RegisteR by JanuaRy 14 foR eaRly-biRd pRicing

TO REgISTER: Call 866-207-6528 or visit us at www.exlpharma.com

Conference Chair:Craig Lipset, Senior Director (Clinical Research) and Venture Partner (Pfizer Venture Investments), PFIZER

2nd Patient Engagement Summit: New Technologies for Engaging Patients in Clinical TrialsImplementing Cutting Edge Communication Technology to Facilitate Recruitment, Compliance, and Retention in Clinical Trials

Proudly Presents:

MARCH 1-2, 2011CROWNE PLAzA PHILADELPHIA DOWNTOWN

our Esteemed Speaker Faculty:Craig Lipset Senior Director (Clinical Research) and Venture Partner (Pfizer Venture Investments), PFIZERDavid Leventhal Director, Healthcare Informatics, PFIZERgretchen goller Patient Recruitment/Compliance Strategist-Operations, SANOFI-AVENTISKaren Brooks Director, Clinical Projects, SANOFI-AVENTISLinda DealDirector, Patient Reported Outcomes, JOHNSON & JOHNSONLynn Sutton Vice President, Clinical Services, ALLOS THERAPEUTICSMats Sundgren Principal Scientist, Global Clinical Development, ASTRAZENECAMelanie goodwin Manager, Global Trial Optimization, MERCKMiguel Orri Senior Director, PFIZERJoseph Kim Director of Clinical Operations, SHIRE PHARMACEUTICALSLisa Kaufman Director, Clinical Operations, MERSANA THERAPEUTICSPetra Jaeger Clinical Operations Group Head Quality & Training, NOVARTIS PHARMACEUTICALS GMBH

TO REgISTER: Call 866-207-6528 or visit us at www.exlpharma.com

Featured Presentations:PFIzER CASE STUDY: ONLINE CLINICAL TRIALEarly Look at Pfizer’s Unprecedented Study—the First Clinical Trial to Exclusively Use Online Recruitment, a Web-Based Informed Consent Process, and Virtual Follow-Up for Patient Engagement Miguel Orri, Senior Director, Clinical Sciences (Primary Care Business Unit), PFIZER

CASE STUDY: ONLINE COMMUNITIESCreating and Nurturing Patient Driven Online Communities to Validate Interest in Study ParticipationLynn Sutton, Vice President, Clinical Services, ALLOS THERAPEUTICS

MERCK’S “CENTER OF EXCELLENCE” ON gAININg INTERNAL BUY-IN: Preparing the Internal Team for a Study Using Tools of the 2.0 Age so Your Trial’s Clinical Data is Processed in a Timely MannerMelanie Goodwin, Manager, Global Trial Optimization, MERCK

ePRO CASE STUDY: DEVELOPINg AND VALIDATINg A DAILY ELECTRONIC ENDOMETRIOSIS PAIN AND BLEEDINg DIARY (EPBD)Advances in Electronic Patient Reported Outcomes (ePRO) that Increase Accuracy and Improve Compliance in Clinical TrialsLinda Deal, Director, Patient Reported Outcomes, JOHNSON & JOHNSON

Utilizing Electronic health Records To More Efficiently identify Potential Trial ParticipantsA PAN EUROPEAN CASE STUDY: The Benefits of the Innovative Medicine Initiative’s EHR4CR Project, which Shares Information Between 32 Partners—Including 10 Pharmaceutical Companies— Across Multiple NationsMats Sundgren, Principal Scientist, Global Clinical Development, ASTRAZENECA

PACeR CASE STUDY: The Advantages of New York State’s EHR Clinical Trials NetworkDavid Leventhal, Director, Healthcare Informatics, PFIZER

Sponsored by:

hotel informationOur Philadelphia hotel’s location puts you in the heart of the city. Visitors can enjoy everything from the famous Philadelphia Cheesesteak to the Liberty Bell. No matter what your interests, Philly is the city that has it all. Crowne Plaza Philadelphia Downtown offers modern accommodations with gracious amenities surrounded by Rittenhouse Square, fine dining, Walnut Street shopping and treasured historic attractions.

Room ReservationsIf you require overnight accommodations, please contact the Crowne Plaza Philadelphia Downtown at 215-561-7500 to book your room. ExL has reserved a block of rooms at a discounted rate for con-ference participants. Please mention ExL Pharma and the conference name to take advantage of the discount. You must book your room by Monday, February 7, 2011 to be eligible for the discounted rate. Please book your room early, as the rooms available at this rate are limited.

