1st prof mbbs regu

8/20/2019 1st Prof Mbbs Regu

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Rules, Regulations and Syllabus for First Professional MBBS

course of West Bengal University of Health Sciences

1. The period of study for the first Professional MBBS course will consist of two

semesters, each of six months duration. The first semester will ordinarily commence in the month

of August, and the second semester, in the month of Feruary next year. The first ProfessionalMBBS !xamination will e held at the end of the "nd semester.

". There shall e two #ni$ersity examinations in a year% one regular and one

supplementary first professional MBBS !xamination. The regular First Professional !xaminationwill e completed and the results pulished within mid%Septemer of each year. The

supplementary examination will e held ordinarily not earlier than six &'( wee)s, ut not later

than six months, after the pulication of the results of the regular examination.

*. !ligiility +riteria of the Students for appearing in the 1 st Professional MBBS

examination% An undergraduate medical student who has fulfilled the following conditions may

e admitted to the First Professional MBBS !xamination of this #ni$ersity.

&a( That heshe has completed the age of 1- years on or efore *1st ecemer of the year of hisher admission to a college of medicine affiliated to this #ni$ersity for conduction of MBBS

course of studies.

&( That heshe has passed the pre%medical /.Sc. 10" years 2igher Secondary !xamination,

or an e3ui$alent examination from a recogni4ed Board #ni$ersity with Physics, +hemistry,

Biological Sciences, !nglish, and a 5ernacular su6ect.

&c( That heshe has compulsorily attended a regular course of study for the prescried period in

a college of Medicine affiliated to this #ni$ersity. A minimum of -78 attendance in all the

su6ects is compulsory &including attendance in non%lecture classes li)e demonstration, practical,

tutorial, seminar, group discussion etc.(. The attendance has to e certified y the Principal

irector of the affiliated institution. There is no pro$ision of condonation of shortage of attendance &due to any cause whatsoe$er(, or of appearance as non%collegiate candidate under any

circumstances, whatsoe$er.&d( Students not eing allowed to sit for the regular examination due to shortage of attendance

may e permitted to attend special classes to ma)e good the shortage in attendance to enale such

candidates to appear in the supplementary examination, if they already possess an attendance of

'08 or ao$e. 9o such proposal of ma)ing good shortage in attendance efore next

supplementary examination will, howe$er, e entertained for permission to sit for the same

regular examination. +andidates ha$ing attendance of less than '08 will ha$e to start the classes

afresh for the next regular examination of next atch.

&e( For eing admitted to the regular or supplementary examination, each candidate shall

send hisher application in the prescried form to the +ontroller of !xamination along with the

fee as will e prescried y the #ni$ersity from time to time. The applications forwarded y the

2ead of the /nstitution of the affiliated college shall ha$e to reach the #ni$ersity at least * wee)s

efore the commencement of the #ni$ersity examination. The examination fee of any regularsupplementary examination shall not e refunded or carried forward in cases of failure or non%

appearance of a candidate in the particular regular supplementary examination.

&f( That he has fulfilled the criteria as laid down in Para - elow.

:. &a( +andidates appearing for the regular 1st Professional MBBS examination shall appear in

theory, oral and practical examination in the examination center located in hisher own

collegeinstitution. 2owe$er, during supplementary examination the numer of centers for

1


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supplementary examination will depend upon the numer of candidates appearing for the

supplementary examination and the geographical location of the institution.

&( Preferaly not more that *0 candidates will e examined on any day for practical and oral

examination in a particular su6ect.

7. &a(. For smooth conduction of the theory, oral and practical examination, there will e one+enter%in%charge for the 1st Professional MBBS examination in each of the centers. The +enter%

in%charge will preferaly e a senior teacher not elow the ran) of Assoc. Prof. 2e she will not participate as an internal examiner of any su6ect in the 1 st Professional MBBS examination. The

+enter%in%charge and the office of the Principalirector of the /nstitution shall e responsile for

smooth conduction of the examination.

&(. For coordination of the whole examination programme there will e one +hairman%cum%

internal examiner for each su6ect of the 1st Professional MBBS examination in each of the

centers. 2eshe will preferaly e the senior%most teacher amongst the internal examiners. 2eshe

will ma)e the necessary arrangements for smooth conduction of the oral and practical

examination as well as for e$aluation of the theory papers in that su6ect. The +enter%in%charge,

after collecting all the related documents within " days of completion of the oral and practical

examination from the +hairpersons of different su6ects, will arrange to send all the papers to the

#ni$ersity within : days after completion of the 1st Professional MBBS !xamination. The

#ni$ersity will also appoint a scrutini4er for each su6ect in each center. 2eshe will usually e a 6unior teacher of the same department.

&c ( The +hairman shall ha$e statutory power of last minute selection of examiners &oth

external and internal(, in consultation with ;ser$erean+enter%in%charge, if any exigency

arises.

'. !xaminers.

i( The examiners in any su6ect should preferaly hold at least a ran) of est Bengal (Externals(. /n case of fi$e examiners in a su6ect one will e preferaly from an

institution of the state, other than the institution in which the center is located. A reser$e list of

external and internal examiners shall e )ept to meet any exigency that may crop up . Such list of examiners may include recently retired senior teachers of any recogni4ed uni$ersity.

iii( >hen fi$e examiners are appointed for a center, one of the internal examiners will e

spared from chec)ing the answer scripts of the theory papers y the +hairman of the su6ect. i$( The internal examiner in a su6ect shall not accept external examiner%ship for a collegeout side the State from which external examiner is appointed in hisher college in hisher su6ect.

$( The external examiners for any particular center may remain the same maximum for a period of two consecuti$e years. Thereafter heshe may e reappointed after an inter$al of two

years.

$i( /n each su6ect, the theory 3uestion papers will e in$ited from the +hairman of all the

centers. /n each su6ect, there will also e a Moderator, who will preferaly e a senior faculty

memer of any recogni4ed medical college from states other than >est Bengal and will e

selected y the Board of Studies of the #ni$ersity. The Moderator will moderate the 3uestion

paper. /n case of exigency, the #ni$ersity may appoint a retired Professor as a$ailale in >est

Bengal as moderator.

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$ii( The uni$ersity may appoint suitale oser$ers#ni$ersity B#2S Theory ;ral Practical Total Per%

*


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9o. the

+andidate


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Practical = 40 marks

Internal ssessment (!"e#r$ 20%Practical 20 = 40 marks

Full mar)s C "00 mar)s

&c( Answer to each 3uestion should e gi$en y the candidates in a separate answer script.To ensure maximum possile uniformity during assessment only one examiner will

examine all the answer scripts of the same 3uestion in the same center.&d( Practicalclinical examination will e conducted in the practical roomdissection

roomlaoratory roomhospital wards of the concerned medical college. ;6ecti$e will

e to assess proficiency in s)ills, conduct of experiment, interpretation of data, and

interpretation of common in$estigation data, D%rays, identification of

specimensinstruments etc. and to assess proficiency to ma)e logical conclusion.

&e( 5i$aoral will e held in two tales with minimum two examiners in each tale.

/nstruments, e3uipments, chemicals, specimens, charts etc. as will e re3uired in

different su6ects, will e used for ta)ing oral$i$a examinations.

E. Result

i( All the examiners will e 6ointly responsile for the result of all parts of the

examination. The decision of the +hairman after consultation with the +enter%in chargewill e final in the case of exigency.

ii( The #ni$ersity shall pulish the list of successful Pass and 2onours candidates

preferaly within * wee)s after the last date of the 1st Professional MBBS !xamination.

!ach candidate shall recei$e a mar) sheet showing the mar)s secured y himher ineach su6ect.

iii( /n order to pass a su6ect, a candidate must otain separately &a( a minimum of

708 in Theory including ;ralsG &( a minimum of 708 in Practicals and &c( a minimum

of 708 in aggregate.

For !xample, in order to pass in the su6ect of Anatomy, a student will ha$e to ha$e

minimum '0 mar)s out of 1"0 in theory including orals, "0 mar)s out of :0 in

practicals and minimum of 100 mar)s out of "00 in aggregate.

i$( +redit of passed su6ect&s( will e retainedG i.e., an unsuccessful candidate whohas passed in one or more su6ects is not re3uired to appear in that those su6ect&s(.

$( A candidate who has failed to pass in any of the su6ects in the 1 st Professional

MBBS !xamination shall e declared unsuccessful in the !xamination and shall not e

allowed to 6oin the "nd Professional +ourse until heshe passes in all the su6ects of the

1st Professional +ourse.

