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ANNUAL REPORT

Clinical & Chemical Pathology

Department

Reporting period: January 2013– December 2013

Chair of the Department: Prof. Dr. Mervat El-Ansary

Prepared by: A. Prof. Nelly Abulata

A. Prof. of Clinical Pathology

Edited by: A. Lecturer Cherifa Tarek

A. Lecturer of Clinical Pathology

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Table of Contents

I. LETTER FROM THE CHAIR…………………………………………………………………….3 II. CLINCHEM AT A GLANCE……………………………………………………………………...5

1. About Us.…………………………………….……………………………………………..…...6 2. Role of the Department………….…………………..…………………………………..………7

III. FACULTY & STAFF….………………………………………………………………………..….8 1. Manpower Overview……………………….……….……………………………………………....9 2. Administrative Roster……………………….……….…………………………………………….10 3. Promotions and Appointments..……………….…………………………………………………..14 IV. TEACHING, TRAINING & EXAMINATION……………….……….……………………….15 1. Teaching & Training…………………………..……………..…………...………………………...16 2. Examination……………………….……….………………………………………………………17 V. RESEARCH & SCIENTIFIC ACTIVITIES…..………………………..….……………..……….18 1. The Department’s Research Plan…………………………..……………..…………...…………….19 2. Research Projects……….……………………….……….…………………………………………19 3. Journal Editorialships/Editorial Reviewers…………………………………….……….…...………19 4. Associations/Societies/Organization/ Committee Memberships……………………….………..…21 5. Publications……………………….……….………………………………………………………..24 6. Training/Courses/ Workshops Activities..………………………………………………………….27 7. Conference Activities...……………………………………………………………………………...28 VI. LABORATORY SERVICES………………………..….............................................................................33 1. Background Information…………………………………..……………………………….………..34

2. Annual Productivity……………………………………………..…………………………………...34

3. Blood Bank Services…………………………………………………..………………………….…..35 4. New tests introduced……………………………….…………………………………….……..……35 5. New techniques introduced……………………………….…………………………………….……36 6. New Lab……………………………………………………………………………………………...36 6. Others………………………………………………………………………………………………..38

VII. COMMUNITY SERVICE………………………………………………………………………....39

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I- LETTER FROM THE CHAIR:

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2013 encompassed many changes in Health Care. Working together with 283 faculty members, nearly 52 residents and several hundred Technologists & Technicians, nurses, administrators, and staff who make up the department, we have made rapid strides toward achieving those goals. This year we achieved an overall annual productivity of 5,521,930 tests, which could not have been reached, without our dedicated manpower (1,215 employees). With the appointment of new Heads of Laboratories, Heads of Units and Laboratory Directors and with the creation of an Executive Committee, the Department now has the infrastructure it needs to continue its path.

All through 2013, we continued a steady expansion in our three major missions; Laboratory Services, Teaching & Training and Research Activities. In the Laboratory service arena, we continued to push ahead with the implementation of Quality Assurance System at our Lab Branches. The New ER Lab at the New ER Hospital has opened and in addition to a new ER Blood Bank. The Japenese Lab underwent major changes and developments in its infrastructure & we expect it to further blossom in 2014.

Teaching & Training activities also remained very strong. Our goal is to train Clinical & Chemical Pathologists who will make a difference whether they chose a career path in academic medicine or in clinical practice. In addition to the pre– Master & pre-Doctorate teaching & training programs we now offer regular training to the Egyptian Fellowship Board Students in addition to 2 weeks condensed summer training program to undergraduate students. We continued the partnership we formed last year with the Training Program in Regenerative Medicine (TPRM) of the University of Toronto in Canadawhich introduced Regenerative Medicine in Cairo University. TPRM offered regular weekly lectures from September 2013 to April 2014 that will be webcasted from Toronto and were displayed at an auditorium in the Learning Resource Center (LRC) in Kasr Al-Ainy. This was the a first building block for the Regenerative Medicine Unit that was inaugurated in 2013 that will hopefully start running by mid 2014.

In the Research arena, several research projects were funded by the faculty under the roof of the 2-5yr plan for the Research activities of the Department, which involved all 4 specialties of the Department (Hematology, Immunology, Microbiology and Chemistry. As for our Faculty publications, over 50 articles were published in international Journals, several of which were in the high impact journals. Our yearly ClinChem Conference legacy was held in April 2013 under the title Is Regenerative Medicine a hope or hype? That was held at the Learning Resource Center at Kasr Al-Ainy Faculty of Medicine. Another source of pride was the work of our Faculty Staff in a collaborative initiative with the Egyptian Society of Laboratory Medicine in organizing ESLM 2013 Conference, which was held at the Cairo International Conference Center in April 2013. In summary, the Department remains strong and undergoing carefully planned incremental growth, reflecting both our role in academia and in Laboratory service. With the opening of the the new Labs and units we look forward to gradual recruitment of several more staff and also to working closely with all of our other colleagues in the Faculty and Hospital to build our research, teaching and clinical enterprise in a fashion that melds with programmatic directions of the University as a whole. Prof. Dr. Mervat El-Ansary Chair, Clinical and Chemical Pathology Department

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II- CLINCHEM DEPARTMENT AT A GLANCE:

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1- ABOUT US

a. Mission “Is to provide excellence in Laboratory services, Teaching, Training and Research activities”.

b. Vision We aspire to be recognized as an Academic Department of excellence to support and enhance the mission and vision of Kasr Al-Ainy Faculty of Medicine, Cairo University.

c. Objectives 1. To provide excellent laboratory medicine services for the patients of Kasr Al-Ainy Hospital

in a timely & professional manner.

2. To provide an atmosphere of respect for our staff while encouraging continued personal

growth, education and development.

3. To provide excellent teaching to a broad spectrum of health care professionals, health

care workers and Lab personnel in conjunction with The University.

4. To provide the physical facilities and atmosphere where research activities can flourish, in

collaboration with Kasr Al-Ainy Faculty of Medicine and other affiliated institutions.

5. To promote health, treatment and prevention of disease in the diverse population which

we serve.

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2- ROLE OF THE DEPARTMENT

a. Teaching & Training:

The Department is committed to providing strong and balanced Teaching and Training

programs mainly to Postgraduate Students, principally in the Master and Doctorate degrees

in Clinical and Chemical Pathology tailored to each student subspecialty (Hematology,

Immunology, Microbiology or Chemical Pathology). The Department is also partly involved in

the Teaching & Training of Postgraduate Students of other Departments enrolled in

Doctorate, Master & Diplomas degrees in addition it provides instructional courses to the 6th

year students. And for the last 2 summers it offered a condensed 2 weeks training course to

undergraduate students.

b. Research Activities:

The Research Faculty members within the Department are nationally recognized. The

Research ranges from clinical to basic Research, with an emphasis on Hematologic

Malignancies, Virology & Molecular Genetics.

c. Laboratory Services:

The Department offers Clinical and Chemical Laboratory services designed to meet the

needs of physicians, & patients. The Department has 2 Main Labs at Al-Manial Hospital, a

Lab. in each of the following Hospitals; the Specialized Hospital (4th Floor), the Internal

Medicine Hospital, the Pediatric Japanese Hospital, the Pediatric Abou Elrish Hospital, King

Fahd Hospital, the French Hospital, the new Lab at the Maternity Hospital, in addition to

Emergency Labs that offer the Lab services during the evening and night shifts. The

Department is also responsible for the Technical supervision of the Blood Bank and recently

has recently become responsible for the Lab at the Clinical Oncology and Nuclear Medicine

Department.

Laboratory

Services Research

Teaching

&

Training

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III. FACULTY & STAFF

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1- OVERVIEW OF MAN POWER

The Department has a total manpower of 1215 employees. This comprises:

369 Doctors; 283 Faculty members, 34 Specialists & 52 Residents

372 Technologists & Technicians

60 Nurses

199 Administration

65 Cleaners

283

34

52

Doctors

Faculty Staff

Specialists

Residents

369 372

60

199

65

0

50

100

150

200

250

300

350

400

Doctors Technologists &Technicians

Nurses Adminstration Cleaners

Human Resources

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2. ADMINISTRATIVE ROSTERS: a. Chair of the Department: Prof. Dr. Mervat El-Ansary b. Deputies:

i. Deputy for Examination, Staff Positioning/ Relocation Affairs: Prof. Dr. Hanaa Arnaout

ii. Deputy for Teaching, Training Affairs: Prof. Dr. Hala Farawela iii. Deputy for Scientific Research Development Affairs: Prof. Dr. Hala Gabr.

c. Seniors of each Division: i. Senior Hematologist: Prof. Dr. Hanaa Arnaout ii. Senior Immunologist: Prof. Dr. Inas Rafaat iii. Senior Microbiologist: Prof. Dr. Amani El Kholy iv. Senior Chemical Pathologist: Prof. Dr. Fatma El Mougy

d. Advisors to the Chair of the Clinical & Chemical Pathology Department:

i. Hematology Advisor: Prof. Dr. Azza Mostafa ii. Immunology Advisor: Prof. Dr. Safaa Al-Karaksy iii. Microbiology Advisor: Prof. Dr. Soheir Helal iv. Chemical Pathology Advisor: Prof. Dr. Sara AlKatib

e. Secretary General of the Council of the ClinChem Department: Dr.

