2014 Hopkins C.A.R.E.S Summer Program Symposium:

Celebrating 20 Years of the

Summer Internship Program

July 30, 2014

Armstrong Medical Education Building

1:00-4:30 p.m.

Career Academic and Research Experiences for Students

Schedule

1:00- 1:50p.m. Welcome

Keynote Speakers: Roger H. Reeves, PhD

Rajini Rao, PhD

Recognition of 20 years of the Summer Internship Program

AMEB, 1st Floor Auditorium

2:00- 2:55p.m. Poster Session 1

AMEB, 2nd Floor Lobby SSSP, MERIT, Odd Numbers

2:00- 3:55p.m. Oral Presentations AMEB, 1st Floor Auditoriums

3:00-3:55p.m. Poster Session 2

AMEB, 2nd Floor P-STAR, SURE, Even Numbers

4:00- 4:30p.m. Closing: Roy Ziegelstein, M.D., Vice Dean for Education

Outstanding Students Awards

AMEB, 1st Floor Auditorium

Presentation of Certificates AMEB, 1st Floor Lobby

Keynote Speakers

Roger H. Reeves, PhD

Dr. Roger Reeves is a professor of physiology at the Johns Hopkins University School of

Medicine. Dr. Reeves is also on faculty at the McKusick-Nathans Institute for Genetic Medicine.

Dr. Reeves received his B.S. from Bowling Green State University in 1975 and his Ph.D. from

the University of Maryland in 1983. His postdoctoral work took place at Johns Hopkins

University and he joined the faculty in 1983.

He has studied various aspects of Down syndrome for the last 25 years. He is currently

the co-Director of the Down Syndrome Cognition Project, whose goal is to develop precise,

sensitive and quantitative tests for cognitive problems in DS, and to correlate the overall impact

with genetic factors that may contribute to a better or worse outcome. Dr. Reeves and his lab

recently demonstrated a possible drug to normalize cerebellar hypoplasia which has unexpected

positive consequences on learning and memory in a mouse model of DS.

Among other honors, Dr. Reeves was awarded the Sisley-Lejeune Award for

Translational Research in Intellectual Disabilities in 2012.

Rajini Rao, PhD

Rajini Rao is Professor of Physiology at the Institute for Basic Biomedical Research of

the Johns Hopkins University School of Medicine. She received her PhD in Biochemistry in

1988 from the University of Rochester. Following postdoctoral training in Genetics at Yale

University, she was recruited to Johns Hopkins in 1993, rising through the ranks to become

Professor in 2004. Her research specialty is to understand how transport of ions across cell

membranes relates to human health and disease. Her laboratory was the first to discover the

endosomal Na+/H+ exchangers (eNHE) and recognize them as distinct from those at the

plasma membrane. These transporters have now been implicated in a range of neurological

disorders including autism, attention deficit hyperactivity disorder, epilepsy, mental disability

and Christianson’s syndrome. Currently, Dr. Rao combines the use of yeast and neurobiological

models to determine how mutations in eNHE lead to neurological disease. Dr. Rao's academic activities are divided between education, mentoring and research. As

the Director of the Graduate Program in Cellular & Molecular Medicine, she oversees a multi-

departmental training program with a focus on translational research that includes

approximately 130 faculty mentors and 150 graduate students (Ph.D., M.D. /Ph.D. and

D.V.M/Ph.D.). She is also a faculty mentor in other graduate programs at the School of

Medicine (Biochemistry, Cell & Molecular Biology, and Cellular & Molecular Physiology)

where she teaches graduate and medical students. Dr. Rao plays an active role in advocating for

women and minority groups in academia. She chairs the Committee on Professional

Opportunities for Women at the Biophysical Society, where she has assumed multiple

leadership roles.