$i( There shall e no separate examination for 2onours. A candidate securing -78mar)s in aggregate in a su6ect shall e declared to ha$e secured 2onours in the

su6ect&s( pro$ided that heshe has passed in all the su6ects for the 1 st Professional

!xamination in the first attempt.

$ii( 9otwithstanding anything contained anywhere in the rele$ant regulations it is pro$ided that the candidate, who, in spite of otaining 778 or ao$e mar)s in the

aggregate in a su6ect, ecame unsuccessful in a compartment of that su6ect for 7 or less mar)s shall e awarded up to fi$e mar)s in that particular compartment after

deducting the same from other compartment&s( of that su6ect, pro$ided that he she has

passed in all other su6ects in the same examination.

$iii( There will e no pro$ision for re$iew of the answer scripts or any part of the

examination in any circumstances.

Pro#osed Routine $f %st Prof& MBBS 'ourse For % *nnual *d"issions&

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ay %E

am

E%10 am 10%11

am

11%1"

noon

1"%1.*0 pm 1.*0%" pm "%: pm

Anat Physio Bioch

Mon Physio Anat Anat Batch A Batch B Batch +


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*& Written Pa#er+

Paper I Superior !xtremity, /nferior !xtremity, Adomen ? Pel$is with rele$ant

!mryology ? histology, and, =eneral !mryology.

Paper II - Thorax, 2ead ? 9ec), +entral 9er$ous System, Bulous ;culi, >ith

rele$ant !mryology ? histology, =enetics, and, =eneral Anatomy.

!"e 'r 'esti#ns in eac" t"e#r$ paper ill pre&era*l$ "ave t"e ll#in+ ,istri*'ti#n #& marks.

-. 1) One l#n+ essa$ t$pe 'esti#n (#'t #& t#) c#nsistin+ #& 24 small se+ments. arks

r eac" se+ment ill *e in,icate, separatel$. arks ma$ *e 12.

-. 2) !# s"#rt essa$ t$pe 'esti#n (#'t #& t"ree) eac" c#nsistin+ #& 2 small se+ments

an, marks r eac" se+ment ill *e in,icate, separatel$. arks ma$ *e 14 ( x 2).

-. ) 3#'r s"#rt n#tes (#'t #& &ive ). arks ma$ *e12 ( x 4)

-. 4) 3#'r s"#rt clinicall$ #riente, explanat#r$ n#tes (#'t #& 'r). arks ma$12 ( x 4)

*ns.er to each /uestion should be given by the candidates in a se#arate ans.er

boo0

$nly one e!a"iner .ill e!a"ine all the ans.er scri#ts to the sa"e /uestion of the

#a#er in that center& Preferably each e!ternal e!a"iner .ill e!a"ine ans.er scri#t

of 12 of one #a#er 3 14 of the other #a#er& ach e!a"iner .ill e!a"ine ans.ers to

one /uestion of each #a#er&

B& $ral56ivai( For 3uestions on ;steology with general anatomy % " mar)s

(2 *#nes &r#m appen,ic'lar skelet#n 2 *#nes &r#m axial skelet#n)

i( For 3uestions on 5iscera with !mryology %" mar)s&4 specimens #ne eac" &r#m 'pper a*,#men Pelvis/t"#rax ea, neck 6rain/

E$e*all).

'& Practical+

o Windo. 7issection 10 mar)s

o 8dentification 1" mar)s&7 structures, one each from each part of the ody one cross section from

any part of the ody are to e identifications are to e gi$en as flag mar)s

and they will e same for the whole atch of the same day. 0.7 mar)s for

each identification and three 3uestions on each item $alued I 0.7 each.