TO REgISTER: Call 866-207-6528 or visit us at www.exlpharma.com

Who Should attend:Directors, Managers, Heads, Vice Presidents and Coordinators of:

◆ Patient Recruitment◆ Trial Optimization◆ Clinical Trials◆ Clinical Research◆ Clinical Development◆ Clinical Data Management◆ Clinical Information Systems◆ ePRO (electronic patient

reported outcomes)◆ Clinical Projects◆ Clinical Operations◆ Clinical Studies

◆ Healthcare Informatics

You will also meet representatives from:

◆ Sites◆ Regulatory Groups◆ Non-profits◆ Universities◆ Advocacy Groups/

Online Communities◆ Recruitment/Retention Agencies◆ CROs ◆ Consultancies

Dear Colleague,This is an exciting time for recruiting patients into clinical trials and engaging them throughout. New technologies such as online screening and EHRs allow clinicians to reduce recruitment time. Social media and mobile devices allow sites to more closely monitor behavior and work with patients and family members to increase compliance. Technologies that ease communication are allowing study leaders to keep in close contact with patients after the study is complete.

As more pharmaceutical companies crack the code about how to successfully use new technologies to meet deadlines, clinical trials leaders must maintain a keen awareness of what tools are available, or risk falling behind competitors who more quickly recruit patients and more effectively engage them to avoid attrition.

Exl’s 2nd Patient Engagement Summit: New Technologies for Engaging Patients in Clinical Trials is your opportunity to be part of a highly quali-fied group of clinical trial leaders looking to make informed decisions about acquiring and integrating new technologies that will help meet deadlines and improve study effectiveness.

Sincerely,

Dave HoffmanDave Hoffman Kristen HunterConference Director Team Leader, Production2nd Patient Engagement Summit: ExL PharmaNew Technologies for Engaging Patients in Clinical Trials

Sponsorship and Exhibiting opportunitiesDo you want to spread the word about your organization’s solutions and services to potential clients who will be attending this event? Take advantage of the opportunity to sponsor, underwrite an educational session, host a networking event, or distribute promotional items to attendees. ExL Pharma will work closely with you to customize a package that suits all your needs. To learn more about these opportunities, please contact Eric Morrin at (212) 400-6228, or emorrin@exlpharma.com.

1:00 Chairperson’sWelcomeandOpeningRemarks

Craig Lipset, Senior Director (Clinical Research) and Venture Partner (Pfizer Venture Investments), PFIZER

iNTERNal BUY-iN1:15 PreparingtheInternalTeamforaStudyUsingToolsofthe2.0 AgesoYourTrial’sClinicalDataisProcessedinaTimelyManner

Melanie Goodwin, Manager, Global Trial Optimization, MERCK• Getting buy in from study team members using new patient engage-

ment tools and techniques• Effectively interacting with 2.0 patients by developing a “patient

centric” mindframe• Evaluating study goals and technology options to help meet

benchmarks

UTILIzINg ELECTRONIC HEALTH RECORDS TO MORE EFFICIENTLY IDENTIFY POTENTIAL TRIAL PARTICIPANTS

a PaN EURoPEaN CaSE STUDY2:00 TheBenefitsofInnovativeMedicineInitiative’sEHR4CRProject

Mats Sundgren, Principal Scientist, Global Clinical Development, ASTRAZENECA• Reducing recruitment time by a potential factor of 10 with a new

multi-country EHR sharing project• How the project handles de-identification, legal, and ethical issues• Understanding the business model and how it addresses technical

and semantic issues of sharing information between 32 partners – including 10 pharmaceutical companies – across multiple nations

2:45 NETWORkINg&REfRESHMENTBREAk

PaCeR CaSE STUDY3:15 TheAdvantagesofNewYorkState’sEHRClinical TrialsNetwork

David Leventhal, Director, Healthcare Informatics, PFIZER• Overview of the New York State Partnership to Advance Clinical

Electronic Research (PACeR) Collaborative• Adjusting protocols based on information in the EHR clearinghouse• Using EHRs to target geographic areas containing appropriate

patients for site selection

RoUNDTaBlE DiSCUSSioNS4:00 AudienceMemberswillSplitintoSmallergroupsfor InteractiveDiscussionsonkeyIssues

Participantschoosefromthefollowingtopics:

1.ETHICS: What Ethical Issues should be considered in Social Media and Mobile Technology

2.LEVELOfENgAgEMENT:Can Client Engagement Become too Invasive and Discourage Enrollment?

