2013_inhaledparticles

8/12/2019 2013_InhaledParticles

1/22

Kiao Inthavonga, Terry Elms b, Nichola Porter b, Jiyuan Tua

a School of Aerospace, Mechanical and Manufactur ing Engineering

bSchool Applied Sciences

RMIT University, Melbourne, Australia

An integrated and multi-disciplinary

approach to inhalation exposure


2/22

RMIT University Inhaled Particles XI 23-25 September 2013 2

BackgroundCase Study: Dust monitoring at Berwick District Woodworkers Club

Finish Cut (redgum)

Hard cut (camphor laurel)

Hand sanding (redgum) Sanding (Tasmanian Oak)


3/22


An integrated framework

Experimental Measurements

high speed photography

measurement of airflow/ventilation

particle concentration sampling

Computational Fluid Dynamics

fluid flow modelling

fluid-particle interaction modelling

particle diffusion, and reaction with mucus

Lagrangian Particle Tracking

F = ma


4/22



Local Dosimetry = Concentration X Aspiration Efficiency X Deposi tion Fraction


5/22


Sampling

SKC Gravimetric

Personal SamplerDustrak II 8530

unitdust feeder system

dust chamber

Dusttrak vs SKC dust samplingcomparison


6/22

RMIT University SAMME 6

Dust exposure monitoring

0sd

High speed video imaging and long term video capture used.

Real time and gravimetric sampling was performed.

Workshop activity, room geometry are significant factors for inhalation.

How can we mitigate respirable dust?


7/22RMIT University Inhaled Particles XI 23-25 September 2013 7

New extraction ventilation designs

Piccolo ventilation prototype design

Airflow velocity streamlinesCFD model



Influence of ambient airflow

Inthavong K, et al. (2012) Detailed predictions of particle aspiration, affected by respiratory inhalation and airflow. ATMOSPHERIC ENVIRONMENT 62:107-117

External flow velocity vectors

Internal flow velocity streamlines



Wake flow and dust redistribution

wake flow velocity vectors

streamlined body bluff body

vortex shedding behind cylinders



Airborne particle trajectories

Inthavong, Ketal. (2013) Source and trajectories of inhaled particles from a surrounding environment and its deposition in the respiratory airway. INHALATIONTOXICOLOGY 25(5):280-91

Particle trajectories from different upstream source locations



Deposition fractions of inhaled particles

Inthavong, Ketal. (2013) Source and trajectories of inhaled particles from a surrounding environment and its deposition in the respiratory airway. INHALATIONTOXICOLOGY 25(5):280-91

Deposition fractionsAspiration efficiency



Particle-mucus modelling

Air flow

path

Particles



3D to 2D surface mapping

XYZ-Domain UV-Domain


16/22RMIT University2008 Science, Engineering & Health 16

Normalize

Unwrap

Cut surface along

black curves

Inlet

Left Cavity

Outlet

Right Cavity

Divide nasal cavity

Septal

Lateral

Lateral

UV-Mapping of the nasal cavity



3D to 2D surface mapping

www.cfdresearch.com/matlab-2/uv-unwrapping-tool/ .Inthavong et al. (2013), Surface mapping for visualization of wall stresses during inhalation

in a human nasal cavity, RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Animation of the unwrapping techniqueData management tool for unwrapping

Matlab executable

Matlab source files
http://www.cfdresearch.com/matlab-2/uv-unwrapping-tool/http://www.cfdresearch.com/matlab-2/uv-unwrapping-tool/


18/22RMIT University SAMME 18

Wall shear stress mapping

P i l d i i i


19/22


Particle deposit ion mapping

Time dependent deposition pattern for 10m particles in the UV-domain. Each image represents the total fraction

of all deposited particles. 20% deposition efficiency at 10L/min inhalation rate

C t k


20/22


Current work

mucociliary action:

mucus velocity ~50 micron/sec


F t k


21/22


Future work

A k l d t


22/22

RMIT Uni ersit I h l d P ti l XI 23 25 S t b 2013 22

Acknowledgements

Id like to thank my colleagues and supervisors who have contributed to the outcomes

in this presentation Prof Jiyuan Tu (RMIT University)

Yidan Shang (RMIT University)

Mr Bill Munt (Berwick District Woodworkers Club)

Mr Daniel Sullivan (D&E Air Conditioning)

Dr Rui Chen (National Centre for Nanoscience and Technology)

2012: Australian Research Council (project ID DP120103958)

2010: Emerging Research Grant RMIT University

2009: Australian Research Council (project ID LP0989452)

2013_inhaledparticles

Documents