o Surface "ar0ing - ' mar)s &line drawing : mar)s

point " mar)s(o Radiology * mar)s

o Histology E mar)s &7 stained slides for

identification 1 mar) each

1 special side : mar)s(

7& 8nternal *ssess"ent Mar0s+ Total mar)s%:0

7istribution of 8nternal *ssess"ent Mar0s

%& 'ontinuous 7aytoday *ssess"ent

-


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Parts of the

Body

$R*9 PR*':8'*9

Full Mar0s Mar0s

$btained

Full Mar0s Mar0s

$btainedSup. !xtremity 17 17

/nf. !xtremity 17 17

Adomen "7 "7Thorax 10 10

2ead ? 9ec) "0 "0

+9S ? !yeall 17 17

Total 100 100

108 of the

Mar)s

10 A 10 B

;B *t ti"e of co"#letion of a #art, the "ar0s for different ite"s should offered

after considering overall #erfor"ance 3 regularity in attendance

2& Periodical 8nstitution *ssess"ent !a"ination

WR8::; PR*':8'*9

Full Mar0s Mar0s

$btained

Full Mar0s Mar0s

$btained

At !nd of 1st

Semester

70 70

At !nd of "nd

Semester

70 70

Total 100 100

108 of the mar)s 10 + 10

1uestion #attern in .ritten e!a"ination of Periodical institutional *ssess"ent

!"e n'm*er #& 'esti#ns in eac" t"e#r$ ill *e 'r (4) "avin+ t"e ll#in+ ,istri*'ti#n

#& marks.

-. 1) One l#n+ essa$ t$pe 'esti#n (#'t #& t#) c#nsistin+ #& 24 small se+ments. arks r eac" se+ment ill *e in,icate, separatel$. arks ma$ *e 12.

-. 2) !# s"#rt essa$ t$pe 'esti#ns (#'t #& t"ree) c#nsistin+ #& 2 small se+ments an,

marks r eac" se+ment ill *e in,icate, separatel$. arks ma$ *e 14 ( x 2).-. ) 3#'r s"#rt n#tes (#'t #& &ive) arks ma$ *e 12 ( x 4).

-. 4) 3#'r s"#rt clinicall$ #riente, explanat#r$ n#tes (#'t #& 'r). arks ma$ 12 ( x 4)

Sche"e for #ractical e!a"ination of Periodical institutional *ssess"ent

1. 7&fi$e( identifications and crossing % 17 mar)s

". >indow dissection % 17 mar)s*. Surface mar)ing % ' mar)s

:. /maging % : mar)s

7. 2istology% 7 slides % 7 mar)s

'. Haoratory 9ote oo) % 7 mar)s

SJHHAB#S for First professional M.B.B.S. in Anatomy

8& 9ecture classes+


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ach lecture class shall be of one hour duration& Brea0 u# of only the i"#ortant

to#ics of the relevant #arts are given belo.&

*& Introduction: Total lecture classes - 21. Significance of anatomy in medical science, sudi$isions of the su6ect, 9omenclature ?

terminology &1(

". S)in ? sucutaneous tissue &1(

B&


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*. Structure of Hi$er ? Billiary apparatus &/ntra%? !xtra%hepatic( &*(

:. Portal $ein with porta%ca$al anastomosis &1(

7. Pel$ic iaphragm, Perineum &*(

'. Structure of spleen ? splenic circulation &1(

-. Structure ? lood supply of Kidney &*(. 9er$e supply of ladder, mechanism of micturition &1(

E. /nternal iliac artery ? its ranches &1(10. Hymphatics of adomen ? pel$is &1(

11. e$elopment of =./ Tract, rotation of gut and de$elopment of Hi$er ? Pancreas with

anomalies &7(

1". e$elopment of =enito%urinary system &-(

H& :hora!+ Total lecture classes- 17 (including Deelop!ent"1. Mechanism of Thorax ?


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B. =eneral Anatomy %"" 2. Thorax %1-

+. =eneral emryology %1' /. 2ead ? 9ec) %*0

. =enetics %7 @. +.9.S. %"0

!. Superior !xtremity %1-

F. /nferior !xtremity %11=. Adomen %1

II# Practical 5 7issection 5 7e"onstration 5 :utorial+

Brea0 u# of only the i"#ortant to#ics of the relevant #arts are given belo.+

Histology+ :otal ?@ classes of %A hours duration C4 hours (:o be taught during 2nd Se"ester)


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. Small 6oints of hand 1

•


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o #terus, 5agina, Female external genitalia, placenta *

o Sectional anatomy at TPP le$el, at H* le$el, +oronal

? Sagittal section of male and female pel$is :

o . Surface mar)ings 1

o .


