14. hospital infections and isolation nursing part ii

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    Important NosocomialImportant Nosocomial

    InfectionsInfectionsManagement of InfectiousManagement of Infectious

    PatientsPatients

    Chapters 13 and 14 ofChapters 13 and 14 of

    your textbookyour textbook

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    Aseptic TechniqueAseptic Technique

    Prevent introduction of microorganismsPrevent introduction of microorganismsinto sites during treatment orinto sites during treatment or

    manipulationmanipulationUse for wound dressing, IV lines,Use for wound dressing, IV lines,

    catheters, suturing, vaginal examination,catheters, suturing, vaginal examination,invasive proceduresinvasive procedures

    Wear gloves, use sterile packWear gloves, use sterile pack

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    Wound InfectionWound Infection

    Look for signs of infection regularlyLook for signs of infection regularly

    Risks:Risks:

    Site of woundSite of woundPatient susceptibilityPatient susceptibility

    Presence of foreign materialPresence of foreign material

    PrePre--operative stayoperative stay

    Duration of operationDuration of operationSurgical skillSurgical skill

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    Check records of surgicalCheck records of surgicalinfectioninfection -- note thenote the

    surgeon. Is anyonesurgeon. Is anyonegetting more infectedgetting more infectedpatients than average?patients than average?

    Inform the surgeonsInform the surgeonswith poor records ofwith poor records oftheir statustheir status -- oftenoftenresults in improvement!results in improvement!

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    Prevention of Wound InfectionPrevention of Wound Infection

    Preparation of patientPreparation of patientHealthy if possibleHealthy if possible

    Preoperation showerPreoperation showerClean skin with disinfectant before surgeryClean skin with disinfectant before surgery

    Shave immediately before surgeryShave immediately before surgery

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    Prevention of Wound InfectionPrevention of Wound Infection

    Hand washingHand washingSurgical scrubSurgical scrub removes resident andremoves resident and

    transient organismstransient organismsChlorhexidine or povidoneChlorhexidine or povidone--iodineiodine

    TheatreTheatreClean airClean air

    Protective clothingProtective clothing

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    Prevention of Wound InfectionPrevention of Wound Infection

    PostPost--operative careoperative careFirst 24 hours most importantFirst 24 hours most important

    Inspect regularly for signs of infectionInspect regularly for signs of infectionAntiseptics may not be usefulAntiseptics may not be useful

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    Chronic woundsChronic wounds

    Clean gloves and apronsClean gloves and aprons

    Prevent crossPrevent cross--infectioninfection

    Creams etc for one patient onlyCreams etc for one patient onlyBurns especially at risk of infectionBurns especially at risk of infection

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    Bloodstream InfectionBloodstream Infection

    6% of HAI6% of HAI mostly in ICUmostly in ICU

    SepticaemiaSepticaemia symptomssymptoms

    BacteraemiaBacteraemia no symptomsno symptomsFrom IV devicesFrom IV devices oror infectionsinfections

    elsewhere in the bodyelsewhere in the body

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    IV device infectionIV device infection

    RisksRisks MultiMulti--lumen lineslumen lines

    SiteSite (femoral vein for central venous(femoral vein for central venous

    catheters?? x) Subclavian catheters?? x) Subclavian DurationDuration

    Pressure monitoringPressure monitoring

    Cannula materialCannula material impregnated materialsimpregnated materials Implantable devicesImplantable devices--lower rate infectionlower rate infection

    Smooth surface-TeflonAntiseptic/antibiotics

    Staphylococcus epidermidis!!Can (a) adhere to catheters and (b) produce

    slime

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    IV device infectionIV device infection

    Prevention Catheter Insertion asepsis, protective clothing, skin

    preparation, firm anchoring of the catheter

    Maintenance of site polyurethane dressings to cover

    insertion site Management of fluid administration equipment

    reduce manipulation, change sets every 72 hours or ifused for blood or lipid emulsion, parenteral feeding

    should have designated tube Catheter Replacement remove and resite peripheral

    lines every 72 hours, do not move central lines

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    Urinary Tract InfectionUrinary Tract Infection

    Most common form of HAI (20% of allMost common form of HAI (20% of allHAI)HAI)

    Mostly linked to catheter useMostly linked to catheter use1010 --30% develop infection30% develop infection