3.MININgONLINEDATA: Reducing Time in Finding Qualified Study Patients by Using Online Communities, Networks, and Advocacy Groups

4.ONLINECOMMUNITIES: Creating and Nurturing Patient Driven Online Communities to Validate Interest in Study Participation

5.VIRTUALSCREENINg Using a Trial Specific Website for Online Screening to Increase Efficiency in Recruitment

6.EPRO: Advances in Electronic Patient Reported Outcomes (ePro) that Increase Accuracy and Improve Compliance in Clinical Trials

Moderatorsinclude:Petra Jaeger, Clinical Operations Group Head Quality & Training, NOVARTIS PHARMACEUTICALS GMBH Linda Deal, Director, Patient Reported Outcomes, JOHNSON & JOHNSONJoseph Kim, Director of Clinical Operations, SHIRE PHARMACEUTICALS

5:00 DAYONECONCLUDES

DaY oNE • Tuesday, March 1, 2011PRE-CoNFERENCE WoRKShoP – ThE PaTiENT CENTRiC aPPRoaCh9:00 BetterEngagingClinicalTrialsParticipantswitha“PatientCentric”Approach,andHowTechnologyCanHelpYouInteract inPatients’MostComfortableSetting

Lisa Kaufman, Director, Clinical Operations, MERSANA THERAPEUTICSPatients in the 21st Century will no longer accept being viewed as “subjects” to be studied. The spirit of the internet era dictates that patients expect to be viewed as partners in all endeavors, especially when it comes to their health. Sponsors that stick to old methods will be left behind as competitors adopt new technologies to recruit patients, facilitate compliance, reduce attrition, and follow up in a way that increases quality assurance for future trials. This workshop will review not only what new technologies are available, but how to approach patients in a way that best allows for speedier recruitment and more thorough engagement throughout.• Instilling a “patient centric” mindframe into clinicians, both internal and on site• How patients view trial sponsors, and how to make that work when recruiting through online communities• The newest technology available for mobile devices, and a review of appropriate uses of text messaging reminders to patients and their support systems

10:30 NETWORkINgANDREfRESHMENTBREAk

12:00 WORkSHOPCONCLUDES;LUNCHfORWORkSHOPATTENDEES

MaiN CoNFERENCE BEGiNS

8:30 Chairperson’sRecapofDayOneandRoundtableDiscussions

Craig Lipset, Senior Director (Clinical Research) and Venture Partner (Pfizer Venture Investments), PFIZER

ExECUTiVE PaNEl DiSCUSSioN9:00 SharingExperiencesinBuildingaResearchCulturethat EncouragesTrialSponsorstoEmbraceNewPatient EngagementTechnologies

Moderator:Joseph Kim, Director of Clinical Operations, SHIRE PHARMACEUTICALSPanelists:Karen Brooks, Director, Clinical Projects, SANOFI-AVENTISMats Sundgren, Principal Scientist, Global Clinical Development, ASTRAZENECA• Overcoming practical barriers to acceptance of new technology• Altering or addressing habits of colleagues with entrenched patient

engagement practices• Handling unexpected challenges that occur when new technologies

are adopted to avoid inadvertently slowing down the recruitment process

oNliNE aDVERTiSiNG9:45 UsingOnlineAdvertisingforTotalMarketPenetration andtoTargetDifferentDemographicsandEnsureEnrollment DeadlinesareMet

Joseph Kim, Director of Clinical Operations, SHIRE PHARMACEUTICALS• The goals of online advertising versus traditional advertising in

recruitment and education• What additional patients can be reached using web based advertising• The limitations of online advertising as a tool for recruiting patients

10:30 NETWORkINg&REfRESHMENTBREAk

PFiZER CaSE STUDY11:00 EarlyLookatPfizer’sUnprecedentedStudy–thefirstClinical TrialtoExclusivelyUseOnlineRecruitment,aWeb-Based InformedConsentProcess,andVirtualfollow-UpforPatient Engagement

Miguel Orri, Senior Director, Clinical Sciences (Primary Care Business Unit), PFIZERLessons learned in sourcing and consenting trial patients online

• Overcoming the legal challenges in the 50 “United” States• Best practices in having patients self report study results

using electronic correspondence and mobile devices• Pioneering demonstration to remotely monitor patient safety using

a centralized PI• Unprecedented follow up with the patients after the trial ends

NoVEl TEChNoloGY ShoWCaSE aND FoCUS GRoUP11:45 AseriesofMiniPresentationsPremieringtheNewest AdvancesinEmergingandCuttingEdgeTechnologySolutions forRetention,Compliance,andRetention

• The Valuable Role of the Technology ◆ The Right Type of Study ◆ The Right Patient Type• The Best Approach for Implementing• Followed by Audience Feedback and QuestionsIfyouareininterestedinparticipating,pleasecontactEricMorrinat(212)400-6228

