14. hospital infections and isolation nursing part ii
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Important NosocomialImportant Nosocomial
InfectionsInfectionsManagement of InfectiousManagement of Infectious
PatientsPatients
Chapters 13 and 14 ofChapters 13 and 14 of
your textbookyour textbook
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Aseptic TechniqueAseptic Technique
Prevent introduction of microorganismsPrevent introduction of microorganismsinto sites during treatment orinto sites during treatment or
manipulationmanipulationUse for wound dressing, IV lines,Use for wound dressing, IV lines,
catheters, suturing, vaginal examination,catheters, suturing, vaginal examination,invasive proceduresinvasive procedures
Wear gloves, use sterile packWear gloves, use sterile pack
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Wound InfectionWound Infection
Look for signs of infection regularlyLook for signs of infection regularly
Risks:Risks:
Site of woundSite of woundPatient susceptibilityPatient susceptibility
Presence of foreign materialPresence of foreign material
PrePre--operative stayoperative stay
Duration of operationDuration of operationSurgical skillSurgical skill
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Check records of surgicalCheck records of surgicalinfectioninfection -- note thenote the
surgeon. Is anyonesurgeon. Is anyonegetting more infectedgetting more infectedpatients than average?patients than average?
Inform the surgeonsInform the surgeonswith poor records ofwith poor records oftheir statustheir status -- oftenoftenresults in improvement!results in improvement!
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Prevention of Wound InfectionPrevention of Wound Infection
Preparation of patientPreparation of patientHealthy if possibleHealthy if possible
Preoperation showerPreoperation showerClean skin with disinfectant before surgeryClean skin with disinfectant before surgery
Shave immediately before surgeryShave immediately before surgery
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Prevention of Wound InfectionPrevention of Wound Infection
Hand washingHand washingSurgical scrubSurgical scrub removes resident andremoves resident and
transient organismstransient organismsChlorhexidine or povidoneChlorhexidine or povidone--iodineiodine
TheatreTheatreClean airClean air
Protective clothingProtective clothing
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Prevention of Wound InfectionPrevention of Wound Infection
PostPost--operative careoperative careFirst 24 hours most importantFirst 24 hours most important
Inspect regularly for signs of infectionInspect regularly for signs of infectionAntiseptics may not be usefulAntiseptics may not be useful
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Chronic woundsChronic wounds
Clean gloves and apronsClean gloves and aprons
Prevent crossPrevent cross--infectioninfection
Creams etc for one patient onlyCreams etc for one patient onlyBurns especially at risk of infectionBurns especially at risk of infection
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Bloodstream InfectionBloodstream Infection
6% of HAI6% of HAI mostly in ICUmostly in ICU
SepticaemiaSepticaemia symptomssymptoms
BacteraemiaBacteraemia no symptomsno symptomsFrom IV devicesFrom IV devices oror infectionsinfections
elsewhere in the bodyelsewhere in the body
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IV device infectionIV device infection
RisksRisks MultiMulti--lumen lineslumen lines
SiteSite (femoral vein for central venous(femoral vein for central venous
catheters?? x) Subclavian catheters?? x) Subclavian DurationDuration
Pressure monitoringPressure monitoring
Cannula materialCannula material impregnated materialsimpregnated materials Implantable devicesImplantable devices--lower rate infectionlower rate infection
Smooth surface-TeflonAntiseptic/antibiotics
Staphylococcus epidermidis!!Can (a) adhere to catheters and (b) produce
slime
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IV device infectionIV device infection
Prevention Catheter Insertion asepsis, protective clothing, skin
preparation, firm anchoring of the catheter
Maintenance of site polyurethane dressings to cover
insertion site Management of fluid administration equipment
reduce manipulation, change sets every 72 hours or ifused for blood or lipid emulsion, parenteral feeding
should have designated tube Catheter Replacement remove and resite peripheral
lines every 72 hours, do not move central lines
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Urinary Tract InfectionUrinary Tract Infection
Most common form of HAI (20% of allMost common form of HAI (20% of allHAI)HAI)
Mostly linked to catheter useMostly linked to catheter use1010 --30% develop infection30% develop infection
One third of infected patients haveOne third of infected patients have
symptoms including fever and painsymptoms including fever and painUncomplicated infections can be easilyUncomplicated infections can be easily