    One third of infected patients haveOne third of infected patients have

    symptoms including fever and painsymptoms including fever and painUncomplicated infections can be easilyUncomplicated infections can be easily

    treatedtreated

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    Urinary Tract InfectionUrinary Tract Infection

    Long term catheterisationLong term catheterisation

    Repeated infection, spread to kidney,Repeated infection, spread to kidney,

    urinary stones.urinary stones.Risk of bacteraemia and septicaemiaRisk of bacteraemia and septicaemia

    can be fatalcan be fatal Gram negativeGram negative

    septicaemiasepticaemia

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    Urinary Tract InfectionUrinary Tract Infection

    Symptoms and DiagnosisSymptoms and DiagnosisEcoli, Pseudomonas, ProteusEcoli, Pseudomonas, Proteus

    Often no symptoms in catheterisedOften no symptoms in catheterisedpatientspatients

    Suspect UTI if patient is pyrexicSuspect UTI if patient is pyrexic

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    Role of the CatheterRole of the Catheter

    Enables bacteria from perineum to reachEnables bacteria from perineum to reachbladderbladder

    Organisms enter system when bag isOrganisms enter system when bag isemptiedemptied

    Risk of infection increases with timeRisk of infection increases with time byby30 days almost all infected30 days almost all infected

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    Preventing UTI infectionPreventing UTI infection

    InsertionInsertionUseUse anaestheticanaesthetic gel togel to meatusmeatus

    Carefully position patientCarefully position patientAvoid touchingAvoid touching periurethralperiurethral

    areaarea

    Aseptic technique!Hand hygiene!

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    Choose 10 ml balloon, narrow lumenChoose 10 ml balloon, narrow lumenunless urine has a lot of debrisunless urine has a lot of debris

    SiliconeSilicone resistant to biofilm build upresistant to biofilm build up good for long term catheterisationgood for long term catheterisation

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    Preventing UTI infectionPreventing UTI infection

    RemovalRemovalRemove as soon as possibleRemove as soon as possible

    Only change if encrustedOnly change if encrustedUse of disinfectants around meatus do notUse of disinfectants around meatus do not

    appear to reduce infectionappear to reduce infection

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    Preventing UTI infectionPreventing UTI infection

    Avoid disconnection of catheter and bagAvoid disconnection of catheter and bag

    Prevent kink in the tubePrevent kink in the tube refluxreflux

    Encourage high fluid intakeEncourage high fluid intake-- lemon andlemon andcranberry drinkscranberry drinks

    Aseptic handling of catheterAseptic handling of catheter

    Always use gloves to handle catheter andAlways use gloves to handle catheter andwash hands afterwash hands after

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    UTIUTI -- Use ofCathetersUse ofCatheters

    Treatment of UTI in Catheterised patientsTreatment of UTI in Catheterised patients

    Only treat asymptomatic patients with catheterOnly treat asymptomatic patients with catheteron removalon removal -- just exchange sensitive forjust exchange sensitive forresistant strainsresistant strains

    Treat symptomatic infectionsTreat symptomatic infections

    Encouragesantibioticresistance

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    LowerRespiratory InfectionLowerRespiratory Infection

    Serious LifeSerious Life--threateningthreatening

    Important type of HAIImportant type of HAI

    Gram negative organismsGram negative organisms KlebsiellaKlebsiellapneumoniaepneumoniae

    High mortality rateHigh mortality rate

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    LowerRespiratory InfectionLowerRespiratory Infection

    Risk FactorsRisk Factors Inhalation of airborne particlesInhalation of airborne particles

    Aspiration of material from oropharynxAspiration of material from oropharynx

    Increased risk if oropharynx colonised by GramIncreased risk if oropharynx colonised by Gramnegative organismsnegative organisms

    Age, illness, immunosuppressionAge, illness, immunosuppression

    Antibiotics, surgery, nasogastric tubes,Antibiotics, surgery, nasogastric tubes,

    endotracheal tubeendotracheal tube Supine position, unconsciousness,Supine position, unconsciousness,

    AerosolsAerosols nebulisers, ventilatorsnebulisers, ventilators

    Narcotics for pain reliefNarcotics for pain relief

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    Supine

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    LowerRespiratory InfectionLowerRespiratory Infection