12:30 LUNCHEON

CaSE STUDY: oNliNE CoMMUNiTiES1:30 CreatingandNurturingPatient-DrivenOnlineCommunities toValidateInterestinStudyParticipation

Lynn Sutton, Vice President, Clinical Services, ALLOS THERAPEUTICS• Understanding interactivity as a tool to encourage participation• Managing confounding factors of patient communication in existing

independent communities• Encouraging compliance through effective site moderation• Building an online patient community from scratch

ePRo CaSE STUDY2:15 DevelopingandValidatingaDailyElectronicEndometriosis PainandBleedingDiary(EPBD)toIncreaseAccuracyand ImproveComplianceinClinicalTrials

Linda Deal, Director, Patient Reported Outcomes, JOHNSON & JOHNSON• Developing and validating an EPBD for assessing patient reported

treatment related changes in endometriosis symptoms • A review of study methodology, including focus groups and

cognitive interviews• Study outcome, and areas for further research

MoBilE TEChNoloGY3:00 IncreasingPatientCompliancebyUsingMobileTechnology asanEngagementTool

Gretchen Goller, Patient Recruitment/Compliance Strategist-Operations, SANOFI-AVENTISJudith Teall, Director of Patient Recruitment, EXCO INTOUCH• The importance of establishing good communications with the patient• Combining the use of automated text messages and emails to most

effectively enable and encourage patients to continue within the study and remain compliant

• Facilitating family and support network engagement through mobile technology that can transmit reminders and behavioral reports

PaNEl: RUlES oF ENGaGEMENT3:45 StrategiesforOvercomingRegulatoryBarriersin PatientCommunication

Moderator:Daniel Kracov, Partner, ARNOLD AND PORTERPanelists:Petra Jaeger, Clinical Operations Group Head Quality & Training, NOVARTIS PHARMACEUTICALS GMBHLisa Kaufman, Director, Clinical Operations, MERSANA THERAPEUTICSLynn Sutton, Vice President, Clinical Services, ALLOS THERAPEUTICS• Regulatory and FDA backdrop on clinical trials• Overcoming ethical and compliance restrictions with supplying

tools to and communicating with patients ◆ What’s allowed? ◆ Successfully approaching your counsel/regulatory team• Confidentiality issues with trial sites and online communities• Comparison of regulatory considerations for doing research in

other countries

4:30 CONfERENCECONCLUDES

DaY TWo • Wednesday, March 2, 2011

To RegisTeR Call 866-207-6528 oR visiT us aT www.exlpharma.com/Kolsummit

Media Partners

Do you have a question about the event? Would you like to get involved as a speaker or discussion leader at our 3rd Patient Engagement Summit: New Technologies for Engaging Patients in Clinical Trials? Please email Conference Director, Dave Hoffman at dhoffman@exlpharma.com

Five Ways to RegisterFax: 888-221-6750Mail: Exl Events, inc. 555 8th ave, Ste 310 New York, NY 10018PhoNE: 866-207-6528oNliNE: www.exlpharma.comEMail: register@exlpharma.com

Registration Fees for attending Exl Pharma’s 2nd Patient Engagement Conference:EARLY BIRD PRICING

Register by Friday, January 14, 2011to Take Advantage of Early-Bird Pricing:Conference + Workshop $1995Conference Only $1695

STANDARD PRICINGRegister After Friday, January 14, 2011: Conference + Workshop $2195Conference Only $1895

ONSITE PRICINGConference + Workshop $2295Conference Only $1995

Group Discount Program: Discounts cannot be combined; Early Bird Rates do not apply

Save 25% per person when Registering Four For every three simultaneous registrations from your company, you will receive a fourth complimentary registration to the program (must register 4 at one time). This is a savings of 25% per person.

Save 15% per person when Registering Three Can only send three? You can still save 15% off of every registration. To find out more on how you can take advantage of these group discounts, please call 866-207-6528.

Make checks payable to ExL Events, Inc. and write code P907 on your check. You may also use Visa, MasterCard, Discover or American Express. Payments must be received in full prior to the commencement of the conference.

Cancellations: If you need to cancel your registration for an upcoming ExL conference, please note the following policies derived from the Start Date of the event:

Four weeks or more: A full refund (minus a $95 processing fee), or a voucher to another ExL event valid for two years from the voucher issue date.

Four weeks or Less: A voucher to another ExL event valid for two years from the voucher issue date.

To receive a refund or voucher, please fax your request to 888-221-6750.

Please Note: Conference registrations may be transferred to other colleagues in the event you are unable to attend. There will be an administrative charge of $300 to substitute, exchange and/or replace attendance badges with a colleague occurring within five business days of any ExL conference.