2014 Hopkins C.A.R.E.S. Summer Programs

Biophysics Research for Baltimore Teens (BRBT): Biophysics for Baltimore Teens (BRBT) gives Baltimore City public school teens an opportunity to learn laboratory skills for basic biomedical research through a paid 8-week internship. The interns’ exposure to laboratory research will begin with classroom instruction and instructor-supervised laboratory sessions. Promising, interested students will be invited back for a second summer internship of research in an active biophysics research lab. BRBT is offered through the Johns Hopkins Program in Molecular Biophysics (PMB) and PMB graduate students on both campuses will mentor BRBT interns. Center Scholars Program (CSP): The Center Scholars Program, developed by CTY and Dr. Andrew Feinberg’s Center for Excellence in Genome Science (CEGS), is designed to encourage CTY qualified, historically underrepresented minority students to explore careers in scientific research, particularly the field of genomics. Diversity and Academic Advancement Summer Institute (DAASI): The Diversity and Academic Advancement Institute (DAASI) is a partnership between Johns Hopkins School of Medicine Office for Student Diversity and Thread (formerly the Incentive Mentoring Program, IMP). The goals are to three fold: (1) Academic Assistance: Provide a comprehensive, engaging curriculum to bolster participants’ academic self-confidence and

capabilities; (2) Service, Life Skills, and Team Work: Create opportunities for participants to learn important life and professional skills through work opportunities and service learning

experiences; and (3) Visualizing Success: Expose them to science and health educational pathways so that they may visualize the possibility of pursuing careers in science. Institute for NanoBiotechnology Research Experience for Undergraduates (INBT): The Institute for NanoBiotechnology at Johns Hopkins University offers undergraduate students from colleges and universities around the country a chance to participate in research projects in the exciting and rapidly growing area of NanoBiotechnology, a place where biology, medicine, and nanotech meet. Our goal is to promote the interest and completion of a PhD. We provide students with a graduate-level research experience for 10 weeks, where the student is exposed to cutting edge research lab, professional development seminars, and various academic experiences. The Johns Hopkins Internship in Brain Science Program (JHIBS): Project Pipeline Baltimore: The long-term goal of the JHIBS program is to significantly increase the pool of qualified under-represented professional candidates from Baltimore in the neurosciences and mental health medicine through an eight-week summer research and enrichment experience that targets high school juniors and seniors. The program will provide the necessary exposure, knowledge, and career-long mentoring, to help propel students toward a trajectory as a STEM professional. The program has been in existence for seven years funded by the Cohen Foundation and jointly this year with a grant from the National Institutes of Mental Health

Medical Education Initiative for Teens (MERIT): MERIT aims to inspire students from Baltimore City to pursue careers in health care by

preparing them for the multiple challenges that lie ahead. MERIT Scholars learn the

importance of leadership, cooperation, and reflection while cultivating a deep understanding of

their individual roles in solving America’s health disparities through a holistic approach

including weekly Saturday sessions, mentoring, and summer internships. MERIT Scholars

leave the program with an intense passion for eliminating health inequalities, a clear vision of

how to become a health care professional, a toolkit of knowledge and skills necessary for

achieving graduate degrees, and a close-knit community of peers and mentors who will

continue to work collaboratively toward their collective goal of becoming agents of positive

change in their communities.

Psychiatry Summer Training and Research Program (P-STAR): The Psychiatry Summer Training and Research (P-STAR) program offers undergraduates interested in Behavioral and Biological Sciences the opportunity to work for ten weeks under the guidance of a faculty member at Johns Hopkins Medicine. Through one on one work with a faculty mentor, students gain hands on experience in academic research and clinical environments. Students will have participate in many activities such as conducting research alongside leading principal investigators, shadowing physicians at the Johns Hopkins Hospital Psychiatry Outpatient clinic and attending clinical teaching rounds on units. Students also will participate in research seminars, weekly-journal clubs, and personal lunchtime discussions with doctors involved in cutting-edge research. We will have students work in both a laboratory and clinical setting to provide in-depth exposure to Translational Psychiatry, especially that on schizophrenia and related disorders. Pulmonary and Critical Care Medicine Summer Internship Program (PCCM): The Division of Pulmonary and Critical Care Medicine hosts undergraduate students each summer as part of an NIH funded program to enhance diversity in biomedical sciences. Students from around the United States and Puerto Rico join faculty for a ten week, research focused experience that extends from Memorial Day weekend through the first week of August. Students are matched with mentors based on their interests. Students work on specific research projects under the supervision of their mentor. Projects span a broad range of research, from the basic science of endothelial or epithelial cell biology to asthma epidemiology. In addition to the research experience, students participate in a weekly journal club, during which they present primary research articles to their peers and members of the faculty. Students also attend a seminar series featuring faculty members from Johns Hopkins and the NIH. This forum provides students with the opportunity to interact with faculty members and hear different perspectives on issues related to career development. Students interested in clinical medicine are given the opportunity to “round” with the Johns Hopkins Medicine residents, providing a glimpse of life in clinical medicine as a resident at an academic institution.