    Colonisation of oropharynx and stomachColonisation of oropharynx and stomach

    Depletion of fibronectin allows colonisationDepletion of fibronectin allows colonisation occurs in severe illnessoccurs in severe illness

    Occurs in postOccurs in post--surgical patientssurgical patients

    Tubes enhance colonisation and aspirationTubes enhance colonisation and aspiration

    Stomach colonised if antacids given to preventStomach colonised if antacids given to prevent

    stress bleeding, also old age, gastro disease andstress bleeding, also old age, gastro disease andenteral feedsenteral feeds -- refluxreflux

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    LowerRespiratory InfectionLowerRespiratory Infection

    VentilationVentilation Risk increase daily by 1%Risk increase daily by 1%

    Biofilm on tubeBiofilm on tube

    ContaminatedContaminatedaerosolsaerosols

    NebulisersNebulisers for drugsfor drugs increase colonisationincrease colonisation

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    Prevention ofLRTIPrevention ofLRTI

    Handwashing / alcohol rub if touching ventilatorHandwashing / alcohol rub if touching ventilatortubingtubing

    Clean gloves for contact with mucousClean gloves for contact with mucous

    membranesmembranes

    Drain humidifier reservoirs and wash withDrain humidifier reservoirs and wash withdetergent, dry and refill every 48 hoursdetergent, dry and refill every 48 hours

    Use filters with resuscitation bagsUse filters with resuscitation bags Decontaminate if possible between patientsDecontaminate if possible between patients

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    Prevention ofLRTIPrevention ofLRTI

    Tracheal and endotrachealTracheal and endotrachealtubes can introduce organismstubes can introduce organismsand accumulate bacteria inand accumulate bacteria in

    biofilmsbiofilms Regular suctioning ofRegular suctioning of

    secretionssecretions

    Decontaminate suctionDecontaminate suctionequipmentequipment

    Use suction catheter once onlyUse suction catheter once only

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    Prevention ofLRTIPrevention ofLRTI

    NebulisersNebulisers wash and dry after eachwash and dry after eachuseuse

    Only use sterile solutionsOnly use sterile solutions

    Oxygen delivery equipmentOxygen delivery equipment change tubing, prongs and masks afterchange tubing, prongs and masks afterevery patientevery patient

    Enteral feedingEnteral feeding position patient toposition patient toprevent aspiration; prepare freshlyprevent aspiration; prepare freshly

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    Enteral feed

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    Prevention ofLRTIPrevention ofLRTI

    PostPost--operative measures to preventoperative measures to preventpneumoniapneumonia

    Breathing exercisesBreathing exercises

    Pain controlPain control

    Support of abdominal wounds to enable patientSupport of abdominal wounds to enable patientto cough up secretionsto cough up secretions

    Prophylactic antibiotic does not reduce incidenceProphylactic antibiotic does not reduce incidenceof infectionof infection

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    Other Hospital AcquiredOther Hospital Acquired

    PneumoniaPneumonia

    Respiratory VirusesRespiratory Viruses RSVRSV mainly children, prevent spread ofmainly children, prevent spread of

    infection by isolation, gloves aprons,infection by isolation, gloves aprons,

    handwashinghandwashing InfluenzaInfluenza young, elderly immunocompromised,young, elderly immunocompromised,

    isolate, vaccineisolate, vaccine

    SARSSARS patients with underlying illness havepatients with underlying illness have

    highest mortality, isolation, strict droplethighest mortality, isolation, strict dropletprecautionsprecautions

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    Other Hospital AcquiredOther Hospital Acquired

    PneumoniaPneumoniaegionnaires DiseaseLegionnaires Disease

    Legionella pneumophilaLegionella pneumophila

    Infection from aerosolsInfection from aerosols

    Cooling water from air conditioners, hot waterCooling water from air conditioners, hot watersystems, humidifiers, nebuliserssystems, humidifiers, nebulisers regular cleaningregular cleaningand disinfection, hot water above 50Cand disinfection, hot water above 50C

    Elderly and imunocompromisedElderly and imunocompromised

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    Other Hospital AcquiredOther Hospital Acquired