Please notify ExL Pharma, info@exlpharma.com, prior to the event with the name and contact information of the replacement attendee.

Please Note: Speakers and agenda are subject to change without notice. In the event of a speaker cancellation, every effort to find a suitable replacement will be made.

*The opinions of this faculty do not necessarily reflect those of the companies they represent nor ExL Events, Inc.*

Registration FormMail: ExL Events, Inc. Phone: 866-207-6528 555 8th Ave, Ste 310 Fax: 888-221-6750 New York, NY 10018 Email: register@exlpharma.com

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TO REGISTER: Call 866-207-6528 or visit us at ww

w.exlpharm

a.com

Conference Chair:Craig Lipset, Senior Director (Clinical Research) and Venture Partner (Pfizer Venture Investm

ents), PFIZER

2nd Patient Engagement Summit: New Technologies for Engaging Patients in Clinical TrialsIm

plementing Cutting Edge Com

munication

Technology to Facilitate Recruitment,

Compliance, and Retention in Clinical Trials

Proudly Presents:

MARCH 1-2, 2011

CROWN

E PLAZA PH

ILADELPHIA DOW

NTOWN

Our Esteemed Speaker Faculty:Craig Lipset Senior Director (Clinical Research) and Venture Partner (Pfizer Venture Investm

ents), PFIZERDavid Leventhal Director, Healthcare Inform

atics, PFIZERGretchen Goller Patient Recruitm

ent/Compliance

Strategist-Operations, SANOFI-

AVENTIS

Karen Brooks Director, Clinical Projects, SAN

OFI-AVEN

TISLinda Deal Director, Patient Reported Outcom

es, JOHN

SON & JOHN

SONLynn Sutton Vice President, Clinical Services, ALLOS THERAPEUTICSM

ats Sundgren Principal Scientist, Global Clinical Developm

ent, ASTRAZENECA

Melanie Goodw

in M

anager, Global Trial Optimization,

MERCK

Miguel Orri

Senior Director, PFIZERJoseph Kim

Director of Clinical Operations, SHIRE PHARM

ACEUTICALSLisa Kaufm

an Director, Clinical Operations, M

ERSANA THERAPEUTICS

Petra Jaeger Clinical Operations Group Head Quality & Training, N

OVARTIS PHARM

ACEUTICALS GMBH

TO REGISTER: Call 866-207-6528 or visit us at ww

w.exlpharm

a.com

Featured Presentations:PFIZER CASE STU

DY: ONLIN

E CLINICAL TRIAL

Early Look at Pfizer’s Unprecedented Study—the First Clinical Trial to Exclusively Use Online Recruitm

ent, a Web-Based Inform

ed Consent Process, and Virtual Follow

-Up for Patient Engagement

Miguel Orri, Senior Director, Clinical Sciences (Prim

ary Care Business Unit), PFIZER

CASE STUDY: ON

LINE COM

MU

NITIES

Creating and Nurturing Patient Driven Online Com

munities to Validate Interest

in Study ParticipationLynn Sutton, Vice President, Clinical Services, ALLOS THERAPEUTICS

MERCK’S “CENTER OF EXCELLEN

CE” ON GAININ

G INTERNAL BUY-IN:

Preparing the Internal Team for a Study Using Tools of the 2.0 Age so Your Trial’s

Clinical Data is Processed in a Timely M

annerM

elanie Goodwin, M

anager, Global Trial Optimization, M

ERCK

ePRO CASE STUDY: DEVELOPIN

G AND VALIDATIN

G A DAILY ELECTRONIC

ENDOM

ETRIOSIS PAIN AND BLEEDIN

G DIARY (EPBD)Advances in Electronic Patient Reported Outcom

es (ePRO) that Increase Accuracy and Im

prove Compliance in Clinical Trials

Linda Deal, Director, Patient Reported Outcomes, JOHN

SON & JOHN

SON

Utilizing Electronic Health Records To More Efficiently Identify Potential Trial ParticipantsA PAN EU

ROPEAN CASE STUDY: The Benefits of the Innovative M

edicine Initiative’s EHR4CR Project, w

hich Shares Information Betw

een 32 Partners—Including 10 Pharm

aceutical Companies—Across M

ultiple Nations

Mats Sundgren, Principal Scientist, Global Clinical Developm

ent, ASTRAZENECA

PACeR CASE STUDY: The Advantages of New York State’s EHR Clinical Trials Netw

orkDavid Leventhal, Director, Healthcare Inform

atics, PFIZERSponsored by: