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The University of Western AustraliaSchool of Psychiatry and Clinical Neurosciences

Neuropsychiatric Epidemiology Research Neuropsychiatric Epidemiology Research Unit Unit NERUNERU

Annual Report 2008Annual Report 2008

Neuropsychiatric Epidemiology Research Unit ANNUAL REPORT 20082

Neuropsychiatric Epidemiology Research Unit ANNUAL REPORT 2008 3

CONTENTS

CONTENTS 3

OVERVIEW 7

STRUCTURE 2008 8

STAFF 2008 9

AWARDS AND PRIZES 2008 9

RESEARCH PROGRAMS 10

METHODOLOGIES 15

INSTRUMENT DEVELOPMENT 17

RESEARCH FUNDING RECEIVED/COMMITTED 2008 ONWARDS ($) 20

PUBLICATIONS 2008 21

CONFERENCE PRESENTATIONS 2008 23

RESEARCH COLLABORATIONS AND ACTIVITIES 2008 24

VISITORS 2008: INTERNATIONAL AND NATIONAL 27

VISITORS 2008: TALKS AND RELATED 30

STAFF: PROFILES 31

STAFF: FORMAL OFFICES HELD 2008 28

STAFF: CONFERENCE ORGANISING COMMITTEES 2008 28

STAFF: OTHER COMMITTEE MEMBERSHIP 2008 29

Appendix 1: Research Funding 1995-2007 ($) 36

Appendix 2. Selected publications 1995-2007 (Epidemiology) 38

Contact details 43


NERU.A mountain in Himavā

All birds settling there become golden


OVERVIEW

The Neuropsychiatric Epidemiology Research Unit was established as a unit within the School of Psychiatry and Clinical Neurosciences at the University of Western Australia early in 2008. This formalised a de facto structure dating back to the early 1990s when Professor Assen Jablensky arrived from overseas to take the inaugural University of Western Australia Chair of Psychiatry at Royal Perth Hospital. Professor Jablensky was already renowned as a world expert in the epidemiology of schizophrenia (playing a lead role in the influential WHO 10-Country Study) as well as in the classification of psychiatric illness. In 1994, he was awarded his first Australian grant to study the epidemiology of schizophrenia, using the Western Australia psychiatric case register in an ecological study examining the risk of schizophrenia following in utero exposure to influenza epidemics. Other grants and contracts followed, allowing him to develop his two streams of interest: the genetics of schizophrenia and the epidemiology of schizophrenia. The clinical and genetic arm of research was realised through a stream of National competitive grants at the Centre for Clinical Research in Neuropsychiatry at Graylands Hospital that Professor Jablensky established. Other grants supported the epidemiological work at the Royal Perth Hospital location. This included a US Stanley Foundation grant in 1996 to examine reproductive pathology in mothers with psychoses where the focus was on the interaction between environmental and genetic risk factors for schizophrenia. At the same time, a large Commonwealth contract to lead the first National survey on the prevalence and profile of psychosis in Australia, the Low Prevalence (Psychotic) Disorders Study. Most of the current staff in the Unit have a long history of working in schizophrenia epidemiology with Professor Jablensky including Anna Waterreus (since 1994), Vera Morgan (since 1995), Giulietta Valuri (since 1997) and Jenny Griffith (in 1997-98, then again since 2004)

In 2008, the Neuropsychiatric Epidemiology Research Unit remains concerned primarily with research into the epidemiology of schizophrenia and other neuropsychiatric disorders including their genetic and environmental risk factors, course and outcome. The Unit has a long history of success in attracting national competitive and international funding to undertake its core program of research including the continuing study of obstetric pathology in women with severe mental illness; the association between genetic risks and obstetric complications in the aetiology of schizophrenia; developmental trajectories for the children of parents with severe mental illness; criminal offending and psychosis; intellectual disability and co-occurring psychiatric illness. Most studies have been designed to allow some assessment of the specificity of findings to schizophrenia compared to other psychotic disorders. Unit staff have also been very successful in attracting government contracts. Currently, they are working closely with the Commonwealth Department of Health and Ageing to undertake a second national survey of psychosis and have also entered into fruitful collaboration with the Western Australian Department of Health. The Head of Unit has a formal role as an operational epidemiologist within North Metropolitan Mental Health Services in Western Australia, while a research collaboration has been established with the Department of Health to investigate factors affecting inpatient demand in this State. In recent years, the Neuropsychiatric Epidemiology Research Unit and the Centre for Clinical Research in Neuropsychiatry have explored opportunities for working together in order to realise Professor Jablensky’s original vision of bringing together epidemiological and clinical streams of research to further our understanding of the aetiology of schizophrenia.

