THE MALE GENITAL SYSTEM

Sri Wiryawan

THE MALE GENITAL SYSTEM

Sri Wiryawan

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1. Internal : a. Testisb. Epididymisc. Deferens ductsd. Seminal glandse. Ejaculatory ductsf. Prostate glandg. Bulbourethral

glands 2. External :

a. Scrotum b. Penis

The Male Genital System

STRUCTURES OF THE MALE GENITAL SYSTEM

INTERSTITIAL CELLS

SEMINIFEROUS TUBULE SEMINAL

VESICLE

PROSTATE

RETE TESTIS PENIS

TUBULUS RECTUS EFFERENT

DUCT

EPIDIDYMIS

DEFERENS DUCT

BULBOURETHRAL GLAND

urethra

TESTIS DUCTS ACCESSORY GLANDS

PENIS

TESTIS

MICROSCOPIC STRUCTURE :

Tunica albuginea Seminiferous tubules Interstitial tissue

Seminiferous tubules 100X

seminiferous tubules

Seminiferous tubule 1000X

lumen with sperm

spermatids

spermatocytes

spermatogonia

sustentacular cell

Interstitial (Leydig) cells

• Loose connective tissue

• Crystals of Reinke

in the cytoplasm

• Secretes testosterone

• Controlled by LH from

pituitary

Sustentacular (Sertoli) cells• Nurse cells.• Extend from basal lamina to lumen.• Connected to each other by tight

junctions Blood-testis barrier.• Nourish spermatogenic cells.• Transport spermatogenic cells.• Phagocytize excess cytoplasm.• Secrete ABP, inhibin, transferrin and

antimullerian hormone (during embryogenesis).

BLOOD-TESTIS BARRIER

SERTOLI-CELL TIGHT JUNCTIONS

BARRIER is carefully controlled to allow the passsage of 10

spermatocytes from basal to adluminal compartments

Adluminal Compartment

Basal Compartment

BLOOD-TESTIS BARRIER

SPERMATOGENESIS

•Spermatositogenesis

•Meiosis : I dan II

•Spermiogenesis

SPERMATOGENESIS

SPERMATOZOON

HEAD

TAIL (flagellum)

NECK

middle piece

Acrosome for digesting zona pellucida

Membrane for recognizing & attaching to Z p

start of Axoneme-microtubular core of tail

Mitochondria as a spiral sheath

coarse Fibrous sheath

principal piece

end piece

highly condensed Nucleus

GENITAL DUCTSGENITAL DUCTSINTRATESTICULAR :INTRATESTICULAR : Tubuli rectiTubuli recti Rete testisRete testis

EXTRATESTICULAR :EXTRATESTICULAR : Eferentes ductsEferentes ducts Epididymis ductsEpididymis ducts Deferens ductsDeferens ducts Ejaculatorius ductsEjaculatorius ducts

DUCTS

DEFERENS DUCTUS

SEMINAL VESICLE

URINARY BLADDER

PROSTATEBULBOURETHRAL GLAND

GLANS

Corpus cavernosum

Corpus spongiosum

URETHRA

SEMINIFEROUS TUBULE

TUBULUS RECTUS

EFFERENT DUCTUS

Ejaculatory duct

RETE TESTIS

PENIS

EPIDIDYMIS

Mediastinum (rete testis)

Seminiferuos tubules

Eferentes duct

Eferentes duct

Epididymis duct

DEFERENS DUCT

ADVENTITIA connecting to other structures of spermatic cord

pseudostratified EPITHELIUM like epididymis’

Thick 3-layered MUSCULARIS int. longitudinal middle circular

out. longitudinal

Small star-shaped lumen

Accessory Genital GlandsAccessory Genital Glands

- - Seminal VesiclesSeminal Vesicles

- Prostate Gland- Prostate Gland

- Bulbourethral Glands - Bulbourethral Glands

(Cowper’s glands)(Cowper’s glands)

SEMINAL VESICLES

ACCESSORY GLANDS

PROSTATE GLAND

Main ALVEOLI

URETHRA

EJACULATORY DUCTS

DUCT - one of many

STROMA (collagen & smooth muscle), making the prostate a self-squeezing gland

CAPSULE

CONCRETION (round, layered)

COWPER’S GLANDS

BULBOURETHRAL GLANDS

P E N I S

PENIS in CROSS-section

Tunica albuginea Superficial dorsal vein

Buck’s fascia

SkinCorpus cavernosum

Urethra

Corpus spongiosum urethrae

Helicine arteries

Veins

Autonomic & sensory nerves

Human Penis (portion) 40X

urethra

corpus spongiosum

collagenous sheath

Human Penis (portion) 40X

corpora cavernosa

venous channels

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