2013 10 10 - loinc and snomed ct
DESCRIPTION
Presentation by Daniel J. Vreeman, PT, DPT, MSc at the 2013 SNOMED CT Implementation Showcase in Washington, DC. Describes the RII-IHTSDO agreement (http://loinc.org/collaboration/ihtsdo/agreement.pdf) at a high level, brief introduction to LOINC, and how LOINC and SNOMED CT can be used together.TRANSCRIPT
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Daniel J. Vreeman, PT, DPT, MScAssistant Research Professor, Indiana University School of MedicineAssociate Director for Terminology Services, Regenstrief Institute, Inc
2013 SNOMED CT Implementation Showcase
LOINC and SNOMED CT
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Why am I here?
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Shared vision.Cooperation, not duplication.
photo via eherrera
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photo via lalalaleeuh
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photo via pennstatelive
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Origins of LOINCA universal catalog of laboratory and clinical observations
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photo via nosha McDonald et al. Canopy Computing: using the Web in Clinical Practice. JAMA. 1998;280(15):1325-1329.
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photo via nosha McDonald et al. Canopy Computing: using the Web in Clinical Practice. JAMA. 1998;280(15):1325-1329.
The rain forest canopy is a seamless web through which arboreal creatures efficiently
move to reach the edible fruits without any attention
to the individual trees.
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Fundamental challenge:Local systems have different ways of identifying the same concept. And, things that look alike aren’t the same.
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Same or Different?
Lab ATest Name: Lyme Disease Serology
Lab BTest Name: Lyme Disease Antibody
What you see in the test catalog
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Same or Different?
Lab ATest Name: Lyme Disease Serology
Measures: B. burgdorferi Ab IgG
Method: ELISA
Scale: quantitative
e.g.: Titer 1:40
Lab BTest Name: Lyme Disease Antibody
Measures: B. burgdorferi Ab IgM
Method: Immune blot
Scale: qualitative
e.g.: Positive
LOINC Code = 5062-5 LOINC Code = 6321-4
What you see in the test catalog
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More than Meets the Eye
photo via chadlewis
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Only way to corral the infinite indiosyncracies is
with standards
photo via pfarrell95
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Logical
Observation
Identifiers
Names and
CodesA universal code system that facilitates exchange,
pooling, and processing of results
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MEASUREMENTS
US“R”
photo via puuikibeach
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24467-3:Cells.CD3+CD4+:NCnc:Pt:Bld:Qn:
Anatomy of a LOINC TermCD3+�CD4+� (T4 helper) cells [#/�volume] in Blood
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24467-3:Cells.CD3+CD4+:NCnc:Pt:Bld:Qn:
24467-3 LOINC Code
Cells.CD3+CD4+
NCnc
Pt
Bld
Qn
Component
Property Measured
Timing
System
Scale
Method
Anatomy of a LOINC TermCD3+�CD4+� (T4 helper) cells [#/�volume] in Blood
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24467-3:Cells.CD3+CD4+:NCnc:Pt:Bld:Qn:
24467-3 LOINC Code
Cells.CD3+CD4+
NCnc
Pt
Bld
Qn
Component
Property Measured
Timing
System
Scale
Method
There are six major LOINC axes
Anatomy of a LOINC TermCD3+�CD4+� (T4 helper) cells [#/�volume] in Blood
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24467-3:Cells.CD3+CD4+:NCnc:Pt:Bld:Qn:
24467-3 LOINC Code
Cells.CD3+CD4+
NCnc
Pt
Bld
Qn
Component
Property Measured
Timing
System
Scale
Method
There are six major LOINC axes
Anatomy of a LOINC TermCD3+�CD4+� (T4 helper) cells [#/�volume] in Blood
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Born in 1994 by Regenstrief Institute.
Worldwide distribution at no cost.
Copyrighted, but open license.
Released twice per year.
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Born in 1994 by Regenstrief Institute.
Worldwide distribution at no cost.
Copyrighted, but open license.
Released twice per year.
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Born in 1994 by Regenstrief Institute.
Worldwide distribution at no cost.
Copyrighted, but open license.
Released twice per year.
It’s free, but invaluable.
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Born in 1994 by Regenstrief Institute.
Worldwide distribution at no cost.
Copyrighted, but open license.
Released twice per year.
It’s free, but invaluable.
![Page 27: 2013 10 10 - LOINC and SNOMED CT](https://reader035.vdocuments.net/reader035/viewer/2022081800/55cf9ba3550346d033a6d35b/html5/thumbnails/27.jpg)
Born in 1994 by Regenstrief Institute.