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Suoccipital triangle &prosected part( 1

Sumandiular region "

Temporal and /nfratemporal fossa "

Temporomandiular 6oint 1

+ranial fossa and ;rit "

Pre$erteral region 1 Thyroid and parathyroid 1

Sagittal section of 2 ? 9, 9ose and nasal septum, Tongue

and ;ral +a$ity, Pharynx. Tonsil, Palate, Harynx Kidney from ac) "


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M$79 1US:8$;S (% st Prof MBBS)

*;*:$MD

First Pa#er

Time Three 2ours Full Mar)s 70

!"e &i+'res in t"e mar+in in,icate &'ll marks.

1. >rite any one of the following

&a( A young woman is suffering from a mammary gland infection with se$ere pain.escrie the 3uadrants of reast. #sing your )nowledge in anatomy, explain the

cause of mastitis, swelling and pain of reast. iscuss riefly the sets of axillary

lymph nodes. ":'C1"&( A young man was admitted in the hospital with indirect inguinal hernia.

>hat are the different types &congenital( of indirect inguinal hernia escrie the

oundary and contents of the inguinal canal. #sing your )nowledge in anatomy,

discuss the mechanism which normally pre$ent inguinal hernia. "':C1"

". iscuss riefly the following &any two( -x"C1:

&a( Following fracture dislocation of the right shoulder 6oint, a young adult patient

de$eloped Nwrist dropO.

>hich ner$e is li)ely to e damaged iscuss the distriution of the ner$e in different

segments of the upper lim. Mention the area of s)in of hand that would show

sensory loss. 171C-

&( A middle aged woman was admitted with a small painful swelling in her right groin,which was diagnosed as Nfemoral hernia. escrie the NcanalO in relation to the

femoral hernia. 2ow it could e distinguished anatomically from inguinal hernia and

why it is more common in female escrie the inferior !pigastric artery in the

context of femoral hernia. *""C-

&c( A young man was admitted with acute pain extending from the right loin to the right

groin. here does one loo) for the course of ureter in the D%ray plate !numerate the

position of the normal constrictions of the ureter, where a calculus is li)ely to e held

up. *""C-

*. >rite short notes on &any 'r ( *x:C1"

&a( !piploic foramen. &( Memranous urethra. &c( 9otochord.

&d( Special characteristics of the cla$icle. &e( e$elopment of pancreas

:. >rite rief explanatory notes, using your )nowledge in anatomy *x:C1"

&a( A new orn ay presents lea)age of urine through umilicus.

&( A chronic alcoholic adult male, suffering from cirrhosis of li$er, was admitted in the

hospital with outs of haematemesis &$omiting of altered lood(..

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&c( A$ascular necrosis of head following intracapsular fracture of the nec) of femur in

old age.

&d( /n carpal tunnel syndrome, there is urning pain sensation along the lateral three and

half fingers, ut no sensory impairment o$er the thenar eminence.

*;*:$MD

Second Pa#er

Time Three 2ours Full Mar)s 70


1. >rite any one of the following

&a( A young woman was admitted in the hospital with a large, solitary swelling infront of the nec), which mo$ed upward during swallowing. /t was diagnosed as a tumour

of the thyroid gland for which she was operated. But she de$eloped hus)y $oice. >hy

does the thyroid gland mo$e up with swallowing escrie the different parts, relationsand lood supply of the gland. #sing your )nowledge in anatomy, explain thede$elopment of hus)y $oice after thyroidectomy. ""C1"

&( An old woman with a history of trauma to the right eye, was complaining of

acute pain as well as loss of $ision of that eye. After careful examination it was found thatthere was anormal increase in intraocular pressure &glaucoma( due to ostruction to the

a3ueous humor drainage. >hat is a3ueous humor and what are its functions iscuss the

formation, circulation and drainage of the a3ueous humor along with its appliedimportance. 7-C1"

". iscuss riefly the following &any t#(

&a( A young woman was admitted in the hospital in unconscious state. /t was

diagnosed as a case of Nca$ernous sinus thromosisO, following a small ascess

on the Ndangerous area of the faceO. iscuss the communications of Face withca$ernous sinus. >hat are the other communications of the ca$ernous sinus

>hat do you mean y the dangerous area of the face "*"C-

&( Following a fracture in$ol$ing the spine of sphenoid, a patient de$elopedimpairment of taste sensation of tongue. >hich ner$e is in6ured in this case

iscuss riefly aout the ner$e. 1'C-

&c( A middle aged man was suffering from tuerculosis of lung, locali4ed to one ronchopulmonary segment. !numerate the Nronchopulmonary segmentsO of

lungs along with their anatomical characteristics and the clinical importance.*""C-

*. >rite short notes on &any 'r ( *x:C1"

&a( +oronary sinus.