Stanley Summer Scholars Program (SSSP): The goal of the Stanley Summer Scholars Program of the Stanley Division of Developmental Neurovirology, Department of Pediatrics, is to foster enthusiasm for the study of the etiology, pathology, immunology, prevention and treatment of serious psychiatric diseases such as schizophrenia and bipolar disorder. By offering students the opportunity to gain laboratory experience while working closely with a mentor from the Stanley Division, we hope to encourage the pursuit of careers in basic, translational or clinical research focusing on major mental illnesses. Research performed in the Stanley Division is interdisciplinary and projects are available in a number of fields including molecular biology, immunology, virology, parasitology, cell culture, animal behavior and neuroscience. Program activities include weekly lectures by faculty & postdoctoral fellows describing different aspects of mental illness research, weekly lab meetings, attendance of Schizophrenia and Mood Disorders Rounds in the Department of Psychiatry and a poster/oral presentation by students at the end of the summer. Summer Internship Program Basic Science Institute (SIP/BSI): The Summer Internship Program (SIP) provides intensive experience in research laboratories to college students of diverse backgrounds, including underrepresented minority students, students from economically disadvantaged or underserved backgrounds, and students with disabilities. The purpose of this exposure to biomedical and/or public health research is to encourage students to consider PhD research careers in science, medicine and public health.

Summer Urological Research Experience (SURE): The Summer Urological Research Experience (SURE), is an undergraduate research internship that provide students an opportunity to move beyond the classroom learning experience to gather the knowledge and skills needed to pursue a career founded in the biomedical sciences. SURE is designed to provide a one of a kind research experience to students in the hope to foster an interest in students in the areas of urological and cancer research. Hosted by the James Buchanan Brady Urological Institute, SURE provides a unique opportunity for young scientists to work alongside some of the leading researchers in urology and oncology while utilizing a broad range of techniques and methodologies. Utilizing the Department’s translational research program, young researchers are able to see how research done at the bench can be translated into patient care. In addition to the vast amount of research experience that is gained during the program, students also attend numerous lectures and seminars given by the University's and the Department's numerous gifted faculty that will prepare them for the paradigms, problems, and technologies in biomedical research.

Oral Presentations

Auditorium East

Session 1

2:00-2:10 MERIT Beverly Danh Asthma

2:10-2:20 MERIT Kahlid Fowlkes HIV/AIDS

2:20-2:30 BRBT Joshua Garza BRBT Science Boot camp

2:30-2:40 MERIT Christiona Harris Teen Pregnancy

2:40-2:50 Basic Science Alexandriya Emonds Motor Adaptation in Split-Belt Treadmill Walking

Session 2

3:00-3:10 MERIT Karen Hernandez Alcohol/Drug Abuse

3:10-3:20 MERIT Lidia Hernandez Suicide

3:20-3:30 INBT Elliot MacKrell Immunomodulation via nanoparticle-mediated hyperthermia and ionizing

radiation to enhance resistance against distal tumors

3:30-3:40 PCCM Stephan Maman Mechanisms Involved in Hypoxia-inducible Factor 1 Dependent Upregulation of Aquaporin 1

3:40-3:50 Basic Science Maxine Garcia Alterations in Striatal Volume in the Deer Mouse Model of Primary

Stereotypy

Auditorium West

Session 1

2:00-2:10 INBT Florencia Velez-Cortes

Programmed actuation of photopatterned hydrogel by DNA-crosslink

2:10-2:20 MERIT Savannah Tripp Heart Disease

2:20-2:30 MERIT Precious Tatum Lupus

2:30-2:40 Basic Science Emily Robitschek Mustering troops for the body's war on cancer: polymeric protein complexes to activate the adaptive immune response

2:40-2:50 MERIT Jamia Marriott Depression

Session 2

3:00-3:10 MERIT Taylar Reed Schizophrenia

3:15-3:25 BRBT Candice Jennings BRBT

3:30-3:40 MERIT Joshua Neal Eating Disorders

3:45-3:55 Basic Science Brandi Temple Preclinical studies using bioactive compounds to develop

novel chemoprevention strategies for breast cancer

Poster Presentations

Session 1 (2:00-2:50)