Much of the work of the unit is undertaken using the Western Australian psychiatric case register and linking this to the extensive network of other electronic State registers of morbidity and mortality. Linked register data are supplemented with data from clinical casenotes in a number of studies. The Unit is also experienced in the use of survey methodologies, especially the design and coordination of multisite epidemiological


surveys. The Unit has developed and refined a number of instruments, described in the report.

The Neuropsychiatric Epidemiology Research Unit is made up of committed researchers from a variety of disciplines. The breadth of scientific and clinical expertise, professional skills and human experience and engagement that they bring to the Unit is its greatest asset.


STRUCTURE 2008

Neuropsychiatric Epidemiology Research Unit

Figure 1.Organisational structure, Neuropsychiatric Epidemiology Research Unit, 2008


Head of School

A Janca

10

Head of Neuropsychiatric Epidemiology Research UnitV Morgan

Senior scientific consultant / Director: Centre for Clinical

Research in NeuropsychiatryA Jablensky

School support:

Administrative: S GeeIT: D Brown

Clinicalresearch

A WaterreusJ Griffith

C Simpson

Statistics and database

management

M CroftG ValuriR AgungS Shah

Instrument development and training

A WaterreusJ GriffithJ Dean

STAFF 2008

Dr Vera Morgan Research Associate Professor

Unit Head / Operational Epidemiologist

Prof Assen Jablensky Winthrop Professor Senior Scientific Consultant / Director: Centre for Clinical Research in Neuropsychiatry

Dr Maxine Croft Research Assistant Professor

Epidemiologist / Biologist

Mr John Dean Research Nurse Consultant Research Nurse Consultant

Ms Jenny Griffith Senior Research Officer Mental Health Clinical Research Nurse / WA Site Coordinator for National SHIP Survey

Dr Agung Riono Research Assistant Professor

Epidemiologist

Dr Sonal Shah Research Associate Medical and Vital Statistics

Ms Cate Simpson, OAM Research Officer Mental Health Clinical Researcher Nurse

Ms Giulietta Valuri Research Assistant Professor

Epidemiologist / Criminologist

Ms Anna Waterreus Research Assistant Professor

National Coordinator for SHIP Survey

AWARDS AND PRIZES 2008

Jenny Griffith 2008 University of Western Australia Staff Development Award

Agung Riono Lions Institute Dr John Hoffman Scholarship (2007-2008)

Giulietta Valuri 2008 Schizophrenia International Research Society Travel Award


RESEARCH PROGRAMS

Pathways to schizophrenia from conception to disease: The children of parents with severe mental illness

This study is designed to untangle genetic and environmental contributions to the risk for schizophrenia and other adverse outcomes in the children of mothers with schizophrenia and other severe mental illness using Western Australian whole-of-population health databases.

