2.2.3 teaching department of biologcal sciences chair ... · 2.2.3 teaching department of biologcal...

2.2.3 Teaching Department of Biologcal Sciences Chair descriptions ACADEMIC CHAIR OF BIOLOGICAL CHEMISTRY Special field: Physical Biochemistry Prof. Dr. J. Polster

Department für Biological Science at the Weihenstephan Scientific Centre of the TU Munich

D- 85350 Freising-Weihenstephan Tel: (0049) 08161 / 71 – 3684 Fax: (0049) 08161 / 71 – 3485 A broad spectrum of lectures is offered on physical chemistry, physical biochemistry, basics of organic chemistry, plant biochemistry and applied biochemistry. Special lectures on photokinetics and the spectroscopic evaluation of chemical systems are also given. Research is applied to theoretical and practical aspects. The unification of titration theory with reaction kinetics using the “Mauser space” is a main aim. Reaction and titration systems are investigated (UV-VIS) spectroscopically and evaluated. In the field of biochemistry, the role of polyphenols (such as catechins) are studied in plant and animal tissues. Research focuses on the localization of these compounds inside cells and their special biochemical roles. CHAIR OF ECOLOGICAL CHEMISTRY AND ENVIRONMENTAL ANALYSIS Weihenstephan Scientific Centre of the Technical University of Munich Weihenstephaner Steig 23 85354 Freising Tel. (++49) 08161 71-3581 Fax (++49) 08161 71-3581 e-mail: [email protected] Kettrup Antonius, Full Professor, Dr. rer. nat., Dr. h.c. The chair offers lectures in general and special ecological chemistry, ecotoxicology and trace analysis of xenobiotics. Training on special topics in the trace analysis of organics is given in practical lab work. Research work focuses on detecting organic pollutants and metabolites in the environment, on reducing emissions by developing clean technologies and detecting harmful substances online, and on environmental risk assessment and risk assessment in work areas.

ACADEMIC CHAIR OF ZOOLOGY Lichtenbergstrasse 4 85747 Garching Tel: (089) 28913660 Fax: (089) 28913674 Email: [email protected] Manley, Geoffrey, University Full Professor, Ph.D., Chairman.

This Chair is responsible for teaching zoology, with an emphasis on neurobiological and ecological courses. Lectures are offered from the basics to the most advanced levels, and are accompanied by the appropriate laboratory courses and field excursions both locally and abroad. Research work concentrates on the neurobiology of the auditory system, behaviour and neural processing in arthropods, the development of the inner ear, and the ecological renaturalization of a local heath. Mandatory Subjects Title Contents Prerequisites Mode of Assessment

Term Hours per week ECTS-Credits Lecturers Literature

Anatomy and histology of animals General introduction. Protozoa. Anatomy and histology of invertebrates and vertebrates (Cnidaria, Plathelminthes, Annelida, Mollusca, Acrania, Pisces, Amphibia, Mammalia). Dissection, tissue study.

Written final test

Winter semester only 5 5 Prof. Dr. Franz Peter Fischer, Dr. Hort Oeckinghaus, Dr. Michael Gebhardt, Prof. Dr. Geoffrey A. Manley. Some materials available on the web. Refer to: Storch, Welsch: KÜKENTHAL, ZOOLOGISCHES PRAKTIKUM, Spektrum-Verlag 1999

Title Contents Prerequisites Mode of Assessment Term Hours per week ECTS-Credits Lecturer Literature

Applied Biochemistry (Technical Biology) Enzymatic analysis in medicine, food technology and microbiology, derivation of the basic equations of absorption and fluorescence spectroscopy, enzymatic mechanisms, determination of enzyme activity, enzyme kinetics, the first theorem of kinetics, basics of bioenergetics, biosensors, optodes, data evaluation on the basis of neural networks and fuzzy logic, animal-organ-cell-systems, ligand-receptor interaction, receptor affinity + activity, second messenger, vertebrate hormone systems, in vitro versus animal experiments, animal law, receptor assay, molecular assay system (ELISA, PCR), reporter gene assay, sex differentiation, mammalian immune systems, antibodies, immunization, antibody production (mono + polyclonal), immunological techniques (RIA, FACS, histology), allergies, vaccination, autoimmune reactions Basics in general chemistry and biochemistry Oral WS 2 3 Einspanier / Pfaffl / Polster Copies to be distributed

Title Contents

Prerequisites Mode of Assessment

Comparative Animal Physiology Introduction. Neurophysiology, synapses. Information processing in the central nervous system. Sensory physiology. Muscle physiology. Nutrition and energy. Excretion, Water balance. Respiration and circulation. Temperature control. Hormones and behaviour. Biorhythms.

Lecture course on introduction to zoology. Written

Term Hours per week ECTS-Credits Lecturer Literature

Summer semester only 4 6 Prof. Dr. Geoffrey A. Manley, Prof. Dr. H.-J. Leppelsack Eckert, Tierphysiologie or similar


Diversity and Biology of Local Animals General introduction. Pisces, Amphibia, Reptilia, Aves, Mammalia, Insects, Crustacea, Arachnida. Excursions Written final exam Summer semester only 4 4 Prof. Dr. Franz Peter Fischer, Dr. Hort Oeckinghaus, Dr. Michael Gebhardt, Prof. Dr. Geoffrey A. Manley Some materials available on the web.


Ecology General introduction. Environmental factors, resources, autecology, demography, population dynamics, population structure, migration, competition, predator-prey systems, pest control, mutualism, parasitism, ecosystems, biogeography.

Written final exam Summer semester only 2 3 Prof. Dr. Franz Peter Fischer Some materials available on the web. Refer to: - Begon, Harper, Townsend: ÖKOLOGIE, Spektrum-Verlag 1998

Title Contents Mode of Assessment Term Hours per week ECTS-Credits Lecturer Literature

Environmental Chemistry and Ecotoxicology for Civil Engineers The topics of the lecture course are

- sources and sinks for chemicals - migration, immobilisation and degradation processes of

chemicals in the environment - bioaccumulation and food chains - effect monitoring - environmental specimen bank - environment protection - product and process integrated environment protection

Written SS 1 1.5 Kettrup

- Korte : Ökologische Chemie

- Schwedt: Taschenatlas der Umweltchemie

Title Contents Mode of Assessment Term Hours per week ECTS-Credits Lecturer Literature

General Zoology General introduction. A sketch of the structure, evolutionary history and life styles of the following phyla: protozoa; porifera; coelenterata; plathelminthes; annelida; mollusca; nematoda; arthropoda; echinodermata; hemichordata; chordata. A discussion of the following general themes: evolution; ontogeny; ecology; behaviour; physiology of the nerves, senses, hormones and muscles Written final exam WS only 4 6 Prof. Dr. Geoffrey A. Manley Some materials available on the web. Refer to: - Wehner, Gehring: ZOOLOGIE, Thieme; - Mehlhorn: GrundrIß der Zoologie, Fischer; Campbell, BIOLOGIE, Spektrum-Verlag 1997

Title Contents Prerequisites Mode of Assessment Term Hours per week

One-day Zoology Excursions Observation and classification of different invertebrate and vertebrate animal species and of protists in different biotopes Summer semester only

ECTS-Credits

Lecturer Literature

0.5 Associated with the course ‘Classification of Animals’ Prof. F.P. Fischer, Dr. M. Gebhardt, Prof. R. Gerstmeier, Prof. H.-J. Leppelsack, Dr. H. Oeckinghaus, Dr. U. Sienknecht

General Optional Subjects Title Contents Prerequisites Mode of Assessment Term Hour per week ECTS-Credits Lecturer Literature

Advanced Laboratory Course in Zoology (1) Histological and microscopical techniques. Histological structure of the organs and tissues of vertebrates and invertebrates. Introduction to animal development and embryology. Histological observations and processing of developmental stages in different vertebrates and invertebrates. Dissection and microscopical observations of annelida, hemichordata. Echinodermata, tunicata, cyclostomata, and fetal pigs.