# Name Program Title

1 Esteban Urias BRBT BRBT Science Boot camp

3 Aviva Braier CSP DNA Methylation in Response to Estrogen Treatment in Postpartum Depression Biomarkers

5 Sophia Caldera CSP Methylation and Genetic Variation of the IL-6 Receptor Associated with Age-Related Inflammation

7 Adriana Gonzalez CSP Bioinformatic Analysis and Computational Modeling of miRNA Regulatory Behavior

9 Chris Hadinono CSP Building a High Throughput Bioreactor to Culture Induced Pluripotent Stem Cells into Cerebral

Organoids

11 Brandon Lau CSP

13 Gabriela Memba CSP The Effects of Leptin on Locomotor Activity, Feeding Behavior, Motivation, in OB/OB Mice

15 Savannah Burrell DAASI Organ Donations

17 Shaniya Dwight DAASI Colorectal Cancer

19 Diamond Eveline DAASI Tissue Engineering

21 Tamiaya Ford DAASI Orthopedic Surgery

23 Donte Godwin DAASI Security at Johns Hopkins

25 Tyriq Lee DAASI Cell Tissue Engineering

27 Desirae McKoy DAASI David Rubenstein Children's Health Center

29 Devin Mobley DAASI Heart Cells

31 Sierra Atwater INBT The Synergistic Effects of Interleukin-6 (IL-6) and Interleukin-8 (IL-8) on Cancer Cell Motility

33 Christopher Glover INBT Digital Loop-mediated Isothermal Amplification

35 Nisha Gupta INBT Seeking the mechanism of Eph-A2 dimerization in mammalian cells

37 Abraham Isak INBT Biophysical Characterization of Aging Vascular Smooth Muscle Cells

39 Claire Korpela INBT Tumor Penetrating Supramolecular Hydrogels For Brain Tumor Treatment

41 Sarah Agarrat JHIBS Minimally invasive surgery plus recombinant tissue-type plasminogen activator for intracerebral

hemorrhage evacuation and perihematomal edema

43 Quartay Bradshaw JHIBS Improving access to behavioral treatments for Tourette’s disorder-

45 Trevana Eades JHIBS The Role of Inflammation in Neurosarcoidosis and Rasmussen’s Syndrome

47 Almi Habib JHIBS Quantification of denervation in SOD1 mice at 4 months of age

49 Elmi Habib JHIBS Kv1.3 KO CD4+ CD25hi secrete increased IL-10 and protect from EAE

51 Shahirah Khan JHIBS Quantification of Sweating Test as An Assay for Peripheral Neuropathy in Diabetic Mice

53 Maxwell Lawson JHIBS Comparison of Two Different Neurocognitive Tests for Alzheimer’s Disease and Frontotemporal

Dementia

55 Mon Yi Lwin JHIBS Making a fly: DAT-NewD-GAL4 Transgenic Driver

57 Saida Muktar JHIBS Development of PCS2+:Dendra2 vectors for transgenic expression in Xenopus laevis

59 Tyesha White JHIBS Ex vivo analysis of osteopontin and NeuN in HIV-Associated Neurocognitive Disorder (HAND)

60 Nicola Knights MERIT Physiological Effects of Synthetic Cannabinoids

61 Amanda Lila MERIT Effects of Methamphetamine Self-Administration on Neurotensin and its Receptors in the Rat

Hippocampus

69 Olubukola Abiona PCCM Postjunctional Muscarinic M2 Receptors Regulate Airway Smooth Muscle Contraction

71 Justice Achonu PCCM Evaluation of serum levels of IL33 in asthmatic patients

73 Lauren Askew PCCM Proximity-Dependent Biotin Identification (BioID) of Differential Lamin A and Progerin Interactors

75 Tendai Chisowa PCCM "Characterization of Angiotensin II Signaling in Lung Epithelial Cells"

77 Randy Cruz PCCM Physiological Roles of Olfactory Receptors in Human Airway Smooth Muscle Cells

79 Latasha Easter PCCM Emmisions from Electronic Cigarettes: Is it Really Water Vapor?

81 Carolina Larrain PCCM IL33 and its Receptor, IL1RL1 (ST2), are Genetic Risk Factors and Serum Biomarkers for Pulmonary

