calculus based)– Mechanics, Electromagnetics, Modern Physics

• Chemistry– Through Organic and Biochemistry

• Biology– Strong in Molecular Biology, but also Cellular and

Systems Physiology


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What Do I Need to Study?Traditional Approaches #1 and #2

• Choose one major and one minor from traditional disciplines:– 1. Engineering Side: Electrical Engineering,

Mechanical, Chemical, Materials, Nuclear, Computer Science …

– 2. Life Science Side: Molecular and Cellular Biology, Physiology, Cell Biology, Microbiology …

• Anticipate possible need for one more year to double major to achieve career objectives


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Major in the area you like better ...• "If you could be either an engineer or a biologist, but

not both, which would it be?"– Major in that field ... and minor in the other.– Yes, you can go to Biomed. Eng. grad school from either

the Life Sciences or Engineering– … but not if you do not have the basics … calculus,

physics, chem, biochem, at least some beginning engineering coursework and some beginning life science coursework


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Approach #3: Bioengineering DegreeUIUC for the Class of 2008, 2009

• Math, physics, chemistry, biology core, CS• Bioengineering Core:

– Instrumentation/circuits, biomaterials, biomechanics

• Concentration in one of:– Engineering discipline: EE, ME, …– Life science discipline: Physiology, Cell Biology …– Topical area: microsensors, bioinformatics, tissue

engineering, …

• Anticipate possible need for an extra year to receive the MS degree to achieve career objectives


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Why the Extra Year of Study?

• There’s too much to learn in four years• Four years will prepare you for:

– Graduate school– Medical school (if courses are well-chosen)– Engineering in a traditional major, including applications

in biomedical area– Life science positions, including applications with

significant engineering components

• But not for:– Bioengineering positions in which advanced knowledge

in both life science and engineering are required


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General Recommendations

• Essential Preparation Includes:– Science Fundamentals: Chem, Biol, Physics, Math

– Academic Concentration: a major in an engineering discipline or in Molecular and Cellular Biology

– Enthusiasm: junior / senior research project

• Existing majors will launch students into bioengineering careers, medical or graduate school


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What Can Traditional Engineering Students Study in the Bioengineering Related Areas?

Major in: MatSE (biomaterials concentration), NucE (radiology curriculum), ChemE (molecular biology option coming soon), EE (lots of BioE/ECE electives), Gen Eng (BioE secondary field), CS (application sequences in Bio, Biochem), ME, Aero, TAM ...

Minor in Bioengineering (21 hrs)


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Notes for Engineering Students who want to study Bioengineering

• Don’t forget to take enough Chemistry• If you have AP credit for Chem 102/103, talk to the

Chemistry advisors about lab experiences and how best to prepare for Organic Chem and Biochem

• AP Biology Credit does not cover the minor but it is better preparation than having taken nothing

• MCB 103 (Human Physiology) and MCB 150 are good courses to find out if you like biology enough to pursue bioengineering

• Look at what the MCB students take to understand how much biology you need


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Medical School for Engineers

• Yes, many Engineers do so. Acceptance rates are good, but medical school is very competitive.

• If you only want to go to med school, choose LAS Biology.

• Premeds dominate Bioengineering Degree Programs across the U.S.

• See the Career Services Office Immediately to Plan your Courses, Volunteering, Etc.


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What Can LAS Life Science Students Study in Bioengineering Related Areas?