Nelly Abulata

Chair of the Clinical & Chemical Pathology Dept

Deputy for Examination &

Positioning/ Relocation

Affairs

Team with representatives of

all specialties

Deputy for Teaching,

Training Staff Affairs

Team with representatives of

all specialties

Deputy for Scientific

Research Affairs

Team with representatives of

all specialties

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f. Technical Development Officer: Dr. Nelly Abulata

g. Committees (2012-2013)

i. Executive Committee for Laboratory Services:

Head of the Committee: Prof. Dr. Mervat El-Ansary

Moderator of the Committee: Dr. Nelly Abulata

Members of the Committee:

Main Lab at Manial Hospital

Lab Head of

Lab.

(Technical)

Lab Director

(Administrative)

Head of

Hematology

Unit

Head of

Immunology

Unit

Head of

Genetics

unit

Head of

the

Molecular

Unit

Head of

Microbiology

Unit

Manial

Clinical

Pathology

Lab.

Prof. Dr.

Hala

Sheebah

Dr.

Hanan A.

Moneim

Prof. Dr.

Hala

Sheebah

Prof. Dr.

Noha

Shaheen

Prof. Dr.

Hala

Farawela

Prof. Dr.

Mona

Salah

Prof. Dr.

Mona Wassef

Lab Head of Lab.

(Technical)

Lab Director

(Administrative)

Head of

Trace

Elements

Unit

Head of

Chemistry

Routine Unit

Head

of Proteins Unit

Head

of Hormones

Unit

Manial

Chemical

Pathology

Lab.

Prof. Dr.

Fatma El-

Mougy

Prof. Dr.

Badawy Al-Khouly

Prof. Dr.

Badawy Al-

Khouly

Prof. Dr. Lamia

Mansour

Prof. Dr. Sahar

Abdel-Atty

Prof. Dr.

Nadida Gohar

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Other Hospital based labs

Laboratory Head of Lab.

(Technical)

Lab Director

(Administrative)

Head of

Hematology

Head of

Immunology

Head of

Microbiology

Head of

Chemical

Pathology

Internal

Medicine

Hospital Lab.

Prof. Dr.

Sahar Kamal

Prof. Dr.

Sahar Kamal

Prof. Dr.

Sahar Kamal

Prof. Dr.

Nancy El-

Guindy

A. Prof. Dr.

Amaal Abdou

Japanese

Hospital Lab.

Prof. Dr.

Hanaa

Arnaout

Prof. Dr.

Iman Mansour

Prof. Dr.

Hanaa

Arnaout

A. Prof. Dr.

Reem Jan

Prof. Dr.

Mona Mohie

El-Din

Prof. Dr. Amal

AbdelWahab

Abou-Elrish

Mounira

Hospital Lab.

Prof. Dr. Azza

Abou

El-Enian

Prof. Nesrine

ElGharbawi

Prof. Dr. Hala

Gabr

Prof. Hend

ElSherbiny

Prof. Dr.

Maha Gaafar

Prof. Dr.

Heba Sharaf

El-Din

Specialized

Hospital Lab.

(4th floor)

Prof. Dr.

Taysir Eyada

Prof. Dr.

Hoda Sadek

A. Prof. Dr.

Dina Rasheed

Prof. Dr.

Mervat Gabr

Prof. Dr.

Amed ElTawil

French

Hospital Lab.

Prof. Dr.

Laila Hegazy

Dr. Hanan

Ibrahim

Prof. Dr.

Naguib Zoheir

Prof. Dr.

Nancy El-

Guindy

Prof. Dr.

Neven

ElRasheedy

Prof. Dr. Ola

ElSissi

King Fahd

Hospital Lab.

A. Prof. Dr. Manal Kamal

Psychiatric

Hospital Lab.

Prof. Dr. Badawy Al-Khouly

New ER

Hospital Lab

Prof. Dr. Badawy Al-Khouly

Maternity

Hospital Lab.

Prof. Dr. Iman Mandour Prof. Dr.

Hanan Nour

Sharm

ElSheikh Int.

Hosp.

Assistant Prof. Mohamed Shehata

Blood Bank Prof. Dr.

Mervat Al-

Ansary

Dr. Sahar Azab

Unit Closed and work is referred to the main

lab or nearest specialized lab

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i. Executive Committee for Blood Bank Affairs:

Head of the Committee: Prof. Dr. Mervat El-Ansary

Members of the Committee:

Director General of Hospitals: Prof. Dr. Alaa Maher

Deputy Director General of Hospitals: Prof. Dr. Ahmed Taha

Director of ER Hospital: Prof. Dr. Hesham Abou Eisha

Director of OR: Prof. Dr. Mohamed Hassan

Deputy Director of ER Hospital for Critical Care: Prof. Dr.Hesham Khedr

Chair of the Department & Head of the Blood Bank: Prof. Dr. Mervat Al-Ansary

Moderator: Prof. Dr. Ossama Khalafalla

Blood Bank Director: Dr. Sahar Azab

ii. Ethical Committee for Scientific Research:

Head of the Committee: Prof. Dr. Azza Mostafa

Members of the Committee:

Hematology: Prof. Dr. Hanaa Arnaout, Prof. Dr. Samia Rizk

Immunology: Prof. Prof. Dr. Tagrid Gafar, Dr. Mervat El-Ansary.

Chemical Pathology: Prof. Dr. Fatma El-Mougy, Prof. Dr. Hazem Abou

Youssef

Microbiology: Prof. Dr. Amani El-Kholy, Prof. Dr. Mona Wassef

iii. Quality Assurance Committee for Laboratory Service

Head of the Committee: Prof. Dr. Mervat El-Ansary

Project Leader: Consultant Dr. Ola Khashaba.

Team Members: The Heads of the Hematology, Immunology, Microbiology and

Chemical Pathology Department have nominated members of the teams.

iv. Quality Assurance Committee for Education

Head of the Committee: Prof. Dr. Mervat El-Ansary

Leader Prof. Dr. Shereen Mahmoud Team Members: The Heads of the Hematology, Immunology, Microbiology and

Chemical Pathology Department have nominated members of the teams.

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3. Promotions and Appointments

a. Promotions

Promoted to

Professor

Promoted to

Assistant

Professor

Promoted to

Lecturer

Promoted to

Assistant

Lecturer

i. A. Prof. Dina

ElAbd

ii. A. Prof. Noha

Shaheen

iii. A. Prof. Doha

AbdelHamid

iv. A. Prof. Marianne

Fathy

v. A. Prof. Aya

Nassef

i. Dr. Reham

Zeyada

ii. Dr. Nadia

Sewelam

iii. Dr. Shahira

Anis

iv. Dr. Nevine

Bahaa

v. Dr. Nelly

Abulata

i. Dr. Ahmed

Abdelhafez

ii. Dr. Reem Mostafa

iii. Dr. Mai Sherief

iv. Dr. Rehab

ElHusseiny

v. Dr. Alaa Afifi

i. Dr. Noha Salah

Eldin

ii. Dr. Mona Hazem

iii. Dr. Amira Farouk

iv. Dr. Radwa

Marawan

v. Dr. Mahitab

AbdelKawy

vi. Dr. Lamis Samy

vii. Dr. Salwa Khedr

viii. Dr. Nouran

Momen

ix. Dr. Maysa

Ibrahim

x. Dr. Heba

AbdelRahman

xi. Dr. Sherifa Tarek

xii. Dr. Rania Essam

xiii. Dr. Heba

Adel

xiv. Dr. Nashwa

Reda

xv. Dr. Dina Ezzat

xvi. Dr. Alia

ElDash

b. Appointments as Demonstrators: Dr. Reem Khalid

Dr. Ragda Taha

Dr. Heba ElGohary

Dr. Lamia Hany

Dr. Hend Tameem

Dr. Menatallah Mohamed

Dr. Aisha Omar

Dr. Amira Kotb

Dr. Zainab Sayed

Dr. Amal Bahgat

Dr. Amira ElSayed

Dr. Mariam Baligh

Dr. Shaima Mahmoud

Dr. Alaa Mohamed

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IV. TEACHING, TRAINING & EXAMINATION

