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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,

    Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org1

    Slide show includes

    Topic Headings

    Tables and Figures

    Key Points

    Dissociative DisordersJos R. Maldonado, M.D., F.A.P.M., F.A.C.F.E.,

    David Spiegel, M.D.

    The American Psychiatric Publishing

    TEXTBOOK OF PSYCHIATRYFifth EditionEdited by Robert E. Hales, M.D., M.B.A., Stuart C. Yudofsky, M.D., Glen O. Gabbard, M.D.

    2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org

    CHAPTER 15

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,

    Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org2

    CHAPTER 15 Topic Headings

    DEVELOPMENT OF THE CONCEPT

    MODELS AND MECHANISMS OF DISSOCIATION

    Dissociation and Information Processing

    Dissociation and Memory Systems

    Dissociation and Trauma

    Universality and Transcultural Aspects of

    Dissociation

    ACUTE STRESS DISORDER

    DISSOCIATIVE AMNESIA

    TreatmentDISSOCIATIVE FUGUE

    DEPERSONALIZATION DISORDER

    Treatment

    DISSOCIATIVE IDENTITY DISORDER

    (MULTIPLE PERSONALITY DISORDER)

    Prevalence

    Course

    Comorbidity

    Genetics

    Psychological TestingPhysiological Measures

    Treatment

    Psychotherapy

    Cognitive-Behavioral Approaches

    Psychopharmacology

    OtherTherapeutic Approaches

    Legal Aspects of Memory Work and Hypnosis

    Recall

    DISSOCIATIVE TRANCE DISORDERCultural Context

    Classification

    Dissociative Trance

    Possession Trance

    Treatment

    DISSOCIATIVE DISORDERCONVERSION TYPE?

    CONCLUSION

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,

    Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org3

    CHAPTER 15 Tables and Figures

    Table 151. DSM-IV-TR dissociative disorders

    Table 152. Differences between dissociation and repression

    Figure 151. Hippocampal and amygdalar volumes in patients with dissociative identity disorder

    (DID) and healthy comparison subjects.

    Table 153. DSM-IV-TR diagnostic criteria for acute stress disorder

    Table 154. DSM-IV-TR diagnostic criteria for dissociative amnesia

    Table 155. DSM-IV-TR diagnostic criteria for dissociative fugue

    Table 156. DSM-IV-T

    R diagnostic criteria for depersonalization disorderTable 157. DSM-IV-TR diagnostic criteria for dissociative identity disorder

    Table 158. Rules of engagement in the treatment of dissociative identity disorder

    Table 159. Guidelines for the use of hypnosis in memory work

    Table 1510. DSM-IV-TR research criteria for dissociative trance disorder

    Table 1511. Comparison of Western and Eastern types of dissociative syndromes

    Summary Key Points

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,

    Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org4

    TABLE 151. DSM-IV-TR dissociative disorders

    The dissociative disorders involve a disturbance in the integrated organization of identity, memory,

    perception, or consciousness. Events normally experienced on a smooth continuum are isolated from

    the other mental processes with which they would ordinarily be associated (Table 151).

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,

    Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org5

    TABLE 152. Differences between dissociation and repression

    Repression as a general model for keeping information out of conscious awareness differs from dissociation

    in six important ways (Table 152).

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,

    Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org6

    FIGURE 151. Hippocampal

    and amygdalar volumes in

    patients with dissociative

    identity disorder (DID) and

    healthy comparison subjects.

    There is recent evidence of a possible

    neural basis for the difficulty

    integrating traumatic memory and

    components of identity and

    consciousness among those with

    dissociative disorders. Using magneticresonance imaging, Vermetten et al.

    (2006) found that hippocampal and

    amygdalar volumes were significantly

    smaller (19% and 32%, respectively) in

    patients diagnosed with dissociative

    identity disorder compared with

    healthy volunteers (Figure 151).

    aSignificant difference between groups (P< 0.05, ttest for

    nonpaired samples).

    Source. Reprinted from Vermetten E, Schmahl C, Lindner S,

    et al: Hippocampal and Amygdalar Volumes in Dissociative

    Identity Disorder. American Journal of Psychiatry163:630636,

    2006. Copyright 2006. Used with permission.

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,

    Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org7

    TABLE 153. DSM-IV-TR diagnostic criteria for acute stress disorder

    Although acute stress disorder is classified among the anxiety disorders in DSM-IV-TR, we address it

    here because half of the symptoms of this disorder are dissociative in nature (Table 153).

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,

    Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org9

    TABLE 155. DSM-IV-TR diagnostic criteria for dissociative fugue

    Dissociative fugue combines failure of integration of certain aspects of personal memory with

    loss of customary identity and automatisms of motor behavior (Table 155).

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,

    Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org10

    TABLE 156. DSM-IV-TR diagnostic criteria for depersonalization disorder

    The essential feature of depersonalization disorder is the occurrence of persistent feelings of

    unreality, detachment, or estrangement from oneself or ones body, usually with the feeling that one is

    an outside observer of ones own mental processes. Thus, depersonalization disorder is primarily a

    disturbance in the integration of perceptual experience (Table 156).

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org

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    TABLE 157. DSM-IV-TR diagnostic criteria for dissociative identity disorder

    The number of reported dissociative identity disorder cases has risen considerably in recent years.

    Factors that may account for this increase include a more general awareness of the diagnosis among

    mental health professionals; the availability, starting with DSM-III (American Psychiatric Association

    1980), of specific diagnostic criteria (Table 157); and reduced misdiagnosis of DID as schizophrenia

    or borderline personality disorder.

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org

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    TABLE 158. Rules of engagement

    in the treatment of dissociative

    identity disorder

    Maldonado (2000) described a series of

    rules of engagement (Table 158) to be

    used in the treatment of dissociative

    identity disorder.

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org

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    TABLE 159. Guidelines for the use

    of hypnosis in memory work

    Maldonado (2000) summarized and

    adapted the guidelines provided by the

    American Medical Association (Orne et

    al. 1985) and the American Society of

    Clinical Hypnosis (Hammond et al. 1995)

    for the use of hypnosis as a method ofmemory enhancement (Table 159).

    (continued)

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org

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    TABLE 159. (continued)

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org

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    TABLE 1510. DSM-IV-TR research criteria for dissociative trance disorder

    The DSM-IV Task Force voted to include dissociative trance disorder in an appendix to DSM-IV to

    stimulate further research on the question of whether it should be a separate Axis I disorder rather than

    an example in the category of dissociative disorders not otherwise specified (Table 1510).

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    The American Psychiatric Publishing Textbook of Psychiatry, Fifth Edition. Edited by Hales RE, Yudofsky SC,Gabbard GO. 2008 American Psychiatric Publishing, Inc. All rights reserved. www.appi.org

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    TABLE 1511. Comparison of Western and Eastern types of dissociative syndromes

    Dissociative trance disorder has been divided into two broad categories: dissociative trance and

    possession trance (Table 1511).

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    CHAPTER 15 Key Points

    Dissociative disorders are underdiagnosed.

    Dissociation is a common component of acute response to trauma, anddissociative fugue, amnesia, and identity disorders often have a traumatic

    etiology.

    Dissociation represents a failure of integration of identity, memory,

    perception, and consciousness.

    The primary treatments for dissociative disorders involve various

    psychotherapies, including hypnosis, trauma-related psychotherapies, andcognitive therapies.

    Common comorbid conditions requiring treatment include depression,

    substance use disorders, and borderline personality disorder.

    Dissociative symptoms are ubiquitous around the world, but the content of

    the dissociative symptoms varies, involving possession by external entities

    more often in the East, and fragmentation of individual identity in the West.