Major in Molecular and Cellular Biology (MCB) Emphasis in Bioinformatics

– Calculus, Physics, Chem (thru Biochem)– Biology (16 hours; molecular bio emphasis)– Computation/Modeling electives (9)

Consult with Life Science Advising Office About Ways to Tailor your Coursework toward Bioengineering

Other emphases: cell & develop. biology, physiology, biophysics, microbiologyFor students who entered in 2000 or earlier:

Bioengineering Option in Life Sciences curriculum

http://www.life.uiuc.edu/mcb/undergraduate/index.html


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Notes for LAS Life Science Students Who Wish to Pursue Bioengineering

• Take calculus based physics – 211/212/213/214

• An incomplete list of engineering related courses you should consider taking:

• BIOE related: BIOE 414/415 Bioinstrumentation; BIOE 475, 417 Neural Modeling; BIOE 280/480 Medical Imaging, MRI; BIOE 471 Biomaterials; BIOE 406 Biomechanics; CHBE 472/473 Biomolecular Engr;

• Engineering Basics: ECE 205/6 Circuits/Lab; ECE 473/474 Acoustics/Ultrasonics; CS 101/110/125/225/257/400/411 beginning thru data bases and numerical techniques; PHYS 404/405 Electronic Circuits; TAM 210/211/212 Mechanics fundamentals; MSE 280 Intro to Materials

• Remember that most BS Bioengineering degree students take at least 30 hours of engineering courses beyond physics, calculus, chem


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Suggestions for MCB Students

• Consider Bioinformatics/Computational Biology or Biophysics Emphasis (approx. 75 hours)

• Take calculus based Physics (211,212,213,214) and calculus through Dif Eq (220,230,242,385)

• General Education: 25 hours additional• Remaining: 20 to 30 hours for electives including

building a bioengineering concentration• Take CS 101 and CS 400 (7 hrs; non-CS majors)• For reference: Min Hours to Graduate: LAS 120;

Engrg 128 (typical).


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Suggestions for New MCB Students: Focused Use of Electives Minor in Engineering

(an unauthorized proposal)

Prerequisites:Math 220/230/242/385Physics 211/212/213/214Chem 102/103/104/105

Courses for the Minor:ECE 205/206 Electronic CircuitsCS 101, 400 Programming, Data StructuresTAM 210, 212 Statics & DynamicsME 300 or MATSE 401 ThermodynamicsMATSE 280 Intro Materials


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Suggestions for MCB Students: Focused Use of Electives ECE/BioEn Emphasis

Take as many as possible …• ECE 205 (3 hrs; Circuits), GE 320 (4 hrs; Control

Systems)• BioEn 414/415 (3/2 hrs; Bioinstrumentation & Lab)• ECE 473 (3 hrs; Acoustics)• ECE 475 (3 hrs; Modeling Biological Systems)

• Total: 18 hours


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Suggestions for MCB Students: Focused Use of Electives MechE/BioEn Emphasis

Take as many as possible …• TAM 211/212/251 (3/3/3 hrs; Statics/Dynamics/

Solid Mechanics)• ME 498 EH1 (3 hrs; Modeling of Musculoskeletal

Biomechanics)• Bioen 406 (3 hrs; Orthopedic Biomechanics)• Bioen 461 (4 hrs; Cellular Biomechanics)• Bioen 471 (3 hrs; Biomaterials)

• Total: 22 hours


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Suggestions for MCB Students: Focused Use of Electives Biomaterials Emphasis

Take as many as possible …• MatSE 201/206 (3/4 hrs; Phase Relations/ Mechanics)• MatSE 401/406 (4/3 hrs; Thermodynamics)• MatSE 470/472 (3/1 hrs; Design of Biomaterials / Lab)• MatSE 473 (3 hrs; Biomolecular Mat. Sci.)

• Total: 21 hours


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Suggestions for MCB Students: Focused Use of Electives

Life Science Emphases

Take as many as possible …

• Choose additional courses from the Emphases in Physiology, Cell & Structural Biology or Microbiology

Engineering or Computer Science EmphasesPick an Existing Engineering Major• Take as many as possible of the courses in that major – typically

you will be able to take sophomore and junior level courses


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For more information

Bioengineering Student Society

EMBS = Engineering in Medicine and Biology

-- get on the Email List Today!

Bioengineering Office3120 DCL1304 W. Springfield Urbana IL [email protected]

1 uiuc bioengineering bruce c. wheeler, bioengineering for current uiuc undergrads, september 2005...

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