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1. Teaching & Training a. Undergraduates

Clinical & Chemical Pathology curriculum teaching to the 6th year Students

Summer Training Programs to Undergraduate Students

b. Postgraduate Clinical and Chemical Pathology Degrees

Master Degree of Clinical & Chemical Pathology- First Part (Hematology)

Master Degree of Clinical & Chemical Pathology- First Part (Immunology)

Master Degree of Clinical & Chemical Pathology- First Part (Microbiology)

Master Degree of Clinical & Chemical Pathology- First Part (Chemical

Pathology)

Master Degree of Clinical & Chemical Pathology- Second Part (Hematology)

Master Degree of Clinical & Chemical Pathology- Second Part (Immunology)

Master Degree of Clinical & Chemical Pathology- Second Part (Microbiology)

Master Degree of Clinical & Chemical Pathology- Second Part

(Chemical Pathology)

Of other Specialities

Master Degree of Clinical Hematology

Master Degree of E.N.T

Master Degree of Internal Medicine

Master Degree of Physiology

Doctorate Degree of Clinical & Chemical Pathology (Hematology)

Doctorate Degree of Clinical & Chemical Pathology (Immunology)

Doctorate Degree of Clinical & Chemical Pathology (Microbiology)

Doctorate Degree of Clinical & Chemical Pathology (Chemical Pathology)

Doctorate Degree of Andrology

Doctorate Degree of Pediatrics

Doctorate Degree of Critical Care

Doctorate Degree of Clinical Hematology

c. Others Weekly Seminars

o Immunology: Every Sunday of the week

o Hematology: Every Monday of the week

o Chemical Pathology: Every Monday of the week

o Microbiology: Every Tuesday of the week

Egyptian Fellowship Board Training Program

House Officers Training Program

Faculty of Nursing Teaching & Training Program

Nursing School Teaching & Training Program

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2. Examinations (Written, Oral, Practical)

a. Undergraduates 6th year Clinical & Chemical Pathology exam

b. Postgraduate Clinical and Chemical Pathology Degrees

Master Degree of Clinical & Chemical Pathology- First Part (Hematology)

Master Degree of Clinical & Chemical Pathology- First Part (Immunology)

Master Degree of Clinical & Chemical Pathology- First Part (Microbiology)

Master Degree of Clinical & Chemical Pathology- First Part (Chemical

Pathology)

Master Degree of Clinical & Chemical Pathology- Second Part (Hematology)

Master Degree of Clinical & Chemical Pathology- Second Part (Immunology)

Master Degree of Clinical & Chemical Pathology- Second Part (Microbiology)

Master Degree of Clinical & Chemical Pathology- Second Part

(Chemical Pathology)

Of other Specialties

Master Degree of Clinical Hematology

Master Degree of E.N.T

Master Degree of Internal Medicine

Master Degree of Physiology

Doctorate Degree of Clinical & Chemical Pathology (Hematology)

Doctorate Degree of Clinical & Chemical Pathology (Immunology)

Doctorate Degree of Clinical & Chemical Pathology (Microbiology)

Doctorate Degree of Clinical & Chemical Pathology (Chemical Pathology)

Doctorate Degree of Andrology

Doctorate Degree of Pediatrics

Doctorate Degree of Critical Care

Doctorate Degree of Clinical Hematology

c. Others

Faculty of Nursing Teaching & Training Program

Nursing School Teaching & Training Program

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V. RESEARCH & SCIENTIFIC ACTIVITIES

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1. The Department’s Research Plan

a. Project Profile: The aim of this project is to develop a plan for the Research

activities of the Department over the coming 2-5 yrs (2009- 2013), which will involve all the specialties of the Department. The project will hopefully lead to the international recognition of the Department that will in turn participate in the International recognition of Kasr Al-Ainy Faculty of Medicine.

b. Project starting date: 27/08/09

c. Project structure:

i. Project Leader: Prof. Dr. Ali Shams El-Din

ii. Research Officer: Prof. Dr. Hala Gabr

iii. Project Team Members: Prof. Azza Mostafa, Prof. Taghrid Gaafar, Prof.

Amani El-Kholy, Prof. Fatma El-Mougy, Prof. Mona Wasif, Prof. Hala Farawela, Prof. Afaf ElBannah, Prof. Iman Mansour, Prof. Hala Ali, Prof. Hala Gabr, Prof. Sahar Abdel Atty

d. Key research subjects i. HCV ii. Stem Cell Research iii. Neurodegenerative diseases iv. Infection prevention and control v. Molecular basis of Hematological disorders vi. Juvenile Diabetes Mellitus.

2. Research Projects

Ministry of Higher Education funded by the Project Management Unit: Improving the performance of microbiology laboratory

and its preparation for accreditation by ISO15189. Budget is 530 000 LE

(Investigator: Prof. Dr. Amani ElKholy)

STDF Basic & Applied Research Grants in the framework of the German-Egyptian Research Fund (GERF 2010): Strategies

to improve early engraftment of transplanted cardiomyocytes. (Principal

investigator: Prof. Dr. Heba Abdel-Razik, Co-investigators: Prof. Dr. Doha Abdel-

Hamid Mokhtar &A. Prof. Rania Ahmed Zayed).

STDF projects: 1. Rapid molecular diagnosis of congenital Adrenal Hyperplasia by Strip

hybridization assay.

2. The Pathogenesis of Hepatitis C Virus Vertical Transmission

(Projects PI: Prof. Dr. Fatma Ahmed F. El Mougy)

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3. Journal Editorialships /Editorial Reviewers a. Editorialships

i. Editor in Chief Egyptian Journal Of Laboratory Medicine (Prof. Dr. Ali Shams ElDin)

ii. Managing Editor Egyptian Journal Of Laboratory Medicine (Prof. Dr. Naguib Zohair)

iii. Assistant Editors Egyptian Journal Of Laboratory Medicine

o Prof. Sahar Abdel Atty o A. Prof. Mervat Khorshied o A. Prof. Heba Gouda

b. Reviewers i. The Egyptian Journal of Hematology Prof. Dr. Azza Mostafa ii. The Egyptian Journal of Hematology & Research (Prof. Dr. Azza Mostafa) iii. Reviewer of STDF Projects

Prof. Dr. Azza Mostafa

Prof. Dr. Samia Rizk iv. The Cairo University Medical Journal (Prof. Dr. Azza Mostafa) v. Journal of Egyptian Heart Journal (Prof. Dr. Amani El Kholy) vi. Journal of Laboratory Medicine

Prof. Dr. Azza Mostafa

Prof. Dr. Amani El Kholy vii. Journal of Advanced Research

Prof. Amani ElKholy

Prof. Hala Ali

Prof. Iman Mandour viii. Journal of Egyptian National Cancer Institute

Prof. Dr. Amani El Kholy

Prof. Hala Ali ix. Arab Journal of Gastroenterology (Dr. Nelly Abulata) x. IJMMS (Prof. Fayza Hassan) xi. Journal of Inherited Metabolic Disease (Prof. Dr. Fayza Hassan) xii. Journal of Infection in developing countries, South African journal of infectious

diseases (Prof. Dr. Amani El Kholy) xiii. Journal of Leukemia Research (A. Prof. Dr. Mervat Khorshied) xiv. Journal of Targeted Oncology

A. Prof. Dr.Mervat Khorshied

A.Prof. Dr. Heba Gouda xv. Journal of Blood, Coagulation & Fibrinolysis (A. Prof. Dr. Heba Gouda) xvi. Journal of Medicine and Biomedical Sciences (Prof. Dr. Eiman AbdulRahman) xvii. Journal of Medicine and Medical Sciences (A. Prof. Dr. Rania Zayed) xviii. International Journal of Medicine and Medical Sciences (A. Prof. Dr. Rania

Zayed) xix. Nutrition, Metabolism and cardiovascular Diseases Journal (A. Prof. Dr. Rania

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Zayed) xx. Journal of Pregnancy Hypertension (A. Prof. Dr. Asmaa Abd El-Aal) xxi. Journal of Gene Therapy and Molecular Biology

A. Prof. Dr. Manal Makhlouf

A. Prof. Nelly Abulata xxii. Journal of Cancer Research and Clinical Oncology (A. Prof. Dr. Manal

Makhlouf) xxiii. Comparative Clinical Pathology Journal

Prof. Dr. Sahar Abdel Atty

Prof. Dr. Iman Mandour

A. Prof. Dr. Marianne Samir

A. Prof. Dr. Mervat Khorshied

A. Prof. Dr. Heba Gouda

A. Prof. Dr. Rania Zayed

A. Prof. Dr. Asmaa Abd El-Aal

A. Prof. Dr. Manal Makhlouf

A. Prof. Dr. Hanan Madani

Dr. Mona Fathy

Dr. Nahed Mohamed xxiv. Clinical Biochemistry (A. Prof. Dr. Somia Moussa) xxv. Indian Journal of Medical Microbiology (A. Prof. Dr. Maha Gaafar) xxvi. Lab Medicine (A. Prof. Dr. Somia Moussa) xxvii. Journal of Cancer Science & Therapy (A. Prof. Dr. Somia Moussa) xxviii. Molecular Diagnosis & Therapy Journal (A.Prof. Marianne Samir) xxix. European Journal of Drug Metabolism and Pharmacokinetics (A.Prof.