Lectures “Zoology of Vertebrates” (No. 30268) and “Zoology of Invertebrates” (No. 30074) Written final exam Winter semester only 25 25 Dr. H. Oeckinghaus, Prof. G.A. Manley, Dr. M. Gebhardt, Dr. U. Sienknecht, Dr. L. Bally-Cuif Materials are handed out during the course. Refer to Campbell: „Biologie“


Advanced Zoological Laboratory Studies II, Compulsory part. This is the introductory section for all students taking Advanced Zoological Laboratory Studies II. An introduction to common methods of computer-supported data analysis, statistics, data presentation and report writing. This includes an introduction to the use of the following software: Winword, Excel, Powerpoint, SPSS statistics, WWW-browser. Literature research and administration. Following demonstrations each morning, there are practice sessions to discuss specific problems each afternoon. Foundation studies (“Vordiplom”) or Bachelor, animal physiology. Preferred: Long practical 1, neurobiology. Report at the end of the third week. Winter semester only 11 as a 3-week block, no parallel practicals are possible. 11 PD Dr. C. Köppl, Prof. Dr. Geoffrey A. Manley. No special literature.

Title Contents Prerequisites Mode of Assessment


Advanced Zoological Laboratory Studies II, research blocks. These research blocks involve participation in the research of the various zoological laboratories and the actual project carried out will depend on the laboratory chosen. The aim is to give participants an insight into the background, problems and techniques used to solve a research problem. Participants will have hands-on exposure and will be involved in carrying out part of a current research project. In some cases, research participation in other laboratories may be accepted as equivalent. Foundation studies (“Vordiplom”) or Bachelor, animal physiology. Preferred: Long practical 1, Neurobiology. One week after each research block has ended, a report must be submitted for evaluation. Winter semester only Offered as a 4-week block, no parallel practicals are possible 7 Prof. Dr. Geoffrey A. Manley, Prof. Dr. H.-J. Leppelsack, apl.-Prof. Dr. F.P. Fischer, PD Dr. Christine Köppl, Dr. Ulrike Sienknecht, Dr. H. Oeckinghaus, Dr. M. Gebhardt.. Original research literature will be handed out.


Advanced Zoological Laboratory II, Seminar This seminar provides an opportunity for students taking Advanced Zoological Laboratory Studies II to present the theme of their research block both in the planning stage, before the block, and afterwards, to discuss their results. Some of the presentations will be in English. Participants generally work in teams of two.

As for Advanced Zoological Laboratory Studies II, Compulsory part. Based on the presentation and basic understanding of the topics Winter semester only 2 2 Prof. Dr. Geoffrey A. Manley, Prof. Dr. H.-J. Leppelsack, apl.-Prof. Dr. F.P. Fischer, PD Dr. Christine Köppl, Dr. Ulrike Sienknecht, Dr. H. Oeckinghaus, Dr. M. Gebhardt. Original research literature will be handed out.

Title Contents Prerequisites Mode of Assessment Term Hours per week ECTS-Credits

Current Topics in the Evolution, Morphology and Function of Hearing Organs The seminar covers various recently published advances in research into the hearing organs of vertebrates. The emphasis is on topics related to evolution, morphology, development and function.

Both winter and summer semester 2 2

Lecturer Literature

Prof. Dr. G.A. Manley, Prof. Dr. F.P. Fischer, PD Dr. Christine Köppl, Dr. Ulrike Sienknecht, Dr. H. Oeckinghaus. Recent research articles will be provided.


Current Topics in Invertebrate Biology This seminar is meant for students with a general interest in invertebrate biology and covers various recently published advances in this field. The emphasis is on behavioural, neurobiological and developmental topics. Apart from this, presentations of the current research topics of our labs are given.

From the 5th semester onwards. A literature presentation. Both winter and summer semester 2 2 Prof. Dr. B. Schmitz, Dr. Michael Gebhardt Recent research articles will be provided at least one week before the seminar.