Phase 1. The first phase of this program of work was concerned with reproductive pathology in mothers with schizophrenia, bipolar disorder and unipolar major depression, and early outcomes for their offspring. Records for 79,599 women on the Western Australian psychiatric case register were cross-linked to 308,022 birth records on the midwives database. Women with psychosis who had given birth in Western Australia between 1980 and 1992 were identified. Comparison mothers were randomly selected from mothers with no record of psychiatric illness. Fathers were identified using birth registrations. There were 3174 high risk children born 1980-1992 to mothers with schizophrenia, bipolar disorder or unipolar depression and 3129 comparison children born to unaffected mothers. Full psychiatric histories for mothers, fathers and children were extracted, and data collected on obstetric complications and other childhood morbidities. The study aims were to: (i) determine the frequency and distribution of obstetric complications in women with schizophrenia compared to a non-psychiatric comparison group of mothers; (ii) explore the spectrum of outcomes for the children born to women with schizophrenia; (iii) assess specificity of findings to maternal schizophrenia compared to maternal bipolar disorder and unipolar major depression; and (iv) examine the relationship between familial psychiatric status, obstetric complications and mental health outcomes for children (work in progress). This study found that women with schizophrenia, bipolar disorder, and unipolar depression experience an increased overall incidence of obstetric complications, relative to the nonpsychiatric comparison group. A major factor contributing to the increased risk of obstetric complications in women with schizophrenia and, to a lesser degree, in women with affective disorders appears to be the clustering of adverse maternal characteristics. Moreover, it is likely that behavioural disorganisation and environmental exposures including poor nutrition and substance use may play an important role in the excess of obstetric complications in births that occur after the onset of psychosis only. This is supported by the finding that the incidence of adverse outcomes in all three diagnostic groups was significantly increased only in pregnancies occurring after the onset of psychiatric illness. Some obstetric complications showed no pre-onset / post-onset differences. These occurred only in women with schizophrenia, and included placentation abnormalities, low birthweight, minor physical anomalies and cardiovascular birth defects. This constancy in rates suggests a diagnosis-specific pre-existing susceptibility that may involve both genetic and environmental components.

Phase 2.The second phase of this program of work develops our earlier research. In this current program of work, we have extended the study cohort to 249,119 mothers with 472,722 children born 1980-2001, including 14,418 high-risk children born to women with psychoses. Fathers have been identified and their mental health status ascertained. All children have been followed up on the health registers (psychiatric, midwives, hospital morbidity, mortality, birth defects, intellectual


disability, cerebral palsy, cancer); 19,762 have had an in- or outpatient contact with mental health services including 1314 with a recorded diagnosis of psychosis (303 with schizophrenia). In addition, detailed diagnostic and developmental data are being extracted manually from the clinical case notes of children with a diagnosis of psychosis. Data analysis models will use: generalised estimating equations for binary outcomes to obtain population averaged estimates for the influence of environmental and genetic risk factors and their interaction; and structural equation models to assess likely causal and non-causal pathways. The specificity of findings to schizophrenia will be assessed. Follow-up of this cohort of children will increase substantially our capacity to provide definitive answers to unresolved questions about the relative contributions of reproductive pathology and genetic liability to the incidence of major mental disorders. The study will also provide a unique evidence base for better informed preventative interventions and management strategies including risk reduction through targeted antenatal and postnatal interventions.

In 2008: Work continued on analysis and paper preparation based on data from the

Phase 1 program of research (N=6303 children) focusing on neuropsychiatric outcomes in the children.

For the Phase 2 program of work, the design and construction of data model was completed, constructs were developed and scales were refined (see Methodologies on page 15 and Instrument Development on page 17). Data cleaning and manipulation was ongoing.

Findings from Phase 1 and the design and methodologies employed in Phase 2 were presented at national and international fora.


Schizophrenia prevalence: National Survey of High Impact Psychosis (SHIP)

The Survey of High Impact Psychosis (SHIP) is the planned second national population-based survey of the prevalence and profile of psychosis in Australia. It will be conducted in catchments across five States: QLD, NSW, SA, VIC and WA. It is the follow-up to the first national survey of psychosis in 1997-1998: Australian National Survey of Mental Health and Wellbeing. Study ofLow Prevalence (Psychotic) Disorders(LPDS). The premise underlying SHIP is that the social milieu in which people with psychosis find themselves plays a critical role in their functioning and recovery, and that the breakdown in the interaction between a person and their environment is a useful target for intervention in the management of psychosis. The mission of SHIP is to identify those factors associated with good outcome in psychosis that are amenable to change and critical to recovery with a particular focus on the assessment of measures related to social participation, living circumstances, and physical well-being. Unique to the survey will be the identification of facets of role support associated with positive social integration and the evaluation of domains of cognitive function in order to determine appropriate targets for rehabilitation and skills development. The convenor of the SHIP Technical Advisory Committee, the national Survey Coordinator and the Chief Scientific Advisor to the survey are from the Neuropsychiatric Epidemiology Research Unit.