Marianne Samir) xxx. Journal of Clinical Laboratory Analysis (A.Prof. Marianne Samir) xxxi. PLOS One Journals (A.Prof. Marianne Samir) xxxii. Journal of the Egyptian Cancer Institute (Prof. Amani ElKholy) xxxiii. Ibnosina Journal of Medicine and Biomedical Sciences (Prof. Eiman

M.AbdulRahman) xxxiv. The Indian Journal of Medical Microbiology (Prof. Iman Behiry) xxxv. International Journals of microbiology research and reviews (Prof. Mona Mohie

ElDin) xxxvi. European Scientific Journal (A. Prof. Rania Zayed) xxxvii. International Journal of Medicine and Medical Sciences (A. Prof. Rania Zayed) xxxviii. Journal of Pediatric Infectious Diseases (A. Prof. Rania Zayed) xxxix. Journal of DNA and Cell Biology (A. Prof. Rania Zayed)

4. Associations/Societies/ Organizations/ Committee

Memberships a. Membership in Associations/ Societies

i. International Society for Neonatal Screening (Prof. Dr. Fayza Hassan)

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ii. American Association of Clinical Chemistry Prof. Dr. Nadida Gohar Dr. Riham ElSayed

iii. European Society of immunodeficiency (Dr. Safa Sayed Meshal) iv. Egyptian Association of Clinical Chemistry (Prof. Dr. Fayza Hassan) v. Arab Society for Infectious Diseases and Antimicrobial Chemotherapy

(ASIDA) (Prof. Dr. Amani El Kholy) vi. Egyptian Society for Infection Control (Prof. Dr. Amani El Kholy) vii. Society of Practitioners of Infection control in Egypt: Board member Prof.

Dr. Amani El Kholy) viii. Egyptian hematology group (EHOG) (Prof. Dr. Amani El Kholy) ix. Egyptian Patient Safety Association (EPSA) (Prof. Dr. Amani El Kholy)

x. American Society for Microbiology (Prof. Dr. Amani El Kholy) xi. International Federation for Infection Control (Prof. Amani El Kholy, Prof.

Dr. Mona Mohie Eldin) xii. Society of Healthcare Epidemiology of America (Prof. Dr. Amani El Kholy) xiii. Society of Clinical Research Associates (Prof. Dr. Samia Rizk) xiv. European Bone Marrow Phathology working group”, an affiliate of the

European Association for Hematopathology (Prof. Dr. Samia Rizk) xv. American Society of Clinical Pathology (Prof. Dr. Samia Rizk) xvi. European Association of Hematopathology (Prof. Dr. Samia Rizk) xvii. Thalassemia International Federation (Prof. Dr. Samia Rizk) xviii. MAREP- SPIC- Egypt (Prof. Mona Mohie Eldin) xix. The Egyptian Society of Laboratory Medicine

Prof. Mervat El Ansary

Prof. Fayza Hassan

Prof. Dr. Azza Mostafa

Prof. Dr. Taghrid Gaafar

Prof. Dr. Amani El Kholy

Prof. Dr. Nadida Gohar

Prof. Dr. Samia Rizk

Prof. Dr. Sahar Abdel Atty

Prof. Dr. Hoda Abdel Ghany

Prof. Dr. Hala Ali

Prof. Dr. Marianne Morgan

Prof. Dr. Doha Mokhtar

A. Prof. Manal Kamal

A. Prof. Dr. Maha Gaafar

A. Prof. Dr. Mona Mohie Eldin

A. Prof. Dr. Nohair Soliman

A. Prof. Dr. Marianne Samir

A. Prof. Dr. Manal Makhlouf

A. Prof. Hanan Madani

Dr. Nadia Sewelam

Dr. Nelly Abulata

xx. Egyptian Society of Hematology Prof. Dr. Mervat El Ansary

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Prof. Dr. Azza Mostafa

Prof. Dr. Taghrid Gaafar

Prof. Dr. Amani El Kholy

Prof. Dr. Samia Rizk

xxi. Egyptian Society of Hematology & Research Prof. Dr. Azza Mostafa

Prof. Dr. Hoda Abdel Ghany

Prof. Dr. Hala Ali

Dr. Nelly Abulata

xxii. Society of Nephrology (Prof. Dr. Mervat El Ansary)

xxiii. Society of Stem cell (Prof. Dr. Mervat El Ansary)

xxiv. Society of AABB (Prof. Dr. Mervat El Ansary)

xxv. The Egypt Society of Hepatology, GIT & Infectious Disease (Prof. Dr. Mervat El Ansary)

xxvi. Egyptian Inherited metabolic disorder friends association (Dr. Mohamed Abdel Monem)

xxvii. Egyptian group for Orphan renal diseases (EGORD) (Dr. Mohamed Abdel Monem)

xxviii. Society of Haematology and Transfusion Medicine (Prof. Dr. Mervat El Ansary)

xxix. Egyptian Society for progenitor cell research (Prof. Dr. Mervat El Ansary)

xxx. Egyptian Society of Liver Cancer (Prof. Dr. Mervat El Ansary)

xxxi. Metabolic diseases patients friends association (Prof. Dr. Marianne Morgan)

xxxii. Scientific Society of inborn errors of metabolism (Prof. Dr. Sahar Abdel Atty)

xxxiii. Association for Women’s Total and Advanced Development (AWTAD) – (Dr. Nelly Abulata)

xxxiv. American Society for Microbiology (Prof. Dr. Amani El Kholy) xxxv. International Nosocomial Infection Control Consortium (Prof. Dr. Amani

El Kholy) xxxvi. International Society for Cardiovascular Infections (Prof. Dr. Amani El

Kholy) xxxvii. Arab Society of Infectious Diseases and Antimicrobials (Dr. Dina

Hassan) xxxviii. American society of Laboratory Medicine (Dr. Dina Hassan) xxxix. The Doctors French Egyptian Scientific Society (Prof. Iman Behiry)

b. Memberships in Organizations i. Public responsibility in medicine and research (PRIM&R) organization

(Prof. Dr. Samia Rizk)

ii. Technical advisory panel in: The Joint Commission. Preventing Central Line–Associated. Bloodstream Infections: A Global Challenge, a Global Perspective. Oak Brook, IL: Joint Commission Resources, (Prof. Dr.

Amani El Kholy)

24

iii. Kasr ElAini Friends’Association (KEFA) Prof. Dr. Iman Mandour

Prof. Dr. Marianne Morgan

Dr. Nelly Abulata

Dr. Mohamed Abdel Moneim

c. Memberships of Committees i. National hepatitis C control committee at Ministry of health(Prof. Dr.

Iman Behiry) ii. Higher Committee for Infection Prevention and Control, Cairo University

Hospitals (Prof. Dr. Amani El Kholy) iii. Higher Education Promotion Committee for Assistant Professors and

Professors (Prof. Dr. Amani El Kholy) iv. Infection Control Committee for university hospitals, Supreme Council

for Universities, Ministry of Higher Education (Prof. Dr. Amani El Kholy) v. National Task Force Committeee for Infection Prevention and Control

(Prof. Dr. Amani El Kholy) vi. National Task Force Committeee for Prevention of hepatitis and

Injection safety (Prof. Dr. Amani El Kholy) vii. Higher Committee for Infection Prevention and Control in Cairo

University Hospital (Prof. Dr. Amani El Kholy) viii. Cairo University Specialized Paediatric Hospital Committee (

CUSPH) (Prof. Dr. Mona Mohie ElDin)

5. Publications

A disintegrin and metalloproteinase 33 (ADAM33) gene polymorphism association with asthma in Egyptian children. Mona M. El-Falaki, Manal M. Wilson, Ghada M. Ezzat, Doha A. Mokhtar, Mohamed S. El Baz, Dina H. Hamed. Egyptian Journal of Medical Human Genetics, Volume 14, Isue 1, January 2013.