Arterial Hypertension

83 Austin Maduka PCCM Understanding the Molecular Basis by Which O-GlcNAc Regulates the Cellular Stress

Response:Identification of the Stress-Dependent Interactome of O-GlcNAcase

85 Stephan Maman PCCM Mechanisms Involved in Hypoxia-inducible Factor 1 Dependent Upregulation of Aquaporin 1

86 Nathaniel Avalos SSSP The Potential Effects of a High-Fat Maternal Diet on the Developing Brain's Oxytocinergic System

87 Lennix Cuffy SSSP Determining Whether the Repetitive Element in the Intron of the G Protein-Coupled Receptor Kinase 4

(GRK4) Gene is Incorporated into mRNA

88 Allison Daitch SSSP Using PCR to Identify Splice Variants in USP28 Associated with Bipolar Disorder and Major

Depression

89 Zita Erbowor-Becksen SSSP Determining the Role of Gut Microbiota in the Pathophysiology of Autism Spectrum Disorders

90 Madiah Gant SSSP Investigation of a Potential Link Between the Oral Microbiota and Psychiatric Disorders: Survey of

Serum Reactivity to Streptococcus pyogenes

91 Morgan Greene SSSP Systemic Immune Activation in Early-Treated Perinatal HIV-Infection

92 Chinezimuzo Ihenatu SSSP The effects of T. gondii on Glutamate Receptors Depends on Age of the Host

93 Emily Krach SSSP Using RT-PCR to Examine Transcriptional Variants Associated with Schizophrenia and Bipolar Disorder

94 Wei Ma SSSP Toxoplasma gondii IP Infection Changes Mouse Intestinal Morphology and Tight Junction Protein

Expression

95 Mishell Manrique SSSP Is exposure to the Pesticide, Bacillus thuringiensis, Associated with the Development of Schizophrenia?

96 Jordan Meyers SSSP Human Gut Microbiota and Psychiatric Disorders: Investigating a Potential Role of Streptococcus pyogenes in the Pathogenesis of Schizophrenia

97 Rachel Walsh SSSP Cigarette Smoking and Smoking Cessation Treatment among Patients Admitted to Sheppard

Pratt Adult Inpatient Programs and Day Hospitals: A Chart Review Study

99 Catherine Acio SIP/BSI Characterizing the Role of Semaphorin 3F Signaling in Neural Plasticity

101 Anna Almario SIP/BSI Genetic Interactions of Histone H2AX with PARP-1 and PARP-2 in DNA Damage Response: Implications

for Cancer Therapy

103 Safiat Ayinde SIP/BSI A Small Molecule-Protein Conjugate for Cancer Immunotherapy

105 Jamar Borland SIP/BSI Characterization of C9orf72 Interacting Proteins by Confocal Microscopy

107 Ariel Calderon SIP/BSI Titin, Lamins and Metabolic Syndrome

109 German Mendoza SIP/BSI Laminar Specific Manganese Enhanced MRI of the Rat Spinal Cord in vivo

111 Jennifer Nguyen SIP/BSI Modulation of Cytochrome P450 Expression by the Hepatitis C Protease Inhibitor Drug Telaprevir in

Primary Mouse Hepatocytes

113 Maeva Nyandjo SIP/BSI The Role of C1q/TNF-related protein-3 (CTRP3) in the Development of Liver Steatosis

115 Michael Olvera SIP/BSI Measurement of CD8+ T Cell Mediated Killing Using Gag Clones from HIV Positive Elite

Suppressors

117 Srikanth Palanisamy SIP/BSI B-adrenergic regulation of ErBB2 protein levels in the heart

119 Ariadne Penalva SIP/BSI Identification of Novel Interacting Partners of Hippo Pathway Component LATS1

121 Ashley Rivera SIP/BSI Antigen Identification in Vaccinated Breast Cancer Patients

Session 2 (3:00-3:50)

