15.1 lipids 15.2 fatty acids · lipids lipids are • biomolecules that contain fatty acids or a...
TRANSCRIPT
![Page 1: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/1.jpg)
1
Chapter 15 Lipids
15.1 Lipids 15.2 Fatty Acids
Copyright © 2009 by Pearson Education, Inc.
![Page 2: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/2.jpg)
2
Lipids
Lipids are • biomolecules that contain fatty acids or a steroid
nucleus. • soluble in organic solvents, but not in water. • named for the Greek word lipos, which means
“fat.” • extracted from cells using organic solvents.
![Page 3: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/3.jpg)
3
Types of Lipids
The types of lipids containing fatty acids are • waxes • fats and oils (triacylglycerols) • glycerophospholipids • prostaglandins
The types of lipids that do not contain fatty acids are • steroids
![Page 4: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/4.jpg)
4
Classes of Lipids
![Page 5: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/5.jpg)
5
Fatty Acids
Fatty acids are • long-chain carboxylic acids. • typically 12-18 carbon atoms. • insoluble in water. • saturated or unsaturated.
Olive oil contains 84% unsaturated fatty acids and 16% saturated fatty acids.
Copyright © 2009 by Pearson Education, Inc.
![Page 6: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/6.jpg)
6
Saturated and Unsaturated Fatty Acids
Fatty acids are • saturated with
all single C–C bonds.
• unsaturated with one or more double C=C bonds.
![Page 7: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/7.jpg)
7
Properties of Saturated Fatty Acids
Saturated fatty acids • contain only single C–C bonds.
• are closely packed.
• have strong attractions between chains.
• have high melting points.
• are solids at room temperature.
![Page 8: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/8.jpg)
8
Properties of Unsaturated Fatty Acids
Unsaturated fatty acids • contain one or more cis double C=C
bonds. • have “kinks” in the fatty acid chains. • do not pack closely. • have few attractions between chains. • have low melting points. • are liquids at room temperature.
“kinks” in chain
![Page 9: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/9.jpg)
9
Melting Points of Some Saturated Fatty Acids
Copyright © 2009 by Pearson Education, Inc.
![Page 10: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/10.jpg)
10
Melting Points of Some Unsaturated Fatty Acids
![Page 11: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/11.jpg)
11
Learning Check
Assign the melting points of –17 °C, 13 °C, and 69 °C to the correct fatty acid. Explain.
stearic acid (18 C) saturated oleic acid (18 C) one double bond linoleic acid (18 C) two double bonds
![Page 12: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/12.jpg)
12
Solution
Stearic acid is saturated and would have a higher melting point than the unsaturated fatty acids. Because linoleic has two double bonds, it would have a lower mp than oleic acid, which has one double bond.
stearic acid mp 69 °C saturated oleic acid mp 13 °C
linoleic acid mp -17 °C most unsaturated
![Page 13: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/13.jpg)
13
Chapter 15 Lipids
15.3 Waxes, Fats, and Oils
![Page 14: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/14.jpg)
14
Waxes
Waxes are • esters of saturated fatty acids and long-chain alcohols. • coatings that prevent loss of water by leaves of plants.
![Page 15: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/15.jpg)
15
Fats and Oils: Triacylglycerols
Fats and oils are • also called triacylglycerols. • esters of glycerol. • produced by esterification. • Formed when the hydroxyl
groups of glycerol react with the carboxyl groups of fatty acids.
Copyright © 2009 by Pearson Education, Inc.
![Page 16: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/16.jpg)
16
In a triacylglycerol, glycerol forms ester bonds with three fatty acids.
Triacylglycerols
Copyright © 2009 by Pearson Education, Inc.
Ester Bonds
![Page 17: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/17.jpg)
17
Formation of a Triacylglycerol
Glycerol + three fatty acids triacylglycerol
+ 3H2O
+
![Page 18: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/18.jpg)
18
Learning Check
What are the fatty acids in the following triacylglycerol?
![Page 19: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/19.jpg)
19
Solution
Stearic acid
Oleic acid
Myristic acid
![Page 20: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/20.jpg)
20
Melting Points of Fats and Oils
A fat • is usually solid at room temperature. • is prevalent in meats, whole milk, butter, and cheese. An oil • is usually liquid at room temperature. • is prevalent in plants such as olive and safflower.