A Novel Mutation of the Ornithine Transcarbamylase Gene Leading to Fatal Hyperammonemia in a Liver Transplant Recipient. Mukhtar, H. Dabbous, R. El Sayed, F. Aboulfetouh, M. Bahaa, A. Abdelaal, M. Fathy, M. El-Meteini: Am J Transplant; 13(4): 1084-7 (2013).

A systematic clinical comparison Elmonem MA, Ramadan DI, Issac MSM, Selim LA, Elkateb SM. Blood spot versus plasma chitotriosidase, Accepted for publication (20th October 2013) at Clinical Biochemistry.

Adrenomedullin concentrations in acute asthmatic children, Mohammed Abdel Motey, Mohamed Baz, Nelly Abulata & Shaima Salah, Journal of Arab Child, January 2013.

Assessment of respiratory involvement in children with mucoplysaccharidosis using pulmonary function tests, El Falaki MM, Girgis MY, Ali AA, Elmonem MA, Ismail HM Accepted for publication (14th October 2013) at Egyptian journal of medical human genetics.

Association of E-Selectin Gene Polymorphism and Serum PAPP-A with Carotid Atherosclerosis in End-Stage Renal Disease. Marianne Samir M. Issac, Alaa Afif, Nadida A. Gohar, Nahla A. Fawzy Fayek , Bahaa Zayed , Heba Sedrak , Lamiaa Adel Salah El Din. Mol Diagn Ther. Epub 23 October 2013.

25

B- Cell Activating Factor Promoter Polymorphisms in Egyptian Patients with Systemic

Lupus Erythematosus. Rania A. Zayed, Hala F. Sheba, Mennat Allah K. Abo

Elazaem, Zainab A. Elsaadany, Lobna O. Elmessery, Jelan A. Mahmoud, Dalia R.

Abdel Rahman and Faten R. Abdou. Annals of Clinical & Laboratory Science, vol. 43,

no. 3, 2013.

Biotyping and Molecular Characterization of Klebsiella pneumoniae Producing

Extended-Spectrum Beta-Lactamase in Cairo, Egypt: A Multicentre Study. Aisha Abu

Aitta1, Manal El Said, Doaa Gamal, Amani El-Kholy, Momtaz Omer, Mohmoud Kamel,

Hesham Mohamed. Researcher 2013; 5 (9).

Blood Spot versus Plasma Chitotriosidase: A Systematic Clinical Comparison. Mohamed A Elmonem, Dalia I Ramadan, Marianne S. M. Issac, Laila A Selim, Sara M Elkateb. Clinical Biochemistry Epub 24 October 2013.

CD4+ CD25+ cells in type1 diabetic patients with other autoimmune manifestations Abd Elaziz D., Hafez M.; Galal N., Meshaal S., Aisha El Marsafy A. (2013). "". JAR; accepted on September 2013.

Chromogenic Cica-β Testing for Detection of Extended-Spectrum and AmpC β-

Lactamases Among Cefoxitin-Resistant Isolates. Mona A. Wassef and Eiman

Mohammed Abdul Rahman. Lab Medicine. Feb 2013, 44, 1:18-21.

Comparative characteristics of endothelial like cells derived from human adipose mesenchymal stem cells and umbilical cord blood-derived endothelial cells. Taghrid M. Gaafar, Hala A. Abdel Rahman, Wael Attia, Hala S. Hamza, Konrad Brockmeier & Rabab E. El Hawary. Clin Exp Med.

Comparison between Different Cord Blood Stem Cell Populations in Efficiency of

Transdifferentiation into Hepatic Lineage. Hala Gabr, Rania Zayed, Ahmed Rezk

Elzayat. ESJ June 2013/special/edition/No.3.

CYP 17 and Estrogen Receptor α Gene Polymorphisms: Association with Breast Cancer Susceptibility and Clinico-pathological Parameters in a cohort of Egyptian Patients. Nadida Gohar, Dina El Gayar, Marianne Samir M. Issac, Mohammed Shehata, Yasmine Khater, Ezzat Safwat. Comp Clin Pathol Epub 14 November 2013.

Cytotoxic T lymphocyte antigen 4 gene polymorphism in Systemic Lupus Erythematosus Egyptian patients; Nancy El Guindy, Heba A. AbdEl Ghaffar, Rasha El Refai, Rabab E. El Hawary, Comparative clinical pathology; Comparative clinical pathology.

Detection of trisomy 4 and 10 in Egyptian pediatric patients with acute lymphoblastic leukemia. Somaia Mousa, Shady Mostafa, Iman Shahin, Esam Elnoshokaty. Clinical Laboratory. 2013.130308.

Dihydrorhodamine Flow cytometric test in Egyptian patients with symptoms suggestive of Chronic Granulomatous Disease. Meshaal S., Elhawary R., Alkady R., Abdel Aziz D., Galal N., Boutros J, El Marsafy A. Eg J Lab Med. Accepted on April 2013.

Do MDR1 and SLCO1B1 Polymorphisms Influence the Therapeutic Response to Atorvastatin? A Study on a Cohort of Egyptian Patients with Hypercholesterolemia. Mona F. Shabana, Amal A. Mishriki, Marianne Samir M. Issac & Sameh W. G. Bakhoum. Mol Diagn Ther. 2013; 17: 299–309.

Enhancing ex vivo Expansion of cord blood-derived Unrestricted Somatic Stem Cells for Clinical Applications. Z.D, emerdash, H. EL Baz, F. Mahmoud, S. Mahmoud,K. Maher,T. Gaafar, S. Shawky, M. Hassan,D. Abdelhady ,and T. Taha. Cell proliferationJournal, 2013;46:628-636

26

Frequency of human hemochromatosis (HFE) gene mutations in Egyptians with b-thalassemia. Doha A. Mokhtar, Mona M. Hamdy and Ahmed M. Badr. Egyptian Journal of Haematology 2013, Vol 38, No 1.

Incidence and pathogen distribution of healthcare-associated infections in pilot hospitals in Egypt. See I, Lessa FC, ElAta OA, Hafez S, Samy K, El-Kholy A, El Anani MG, Ismail G, Kandeel A, Galal R, Ellingson K, Talaat M. Infect Control Hosp Epidemiol. 2013 Dec; 34(12):1281-8. doi: 10.1086/673985. Epub 2013 Oct 30.

Influence of transforming growth factor-b1 gene polymorphism on clearance of

hepatitis c virus and development of hepatic fibrosis among egyption patients with

chronic hcv infection. Ela. Mervat, A.N.Aya, Abdel H. Hanan, Abdel H. Hanan and Abd

Fl f. Walaa. The Arab Journal of Laboratory Medicine May 2013 Vol. 39, No. 2: 427 –

435.

Is There a Role for MDR1, EPHX1 and Protein Z Gene Variants in Modulation of Warfarin Dosage? A Study on a Cohort of the Egyptian Population. Marianne Samir M. Issac, Maggie S. El-Nahid, Marian Youssry Wissa. Mol Diagn Ther. Epub 3 October 2013.

Mannose-binding lectin exon 1 polymorphisms in Egyptian patients with chronic hepatitis C virus infection. Amaal Abdelaal & Nehad Mossad & Hanan Abdel Hafez & Naglaa Elsayed. Comp Clin Pathol Vol 22 No 4 July 2013

Mesenchymal stem cell separation from Wharton’s jelly and its differentiation into

keratinocytes, Irene Ellia M. Bishai, Mervat Saad El Ansary, Noha M. Hosny Shaheen,

Reem Jan Farid. Journal of Comp Clin Pathol (2013).

Mutational spectrum of CTNS gene in Egyptian patients with nephropathic cystinosis, Soliman NA, Elmonem MA, van den Heuvel L, Abdelhamid RH, Gamal M, Bongaers I, Marie S, Levtchenko E. Accepted for publication (5th December 2013) at Journal of Inherited Metabolic Disease reports.

P2Y12 Receptor Gene Polymorphism and Anti-platelet effect of Clopidogrel in patients with Coronary artery disease after Coronary stenting, Naguib Zoheir, Samah Saleh, Nelly Abulata, Doaa Khafagy, Mehry El Sobky & Amr Mostafa. Blood, Coagulation & Fibrinolysis, June 2013 (IF: 1.4)

Plasma Annexin A5, anti-Annexin A5 antibodies and Annexin A5 polymorphism in Egyptian female patients with systemic lupus erythematosus and antiphospholipid syndrome. Aya Nasef, Mona Ibrahim, Nermine Riad, Somaia Mousa. Clinical Laboratory. 2013.130112.