# Name Program Title

2 Sarah Marion CSP Nanopore Technology Yields Significant Breakthroughs in Genomic Sequencing

4 Luis Milburn CSP Analysis of VEGF and PlGF Isoform Distributions and Receptor Activation in Computational

Simulations of the Human Body

6 Daniela Perry CSP Statistically Modeling RNA Seq Simulations Comparing Two Isoforms

8 Daniel Rodriguez

CSP The anti-aging gene Klotho as a potential target for mood stabilizers

10 Ariel Sanchez CSP Sub-Cellular Localization of lncRNA in Early B Cell Development

12 Caleb Smith CSP Optimization of Chromatin Immunoprecipitation Protocol in Order to Shear Neural Tissue in Mice

14 Elizabeth

Scriber DASSI Obsessive Compulsive Disorder & Tourettes

16 Marcus Spratley DASSI Obsessive Compulsive Disorder & Tourettes

18 Keon Stalk DASSI Different Treatment Methods for Drug Addiction

20 Lawrence Summerville

DASSI Obsessive Compulsive Disorder & Tourettes

22 D'Kai Vanlandingham

DASSI Public Health

24 Daishia Wilford DASSI Cell Tissue Engineering

26 Abdullah

Williams DAASI Nerve Tissue

28 Adrian Young DAASI Colorectal Cancer

30 Daria Young DAASI Nerve Tissue

32 Rebecca Majeski INBT Methodology to Evaluate the Cellular and Nuclear Uptake of a Polymeric Gene Delivery System

34 Ian Recuroft INBT Release of Sunitinib from Aligned Polylactic Acid Microfibers for the Enhancement of Neurite

Outgrowth

36 Florencia Velez-Cortes

INBT Programmed actuation of photopatterned hydrogel by DNA-crosslink

38 Alexa Wnorowski

INBT In Vitro Turnover of Endothelial Cells

40 Janice Nam JHBIS Differences in Gene expression in painful and non-painful schwannomas

42 Solomon Johnson-Parker

JHBIS Brainwaves during Daily Activities

44 Garnell Purcell JHBIS Protein tracking for mouse acting

46 Anad Rajogopal JHBIS Identificationof genetic variants in children with neurological Disease

48 Tatenda Rameau JHBIS Expression of Osteopontin in Microglia cells in HIV+ Individuals with Cognitive Impairment

50 Shardell Robinson

JHBIS Superficial siderosis Study

52 Dyshae Scott JHBIS Phase II intracranial EEG monitoring for medically refractory epilepsy

54 Rabia Tahir JHBIS Histological characterization of fluorescently labeled outputs of the central amygdala

56 Enza Williams JHBIS Genetic vs. environmental influence on the development of the sleep phenotype circadian rhythm

disorder

58 Amber Young JHBIS Using Mice Models to Analyze Molecular Mechanisms of Alzheimer's Disease

62 Pauline Bagatelas

P-STAR Using immunogenic markers to evaluate inflammation in the cortex of mice infected by

Toxoplasma gondii type 1 strain

63 David Dai P-STAR Locating the Transgene Insertion Site Within the DN-DISC1 Mouse Model

64 Devon Hitt P-STAR Cyst Formation in Mice and Primary Neuron Cultures Due to Toxoplasma Gondii Infection

65 Nicole Rangos P-STAR S-Nitrosylation of NDEL1 mediates activity-dependent dendritic development in the prefrontal

cortex

66 Daniel Wood P-STAR Astrocytes specifically express ALDH7A1 in postnatal mouse brains

67 Rebecca Yang P-STAR Determining the Function of Schizophrenia-Associated Noncoding Variants in CACNA1C

68 Ivonne Martinez PCCM Predictors of Black Carbon and Its Effects on the Health of COPD Patients

70 Jade Miller PCCM Exposure to Heat and Childhood Asthma Morbidity

72 Oscar Paniagua Morales

PCCM Non-small cell lung carcinoma

74 Nicole Parsons PCCM Endobronchial Ultrasound Biopsy With and Without Stylet

76 Gabriel Paul PCCM Airway Extracellular Acidification Responses

78 Jacelyn Peabody PCCM Regulators of Right Ventricular Angiogenesis in a Murine Model of Chronic Hypoxic Pulmonary

Hypertension

80 Brianna Ramirez PCCM Characterizing the ATP Binding Properties of FtsE, a Cell Division Protein, in Caulobacter crescentus

82 Chandramouli Rathnam

PCCM Symptomatic Respiratory Infections are Aggravated by Increased Second Hand Smoke Exposure in

Preschool Children

84 Anna Roland PCCM Serotonin Receptor Density Differences Between Acute Coronary Syndrome And Stable Coronary

Artery Disease Patients

98 Louis Rodgers SIP/BSI

100 Alyssa Rodriguez

SIP/BSI Compensatory kinetic effects of the viscogen and crowding agent PEG8000 on the reaction of human

uracil DNA glycosylase (hUNG)