&( Ma6or openings &normal( of the iaphragm.

&c( /nferior horn of lateral $entricle of rain.

1'


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&d( e$elopment of tongue.

&e( /nterior of larynx.

:. >rite rief explanatory notes, using your )nowledge of anatomy *x:C1"

A child inhaled a metal foreign ody. /n D%ray, it was found to e lodged in theright lung. >hy do foreign odies tend to e lodged in the right lung

&a( A neglected case of pharyngeal infection may spread to mastoid air cells.

&( A young woman with syringomyelia was found to ha$e impairment of

appreciation of pain and temperature of upper lims, ut preser$ation of

light touch sensation.

&c( Following a cerero%$ascular accident, a patient with right sided

hemiplegia could not understand the written or spo)en language.

EEEEEEEEEEEEEEEEEEEEEE

Sche"e for First Prof& MBBS !a"ination in Physiology

*& Written Pa#er

Pa#er 8+ 1& =eneral Physiology ". 9er$e muscle Physiology *.Blood

:. =./ System 7.


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1. 2aematology

Ma6or% &TH+T!+H+( % mar)s

Minor%&BT?+T2B8Blood group( %: mar)s

". /nstruments Mammalian exp.&ales, Hong extension, !+=, Spiro

meter, +harts, BM


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PHDS8$9$rite short notes on the following &an, our ( :x*

a( !xocytosis ( +hemoreceptors c( +onducting system of the heart

d( 5enous return e( Phagocytosis


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c( ;ral 5it. B1" cannot cure pernicious anemia.

d( #roilinogen is asent in complete iliary ostruction.

PHDS8$9$hat are the factors controlling spermatogenesis >hat is in

$itrofertili4ation 7"

( 2ow is sodium reasored in the renal tuule >hat is glomerulo%tuular

alance 7"

c( 9ame the photosensiti$e pigments in the retina. escrie the se3uence of

e$ents in$ol$ed in phototransduction in the retina. "7


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c( Brady)inesia occurs in Par)insonOs disease.

d( /nsulin lowers lood sugar le$el.

SD99*BUS for First #rofessional M&B&B&S& in Physiology including Bio#hysics

%&


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• 2aemostasis


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• 2ypoxia including high altitude physiology and acclimati4ation, asphyxia,

cyanosis, oxygen therapy and toxicity.

• !ffects of increased arometric pressure%nitrogen narcosis, high pressure

ner$ous syndrome, decompression sic)ness &+aissons disease(.

• Artificial respiration.

• Hung function tests.

@& 'ardiovascular syste"+ 22 hrs&

• Functional anatomy of heart

and lood $essels.

• Properties of cardiac muscle.

• ;rigin and spread of cardiac

impulse, heart loc), cardiac arrhythmias.

• !+= leads, principles of

normal recording, normal wa$es, ? their interpretations, electrical axis of

the heart including left and right axis de$iation, clinical uses of !+=.• +ardiac cycle Mechanical

e$ents, Pressure changes in atria, $entricles, aorta, pulmonary artery and

6ugular $ein. !nd diastolic $olume, !nd systolic $olume, !6ection fraction.

• 2eart sounds normal character,

physiological asis of splitting, murmur.

• +ardiac output efinition,

etermination, Factors regulating, 5enous return.

• Arterial pulse normal ?

anormal.

•

Physical principles go$erningflow of lood in heart ? lood $essels, laminar flow, turulent flow,


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=& ndocrine syste"+ 2 hrs&

• =eneral organi4ation of endocrine glands ? control system

• Mechanism of hormone action.

• Biosynthesis, regulation of secretion, transport, fate and actions of

hormones secreted from. 2ypothalamus, Pituitary, Thyroid, Adrenal

cortex, Adrenal medulla, Parathyroid &along with calcium metaolism( and

endocrine pancreas, importance to e gi$en to clinical conditions

associated with hypo and hyper functions of these glands.