treatedtreated
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Urinary Tract InfectionUrinary Tract Infection
Long term catheterisationLong term catheterisation
Repeated infection, spread to kidney,Repeated infection, spread to kidney,
urinary stones.urinary stones.Risk of bacteraemia and septicaemiaRisk of bacteraemia and septicaemia
can be fatalcan be fatal Gram negativeGram negative
septicaemiasepticaemia
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Urinary Tract InfectionUrinary Tract Infection
Symptoms and DiagnosisSymptoms and DiagnosisEcoli, Pseudomonas, ProteusEcoli, Pseudomonas, Proteus
Often no symptoms in catheterisedOften no symptoms in catheterisedpatientspatients
Suspect UTI if patient is pyrexicSuspect UTI if patient is pyrexic
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Role of the CatheterRole of the Catheter
Enables bacteria from perineum to reachEnables bacteria from perineum to reachbladderbladder
Organisms enter system when bag isOrganisms enter system when bag isemptiedemptied
Risk of infection increases with timeRisk of infection increases with time byby30 days almost all infected30 days almost all infected
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Preventing UTI infectionPreventing UTI infection
InsertionInsertionUseUse anaestheticanaesthetic gel togel to meatusmeatus
Carefully position patientCarefully position patientAvoid touchingAvoid touching periurethralperiurethral
areaarea
Aseptic technique!Hand hygiene!
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Choose 10 ml balloon, narrow lumenChoose 10 ml balloon, narrow lumenunless urine has a lot of debrisunless urine has a lot of debris
SiliconeSilicone resistant to biofilm build upresistant to biofilm build up good for long term catheterisationgood for long term catheterisation
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Preventing UTI infectionPreventing UTI infection
RemovalRemovalRemove as soon as possibleRemove as soon as possible
Only change if encrustedOnly change if encrustedUse of disinfectants around meatus do notUse of disinfectants around meatus do not
appear to reduce infectionappear to reduce infection
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Preventing UTI infectionPreventing UTI infection
Avoid disconnection of catheter and bagAvoid disconnection of catheter and bag
Prevent kink in the tubePrevent kink in the tube refluxreflux
Encourage high fluid intakeEncourage high fluid intake-- lemon andlemon andcranberry drinkscranberry drinks
Aseptic handling of catheterAseptic handling of catheter
Always use gloves to handle catheter andAlways use gloves to handle catheter andwash hands afterwash hands after
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UTIUTI -- Use ofCathetersUse ofCatheters
Treatment of UTI in Catheterised patientsTreatment of UTI in Catheterised patients
Only treat asymptomatic patients with catheterOnly treat asymptomatic patients with catheteron removalon removal -- just exchange sensitive forjust exchange sensitive forresistant strainsresistant strains
Treat symptomatic infectionsTreat symptomatic infections
Encouragesantibioticresistance
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LowerRespiratory InfectionLowerRespiratory Infection
Serious LifeSerious Life--threateningthreatening
Important type of HAIImportant type of HAI
Gram negative organismsGram negative organisms KlebsiellaKlebsiellapneumoniaepneumoniae
High mortality rateHigh mortality rate
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LowerRespiratory InfectionLowerRespiratory Infection
Risk FactorsRisk Factors Inhalation of airborne particlesInhalation of airborne particles
Aspiration of material from oropharynxAspiration of material from oropharynx
Increased risk if oropharynx colonised by GramIncreased risk if oropharynx colonised by Gramnegative organismsnegative organisms
Age, illness, immunosuppressionAge, illness, immunosuppression
Antibiotics, surgery, nasogastric tubes,Antibiotics, surgery, nasogastric tubes,
endotracheal tubeendotracheal tube Supine position, unconsciousness,Supine position, unconsciousness,
AerosolsAerosols nebulisers, ventilatorsnebulisers, ventilators
Narcotics for pain reliefNarcotics for pain relief
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Supine
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LowerRespiratory InfectionLowerRespiratory Infection
Colonisation of oropharynx and stomachColonisation of oropharynx and stomach
Depletion of fibronectin allows colonisationDepletion of fibronectin allows colonisation occurs in severe illnessoccurs in severe illness
Occurs in postOccurs in post--surgical patientssurgical patients
Tubes enhance colonisation and aspirationTubes enhance colonisation and aspiration
Stomach colonised if antacids given to preventStomach colonised if antacids given to prevent
stress bleeding, also old age, gastro disease andstress bleeding, also old age, gastro disease andenteral feedsenteral feeds -- refluxreflux
