1h nmr (varian, 400 mhz) spectrum of compound 3a in cdcl

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1 1 H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl 3 N O Copies of spectra Electronic Supplementary Material (ESI) for Organic & Biomolecular Chemistry. This journal is © The Royal Society of Chemistry 2014

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Page 1: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

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Copies spectra

1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl3

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N

O

Copies of spectra

Electronic Supplementary Material (ESI) for Organic & Biomolecular Chemistry.This journal is © The Royal Society of Chemistry 2014

Page 2: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

2�

13C NMR spectrum (Varian, 100 MHz) of compound 3a in CDCl3

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N

O

Page 3: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

3�

N

O

Page 4: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

4�

1H NMR (Varian, 400 MHz) spectrum of compound 3b in CDCl3

13C NMR spectrum (Varian, 100 MHz) of compound 3b in CDCl3

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N

O Cl

N

O Cl

Page 5: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

5�

N

O Cl

Page 6: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

6�

1H NMR (Varian, 400 MHz) spectrum of compound 3c in CDCl3 + rotamers

N

O

I

Page 7: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

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������������������������������13C NMR spectrum (Varian, 100 MHz) of compound 3c in CDCl3�

N

O

I

Page 8: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

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N

O

I

Page 9: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

9�

1H NMR (Varian, 400 MHz) spectrum of compound 3d in CDCl3

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N

O

Cl

Br

Page 10: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

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������������������������13C NMR spectrum (Varian, 100 MHz) of compound 3d in CDCl3 �

N

O

Cl

Br

Page 11: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

11�

N

O

Cl

Br

Page 12: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

12�

1H NMR (Varian, 400 MHz) spectrum of compound 3e in CDCl3

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N

O

Br

Page 13: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

13�

13C NMR spectrum (Varian, 100 MHz) of compound 3e in CDCl3�

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N

O

Br

Page 14: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

14�

N

O

Br

Page 15: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

15�

1H NMR (Varian, 400 MHz) spectrum of compound 3f in CDCl3 �

N

O

Cl

Page 16: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

16�

����������� 13C NMR spectrum (Varian, 100 MHz) of compound 3f in CDCl3�

N

O

Cl

Page 17: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

17�

N

O

Cl

Page 18: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

18�

1H NMR (Varian, 400 MHz) spectrum of compound 3g in CDCl3 �

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N

O

Cl

Page 19: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

19�

�������������������������������13C NMR spectrum (Varian, 100 MHz) of compound 3g in CDCl3�

N

O

Cl

Page 20: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

20�

N

O

Cl

Page 21: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

21�

1H NMR (Varian, 400 MHz) spectrum of compound 3h in CDCl3 ���

N

O

H3C

Page 22: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

22�

13C NMR spectrum (Varian, 100 MHz) of compound 3h in CDCl3�

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N

O

H3C

Page 23: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

23�

N

O

H3C

Page 24: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

24�

1H NMR (Varian, 400 MHz) spectrum of compound 3i in CDCl3 ����

N

O CH3

Page 25: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

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�����������������������������������13C NMR spectrum (Varian, 100 MHz) of compound 3i in CDCl3 �

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N

O CH3

Page 26: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

26�

N

O CH3

Page 27: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

27�

1H NMR (Varian, 400 MHz) spectrum of compound 3j in CDCl3 ���

N

O I

Page 28: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

28�

13C NMR spectrum (Varian, 100 MHz) of compound 3j in CDCl3 �

N

O I

Page 29: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

29�

N

O I

Page 30: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

30�

1H NMR (Varian, 400 MHz) spectrum of compound 3k in CDCl3 ��

��

N

O

Cl

Cl

Page 31: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

31�

13C NMR spectrum (Varian, 100 MHz) of compound 3k in CDCl3 �

��

N

O

Cl

Cl

Page 32: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

32�

N

O

Cl

Cl

Page 33: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

33�

1H NMR (Varian, 400 MHz) spectrum of compound 3l in CDCl3 ����

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N

O

Cl

Cl

Page 34: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

34�

13C NMR spectrum (Varian, 100 MHz) of compound 3l in CDCl3 �

��

N

O

Cl

Cl

Page 35: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

35�

N

O

Cl

Cl

Page 36: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

36�

1H NMR (Varian, 400 MHz) spectrum of compound 3m in CDCl3 ���

N

O

ClCl

Page 37: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

37�

13C NMR spectrum (Varian, 100 MHz) of compound 3m in CDCl3��

N

O

ClCl

Page 38: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

38�

N

O

ClCl

Page 39: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

39�

1H NMR (Varian, 400 MHz) spectrum of compound 3n in CDCl3 ���

N

O

Cl

Cl

Page 40: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

40�

13C NMR spectrum (Varian, 100 MHz) of compound 3n in CDCl3��

N

O

Cl

Cl

Page 41: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

41�

N

O

Cl

Cl

Page 42: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

42�

1H NMR (Varian, 400 MHz) spectrum of compound 3o in CDCl3 ���

N

O

Cl

Cl

Page 43: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

43�

13C NMR spectrum (Varian, 100 MHz) of compound 3o in CDCl3��

��

N

O

Cl

Cl

Page 44: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

44�

N

O

Cl

Cl

Page 45: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

1H NMR (Varian, 400 MHz) spectrum of compound 3p in CDCl3��

N

O

Page 46: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

13C NMR spectrum (Varian, 100 MHz) of compound 3p in CDCl3

N

O

Page 47: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

1H NMR (Varian, 400 MHz) spectrum of compound 3q in CDCl3��

Page 48: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

13C NMR spectrum (Varian, 100 MHz) of compound 3q in CDCl3

Page 49: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

1H NMR (Varian, 400 MHz) spectrum of compound 3r in CDCl3

� 13C NMR spectrum (Varian, 100 MHz) of compound 3r in CDCl3

Page 50: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

45�

1H NMR (Varian, 400 MHz) spectrum of compound 4a in CDCl3 ���

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N

O Ph

PhO

Page 51: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

46�

13C NMR spectrum (Varian, 100 MHz) of compound 4a in CDCl3��

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N

O Ph

PhO

Page 52: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

47�

N

O Ph

PhO

Page 53: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

48�

1H NMR (Varian, 400 MHz) spectrum of compound 4b in CDCl3 ���

N

O Ph

OCH3

Page 54: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

49�

13C NMR spectrum (Varian, 100 MHz) of compound 4b in CDCl3��

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N

O Ph

OCH3

Page 55: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

50�

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N

O Ph

OCH3

Page 56: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

1H NMR (Varian, 400 MHz) spectrum of compound 5a in CDCl3��

NH

PhO

5a

Page 57: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

51�

1H NMR (Varian, 400 MHz) spectrum of compound 5a in CDCl3 ���5b

Page 58: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

52�

13C NMR spectrum (Varian, 100 MHz) of compound 5a in CDCl3�

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5b

Page 59: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

53�

1H NMR (Varian, 400 MHz) spectrum of compound 6 in CDCl3 ����

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N

7

Page 60: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

54�

13C NMR spectrum (Varian, 100 MHz) of compound 6 in CDCl3��

N

7

Page 61: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

55�

IH NMR (Varian, 400 MHz) spectrum of compound 7 in CDCl3 ���

N

O

8

Page 62: 1H NMR (Varian, 400 MHz) spectrum of compound 3a in CDCl

56�

13C NMR spectrum (Varian, 100 MHz) of compound 7 in CDCl3��

N

O

8