& Re#roductive syste" % hrs&

• Sex differentiation and de$elopment of & !cretory Syste"+ %2 hrs&

o Functional anatomy of )idney, nephron%structure, parts, function, types.

o @uxtaglomerular apparatus autoregulation, peculiarities, measurements.

o


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• ;rgani4ation of ner$ous system, functional anatomy of rain and spinal

cord, neuron, neuroglia

• +ereral circulation, +SF, lood%rain arrier

• Synapse% types, properties, synaptic transmission, neurotransmitters

• .Sensory receptors classification, generator potential, properties,

•


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a( +ompound microscope. ( Preparation of lood film

c( Staining with HeishmanOs stain d( /dentification of lood cell

e( ifferential count of >B+ f( Total count of >B+.g( Total count of


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Practical +%@ hrs&

:utorial including


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-.4) 3#'r s"#rt clinicall$ #riente, explanat#r$ n#tes #n statements / anal$tical t$pe

#& 'esti#ns 12 arks (x4)

Ade3uate emphasis will e gi$en to 3uestions on applied aspects.

B& $ral56iva

i( Topics of 1st paper%10 mar)s ii( Topics of "nd paper%10 mar)s Total mar)s%"0.

7istribution of the to#ics during viva voce

:able %+ell structure, +ell memrane, Signal transmission, Mechanism of hormone

action, Biological ;xidation, oxidati$e phosphorylation, !n4ymes% classification, mode of

action, allosteric en4yme, +linical en4ymes, Functional proteins% haemogloins, myogloin,

collagen

:able 2 Medical physics% isotopes, radioisotopes, radioimmunoassay, !H/SA,+hromatography, +olorimetry, !lectrophoresis, Acid, Base, uffer, Acid%Base Balance, p2 of ody fluids, colloids, ;smosis, transport%acti$e, passi$e, facilitated, endocytosis, igestion

and asorption of foodstuffs

:able ?% Purines, Pyrimidines, Proteins, 5itamins, /norganic elements% their chemistry,

normal and anormal Metaolism

:able 4% Molecular iology, genetics, =ene expression, 9A ?


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-.) One s"#rt n#te t$pe 'esti#n #r explanat#r$ n#te t$pe 'esti#n (3#'r #'t #&

&ive). 12 arks (x4)

-.4) 3#'r s"#rt clinicall$ #riente, explanat#r$ n#tes #nstatemets / anal$tical t$pe #&'esti#ns 12 arks (x4)

SJHHAB#S ;F B/;+2!M/S


30/38

*( Simple uilding loc)sG organi4ation of macromolecules.'HM8S:RD $F 9868;< M*::RS

:( +arohydrates its nomenclature, classification with examples chemical structureof monosaccharides and disaccharides in Pyranose and Furanose form.

7( /somerism stereoisomers, optical isomers, epimers, anomens. Mutarotation,

specific rotation.'( =lycosidase lin)ageG deoxy and amino sugars and homopolysaccharides, their

chemical structures and importance.

-( +hemical structures of heteropolysaccharides, glycosaminoglycans and

glycoproteins.( +arohydrates in acterial cell wall and lood group sustances.

E( /nterpretation of chemical reactions of carohydrates.

10( +lassication of lipids. +hemical structure of simple lipids. 9omenclature ofsaturated and unsaturated fatty acids.

11( !ssential fatty acidsG /mportance of omega * fatty acidsG structure and functions of

prostaglandin, leucotrienes and thromoxanes.

1"( +lassification and structure of phospholipids. Surfactant. =lycolipids.1*( eri$ed lipids structure of cholesterol, steroid hormones, and ile acids.

1:( +haracteri4ation of lipids Saponification no. /odine no. Acetyl no. Acid no.,

Polens)i no.


31/38

**( Kinetics of en4ymes


32/38

7', 7- ? 7( Fate of glucose after asorption. =lycolytic pathway +hemical

structures of intermediates, allosteric control of )ey en4ymes, inhiitors, !nergy

production and hormonal control.

7E,'0( =lycogenesis and =lycogenolysis +o$alent modification of en4ymes,

2ormonal control, glycogen storage disease.

'1( +on$ersion of Pyru$ate to Acetyl coA. +ontrol of Pyru$ate dehydrogenase

complex.

'", '* ? ':( Tricaroxylic acid cycle +hemical structure of intermediates, Sites ofATP production, regulatory mechanism.