![Page 21: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/21.jpg)
21
Oils with Unsaturated Fatty Acids
Oils • have more unsaturated fats. • have cis double bonds that cause “kinks” in the fatty
acid chains. • with “kinks” in the chains do not allow the
triacylglycerol molecules to pack closely. • have lower melting points than saturated fatty acids. • are liquids at room temperature.
![Page 22: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/22.jpg)
22
Diagram of Triacylglycerol with Unsaturated Fatty Acids
Unsaturated fatty acid chains with kinks cannot pack closely.
![Page 23: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/23.jpg)
23
Percent Saturated and Unsaturated Fatty Acids In Fats and Oils
![Page 24: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/24.jpg)
24
Chapter 15 Lipids
15.4 Chemical Properties of Triacylglycerols
Copyright © 2009 by Pearson Education, Inc.
![Page 25: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/25.jpg)
25
The chemical reactions of triacylglycerols are similar to those of alkenes and esters.
• In hydrogenation, double bonds in unsaturated fatty acids react with H2 in the presence of a Ni or Pt catalyst.
• In hydrolysis, ester bonds are split by water in the presence of an acid, a base, or an enzyme.
Chemical Properties of Triacylglycerols
![Page 26: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/26.jpg)
26
Hydrogenation of Oils
The hydrogenation of oils
• adds hydrogen (H2) to the carbon atoms of double bonds. • converts double bonds to single bonds. • increases the melting
point. • produces solids, such as
margarine and shortening.
![Page 27: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/27.jpg)
27
Hydrogenation
Ni + 3H2
Glyceryl tripalmitoleate (tripalmitolean)
Glyceryl tripalmitate (tripalmitin)
![Page 28: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/28.jpg)
28
What products are obtained from the complete hydrogenation of glyceryl trioleate?
1. Glycerol and 3 oleic acids 2. Glyceryltristearate 3. Glycerol and 3 stearic acids
Learning Check
![Page 29: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/29.jpg)
29
What products are obtained from the complete hydrogenation of glyceryl trioleate?
2. Glyceryltristearate
Solution
![Page 30: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/30.jpg)
30
OlestraTM, a Fat Substitute
Olestra is • used in foods as an artificial fat. • sucrose linked by ester bonds to several long-chain fatty
chains. • not broken down in the intestinal tract.
![Page 31: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/31.jpg)
31
Cis and Trans Fatty Acids
Unsaturated fatty acids can be • cis with bulky groups on same side of C=C. CH3─ (CH2)5 (CH2)7─ COOH cis
C=C
H H • trans have bulky groups on opposite sides of C=C. CH3─ (CH2)5 H
C=C trans
H (CH2)7─ COOH
![Page 32: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/32.jpg)
32
Hydrogenation and Trans Fatty Acids
Most naturally occurring fatty acids have cis double bonds. • During hydrogenation, some cis double bonds are converted to
trans double bonds. • In the body, trans fatty acids behave like saturated fatty acids. • It is estimated that 2-4% of our total Calories is in the form of
trans fatty acid. • Several studies reported that trans fatty acids raise LDL-
cholesterol and lower HDL-cholesterol.
![Page 33: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/33.jpg)
Hydrogenation of Unsaturated Fats
33
![Page 34: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/34.jpg)
34
Learning Check
(1) True or (2) false:
A. There are more unsaturated fats in vegetable oils. B. Vegetable oils have higher melting points than fats. C. Hydrogenation of oils converts some cis-double bonds
to trans-double bonds. D. Animal fats have more saturated fats.
![Page 35: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/35.jpg)
35
Solution
(1) True or (2) false:
A. T There are more unsaturated fats in vegetable oils. B. F Vegetable oils have higher melting points than fats. C. T Hydrogenation of oils converts some cis-double
bonds to trans- double bonds. D. T Animal fats have more saturated fats.
![Page 36: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/36.jpg)
36
Hydrolysis
In hydrolysis, • triacylglycerols split into glycerol and three fatty acids. • an acid or enzyme catalyst is required.
+
+
![Page 37: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/37.jpg)
37
Saponification and Soap
Saponification • is the reaction of a fat with a strong base. • splits triacylglycerols into glycerol and the salts of fatty
acids. • is the process of forming “soaps” (salts of fatty acids). • with KOH gives softer soaps.
![Page 38: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/38.jpg)
38
Saponification
+ 3NaOH
3+ “soap”
![Page 39: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/39.jpg)
39
What products are obtained from the complete hydrolysis of glyceryl trioleate?
1. Glycerol and 3 oleic acids 2. Glyceryl tristearate 3. Glycerol and 3 stearic acids
Learning Check
![Page 40: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/40.jpg)
40
What products are obtained from the complete hydrolysis of glyceryl trioleate?
1. Glycerol and 3 oleic acids
Solution
![Page 41: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/41.jpg)
41
Learning Check
Write the product of the following reaction:
+ 3
![Page 42: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/42.jpg)
42
Solution
C
O
( C H 2 ) 1 4 C H 3
C ( C H 2 ) 1 4 C H 3
O
C
O
( C H 2 ) 1 4 C H 3
C H 2 O
C H
C H 2
O
O
![Page 43: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/43.jpg)
43
Chapter 15 Lipids
15.5 Glycerophospholipids
Glycerol
PO4 Amino alcohol
Fatty acid
Fatty acid
![Page 44: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/44.jpg)
44
Glycerophospholipids are • the most abundant lipids in cell membranes. • composed of glycerol, two fatty acids, phosphate,
and an amino alcohol.
Glycerol
PO4 Amino alcohol
Glycerophospholipids
Fatty acid
Fatty acid
![Page 45: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/45.jpg)
45
Polarity of Glycerophospholipids
A glycerophospholipid has • two nonpolar fatty acid chains. • a phosphate group and a polar amino alcohol. CH3 │+ + HO−CH2−CH2−N−CH3 HO−CH2−CH2−NH3
│ Choline CH3 Ethanolamine + NH3 │ Amino alcohols HO−CH2−CH−COO− Serine
![Page 46: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/46.jpg)
46
Structure and Polarity of a Glycerophospholipid
![Page 47: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/47.jpg)
47
Lecithin and cephalin are glycerophospholipids • abundant in brain and nerve tissues. • found in egg yolk, wheat germ, and yeast.
Lecithin and Cephalin
Copyright © 2009 by Pearson Education, Inc.
![Page 48: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/48.jpg)
48
Learning Check
Identify each as A. fatty acid B. triacylglycerol C. amino alcohol D. glycerophospholipid
1. glyceryl trioleate 2. cephalin 3. choline 4. palmitic acid
![Page 49: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/49.jpg)
49
Solution
Identify each as A. fatty acid B. triacylglycerol C. amino alcohol D. glycerophospholipid
1. glyceryl trioleate B. triacylglycerol 2. cephalin D. Glycerophospholipid 3. choline C. amino alcohol 4. palmitic acid A. fatty acid
![Page 50: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/50.jpg)
50
Chapter 15 Lipids
15.6 Steroids: Cholesterol and Steroid
Hormones
Copyright © 2009 by Pearson Education, Inc.
![Page 51: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/51.jpg)
51
Steroid Nucleus
A steroid nucleus consists of
• 3 cyclohexane rings. • 1 cyclopentane ring. • no fatty acids.
steroid nucleus
![Page 52: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/52.jpg)
52
Cholesterol
Cholesterol • is the most abundant steroid in the body. • has methyl CH3- groups, alkyl chain, and -OH
attached to the steroid nucleus.
![Page 53: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/53.jpg)
53
Cholesterol in the Body
Cholesterol • is obtained from meats, milk, and
eggs. • is synthesized in the liver. • is needed for cell membranes, brain
and nerve tissue, steroid hormones, and vitamin D.
• clogs arteries when high levels form plaque.
An artery clogged by cholesterol plaque
A normal, open artery.
![Page 54: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/54.jpg)
54
Cholesterol in Foods
Cholesterol • is considered
elevated if plasma cholesterol exceeds 200 mg/dL.
• is synthesized in the liver and obtained from foods.
![Page 55: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/55.jpg)
55
Learning Check
Match the components of the cholesterol molecule with the following: ___ carbon chain ___hydroxyl group ___ steroid nucleus ___methyl group
A C
B
D
![Page 56: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/56.jpg)
56
Solution
Match the components of the cholesterol molecule with the following: _D carbon chain _A_hydroxyl group _C steroid nucleus _B_methyl group
A C
B
D
![Page 57: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/57.jpg)
57
Lipoproteins
Lipoproteins • combine lipids
with proteins and phospholipids.