Ecological Chemistry I: the Fate of Chemicals in the Environment The production of chemicals and redistribution of natural compounds lead to local concentrations that can be harmful for organisms or can disturb environmental processes. Special topics: sources and sinks, metabolism, transport, accumulation, biomagnification and food chains, mobility, remobilization, persistence, abiotic transformation by photochemistry, modelling distribution of compounds indoors Fundamentals of chemistry and biology Written WS 1 1.5 Kettrup, Spitzauer

- Schwedt: Taschenatlas der Umweltchemie - Korte: Ökologische Chemie

Title Contents

Prerequisites Mode of Assessment

Ecological Chemistry II: Basic Topics in Ecotoxicology

- Effects of chemicals on organisms and inorganic matter in ecosystems,

- exposition - toxicity, teratogenicity , cancer inducing activity,

mutagenicity, estrogeneous and androgeneous effects - trace gases and climatic change - environment protection: indoors, outdoors, working area - instruments of environmental diagnosis - environmental quality standards - regulation through federal laws

Ecological chemistry I Written


SS 1 1.5

Kettrup, Spitzauer

- Korte : Ökologische Chemie - Greim/Deml: Toxikologie - Fent: Ökotoxikologie - Eisenbrand/Metzler: Toxikologie für Chemiker


Ecology of Flowing Water General introduction. Aquatic ecosystems, water quality. Mollusca, ephemeroptera, trichoptera, coleoptera, diptera etc., Excursions, field work Written final exam Summer Semester only 2 4 Prof. Dr. Franz Peter Fischer Some materials available on the web. Refer to: - Schönborn: FLIESSGEWÄSSERBIOLOGIE, G.-Fischer-Verlag 1992, Wasserwirtschaftsamt: Schlüssel zur Bestimmung der DIN-Arten, Eigenverlag 1988


Exercises in Basics of Trace Analysis Exercises in lab ‘from environmental sample to assessment of organic residues’: - sample preparation and clean up

- separation of compounds in sample extract - identification by spectroscopic array - quantitative assessment -

Basic topics in residue analysis (covered in lectures) Written WS

1 (2.5 days teaching by topics) 1.0 Martens

Title Contents

Prerequisites Mode of Assessment Term Hours per week ECTS-Credits Lecturer Literature

Exercises in Ecological Chemistry Supplementary seminar course for ‘Ecological Chemistry I + II’ . Students have to give seminar papers on various eligible topics such as

- exposition of human beings - heavy metals, solvents, radioactive elements, aerosols,

sulphur dioxide in the air - indoor chemicals like formaldehyde, insecticides, fungicides- monitoring organisms - the role of volatile organic carbons in climatic change - contamination of special food, drinking water or breast milk- purification techniques for drinking water, air, soil - testing systems for new chemicals

Ecological chemistry I Written WS 2 2 Spitzauer

- Korte : Ökologische Chemie - Fent: Ökotoxikologie - Schwedt: Taschenatlas der Umweltchemie - Heintz/Reinhardt: Chemie und Umwelt - Bliefert: Umweltchemie - Parlar/Angerhöfer: Chemische Ökotoxikologie

Title Contents

Prerequisites

Mode of Assessment Term Hours per week ECTS-Credits Lecturer Literature

Experimental course in Ecological Chemistry/ Ecotoxicology for Students of Biology and Chemistry This course gives students the opportunity to collaborate in actual research outdoors together with members of staff. The results collected over a 4-week period must be presented as a draft paper Ecological Chemistry I + II; Basic trace analysis topics; Exercises in basics of trace analysis Draft paper

WS / SS

8

8

Kettrup, Martens, Spitzauer


Impact of Pollutants on Air, Water and Soil This lecture course covers basic topics in ecological chemistry:

- sources, sinks, distribution and transport of chemicals in the environment

- biotic and abiotic transformation of compounds in air, water and soil

- life cycle studies of compounds - national and global case studies

SS

1 1,5 Schmitt-Kopplin


Laboratory Course in Animal Physiology The experimental study of animal (invertebrates) and human physiology; experiments in muscle, neuro, sensory, cardiac, and circulatory physiology.

Lecture course “General Zoology” Written final exam Summer semester only 4 4 Dr. H. Oeckinghaus, Dr. U. Sienknecht, Dr. M. Gebhardt,

- Klinke, Silbernagel: „Lehrbuch der Physiologie“. - Eckert: „Tierphysiologie“.