In 2008: Phase 1 work on instrument development and survey design was completed. Phase 2 funding to bring the survey close to enumeration-readiness was

secured from the Commonwealth. There were several meetings of the national Technical Advisory Committee. Consultation commenced with services in the Western Australian catchment.


Study of High Users of Psychiatric Inpatient Services

This project has two components. The first component is to establish a database of the health history of people admitted to a psychiatric inpatient facility during the years 1990 to 2006. The second is a specific study of patterns of use of inpatient psychiatric facilities using the constructed database. This work is being undertaken with the Western Australian Mental Health Policy Research Centre in the Western Australian Department of Health.

In 2008: An application was made for linked data (psychiatric, hospital morbidity,

mortality and emergency department)

Criminal offending, schizophrenia and other psychiatric illness

In the Western Australian study, Criminal offending and psychosis, 219,052 individuals on the psychiatric case register were linked to 388,370 individuals on the criminal arrests database. The total number of cross-linked individuals was 52,091, comprising 23.8% of persons on the psychiatric register and 13.4% of persons on the arrests database. Prevalence and profile of offending in persons with schizophrenia was compared with that for persons with other psychiatric disorders and those with no psychiatric history. Analysis of the total study population indicates differential contact with the justice system by diagnostic group. Overall 48.5% of individuals with drug and/or alcohol-related diagnoses and 39.1% of individuals with personality disorders had contact with the justice system, compared to 32.5% of those with schizophrenia. The majority of offenders with a psychiatric history had been arrested prior to contact with psychiatric services, and survival analysis demonstrated that first contact with psychiatric services was most likely to occur within the first year of arrest, highlighting the role of police as potential gatekeepers for the mental health system. Using subsample data, compared to persons with no psychiatric history, persons with a psychiatric illness were more likely to offend alone, to have no relationship with their victim, and to offend outside their region of residence. Additional analysis of area-level data for disadvantage, inequality, ethnic homogeneity, residential mobility and urbanicity indicated that the same neighbourhood-level variables that are risk factors for offending in the general population are also risk factors for individuals with schizophrenia. However, compared to the general population, individuals with schizophrenia are more likely to be exposed to social disadvantage and other neighbourhood-level risk factors that predict offending in non-psychotic populations. Therefore it is possible that a large component of the risk of offending in persons with schizophrenia stems from their living circumstances rather than as a direct consequence of their mental health status. In sum, from a psychiatric perspective, there are indications that early offending and/or a history of substance abuse may be early manifestations of schizophrenic illness confounding the determination of first onset of psychosis. From a criminological perspective, shared community factors related to social disorganisation may influence the timing and nature of offending, substance misuse and the expression of schizophrenia in those people with vulnerabilities.

In 2008: The first draft of the main paper from this study was completed. This identified

a number of changes that needed to be made to the study database; work on the required changes has commenced.

Analyses for the sub-project on social disorganisation and offending patterns in schizophrenia compared to the general population were completed. The results were presented internationally and were published in Trends and Issues in Crime and Criminal Justice.


Intellectual disability and co-occurring schizophrenia and other psychiatric illness

The epidemiology of intellectual disability co-occurring with schizophrenia and other psychiatric illness is poorly understood. The separation of mental health from intellectual disability services has led to a serious underestimation of the prevalence of dual diagnosis, with clinicians ill- equipped to treat affected individuals. Yet one of the more consistent findings in the literature is an elevated lifetime risk of schizophrenia among individuals with intellectual disability. Kraepelin estimated that the basis of some 3.5% of cases of dementia praecox is intellectual disability resulting in an early onset form of psychosis which he called “Pfropfschizophrenie” (literally “engrafted schizophrenia”). Current estimates still put the risk of schizophrenia in intellectually disabled populations at around 3%, compared to a lifetime risk of around 1% in the general population. However the evidence base for this estimate is limited, with methodological and nosological issues affecting the reliability of estimates. In this study, two Statewide registers, the intellectual disability and the psychiatric case registers, were cross-linked in order to estimate the prevalence of dual diagnosis and describe its clinical profile, with a total study pupoulation of 245,749. Two birth cohorts (1950-64 and 1965-79) were identified for intensive analysis. Overall, 31.7% of persons with an intellectual disability had a psychiatric disorder; 1.8% of persons with a psychiatric illness had an intellectual disability. Schizophrenia, but not bipolar disorder and unipolar depression, were greatly over-represented among cases of dual diagnosis: depending on birth cohort, 3.7-5.2% of persons with an intellectual disability had a schizophrenia-spectrum disorder. Pervasive developmental disorder was more common among dual diagnosis cases than among cases of intellectual disability alone. Down syndrome was much less prevalent among dual diagnosis cases despite being the most predominant cause of intellectual disability. Dual diagnosis cases had a different aetiological basis compared to cases of intellectual disablement alone, and presented a more serious clinical profile compared to cases of psychiatric morbidity alone. The facility to combine records across two separate administrative jurisdictions in this study is having a marked impact on our understanding of the epidemiology of dual diagnosis, its clinical manifestations and aetiological implications. In particular, our results are suggestive of a common pathogenesis in intellectual disability co-occurring with schizophrenia.

In 2008: A PhD based on this study was awarded with distinction. The findings of the study were published in British Journal of Psychiatry.

Schizophrenia incidence: Western Australia and Verona

This study will enable us to estimate the annual treated incidence of schizophrenia in Verona and Western Australia over a period of two decades, and to compare these rates between the two sites with a view to: getting an estimate of annual incidence in South Verona and Western Australia; assessing whether the incidence rate is changing over time and whether the rate is stable across different geographic regions; calculating the lag between first contact for any reason with in- or out-patient mental health services and first recorded diagnosis of a psychotic disorder; mapping changes in the profile of persons on first presentation to services with a psychotic disorder over time; examine whether a higher level of urbanization is associated with an increased risk of developing schizophrenia for both women and men, after adjustment for individual demographic and socioeconomic characteristics. The study design is a 24-year retrospective epidemiological survey. It will use data on the South Verona Psychiatric Case Register and the Western Australia Mental Health Information System in order to determine the annual rates of new cases of schizophrenia in Verona and Western Australia over the study period.


In 2008: Study collaborators from Verona and Perth met to revised the protocol to cover

more recent years of first contact with services and to incorporate a better range of social indicators that are available on both psychiatric case registers.


METHODOLOGIES

Research utilising record linkage across registers and through generations

The Neuropsychiatric Epidemiology Research Unit has extensive experience in the use of multigenerational cross-linked data from the Western Australian psychiatric case register, State health (e.g. morbidity, birth defects, midwives, mortality) and other registers (e.g. criminal; intellectual disability) to study prevalence, incidence, aetiology and risk factors. See Figure 2 below for an example based on the study of Pathways to Schizophrenia study. Unit researchers are expert at designing and developing sophisticated hierarchical data models for linking, interrogating and analysing data across registers and through generations. Operationalising and validating key constructs using register data (e.g. diagnosis; neonatal encephalopathy; socioeconomic status; adversity) is a priority.

In 2008: The design and construction of the data model was completed. A construct for neonatal encephalopathy was developed and is currently being

validated. A protocol was developed for mapping graphically children’s developmental

trajectories and milestones from register data.

Figure 2. Model of record linkage for the Pathways to Schizophrenia study. The database includes 249,119 mothers and 472,722 children (born 1980-

2001).


Clinical casenotes review

Register data are supplemented by psychiatric data extracted from clinical casenotes by experienced mental health nursing professionals. Several instruments have been developed for this purpose including an adaptation of the Diagnostic Interview for Psychosis for use with children’s casenote data, and the Children’s Checklist that was developed internally specifically for the collection of data for children on substance misuse, psychotropic medication use, behavioural problems, neurocognitive data and psychopathology not recorded in the Diagnostic Interview for Psychosis.

In 2008: A protocol was established for standardising the extraction of life histories

from clinical casenotes and for presenting them in summary form. A protocol was established for the independent review of register-based

diagnoses for children. Two expert diagnosticians began reviewing cases. This work is ongoing.

Survey-based research

The Neuropsychiatric Epidemiology Research Unit is experienced in the design, instrument development and coordination of large national multisite surveys including, in 1997-98, the first national survey the Study of Low Prevalence (Psychotic) Disorders and the planned national Survey of High Impact Psychosis (SHIP) 2010. See Figure 3 below for the methodology for both surveys.