    PneumoniaPneumonia

    AspergillosisAspergillosisFungus in soil water andFungus in soil water and

    decaying vegetablesdecaying vegetablesSpores in airSpores in air

    Immunocompromised, cystic fibrosis, boneImmunocompromised, cystic fibrosis, bone

    marrow transplantsmarrow transplantsFilter airFilter air

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    AspergillisAspergillis

    Spores

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    Isolation NursingIsolation Nursing

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    IsolationIsolation

    Segregation of patients with infectiousSegregation of patients with infectiousdisease goes back thousands of yearsdisease goes back thousands of years

    Isolation aims to prevent spread ofIsolation aims to prevent spread ofinfectious disease and nosocomialinfectious disease and nosocomialpathogenspathogens

    Required when routine control cannotRequired when routine control cannotprevent spreadprevent spread

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    HistoryHistory

    Barrier nursingBarrier nursing

    1920s sterile conditions1920s sterile conditions

    1970s different isolation procedures for1970s different isolation procedures fordifferent infectionsdifferent infections too complicated!too complicated!

    1990s simplified1990s simplified one basic set of rulesone basic set of rules

    with some extras for specific infectionswith some extras for specific infections

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    PrinciplesPrinciples

    Prevent microorganisms being transmittedPrevent microorganisms being transmittedfrom infected or colonised patients to othersfrom infected or colonised patients to others

    Interrupt spread of infectionInterrupt spread of infection break chainbreak chainof transmissionof transmission

    Disturbing for patientDisturbing for patient use reasonableuse reasonable

    precautions and as short a period asprecautions and as short a period aspossiblepossible

    Consult Infection Control TeamConsult Infection Control Team

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    Points to considerPoints to consider

    OrganismOrganism Body site of infectionBody site of infection Transmission routeTransmission route

    Are other patients / staff vulnerable?Are other patients / staff vulnerable? How can the infection be controlled?How can the infection be controlled? Consider state of the patientConsider state of the patientOften too lateOften too late use for unknown rashes oruse for unknown rashes or

    pyrexiapyrexia Use for reUse for re--admissions with MRSAadmissions with MRSA

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    Transmission of InfectionTransmission of Infection

    In the hospital, three routes important:In the hospital, three routes important:

    ContactContact

    directdirect indirectindirect

    DropletDroplet

    AirborneAirborne

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    Contact TransmissionContact Transmission

    Most frequent routeMost frequent route

    DirectDirect -- organisms transferred by bodilyorganisms transferred by bodily

    contact between infected and uninfectedcontact between infected and uninfectedperson e.g. during bathing or turning aperson e.g. during bathing or turning apatientpatient

    IndirectIndirect -- contaminated instruments orcontaminated instruments orhandshands

    Prevent byPrevent by: handwashing, gloves: handwashing, gloves

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    Droplet TransmissionDroplet Transmission

    Respiratory secretions of patient expelledRespiratory secretions of patient expelledinto air by sneezing, coughing etc.into air by sneezing, coughing etc.

    Droplets propelled up to 1 metreDroplets propelled up to 1 metre

    May land on upper respiratory tractMay land on upper respiratory tractmucosa or conjunctiva of susceptible hostmucosa or conjunctiva of susceptible host----> infection> infection

    Prevent byPrevent by: use of masks: use of masks

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    Airborne TransmissionAirborne Transmission

    Spread of small dried particles of dust orSpread of small dried particles of dust ordroplet nuclei containing infectiousdroplet nuclei containing infectiousmicroorganismsmicroorganisms

    Can stay in the air for a long time and beCan stay in the air for a long time and bewidely dispersed on air currentswidely dispersed on air currents

    Can be inhaled and reach the lungsCan be inhaled and reach the lungs

    Prevent byPrevent by: good ventilation systems,: good ventilation systems,single room, protective clothingsingle room, protective clothing

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    TransmissionTransmission--basedbased

    precautio

    nsprecautio

    ns

    Additional to standard precautionsAdditional to standard precautions

    Used when patients have highlyUsed when patients have highlytransmissible or epidemiologicallytransmissible or epidemiologicallyimportant pathogensimportant pathogens

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    IsolationIsolation -- STRICTSTRICT

    Separate room, gowns, gloves, masks,Separate room, gowns, gloves, masks,glovesgloves