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LowerRespiratory InfectionLowerRespiratory Infection
VentilationVentilation Risk increase daily by 1%Risk increase daily by 1%
Biofilm on tubeBiofilm on tube
ContaminatedContaminatedaerosolsaerosols
NebulisersNebulisers for drugsfor drugs increase colonisationincrease colonisation
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Prevention ofLRTIPrevention ofLRTI
Handwashing / alcohol rub if touching ventilatorHandwashing / alcohol rub if touching ventilatortubingtubing
Clean gloves for contact with mucousClean gloves for contact with mucous
membranesmembranes
Drain humidifier reservoirs and wash withDrain humidifier reservoirs and wash withdetergent, dry and refill every 48 hoursdetergent, dry and refill every 48 hours
Use filters with resuscitation bagsUse filters with resuscitation bags Decontaminate if possible between patientsDecontaminate if possible between patients
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Prevention ofLRTIPrevention ofLRTI
Tracheal and endotrachealTracheal and endotrachealtubes can introduce organismstubes can introduce organismsand accumulate bacteria inand accumulate bacteria in
biofilmsbiofilms Regular suctioning ofRegular suctioning of
secretionssecretions
Decontaminate suctionDecontaminate suctionequipmentequipment
Use suction catheter once onlyUse suction catheter once only
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Prevention ofLRTIPrevention ofLRTI
NebulisersNebulisers wash and dry after eachwash and dry after eachuseuse
Only use sterile solutionsOnly use sterile solutions
Oxygen delivery equipmentOxygen delivery equipment change tubing, prongs and masks afterchange tubing, prongs and masks afterevery patientevery patient
Enteral feedingEnteral feeding position patient toposition patient toprevent aspiration; prepare freshlyprevent aspiration; prepare freshly
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Enteral feed
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Prevention ofLRTIPrevention ofLRTI
PostPost--operative measures to preventoperative measures to preventpneumoniapneumonia
Breathing exercisesBreathing exercises
Pain controlPain control
Support of abdominal wounds to enable patientSupport of abdominal wounds to enable patientto cough up secretionsto cough up secretions
Prophylactic antibiotic does not reduce incidenceProphylactic antibiotic does not reduce incidenceof infectionof infection
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Other Hospital AcquiredOther Hospital Acquired
PneumoniaPneumonia
Respiratory VirusesRespiratory Viruses RSVRSV mainly children, prevent spread ofmainly children, prevent spread of
infection by isolation, gloves aprons,infection by isolation, gloves aprons,
handwashinghandwashing InfluenzaInfluenza young, elderly immunocompromised,young, elderly immunocompromised,
isolate, vaccineisolate, vaccine
SARSSARS patients with underlying illness havepatients with underlying illness have
highest mortality, isolation, strict droplethighest mortality, isolation, strict dropletprecautionsprecautions
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Other Hospital AcquiredOther Hospital Acquired
PneumoniaPneumoniaegionnaires DiseaseLegionnaires Disease
Legionella pneumophilaLegionella pneumophila
Infection from aerosolsInfection from aerosols
Cooling water from air conditioners, hot waterCooling water from air conditioners, hot watersystems, humidifiers, nebuliserssystems, humidifiers, nebulisers regular cleaningregular cleaningand disinfection, hot water above 50Cand disinfection, hot water above 50C
Elderly and imunocompromisedElderly and imunocompromised
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Other Hospital AcquiredOther Hospital Acquired
PneumoniaPneumonia
AspergillosisAspergillosisFungus in soil water andFungus in soil water and
decaying vegetablesdecaying vegetablesSpores in airSpores in air
Immunocompromised, cystic fibrosis, boneImmunocompromised, cystic fibrosis, bone
marrow transplantsmarrow transplantsFilter airFilter air
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AspergillisAspergillis
Spores
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Isolation NursingIsolation Nursing
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IsolationIsolation
Segregation of patients with infectiousSegregation of patients with infectiousdisease goes back thousands of yearsdisease goes back thousands of years
Isolation aims to prevent spread ofIsolation aims to prevent spread ofinfectious disease and nosocomialinfectious disease and nosocomialpathogenspathogens
Required when routine control cannotRequired when routine control cannotprevent spreadprevent spread
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HistoryHistory
Barrier nursingBarrier nursing
1920s sterile conditions1920s sterile conditions
1970s different isolation procedures for1970s different isolation procedures fordifferent infectionsdifferent infections too complicated!too complicated!