Plasminogen activator inhibitor-1 4G/5G gene polymorphism in hemodialysis patients with cardiovascular disease. Baheia H. Mostafa, Doha A. Mokhtar, Ahmed M. Badr and Nasser M. Gamal el Din. Egyptian Journal of Haematology 2013, Vol 38, No 1.

Report on behalf of the International Nosocomial Infection Control Consortium. Victor D. Rosenthal, MD; Rosana Richtmann, MD; Sanjeev Singh, MD; Anucha Apisarnthanarak, MD; Andrzej Ku¨bler, MD; Nguyen Viet-Hung, MD; Fernando M. Ramı´rez-Wong, MD; Jorge H. Portillo-Gallo, MD; Jessica Toscani, MD;9 Achilleas Gikas, MD;10 Lourdes Duen˜as, MD;11 Amani El-Kholy, MD;12 Sameeh Ghazal, MD;13Dale Fisher, MD;14 Zan Mitrev, MD;15 May Osman Gamar-Elanbya, MD;16,17 Souha S. Kanj, MD;18Yolanda Arreza-Galapia, MD;19 Hakan Leblebicioglu, MD;20 Sonˇa Hlinkova´, MD;21,22 Badaruddin A. Memon, MD;23Humberto Guanche-Garcell, MD;24 Vaidotas Gurskis, MD;25 Carlos A´ lvarez-Moreno, MD;26 Amina

27

Barkat, MD;27Nepomuceno Mejı´a, MD;28 Magda Rojas-Bonilla, MD;29 Goran Ristic, MD;30 Lul Raka, MD;31 Cheong Yuet-Meng, MD32. ICHE 2013, vol. 34, no. 6

Role of CYP2C9, VKORC1 and Calumenin Genotypes in Monitoring Warfarin

Therapy: An Egyptian Study. Naguib Zohir1, Reham Afifi1*, Asmaa Ahmed, Zinab Aly,

Mehry Elsobekey, Heba Kareem, Rehab Helmy. Macedonian Journal of Medical

Sciences. 2013 Dec 15; 6(4): 414-420.

Source, Pattern and Antibiotic Resistance of Blood Stream Infections in Hematopoietic Stem Cell Transplant Recepients. El Mahallawy H, El Kholy A et al. JENCI-D-13-00013R4 In press, 2013.

The presence of blaKPC-mediated resistance in Enterobacteriaceae in Cairo

University hospitals in Egypt and its correlation with in vitro carbapenem susceptibility.

Soheir Fathy Helal; Nevine Gamal Eldin El-Rachidi; Eiman Mohammed

AbdulRahman; Dina Mohammed Ahmed Hassan. Journal of Chemotherapy.

Tissue factor expression on blood monocytes in patients with hepatitis C virus-

induced chronic liver disease. N. E. El-Bassiouni & L. O. El Messery & R. A. Zayed

&O. B. Metwally & M. Y. Zahran & O. M. Mahmoud &R. A. Ibrahim & A. E. El

Bassiouny. Comparative Clinical Pathology, published online May 2013.

Validation of a Proposed Warfarin Dosing Algorithm Based on the Genetic Make-up of Egyptian Patients.mSherif M.M. Ekladious, Marianne Samir M. Issac, Sahar Abd El-Atty Sharaf, Hazem S. Abou-Youssef. Mol Diagn Ther 2013; 17: 381-390.

Vascular Endothelial Growth Factor gene polymorphism in Egyptian women with spontaneous recurrent miscarriage, Nelly Abulata, Abeer Nasr & A.M. Hussein, The Journal of the Egyptian Society of Laboratory Medicine, February 2013.

Viral causes of acute respiratory infection among Egyptian children hospitalized with

severe acute asthma exacerbation. Nadia M. Amin, Noussa R. El Basha, Nihal M. El

Rifai, Mohamed S. El Baz, Iman H. Draz, Amani A. El Kholy and May M. Sherif. . J

Egypt Public Health Assoc 2013, 88:52–56.

6. Training/ Courses/ Workshops Activities a. Training/ Courses/Workshops Organized by Faculty Members

2013-2014 i. Training Program in Regenerative Medicine (TPRM) a partnership with the

University of Toronto in Canada (webcasted course)

Prof. Dr. Mervat ElAnsary (Director)

Dr. Mohamed Fateen (Moderator)

Dr. Riham ElSayed (Moderator) ii. Workshop: Full Microbiology Lab Automation Solutions and its Benefits in

collaboration with BioMerieux International scientific Office, December 2013 (Prof. Dr. Amani El Kholy)

iii. Workshop: How to write better multiple choice questions for the medical sciences, in collaboration with Dr Shaadi El Swaify, College of Osteopathic Medicine. Blacksburg, VA, USA (Prof. Dr. Amani El Kholy)

iv. Training of doctors on Basics of infection control (Training course) at The Egyptian Medical Syndicate.(From 4- 23 May 2013) (Prof. Dr. Iman Behiry)

28

v. Competency based program of (training of trainers on infection free services) and joining the core team of Misr El Kheir as senior trainer. (27 Jan. 2013) (Prof. Dr. Iman Behiry)

b. Training/ Courses/Workshops Participation by the Faculty

i. Real time PCR workshop, (Part of ESLM Activities) 2013 22 – 24 April, 2013 (Prof.

Dr. Sahar Abdel Atty, Prof. Dr. Marianne Samir). ii. Quality Assurance Workshop, 8-10 March 2011 at AlAzhar Conference Centre

(Dr. Dina Mohammed Hasssan) iii. ESBL's and KPC's to test or not to test.17th April 2012 in the 23rd annual

conference of ESLM (Dr. Dina Mohammed Hasssan). iv. Emerging, zoonotic and infectious diseases that was held in the national research

center in collaboration with George Washington University medical center on April 15-18, 2013 (Prof. Dr. Eiman AbdulRahman).

v. Introduction to Biology – The Secret of Life by Eric Lander, MIT University, Online Course (September 2013 – December 2013) (Dr. Riham ElSayed)

vi. Epigenetic Control of Gene Expression, University of Melbourne, passed with distinction, Online course (July 2013 - August 2013) (Dr. Riham ElSayed)

vii. Use of zebrafish as an animal model in congenital kidney diseases: Institute of Genetic Medicine, Newcastle University – UK (June 2013). (Dr. Riham ElSayed)

viii. RAMSES (Stem cell and pediatric cardiology, hand in hand) workshop:

IPS cells(reprogramming, culture & characterization) 9 MAY 2013

Magnetic separation techniques 11 MAY 2013

(Prof. Dr. Shereen Shawky, Dr. Safa Meshaal)

7. Conference Activities a. Conferences Organized by the Faculty

i. The 4th Annual Conference of The Clinical & Chemical Pathology Department,

CLINCHEM 28-29 April 2013 (Is Regenerative Medicine a hope or hype?)

-Prof. Dr. Mervat AlAnsary

-Prof. Dr. Hala Gabr

-Prof. Dr. Sahar Abdel Atty

ii. 24th Annual Conference of The Egyptian Society of Laboratory Medicine: A

clinician-Friendly Approach 13-15 April, 2013, " Passenger Lymphocyte

Syndrome in Solid Organ Transplantation "

-Prof. Dr. Mervat AlAnsary

-Prof. Dr. Soheir Helal

-Prof. Dr. Fatma ElMougy

iii. Co Organized the Annual Conference of the Egyptian Society of Hematology & Research (Prof. Dr. Azza Mostafa)

iv. Co Organized the Annual Conference the Annual Conference for Thalassemia (Prof. Dr. Azza Mostafa)

29

b. Conferences Participation by the Faculty i. Oral Presentations

" Dendritic cells in stem cell therapy ", The 13th Annual Conference of

The Egyptian Society for Study of Updates in Hepatology and

Gastroenterology in Collaboration with The Egyptian Society for study of

NAFLD-NASH and its complications, May 30-June 1st, 2013, (Prof. Dr.

Mervat AlAnsary).

Impact of serology and molecular methods on improving the

microbiologic diagnosis of infective endocarditis in Egypt, presentation at

the 3rd ASMET – The ASM Emerging Technologies Conference, to be

held June 25 – 28, 2013, at the Swissotel Grand Efes, in Izmir, Turkey

(Prof. Dr. Amani El Kholy).