102 Maribel Santos SIP/BSI Investigating the Hippo Signaling Pathway in Unicellular Organisms, Capsaspora and S. Rosetta

104 Laura Scott SIP/BSI Accumulation of PARIS in a Dopaminergic Cell Line Model Leads to Progressive Impairment of

Mitochondrial Function

106 Alessandra Tomasi

SIP/BSI Differential Production of Type I Interferon between Plasmacytoid Dendritic Cells and Monocytes After

TLR Sensing of RNA Viruses

108 Karina Torres Tristani

SIP/BSI Amygdalo-striatal interaction in the enhancement of stimulus salience in associative learning

110 Alexa Viniotis SIP/BSI Single Nucleotide Polymorphisms (SNPs) in the human IL10 promoter affect gene expression in

macrophages

112 Benedicta Wanjeri

SIP/BSI Determining the Protein Concentration of Malaria Vaccine Candidate Antigen Apical Membrane

Antigen-1 (AMA1)

114 Obinna Wogu SIP/BSI Iodotyroise Deiodinase

116 Nazanin Yeganeh-Kazemi

SIP/BSI Modeling Dilated Cardiomyopathy Using Murine Induced Pluripotent Stem Cells

118 Patrick Yong SIP/BSI Nonsense-Mediated Decay of Hypermutated Proviral HIV-1 RNA

120 Alexandra Berges

SURE Stat3 Regulation in Prostate Epithelial Cells

122 Neil Carleton SURE PBOV1: A Biomarker for Prostate Cancer and Aggression

123 Shohini Ghosh SURE RNA-Seq of Prostate Cancer

124 Mallika Govindan

SURE The role of HOXB13 in prostate cancer

125 Jesse Hall SURE Vascular Remodeling and Calcification of Coronary and Internal Pudendal Arteries from Cadaveric Men

with Cardiovascular Disease.

126 Ross Liao SURE Functional screening identifies miR-21 targets in prostate cancer

Outstanding Students

Savannah Burrell ACCE Academy

DASSI

Shaniya Dwight Paul Laurence Dunbar High School

DASSI

Kahlid Fowlkes Leadership and Initiative Award

Dunbar High School

MERIT

Christiona Harris Outstanding Performance in Clinical Rotations

Milford Mill Academy

MERIT

Devin Mobley Paul Laurence Dunbar High School

DASSI

Savannah Tripp Outstanding Performance in Basic Science Skills Boot Camp

Western High School

MERIT

Acknowledgements

Special thanks to our sponsors for helping make the Hopkins C.A.R.E.S. Summer Symposium a

success: Office of the Vice Dean for Education, Office for Student Diversity, Summer Internship

Program Basic Science Institute, The Johns Hopkins Internship in Brain Science Program, and

Johns Hopkins Schizophrenia Center.

Organizing Committee

Lori Brando, PhD: Assistant Professor and Program Coordinator for Stanley Summer Scholars Program

Amanda Brown, PhD: Director of Johns Hopkins Internship in Brain Science

Chiquita A. Collins, PhD: Associate Dean Office of Diversity and Cultural Competence

Ranice Crosby: Academic Program Administrator for Biophysics for Baltimore Teens

Ashanti Edwards: Academic Program Administrator for Institute for Nano Biotechnology Research Experience for Undergraduates

Sean Foley: High School Program Director, Thread, and Director for Diversity and Academic Advancement Summer Institute

Jasmine Griffin: Office Assistant for Office for Student Diversity

Tahirah Hall: Co Administrative Supervisor for Pulmonary and Critical Care Medicine Summer Internship Program

Eric Lee: Academic Service Specialist for Summer Internship Program

Yukiko Lema: Program Manager for Psychiatry Summer Training and Research Program

Rachelle Lott: Academic Program Assistant for Summer Internship Program

Tyler Mains: Founder and Adviser for Medical Education Initiative for Teens

Vicky Schneider: Center for Talented Youth Program Manager for Center Scholars Program

Jungsan Sohn, PhD: Director of Biophysics Research for Baltimore Teens

Daniel Teraguchi, Ed.D: Assistant Dean for Student Affairs, Director of Office for Student Diversity, Assistant Professor of Pediatrics, Co-Founder of Diversity and Academic Advancement Summer Institute

Emilee Warner: Office for Student Diversity Intern

Mark Wilcox: Co-Founder and Development Director for Medical Education Initiative for Teens

Catherine L. Will: Program Manager for Summer Internship Progra