Worldwide distribution at no cost.
Copyrighted, but open license.
Released twice per year.
It’s free, but invaluable.
Just don’t use it to make another standard!
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If an observation is a question and the observation value isan answer…
LOINC provides codes for questions
Where needed, other vocabularies provide codes for answers
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Laboratory LOINC
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Clinical LOINC
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LOINC CollectionsPanels, forms, surveys, and other
patient assessments
photo via LuzA
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Standardized Assessments and Collections
Vreeman DJ, McDonald CJ, Huff SM. Representing patient assessments in LOINC®. AMIA Annu Symp Proc. 2010;832-836. PMID: 21347095 .
Vreeman DJ, McDonald CJ, Huff SM. LOINC® - A Universal Catalog of Individual Clinical Observations and Uniform Representation of Enumerated Collections. Int J Funct Inform Personal Med. 2010;3(4):273-291.
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0
10,000
20,000
30,000
40,000
50,000
60,000
70,000
80,000
4/24/1
995 | 1.0
5/24/1
995 | 1.0
a
6/23/1
995 | 1.0
b
6/28/1
995 | 1.0
c
7/14/1
995 | 1.0
d
9/15/1
995 | 1.0
e
12/21/1
995 | 1.0
f
4/28/1
996 | 1.0
g
8/29/1
996 | 1.0
h(2)
12/3/1
996 | 1.0
h(3)
1/8/1
9997 | 1.0
i
10/9/1
997 | 1.0
j-a
5/1/1
998 | 1.0
k
2/12/1
999 | 1.0
l
7/23/1
999 | 1.0
m
8/6/1
999 | 1.0
ma
2/4/2
000 | 1.0
n
6/13/2
000 | 1.0
0
1/1/2
001 | 2.0
0
1/31/2
001 | 2.0
1
7/1/2
001 | 2.0
3
1/1/2
002 | 2.0
4
2/1/2
002 | 2.0
5
2/19/2
002 | 2.0
6
8/1/2
002 | 2.0
7
9/1/2
002 | 2.0
8
5/1/2
003 | 2.0
9
10/1/2
003 | 2.1
0
1/1/2
004 | 2.1
1
2/1/2
004 | 2.1
2
12/1/2
004 | 2.1
3
12/1/2
004 | 2.1
4
6/1/2
005 | 2.1
5
12/1/2
005 | 2.1
6
6/1/2
006 | 2.1
7
12/21/2
006|2.1
9
6/21/2
007|2.2
1
12/03/2
007|2.2
2
7/10/2
008|2.2
4
1/10/2
009|2.2
6
07/06/2
009|2.2
7
12/30/2
009|2.2
9
2/26/2
010|2.3
0
6/15/2
010|2.3
2
12/29/2
010|2.3
4
06/30/2
011|2.3
6
12/30/2
011|2.3
8
6/30/2
012|2.4
0
12/30/2
012|2.4
2
06/29/2
013|2.4
4
LOINC Codes
Only Lab LOINC Codes
LOINC Codes Over Time by Release
laboratory terms onlynot a lab “cliff”, just no data available
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Lots Cooking…Always more lab tests
Genetic reporting
Lots of survey instruments, forms, and assessments
More radiology reports
Structured document titles
…
photo via liber
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Data standards are like telephones.
They require a critical mass of users before they become useful.
photo via iboy_daniel
- Clem McDonald, MD 1998
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26,000+ users in 155 countries
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0
5,000
10,000
15,000
20,000
25,000
6/1/08
12/1/
08
6/1/09
12/1/
09
6/1/10
12/1/
10
6/1/11
12/1/
11
6/1/12
12/1/
12
6/1/13
loinc.org members
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0
5,000
10,000
15,000
20,000
25,000
6/1/08
12/1/
08
6/1/09
12/1/
09
6/1/10
12/1/
10
6/1/11
12/1/
11
6/1/12
12/1/
12
6/1/13
loinc.org members
18 new members per day550 new members per month
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0
5,000
10,000
15,000
20,000
25,000
6/1/08
12/1/
08
6/1/09
12/1/
09
6/1/10
12/1/
10
6/1/11
12/1/
11
6/1/12
12/1/
12
6/1/13
loinc.org members
18 new members per day550 new members per month
Doubled in 19 months!