Device associated Infections in Adult Intensive Care Units in Public Vs Private Hospitals in Egypt. Amany El Kholy, Iman Beheiry, Mervat enany, May Abd ElFatah, 2nd International Conference on Prevention & Infection Control (ICPIC 2013), Geneva, Switzerland, 25−28 June 2013 (Prof. Dr. Amani El Kholy).

Prevention of re-use of single-use suction catheter decreased the vap incidence density in a resource-limited adult ICU in Egypt. M. Enany 1, M. Sherif 1, A. A. El Kholy 1, G. L. Saeed 1, E. Sobhy, ICPIC13 (Prof. Dr. Amani El Kholy).

Fungal endocarditis: early diagnosis aiming at better outcome and predictors of mortality, ISCVID 2013 (Prof. Dr. Amani El Kholy).

The impact of routine brain ct angiography on treatment decision and mortality in patients with infective endocarditis, ISCVID 2013 (Prof. Dr. Amani El Kholy).

Neonatal Infections-Related Mortality & Morbidity in Egypt (NIRMM) Conference .The George Washington University and the National Research Centre, Cairo, 2013 (Prof. Dr. Amani El Kholy)

Blood culture Updated endocarditis diagnosis and management seminar, LRC, 20-11 -2012 (Dr. Dina Mohammed Hasssan).

TB a Hidden risk. And; Face infection before and after joining work, The 1st Annual conference of occupational health inside hospitals (23rd of March 3013at Cairo University). (Prof. Dr. Iman Behiry)

HCV infection and prevention, The 28th Annual Congress of Quality and Medicine, from 4-8March 2013 at Tanta University (Prof.Dr. Iman Behiry)

Introduction to clinical pathology, Your Way To Be a Successful Doctor, The 3rd Annual conference of house officers and fresh Graduates 27-28February ,2013 At The Egyptian Medical Syndicate(Prof. Dr. Iman Behiry)

Blood spot versus plasma chitotriosidase: A systematic clinical

comparison Egyptian society of laboratory medicine (ESLM) conference

(Cairo, April 2013) (Dr. Mohamed Abd Elmoneim)

CTNS mutations in Egyptian patients with nephropathic cystinosis.,

Egyptian society for pediatric nephrology and transplantation (ESPNT)

conference in partnership with Global kidney academy (GKA) (Cairo,

May 2013) (Dr. Mohamed Abd Elmoneim)

30

Identification and differentiation of the most clinically involved candida species in neonates with candidemia admitted to NICU in Cairo-University Specialized Paediatric Hospital (CUSPH), Microbiological analysis of bacterial and fungal Late onset sepsis in Neonatal Intensive Care Unit Cairo University, Neonatal Infection-Related Mortality & Morbidities Current Status, future perspectives and role of technology

GWU-NRC Conference - April 15-18, (Prof. Dr. Mona Mohie Eldin)

DVT from the Laboratory point of view, The Silent Killer; Kasr AlAiny protocol for prophylaxis and treatment, (June 2013 LRC, Cairo Egypt) (Dr. Nelly Abulata)

“Impact of Circulating Erythrocyte- derived microparticles on Coagulation

activation in sickle cell disease”, International Conference on Hematology

and Blood Diseases. Raleigh, USA (September 23-25, 2013) (A.Prof.

Rania Zayed)

“Impact of Circulating Erythrocyte- derived microparticles on Coagulation

activation in sickle cell disease” 14th International Thalassemia

Conference. Cairo, Egypt (8-9/5/ 2013) (A.Prof. Rania Zayed)

“Comparison between Different Cord Blood Stem Cell Populations in

Efficiency of Transdifferentiation into Hepatic Lineage” 1st Annual

International Interdisciplinary Conference. Azores, Portugal (24-26/4/

2013) (A.Prof. Rania Zayed)

Immun modulatory role of mesenchymal stem cells derived from wharton

jelly and adipose tissue, RAMSES Final Conference in collaboration with

the Egyptian Working Group of Pediatric Cardiology (Stem cells and

pediatric cardiology Hand in Hand) 7-9 May 2013 (Prof.Dr. Shereen

Shawky)

Mesenchymal stem cells from pediatric patients with aplastic anemia:

isolation, characterization, adipogenic, and osteogenic differentiation, 4th

Annual Scientific Conference of the Clinical and Chemical Pathology

Department, CLINCHEM 2013 “Is Regenerative Medicine a hope or a

hype?” 28-29th of April 2013 (Prof. Dr. Shereen Shawky)

ii. Poster Presentions

CYP 17 and Estrogen Receptor α Gene Polymorphisms: Association with Clinico-pathological Parameters in Egyptian Breast Cancer Patients 5th Breast-Gynecological International Cancer Conference (BGICC), 17-18 January 2013, Fairmont Towers Hotel, Cairo, Egypt (Nadida Gohar, Dina El Gayar, Mohammed Shehata, Marianne S.M. Issac, Yasmine Khater, Ezzat Safwat).

The presence of blaKPC-mediated resistance in Enterobacteriaceae in Cairo University hospitals in Egypt and its correlation with in vitro carbapenem susceptibility. Emerging technology conference in the 3rd ASM, June 25- 28 -2013, Turkey (Dr. Dina Mohammed Hasssan)

Prevalence of Clostridium difficile among cases of antibiotic associated diarrhea in hospitalized patients in an Egyptian hospital. IMED- February – 2013 (Prof. Dr. Mona Mohie Eldin)

31

Chitotriosidase enzyme can be used as a screening marker and a

therapeutic, monitor for Nephropathic Cystinosis at International pediatric

nephrology association (IPNA) conference (Shanghai, China, August

2013). (Dr. Mohamed Abd Elmonem)

Screening of high risk Egyptian children with suspected inborn errors of

metabolism using tandem mass spectrometry: a 5 year report,

International congress of inborn errors of metabolism (ICIEM)

(Barcelona, Spain, September 2013) (Dr. Mohamed Abd Elmonem)

The prevalence of inborn errors of metabolism among Egyptian pediatric

patients admitted to the intensive care unit using tandem mass

spectrometry, International congress of inborn errors of metabolism

(ICIEM) (Barcelona, Spain, September 2013) entitled (Dr. Mohamed Abd

Elmonem)

Induction of chitotriosidase in human macrophages by incubation with

cystine crystals: Clinical utility in nephropathic cystinosis at American

society of nephrology (ASN) conference (Atlanta, USA, November 2013)

(Dr. Mohamed Abd Elmonem)

Restoration of cardiac function in a rat model of isoproterenol induced

myocardial injury by transplantation of human mesenchymal stem cells,

(ID 341) World Conference on Regenerative Medicine | October 23-

25, 2013 | Leipzig, Germany (Dr. Rabab ElHawary)

Dihydrorhodamine flow cytometric test in Egyptian patients with

symptoms suggestive of chronic granulomatous disease first

international primary immunodeficiencies congress , estoril, Portugal, 7-8

Novenmber 2013 (Dr. Rabab ElHawary)

Detection of CTX-M-type of Extended-Spectrum beta -Lactamases in

Klebsiella spp. in Cairo University Hospitals, 3rd Biennial Pathology and

Laboratory Medicine Update, 27-28/9/2013, UAE. (Dr. Reham Hamed)

c. Conferences attendance by the Faculty i. The 4th Annual Conference of The Clinical & Chemical Pathology

Department, CLINCHEM 28-29 April 2013(Is Regenerative Medicine a

hope or hype?)

ii. The 10th Conference of Egyptian Society of Hematology & Research, 27-

28 November, 2013, " Webcasting from EHA 2013 (Prof. Dr. Mervat

AlAnsary)

iii. 5th annual meeting of infection prevention and control in Cairo University

Hospitals June 2013 (Prof. Dr. Amani ElKholy, Dr. Dina Mohammed

Hasssan)

iv. The 5th Annual Conference of National Hepatology & Tropical Medicine

Research Institute ( NHTMRI ), 20-21 November, 2013 (Prof. Dr. Mervat

AlAnsary)

v. Ramses Final Conference in collaboration with the Egyptian Working

Group of Pediatric Cardiology, 4th International Conference Pediatric

32

Cardiology Department, Cairo University, May 7-9, 2013 (Prof. Dr.

Mervat AlAnsary)

vi. 14th International Conference for Thalassemia May 8-9, 2013. (Prof. Dr.