Title Contents Prerequisites Mode of Assessment Term Hours per week ECTS-Credits

Neurobiology General introduction. The basics of membrane physiology. Membrane ionic channels. The physiology of synapses. Transmitters and modulation. Integrative processes in the central nervous system. Memory. Sensory physiology. Principles of the development of the nervous system. Epigenetic effects on CNS development. Animal Physiology. Long practical 1 preferred Written final exam Summer semester only 4 6

Lecturer Literature

Prof. Dr. Geoffrey A. Manley, Prof. Dr. H.-J. Leppelsack; PD Dr. C. Köppl - Dudel, J, Menzel, R, Schmidt, R., Neurowissenschaften, 2001 or similar


Mediterranean Fauna General introduction. Mediterranean land and marine fauna Practical diversity and biology of indigenous animals SS only 5 5 Prof. Dr. Franz Peter Fischer Some materials available on the web. Refer to: - Hofrichter: DAS MITTELMEER, Bd. 1-3, Spektrum-Verlag 2001, 2002

Title Contents Prerequisites

Plant Biochemistry (Students of Biochemistry, Molecular Biotechnology and Biology) Secondary plant metabolism, ketolase and aldolase reactions, shikimate pathway, membrane transport processes, phenolic acids, cell wall, monolignols, lignin, flavonoids, chalkone synthase, flavan-3-ols (catechins), tannins, co-pigmentation, biosynthesis of purines and pyrimidines, tetrapyrroles, biosynthesis of chlorophyll, flavines and pteridines, isoprenoids, DOXP pathway, mono-, di- and triterpenes, saponins, steroid alkaloids, carotinoids, caoutchouc, phytohormones, alkaloids Basic lectures in biochemistry

Mode of Assessment Term Hours per week ECTS-Credits Lecturer Literature

Written SS 2 3 Elstner / Grill / Polster


Seminar for Thesis Students This seminar provides an opportunity for students who are currently working on their dissertation or Master’s thesis to present their research theme, approach, results and problems. The goal is to provide a forum in which the faculty present can give advice to the students in order to optimize their progress, solve problems, and avoid potential pitfalls. Both winter and summer semester 2 2 Prof. Dr. G.A. Manley, apl. Prof. Dr. F.P. Fischer, PD Dr. Christine Köppl, Dr. Ulrike Sienknecht, Dr. H. Oeckinghaus, Dr. M. Gebhardt


Seminar in Marine Biology Flora and fauna, ecology and human influence of marine ecosystems, with an emphasis on the Mediterranean Sea Winter semester only 2 2 Prof. F.P. Fischer - Hofrichter: “Das Mittelmeer”.


Special Zoology 1: Protostomia General introduction. Protozoa, placozoa, spongia, cnidaria, plathelminthes, nemathelminthes, smaller phyla, mollusca, annelida, arthropoda,

Written final exam Winter semester only 2 3 Prof. Dr. Franz Peter Fischer, Dr. Horst Oeckinghaus, Dr. Michael Gebhardt Some materials available on the web. Refer to: - Storch, Welsch: SYSTEMATISCHE ZOOLOGIE, G.-Fischer-Verlag 1997


Zoological Seminar in the English Language. These seminars offer an alternative to other zoological seminars in that all procedures are carried out in English. Not only is the literature in English, the students each hold at least one talk on a zoological theme in English and all discussion is held in English. Students thus have the opportunity to improve their language skills. Participants receive constructive criticism both on their presentations and on their language usage. A medium level of skill in the English language is necessary. Presentations. Summer semester only. 2 2 Prof. Dr. G.A. Manley. Appropriate literature is provided, but students may suggest alternative topics.

Optional Subjects Title Contents Prerequisites Mode of Assessment Term Hours per week ECTS-Credits Lecturer Literature

Basic Topics in Trace Analysis This lecture offers an introduction to residue analysis: - Separation and identification of chemicals by GC, HPLC, IC, CEC, GC-MS - Identification by spectroscopic methods: VIS, UV, IR, NMR, MS, HPLC-MS, GC-MS - AAS, AES, ICP, hydrid-AAS - Selection of samples representing a special situation - Clean-up methods Written WS 1 1.5 Martens

- Schwedt: Taschenatlas der Analytik

Title Contents Prerequisites Mode of Assessment

Ecological Case Studies This seminar course supplements the “Exercises in Ecological Chemistry”, covering other topics and aspects (e.g. “production of chemicals during fire”, “oil spill”, “accident in a industrial chemical plant”)