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LOINC Translators
22 organizations. Currently translations into 17 variants of 11 languages
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Vreeman DJ et al. Enabling international adoption of LOINC through translation. J Biomed Inform 2012 Aug;45(4):667-73.doi: 10.1016/j.jbi.2012.01.005. Epub 2012 Jan 21. PubMed PMID: 22285984
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Adopted as National StandardAustralia
Austria
Belgium
Brazil
Canada
Cyprus
Estonia
Finland
France
Germany
Iceland
Mexico
Mongolia
The Netherlands
New Zealand
Philippines
Portugal
Rwanda
Slovakia
Slovenia
Spain
Thailand
Turkey
United States
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Large Implementations
SIGA Saúde project
7+ Provincial systems in Canada
15+ Regional Health Information Exchanges in Spain
ePSOS
Assistance publique - Hôpitaux de Paris
Hong Kong Hospital Authority
Philippine Health Insurance Corporation
InFSE Project in 5 regions in Italy (LOINC Italia)
Many more...
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In USA, major driver of eHealth standards adoption is
EHR Incentive Program
a.k.a. “Meaningful Use”
Blumenthal D, Tavenner M. The "meaningful use" regulation for electronic health records. N Engl J Med. 2010 Aug 5;363(6):501-4. Epub 2010 Jul 13. PubMed PMID: 20647183.
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Stage 2starting 2014
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LOINC adopted for:1. View, download, transmit data to third party2. Cancer case reporting to state registry3. Send/receive electronic lab results in
ambulatory settings4. Provide a care summary at care transition5. Provide clinical summaries for patients6. Submit reportable lab results to public health
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Use in Quality Measures
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LOINC Adopted ForPatient Characteristics
[Non-lab] Diagnostics studies
Patient experience
Family history
Functional status
Health record component
Interventions (that produce an assessment or measured results)
Laboratory tests
Physical exam
Patient preference
Risk evaluation
System resources (healthcare resources)
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You too can fall for LOINC
photo via mccaughan
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Agreement paves the way for new shared benefits (down the road)
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4 Main DeliverablesMapping LOINC Parts to SNOMED CT concepts
Mapping existing SNOMED CT Observables to LOINC terms
LOINC terms associated with post-coordinated expressions
LOINC terms with categorical answer values linked to SNOMED CT answers
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Approach
LOINC Terms
LOINC Parts
Add Missing Content
Existing SNOMED CT Observable entities and Evaluation procedures
SNOMED CT Expressions
SNOMED CT Attribute values
mapexpression association
map
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LOINC Terms
LOINC Parts
Add Missing Content
Existing SNOMED CT Observable entities and Evaluation procedures
SNOMED CT Expressions
SNOMED CT Attribute values
mapexpression association
map
Maps between LOINC Parts and SNOMED CT - add stuff where needed
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LOINC Terms
LOINC Parts
Add Missing Content
Existing SNOMED CT Observable entities and Evaluation procedures
SNOMED CT Expressions
SNOMED CT Attribute values
mapexpression association
map
LOINC Terms represented in SNOMED CT as “expressions”
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How We’ll ProceedPragmatically, not perfectly
Starting with these domain areasLaboratory
Including discrete orders and observations and panel names for orders (excluding panel structure)
Anthropomorphic measurements and evaluations
Vital signs and physiological measurements
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We’ll need some patience from users
photo via blauertm
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Using LOINC and SNOMED CT Together
photo via scarlatti2004_images
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Electronic Lab Reporting to Public Health
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Lab to Public Health Reporting
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RCMTReportable Condition Mapping Table
Links reportable conditions to associated LOINC laboratory tests and SNOMED results
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Acute poliomyelitis (disorder)SCTID: 398102009
Lab Test Name ( from LOINC)40709-8 Polio virus Ab [Units/volume] in Cerebral spinal fluid
16284-2 Polio virus Ab [Units/volume] in Serum
42980-3 Polio virus Ab [Titer] in Serum
27261-7 Polio virus Ab [Titer] in Serum by Complement fixation
60546-9 Polio virus identified [Type] in Isolate by Organism specific culture
53645-8 Polio virus identified in Stool by Organism specific culture
...lots more...
Lab Test Result (from SNOMED CT)44172002 Human poliovirus (organism)
22580008 Human poliovirus 1 (organism)
55174004 Human poliovirus 2 (organism)
16362001 Human poliovirus 3 (organism)
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Overhage JM, Suico J, McDonald CJ. Electronic laboratory reporting: barriers, solutions and findings. J Public Health Manag Pract. 2001 Nov;7(6):60-6. PubMed PMID: 11713754.