Mervat AlAnsary)

vii. The 24th Annual Conference of the Egyptian Society of Laboratory

Medicine, 18-20 April 2013

Prof. Dr. Mervat El Ansary

Prof. Dr. Azza Mostafa

Prof. Dr. Taghrid Gaafar

Prof. Dr. Sahar Abdel Atty

Prof. Dr. Shereen Mahmoud

Prof. Dr. Iman Behiry

A. Prof. Dr. Maha Gaafar

A. Prof. Dr. Marianne Samir

A. Prof. Dr. Mervat Khorshied

A. Prof. Dr. Heba Gouda

A. Prof. Dr. Rania Zayed

A. Prof. Dr. Asmaa Abd El-Aal

A. Prof. Dr. Manal Makhlouf

Dr. Reham Hamed

viii. European Health Management Association Annual Conference “What healthcare can afford? Better, quicker, lower cost healthcare services” (June 2013, Milano, Italy) (Dr. Nelly Abulata)

ix. Cord blood Inspection and Accreditation Workshop. Monaco, France, (October 23, 2013) (A.Prof. Rania Zayed)

x. First International Primary Immunodeficiencies Congress; Estoril, Portugal, 7th to 8th November 2013 - RAMSES (Dr. Rabab ElHawary)

xi. Final Conference in collaboration with the Egyptian Working Group of Pediatric Cardiology (Stem cells and pediatric cardiology Hand in Hand) 7-9 may 2013 (Dr. Rabab ElHawary)

xii. Ramses closing Conference “Stem Cells and Pediatric Cardiology Hand in Hand“(May 2013, Cairo Egypt) (A.Prof. Rania Zayed , Dr. Rabab ElHawary, Dr. Nelly Abulata, Dr. Riham ElSayed)

xiii. Emerging disease and surveillance (IMED); 13-15 february – 2013, Vienna-Austria (Prof. Dr. Mona Mohie Eldin)

xiv. First International Primary Immunodeficiencies Congress; Estoril, Portugal, 7th to 8th November 2013 (Dr. Safa Meshaal)

33

VI. LABORATORY SERVICE

34

1. Background Information: Our Laboratories provide an extensive menu of routine & specialized laboratory tests to the patients who seek care at Kasr Al-Ainy Hospitals.

Lab Divisions · Hematology Laboratory

· Clinical Immunology & Molecular Diagnostics

· Clinical Microbiology

· Clinical Chemistry

. Blood Bank

2. Total Annual Productivity 5,521,930

0

1000000

2000000

3000000

4000000

5000000

6000000

35

3. Blood Bank Services

a. Blood Bank Profile: The Blood Bank employees approximately 96 people who

are involved in Blood Donation, Blood Processing and Hemapheresis.

b. Blood Bank Structure: i. The Head of the Blood Bank: Prof. Dr. Mervat Al-Ansary ii. Administrative Director: Dr. Sahar Azab. iii. The Team includes: 8 Specialists, 1 Financial officers, 26 Technologists &

Technicians, 34 Nurses, 17 Administrative Secretaries, 11 Cleaners

c. Blood issued during 2012

Type of Patient No. Of Units

Inpatient Departments

OR & ER

56,628

Sold Units 2,170

Total no of Units issued 58,798

4. New Tests introduced Detection of sepsis bacterial and fungal pathogens by PCR

Detection of 16 respiratory viral pathogens by multiplex PCR

Detection of TB and resistance genes by PCR

Cystine assay in leucocytes for diagnosis of Nephropathic Cystinosis by Tandem

Mass Spectrometry.

Acid sphingomyelinase enzyme assay for diagnosis of Neiman-Pick disease type A/B

by spectrofluorometry

37%

10% 13%

11%

3%

3%

18%

2% 3%

% out of the Total annual productivity of 2013

Manial Lab

Japanese Lab

AbouElRish Lab

Internal Medicine Lab

4th Floor Lab

King Fahd Lab

French Lab

Caesium Lab

Maternity Lab

36

Biotinidase enzyme assay for diagnosis of Biotinidase deficiency by

spectrophotometry.

Galactcerebrosidase enzyme assay for diagnosis of Krabbe disease by

spectrofluorometry.

T cell function assessment, detection of proliferation by flow cytometry in abouelrish

children hospital.

Introducing the extended panel of immune deficiency (Memory and naive cells

assessment by flow cytometry) in abouelrish children hospital.

5. New Techniques introduced Use of Molecular Biology in diagnosis of viral, bacterial and fungal pathogens

6. New Laboratory at the New ER Hospital

Opened September 2013.

Objective: to provide the necessary laboratory service for emergency units in Manial

University Hospital, New Emergency Hospital and Women's Hospital. It aims to

provide the needed service at the right pace for emergencies.

Technical and administrative supervision: Department of Clinical and Chemical

Pathology

Location: New Emergency Hospital - Ground Floor

Characteristics of the place: it has an excellent location as it is part of the New

Emergency Hospital and it mediates other hospitals for which it provides the service.

Its entrance is through the corridor of the ground floor of the Manial university

hospital.

Working Hours: 24 hours divided into two shifts:

• Morning shift: from 8:00 am to 2:00 pm

• Night shift: from 2:00 pm to 8:00 am

Laboratory tests available through emergency lab include:

RBCs Count

TLC

Platelet Count

Differential leukocytic count

Prothrombin time

Activated Partial thromboplastin time.

Fibrinogen

FDPs

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D-Dimer

Pregnancy test

Rh blood grouping

HBsAg, HCV, HIV by rapid test.

Blood culture

Biological fluid, tissue specimen, surgical specimens or bronchoalveolar lavage

culture

Urine analysis and examination: strip assay- direct microscopic examination of

fresh specimens (centrifugal deposit) - culture from uncentrifuged specimen.

Bilirubin

Albumin

ALT

AST

Urea

Creatinine

Uric acid

Blood sugar

Troponin

CK-Total

CK-MB

CK-MB mass

LDH

Calcium

Electrolytes: Na, K, Mg, Cl

Amylase

Blood gases

β-subunit.

E2.

Blood Gases.

7.

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7. Japanese Laboratory Innovations: Why did we seek the innovations (Problems);

Shortage in storage areas.

Frequent error messages received from instruments.

Improper temperature control.

Non convenient laboratory circulation between outpatient clinics and main laboratory.

Limited small secretarial area inconvenient for IT introduction.

Constructions;

Compartmentalization of units leading to more effective temperature control through

split air conditioning unit.

Dividing the outpatient sampling unit and creating a new storage area.

Creating a separate secretarial area with introduction of the IT system.

Relocation of the autoclaving and media preparation unit of the microbiology section

in a separate area instead of inside the main lab.

Construction of a hematopatology unit.

New instruments;

Hematology;

Celldyn emerald (gift)

Centrifuge (donation)

Chemistry;

Beckman coulter AU480 chemistry analyzer ( reagent deal)

Gem premier 3000 blood gases analyzer

Immunology;

Architect ( reagent deal)

2 new air conditioners

New tests introduced;

Hematology

EMA test for spherocytosis

Widening of IHC panel: CD117, CD 10, CD 68, CD 138, anti kappa, anti lambda

Automation of bone marrow biopsy processing, embedding and microtomy which led

to decreased turnover time

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Immunology

Flowcytometry panel of immunodeficiency; CD3,CD4,CD8,CD19,CD56,HLADR,

CD18

Extended pannel: memory and naïve cells: CD45RO,CD45RA,IgD,CD27.

Dihydrorhodamine(DHR) assay for neutrophil functions

T cell function (Proliferation assay by CFSE)

Antidiphteria ab, antitetanus antibodies

PCR

Diagnosis of T.B resistant strain by PCR

Detection of genetic mutations causing cystic fibrosis

Detection of genetic mutations causing FMF.

Microbiology

API test

Helicobacter pylori antigen in stool

E test for antifungal agents

8. Others introducations

Starting application of antibiotic policy in cardiothoracic ICU in collaboration with

Prof. Dr. Zeinab Salah, Professor of Paediatric and head of Cardiothoracic ICU.-

CUSPH- according to guidelines of antibiotic committee- Faculty of medicine – Cairo

University

Introduction of VIVA cards in undergraduate exam

Preparation of the undergraduate book for 6th

year students

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VII. COMMUNITY SERVICES

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Department members have long been involved in a variety of community service activities. While many of these are carried out in areas that are not directly related to the mission of the Department, others are regarded as a part of our overall mission. The activities noted below showcase a few of those activities carried out by our Faculty:

1. Awareness & Training sessions in Infection Control all across Kasr Al-Ainy Hospitals. 2. Awareness & Training sessions in Hospital Safety Measures. 3. Annual Laboratory check-ups for employees who are prone to Hospital acquired

infection. 4. Laboratory Testing as a part of the almost monthly Medical Convoys by Kasr Al-Ainy

Community Service Team to Rural areas. 5. House Officers Career Fair