Ecological Chemistry I + II


SS 1 1,5 Spitzauer


Environmental Pollution Analysis Using Biochemical Methods This lecture course gives an overview of biochemical methods available for the analysis of environmental pollution. The topics are as follows: environmental matrices and analytes relevant for environmental analyses; acetylcholine esterase inhibition test; EROD-test; immuno-assays (test-kits), immuno-sensors; bio-sensors; tests based on receptors; tests based on micro organisms (key word: BOD); algae tests; lumitox test; yeast test system. In addition, the criteria of validation is discussed, focusing on immuno-assay test-kits. Written WS 1 1.5 Krämer


Environmental Protection Technology These lectures cover various technologies in environmental protection for reducing gaseous, liquid or solid emissions. It presents ecotoxicological parameters suitable as testing systems in the contamination of food or other products. Written WS 1 1.5 Schramm


PhD Students’ Seminar on Ecological Chemistry Seminar course on current topics in lab work

WS, SS 1 1,5

Kettrup, Martens, Spitzauer - Korte : Ökologische Chemie - Schwedt: Taschenatlas der Umweltchemie


Practical and Theoretical Radiological Techniques in Ecological Chemistry These lectures present an introduction to the detection and measurement of radioactivity in samples from the environment:

- �-,�-,�-radiation - natural and other radioactive isotopes - doses and danger - modelling of ‘carry over’ (soil to plant) and ‘transfer’ (plant

to animal/human) - transport of radioactive material in the atmosphere - wet and dry deposition

Ecological Chemistry I Written WS 1 1.5 Voigt


Results and Problems of Bioindication In this seminar course, an introduction is given to general aspects of terrestrial biomonitoring, e.g. - active or passive exposition of test organisms - monitoring of accumulation or effects of selected compounds in/on plants and animals - comparison of ‘effects on living organisms’ with ‘data from measuring instruments’ - problems in data interpretation Students have to present seminar papers on special topics. Ecological Chemistry I + II 1 1,5 Spitzauer


Risk Assessment of Chemicals in the Environment This lecture course gives an introduction to risk modelling. The specific data of compounds and molecular modelling are presented as a basis for modelling exposure of human beings, integrating predictions of the transport of chemicals in the atmosphere, hydrosphere, soil and biosphere. This modelling of exposure is linked to forecast modelling of toxicity. Both topics give an idea of risk modelling. Ecological chemistry I + II SS 1 1 Schramm

Title Contents Prerequisites Mode of Assessment Term

Quantitative Analysis of Spectroscopically Investigated Biological Systems (Biophysics, Biology, Agricultural and Horticultural Sciences) The three theorems of the spectroscopic-kinetic analysis of reaction systems, the theory of linear and non-linear reaction systems, the “Mauser space”, approaches to combining titration theory and reaction kinetics, fundamentals of photokinetics, partial quantum yield, the relationship between quantum yield and the reaction mechanism, spectroscopic analysis of (quasilinear) photoreactions on the basis of absorption and fluorescence spectroscopy. Basics in general chemistry WS

Hours per week ECTS-Credits Lecturer Literature

2 3 Polster Copies


Selected Problems in Radioecology: Remediation Strategies This seminar course offers an introduction to strategies for combating radiation effects on both temporal and spatial scales, and gives an idea of the prospects of success of the strategies. Students present seminar papers based on international literature and discuss it. SS 1 1.5 Voigt

Title Contents

Sensors and Bioprocess Control This lecture course gives an overview of biosensors and includes the following topics: definition and characteristics of biosensors, development of biological recognition elements, immobilisation, principles of transducers (electrochemical, optical, piezoelectric, etc.), enzymes, antibodies and nucleic acids in biosensors and bioprocess control (examples), automation (flow injection analysis), commercial biosensors (examples of instruments and test-kits) and as of summer 2002, also MIPs (molecularly imprinted polymers). A list of relevant literature is provided for each chapter, which includes text books and original papers.

Prerequisites Mode of Assessment Term Hours per week ECTS-Credits Lecturer Literature

Written SS 1 1.5 Krämer

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