1990s simplified1990s simplified one basic set of rulesone basic set of rules
with some extras for specific infectionswith some extras for specific infections
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PrinciplesPrinciples
Prevent microorganisms being transmittedPrevent microorganisms being transmittedfrom infected or colonised patients to othersfrom infected or colonised patients to others
Interrupt spread of infectionInterrupt spread of infection break chainbreak chainof transmissionof transmission
Disturbing for patientDisturbing for patient use reasonableuse reasonable
precautions and as short a period asprecautions and as short a period aspossiblepossible
Consult Infection Control TeamConsult Infection Control Team
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Points to considerPoints to consider
OrganismOrganism Body site of infectionBody site of infection Transmission routeTransmission route
Are other patients / staff vulnerable?Are other patients / staff vulnerable? How can the infection be controlled?How can the infection be controlled? Consider state of the patientConsider state of the patientOften too lateOften too late use for unknown rashes oruse for unknown rashes or
pyrexiapyrexia Use for reUse for re--admissions with MRSAadmissions with MRSA
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Transmission of InfectionTransmission of Infection
In the hospital, three routes important:In the hospital, three routes important:
ContactContact
directdirect indirectindirect
DropletDroplet
AirborneAirborne
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Contact TransmissionContact Transmission
Most frequent routeMost frequent route
DirectDirect -- organisms transferred by bodilyorganisms transferred by bodily
contact between infected and uninfectedcontact between infected and uninfectedperson e.g. during bathing or turning aperson e.g. during bathing or turning apatientpatient
IndirectIndirect -- contaminated instruments orcontaminated instruments orhandshands
Prevent byPrevent by: handwashing, gloves: handwashing, gloves
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Droplet TransmissionDroplet Transmission
Respiratory secretions of patient expelledRespiratory secretions of patient expelledinto air by sneezing, coughing etc.into air by sneezing, coughing etc.
Droplets propelled up to 1 metreDroplets propelled up to 1 metre
May land on upper respiratory tractMay land on upper respiratory tractmucosa or conjunctiva of susceptible hostmucosa or conjunctiva of susceptible host----> infection> infection
Prevent byPrevent by: use of masks: use of masks
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Airborne TransmissionAirborne Transmission
Spread of small dried particles of dust orSpread of small dried particles of dust ordroplet nuclei containing infectiousdroplet nuclei containing infectiousmicroorganismsmicroorganisms
Can stay in the air for a long time and beCan stay in the air for a long time and bewidely dispersed on air currentswidely dispersed on air currents
Can be inhaled and reach the lungsCan be inhaled and reach the lungs
Prevent byPrevent by: good ventilation systems,: good ventilation systems,single room, protective clothingsingle room, protective clothing
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TransmissionTransmission--basedbased
precautio
nsprecautio
ns
Additional to standard precautionsAdditional to standard precautions
Used when patients have highlyUsed when patients have highlytransmissible or epidemiologicallytransmissible or epidemiologicallyimportant pathogensimportant pathogens
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IsolationIsolation -- STRICTSTRICT
Separate room, gowns, gloves, masks,Separate room, gowns, gloves, masks,glovesgloves
Strict hand washingStrict hand washingOwn instrumentsOwn instruments
Dressings incinerated, linen doubleDressings incinerated, linen double--baggedbagged
May need to change gloves etc if severalMay need to change gloves etc if severalprocedures carried out on same patientprocedures carried out on same patient
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IsolationIsolation -- STRICTSTRICT