'7( 9ormal and anormal metaolism of Fructose and =alactose.

''( =luconeogenesis From Hactate, =lycerol and =lucogenic amino acids, control of

)ey gluconeogenetic en4ymes.

'-( Pentose phosphate pathway /mportance of generation of 9AP2, =lutathione

and red cell memrane integrity.

'( Formation of =lucuronic acid and its significance. /ts structural resemlance with

Ascoric acid.

'E ? -0( =lucose tolerance test oral and intra$enous, Procedure and interpretation.

=lycosuria, glycosylated haemogloin.

M:*B$98SM $F 98P87S

-1( igestion and asorption of fats Micelle formation,


33/38

',- ? ( +hemical structure, synthesis, secretion, transport and degradation of

insulin, mechanism of action. /nsulin receptors. /nsulin li)e growth factors.

E( Structure and mechanism of action of =lucagon.

M:*B$98SM $F PR$:8;S

E0( ietary protein, its iological $alue and digestiility coefficient. Proteinmalnutrition. !ssential amino acids.

E1( igestion of proteinsG asorption of amino acids, gama%glutamyl cycle.

E"( Fate of amino acid after asorption. Process of transamination


34/38

117( isorders of acid ase alance and its compensationG Anion gap.

11'( +hemistry and action of 5itamin A, 2yper$itaminosis.


35/38


36/38

H!SS;9 " To diagnose the case of chronic renal failure.

H!SS;9 "E To diagnose the case of haemolytic, hepatic, and ostructi$e 6aundice.

H!SS;9 *0 To diagnose the case of hyperlipoproteinemia.

H!SS;9 *1 To diagnose the case of renal glycosuria.

H!SS;9 *" To diagnose the case of diaetic )etoacidosis.

H!SS;9 ** To diagnose the case of myocardial infarction.

H!SS;9 *: To diagnose the case of star$ation )etoacidosis.

H!SS;9 *7 To diagnose the case of acidosis &metaolic and respiratory(.

H!SS;9 *' To diagnose the case of al)alosis &metaolic and respiratory(.

H!SS;9 *- To interpret the electrophoretogram of serum protein &normal and

anormal(

H!SS;9 * To determine the


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B8$'HM8S:RD

First Pa#er

Full Mar)s 70 Time Three 2ours


1. Answer any one of the following

a. >rite down the steps of determination of the primary structure of a

monomeric protein.1"

. escrie the process of digestion and asorption of triglyceride in the

intestine.

1"

". Answer any two of the followinga. efine Km and deri$e the rate of an en4yme cataly4ed reaction when

RSCKm, RSKm, RSUUKm. 1"""

. escrie the chemiosmotic hypothesis of oxidati$e phosphorylation with

the help of a diagram. "7

c. Mention the difference etween competiti$e and non%competiti$e

inhiition with Hinewea$er Bur) plot. "7

*. =i$e an explanatory note on the following &any four( *x:C1"

a( Acti$e site of an en4yme.

( atson%+ric) model of the 9A.

d( Pseudo nucleotide as coen4yme.

e( Fluid mosaic model of iomemrane.

:. !xplain the following statements ****

a( =lucose enhances the asorption of the 9a from the intestine.

( +oen4ymes are the co%sustrates in the en4ymes.

c( Hecithin is an amphipathic molecule.

d( /mmunogloulins are classified on the asis of type of hea$y chain present

in them.

*-


38/38


B8$'HM8S:RD

Second Pa#er

Full Mar)s 70 Time Three 2ours!"e &i+'res in t"e mar+in in,icate &'ll marks.

1( escrie only one of the following

a( escrie the glycolytic pathway in erythrocytes. +alculate the

total energy production when one more of glucose is utili4ed y

them. /ndicate the importance of ",* P= generated in this pathway. ""C1"

( escrie the formation of urea in the ody. Mention howammonia is disposed off y other methods. :C1"

"( escrie any two of the following

a( escrie the chemical composition and indicate the metaolism of

$ery low density Hipoprotein &5HH( with the help of a flow diagram.

"7C-

( >rite down the chemical structure and mechanism of action of

insulin. *:C-c( Mention the steps of heme iosynthesis with its control

mechanism. 7"C-

*( =i$e an explanatory notes on any four of the following ****C1"

a( =enetic code

(

1st prof mbbs regu

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