    Strict hand washingStrict hand washingOwn instrumentsOwn instruments

    Dressings incinerated, linen doubleDressings incinerated, linen double--baggedbagged

    May need to change gloves etc if severalMay need to change gloves etc if severalprocedures carried out on same patientprocedures carried out on same patient

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    IsolationIsolation -- STRICTSTRICT

    Private RoomPrivate Room

    For patients who contaminate theFor patients who contaminate the

    environment or cannot maintain hygieneenvironment or cannot maintain hygieneOnly relevant if patient is only source ofOnly relevant if patient is only source of

    organism in areaorganism in area

    Profuse diarrhoea and vomiting, MRSAProfuse diarrhoea and vomiting, MRSA

    Infected burns, congenital rubella, neonatalInfected burns, congenital rubella, neonatalHerpes, major skin infection, Varicella,Herpes, major skin infection, Varicella,Staphylococcal pneumoniaStaphylococcal pneumonia

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    Airborne PrecautionsAirborne Precautions

    Prevents transmission of organisms byPrevents transmission of organisms bydroplet nuclei or dustdroplet nuclei or dust

    Private room or cohortingPrivate room or cohortingSpecial ventilationSpecial ventilation negative pressurenegative pressure

    Mask, limited visitorsMask, limited visitors

    Use mask for patient if movedUse mask for patient if movedMeasles, T.B., chickenpox, SARSMeasles, T.B., chickenpox, SARS

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    Droplet PrecautionsDroplet Precautions

    Prevents transmission of organisms byPrevents transmission of organisms bydroplets that are coughed into thedroplets that are coughed into theenvironmentenvironment

    Private room or cohortingPrivate room or cohorting

    Mask within 1 metreMask within 1 metre

    Limit movement of patientLimit movement of patient

    Patient wears mask if moved out of roomPatient wears mask if moved out of room

    Pneumonia, pertussis, meningococcus,Pneumonia, pertussis, meningococcus,mumps, rubella, influenzamumps, rubella, influenza

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    Contact PrecautionsContact Precautions

    For patients with infections spreadFor patients with infections spreadby direct or indirect skin contactby direct or indirect skin contact

    P

    rivate room or cohortingP

    rivate room or cohortingGloves, gownGloves, gown

    Limiting movement of patientLimiting movement of patient

    Avoid sharing of equipmentAvoid sharing of equipmentRubella, varicella, diarrhoea, Herpes,Rubella, varicella, diarrhoea, Herpes,skin or wound infectionskin or wound infection

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    TransportTransport

    Reduce movement of isolated patients toReduce movement of isolated patients toother areas of the hospitalother areas of the hospital

    If necessary to transport cover infectedIf necessary to transport cover infected

    lesionslesionsWear mask for airborne infectionWear mask for airborne infection

    Inform mortuary if a patient has died ofInform mortuary if a patient has died of

    tuberculosis, bloodborne virus ortuberculosis, bloodborne virus orCreutzfeldtCreutzfeldt--Jacob diseaseJacob disease

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    VisitorsVisitors

    Wash hands before leaving roomWash hands before leaving room

    Restrict visitors for airborne infectionsRestrict visitors for airborne infections

    Remember isolation is stressful for theRemember isolation is stressful for thepatientpatient may have behavioural problemsmay have behavioural problems

    Inform/explain to patient and family soInform/explain to patient and family so

    that they can be preparedthat they can be preparedDo not prolong for longer than necessaryDo not prolong for longer than necessary

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    IsolationIsolation -- PROTECTIVEPROTECTIVE

    Uninfected burns, severe immuneUninfected burns, severe immunedeficiency other than AIDS, radiation ordeficiency other than AIDS, radiation or

    chemotherapy, leukaemia, severechemotherapy, leukaemia, severedermatitisdermatitis

    However most infections from own floraHowever most infections from own flora

    Private room, filtered airPrivate room, filtered airMask, gowns, gloves, strict handwashingMask, gowns, gloves, strict handwashing

    Staff/visitors with RTI should stay awayStaff/visitors with RTI should stay away

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    IsolationIsolation -- PROTECTIVEPROTECTIVE

    Low bacteria diet, thoroughly cook meat,Low bacteria diet, thoroughly cook meat,wash fruit/veg & peeledwash fruit/veg & peeled