Private RoomPrivate Room
For patients who contaminate theFor patients who contaminate the
environment or cannot maintain hygieneenvironment or cannot maintain hygieneOnly relevant if patient is only source ofOnly relevant if patient is only source of
organism in areaorganism in area
Profuse diarrhoea and vomiting, MRSAProfuse diarrhoea and vomiting, MRSA
Infected burns, congenital rubella, neonatalInfected burns, congenital rubella, neonatalHerpes, major skin infection, Varicella,Herpes, major skin infection, Varicella,Staphylococcal pneumoniaStaphylococcal pneumonia
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Airborne PrecautionsAirborne Precautions
Prevents transmission of organisms byPrevents transmission of organisms bydroplet nuclei or dustdroplet nuclei or dust
Private room or cohortingPrivate room or cohortingSpecial ventilationSpecial ventilation negative pressurenegative pressure
Mask, limited visitorsMask, limited visitors
Use mask for patient if movedUse mask for patient if movedMeasles, T.B., chickenpox, SARSMeasles, T.B., chickenpox, SARS
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Droplet PrecautionsDroplet Precautions
Prevents transmission of organisms byPrevents transmission of organisms bydroplets that are coughed into thedroplets that are coughed into theenvironmentenvironment
Private room or cohortingPrivate room or cohorting
Mask within 1 metreMask within 1 metre
Limit movement of patientLimit movement of patient
Patient wears mask if moved out of roomPatient wears mask if moved out of room
Pneumonia, pertussis, meningococcus,Pneumonia, pertussis, meningococcus,mumps, rubella, influenzamumps, rubella, influenza
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Contact PrecautionsContact Precautions
For patients with infections spreadFor patients with infections spreadby direct or indirect skin contactby direct or indirect skin contact
P
rivate room or cohortingP
rivate room or cohortingGloves, gownGloves, gown
Limiting movement of patientLimiting movement of patient
Avoid sharing of equipmentAvoid sharing of equipmentRubella, varicella, diarrhoea, Herpes,Rubella, varicella, diarrhoea, Herpes,skin or wound infectionskin or wound infection
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TransportTransport
Reduce movement of isolated patients toReduce movement of isolated patients toother areas of the hospitalother areas of the hospital
If necessary to transport cover infectedIf necessary to transport cover infected
lesionslesionsWear mask for airborne infectionWear mask for airborne infection
Inform mortuary if a patient has died ofInform mortuary if a patient has died of
tuberculosis, bloodborne virus ortuberculosis, bloodborne virus orCreutzfeldtCreutzfeldt--Jacob diseaseJacob disease
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VisitorsVisitors
Wash hands before leaving roomWash hands before leaving room
Restrict visitors for airborne infectionsRestrict visitors for airborne infections
Remember isolation is stressful for theRemember isolation is stressful for thepatientpatient may have behavioural problemsmay have behavioural problems
Inform/explain to patient and family soInform/explain to patient and family so
that they can be preparedthat they can be preparedDo not prolong for longer than necessaryDo not prolong for longer than necessary
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IsolationIsolation -- PROTECTIVEPROTECTIVE
Uninfected burns, severe immuneUninfected burns, severe immunedeficiency other than AIDS, radiation ordeficiency other than AIDS, radiation or
chemotherapy, leukaemia, severechemotherapy, leukaemia, severedermatitisdermatitis
However most infections from own floraHowever most infections from own flora
Private room, filtered airPrivate room, filtered airMask, gowns, gloves, strict handwashingMask, gowns, gloves, strict handwashing
Staff/visitors with RTI should stay awayStaff/visitors with RTI should stay away
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IsolationIsolation -- PROTECTIVEPROTECTIVE
Low bacteria diet, thoroughly cook meat,Low bacteria diet, thoroughly cook meat,wash fruit/veg & peeledwash fruit/veg & peeled