• are soluble in water because the surface consists of polar lipids.
![Page 58: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/58.jpg)
58
Types of Lipoproteins
Lipoproteins • differ in density, composition, and function. • include low-density lipoproteins (LDLs) and high-
density lipoproteins (HDLs).
![Page 59: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/59.jpg)
59
Transport of Lipoproteins in the Body
![Page 60: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/60.jpg)
60
Steroid Hormones
Steroid hormones are • chemical messengers in cells. • sex hormones.
- androgens in males (testosterone) - estrogens in females (estradiol)
• Adrenocortical hormones from adrenal glands. - mineralocorticoids (electrolyte balance) - glucocorticoids (regulate glucose level)
![Page 61: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/61.jpg)
61
Steroid Hormones
Steroid hormones • are produced from
cholesterol.
• include sex hormones such as androgens (testosterone) in males and estrogens (estradiol) in females.
Copyright © 2009 by Pearson Education, Inc.
![Page 62: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/62.jpg)
62
Adrenal Corticosteroids
Steroid hormones called adrenal corticosteroids • are produced by the adrenal glands located on the top
of each kidney. • include aldosterone, which regulates electrolytes and
water balance by the kidneys. • include cortisone, a glucocorticoid, which increases
blood glucose level and stimulates the synthesis of glycogen in the liver.
![Page 63: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/63.jpg)
63
Anabolic Steroids
Anabolic steroids • are derivatives of testosterone. • are used illegally to increase muscle mass. • have side effects including fluid retention, hair growth,
sleep disturbance, and liver damage.
Copyright © 2009 by Pearson Education, Inc.
![Page 64: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/64.jpg)
64
Adrenal Corticosteroids
Copyright © 2009 by Pearson Education, Inc.
![Page 65: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/65.jpg)
65
Learning Check
Identify each lipid as a (1) fatty acid, (2) steroid, or (3) triacylglycerol.
A. cholesterol B. stearic acid C. glyceryl tristearate D. estradiol E. contains no fatty acids
![Page 66: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/66.jpg)
66
Solution
Identify each lipid as a (1) fatty acid, (2) steroid, or (3) triacylglycerol. A. 2 cholesterol B. 1 stearic acid C. 3 glyceryl tristearate D. 2 estradiol E. 2 contains no fatty acids
![Page 67: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/67.jpg)
67
Chapter 15 Lipids
15.7 Cell Membranes
![Page 68: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/68.jpg)
68
Cell Membranes
Cell membranes • separate cellular contents from the external
environment. • consist of a lipid bilayer made of two rows of
phospholipids. • have an inner portion made of the nonpolar tails of
phospholipids with the polar heads at the outer and inner surfaces.
![Page 69: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/69.jpg)
69
Fluid Mosaic Model of Cell Membranes
The lipid bilayer
• contains proteins, carbohydrates, and cholesterol.
• has unsaturated fatty acids that make cell membranes fluid-like rather than rigid.
• has proteins and carbohydrates on the surface that communicate with hormones and neurotransmitters.
![Page 70: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/70.jpg)
70
Fluid Mosaic Model of Cell Membranes
![Page 71: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/71.jpg)
71
Transport Through Cell Membranes
The transport of substances through cell membranes
involves
• diffusion (passive transport), which moves particles from a higher to a lower concentration.
• facilitated transport, which uses protein channels to increase the rate of diffusion.
• active transport, which moves ions against a concentration gradient.
![Page 72: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/72.jpg)
72
Transport Pathways Through Cell Membranes
Copyright © 2009 by Pearson Education, Inc.
![Page 73: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/73.jpg)
73
Learning Check
The transport of particles across a cell membrane from
high concentration to low concentration is called
1. facilitated transport.
2. diffusion.
3. active transport.
![Page 74: 15.1 Lipids 15.2 Fatty Acids · Lipids Lipids are • biomolecules that contain fatty acids or a steroid nucleus. • soluble in organic solvents, but not in water. • named for](https://reader030.vdocuments.net/reader030/viewer/2022040414/5f1a119c58df326b8f65dea1/html5/thumbnails/74.jpg)
74
Solution
The transport of particles across a cell membrane from high concentration to low concentration is called
2. diffusion.