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4X greater detection rate than MD-based reporting.
Same day versus 2-5 day reporting.
Overhage JM, Suico J, McDonald CJ. Electronic laboratory reporting: barriers, solutions and findings. J Public Health Manag Pract. 2001 Nov;7(6):60-6. PubMed PMID: 11713754.
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Overhage JM, Suico J, McDonald CJ. Electronic laboratory reporting: barriers, solutions and findings. J Public Health Manag Pract. 2001 Nov;7(6):60-6. PubMed PMID: 11713754.
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Newborn Screening
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newbornscreeningcodes.nlm.nih.gov
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The Future
Great Scott!photo via JD Hancock
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24467-3:Cells.CD3+CD4+:NCnc:Pt:Bld:Qn:
LOINC SNOMED CT
Maps and ExpressionsCD3+�CD4+� (T4 helper) cells [#/�volume] in Blood
Cells.CD3+CD4+T lymphocyte positive for
both CD3 antigen and CD4 antigen (cell)
NCncNumber concentration
(qualifier value)
PtSingle point in time
(qualifier value)
Bld Blood specimen (specimen)
QnQuantitative (qualifier
value)
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Expression Associations SNOMED Observable Model for Qualities
Cells.CD3+CD4+:NCnc:Pt:Bld:Qn
Scale: 30766002
Inheres in: 119297000
Process duration: 123029007
Towards: 115396002
Property Type: 118550005
Incoming LOINC Code 24467-3 means...
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Now, you can use the SNOMED CT hierarchy for queries, etc...
SNOMED CT Concept
Body structure
Anatomical or acquired body structure
Anatomical structure
Body system structure
Structure of hematological system
Blood cell
Leukocyte
Peripheral blood mononuclear cell
Lymphocyte
T lymphocyte
T lymphocyte positive for CD4 antigen
T lymphocyte positive for both CD3 antigen and CD4 antigen
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Common Questions
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When will all this be done?
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Remember the request for patience?
Starting first with the most common lab tests (LOINC Top 2000) and components from Microbiology and Chemistry
Alpha (~ March 2014)
Preview release (~ July 2014)
Initial release (~Jan 2015)
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Should I stop using LOINC?
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Of course not!IHTSDO endorses the use of
LOINC Codes forrepresentation of orders and
observations in countries where LOINC has been adopted.
Cooperation Agreement between the International Health Terminology Standards Organisation and the Regenstrief Institute, Inc. July 2013
More reasons now than ever!
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IHTSDO and RII both endorse the statement that, LOINC provides codes that represent the names of information items (e.g. questions) and SNOMED CT provides
codes that may represent nominal and ordinal values (e.g. answers) for these
named information items.
Cooperation Agreement between the International Health Terminology Standards Organisation and the Regenstrief Institute, Inc. July 2013
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Will IHTSDO keep making SNOMED CT Observables?
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Yes. But like we said, LOINC has >70,000 of them and we’re committed to minimizing duplication.
Cooperation Agreement between the International Health Terminology Standards Organisation and the Regenstrief Institute, Inc. July 2013
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Yes. But like we said, LOINC has >70,000 of them and we’re committed to minimizing duplication.
Within the scope of this Agreement, IHTSDO will not add new SNOMED CT Concepts that are
subtypes of “Observable Entity” or “Evaluation Procedure” within the Cooperative Areas, except
where one of the following conditions applies:
Cooperation Agreement between the International Health Terminology Standards Organisation and the Regenstrief Institute, Inc. July 2013
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A specific requirement for such an addition has been formally submitted to the IHTSDO by two or more IHTSDO Members, and the additional
concept has been modeled and reviewed in line with SNOMED CT editorial guidelines.
Requests for additions derived from lists of LOINC Terms, will not be accepted without
special permission from RII.
Condition 1
Cooperation Agreement between the International Health Terminology Standards Organisation and the Regenstrief Institute, Inc. July 2013
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Or
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A LOINC Term cannot be sufficiently specified by a post-coordinated expression based on the SNOMED CT Concept model, and the additional concept has been modeled and reviewed in line
with SNOMED CT editorial guidelines.
IHTSDO will seek to modify the SNOMED Observable Model to accommodate Observable Entities that measure the sum of 2 or more analyses and other changes to
minimize the need to invoke this clause.
Condition 2
Cooperation Agreement between the International Health Terminology Standards Organisation and the Regenstrief Institute, Inc. July 2013
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Happy LOINCing!photo via ryarwood
The Race is On!