Figure 3. Two-phase methodology employed in the first national survey, LPDS 1997-98, and the planned national Survey of High Impact Psychosis 2010.


INSTRUMENT DEVELOPMENT

Diagnostic Interview for Psychosis (full versions: LPDS and SHIP)

The Diagnostic Interview for Psychoses (DIP) is a semi-structured interview for psychoses for use in epidemiological and clinical settings. It is designed to provide a diagnosis, as well as to assess symptom profiles (present state, past year and lifetime), social functioning, disablement, and service utilisation. The DIP was developed specifically for the National Mental Health Survey – Low Prevalence (Psychotic) Disorders Study (LPDS), conducted in Australia from 1997 to 1998. The original version of this clinical interview includes three modules: (i) Demography and Social Functioning Module (DIP-DSFM); (ii) Diagnostic Module (DIP-DM); and (iii) Service Utilisation Module (DIP-SUM). The Diagnostic Module is described in a separate section below.

In 2008: In preparation for the national Survey of High Impact Psychosis (SHIP), all

modules of the DIP, other than the Diagnostic Module, underwent substantial redevelopment. The revised Demography and Social Functioning Module covers: basic demographic information; education; employment; housing; finances; activities of daily living; child care; caring; socialising; self harm; victimisation & offending; satisfaction with life. The revised Service Utilisation Module covers: inpatient treatment; emergency/casualty treatment; outpatient treatment; public community mental health; community rehabilitation and day therapy; general practice service; non government agencies; medication use; mental health care & unmet need. Other psychopathology and cognition, drug, alcohol and smoking, and physical health assessment modules have been added. This work is still in progress.

Diagnostic Interview for Psychosis – Diagnostic module (DIP-DM 4.0.11)

The Diagnostic Module of the Diagnostic Interview for Psychoses (DIP-DM) is a semi-structured interview consisting of the 97 items of the Operational Criteria For Psychosis (OPCRIT). The DIP_DM uses probes and differential definitions derived and adapted from the WHO Schedules for Clinical Assessment in Neuropsychiatry (SCAN). Items cover: depression, mania, hallucinations, subjective thought disorder, delusions, behaviour and affect. The DIP-DM is designed for administration by mental health professionals and training is required. User-friendly Windows-based software is available that allows the data entry of information from the diagnostic module into a database, which then generates diagnoses using the underlying Operational Criteria For Psychosis (OPCRIT) algorithm. The development, reliability and applications of the DIP have been published. The DIP-DM is being used in New Zealand, UK, US and, in translation, in Indonesian, Italy, Spain, France and Bulgaria.

In 2008: DIP-DM manual was revised (DIP-DM 4.0.11) to include DSM-IV as well as ICD-

10, DSM-IIIR, RDC and other diagnostic criteria. A comprehensive drug and alcohol section was included. DIP-DM prompts were modified to include instructions for its use solely with

good-quality casenotes. Work began on Norwegian and Greek translations of the DIP-DM.


Psychosis Screen (revised)

The Psychosis Screen was also developed specifically for the LPDS. It is a brief instrument (one page) covering 8 items and takes 1-2 minutes to complete. There are two versions: a Key Worker Form and a Patient Form. A revised version of the Psychosis Screen will be used in the Survey of High Impact Psychosis (SHIP).

In 2008: The Psychosis Screen was revised to remove redundancies, to streamline the

flow of questions and to improve its psychometric properties.

McNeil-Sjöström Scale for Obstetric Complications

The McNeil-Sjöström Scale operationalises the scoring of hundreds of obstetric complications and their treatment, including the range of potential complications from common to rare. The scale is underpinned by both biological and aetiological considerations and is designed to take a better account of the amount, timing and severity of obstetric complications. It produces separate summated scores indicating the number of complications of a particular severity level for each of three time periods (pregnancy, labour and delivery, and the neonatal period) as well as producing an overall score. In 1996, a PhD student within the Unit, Dr Li-Anne Yellachich, wrote and validated a computer algorithm to automate the scoring of obstetric complications recorded on the electronic Midwives register. The original algorithm covered 6303 birth records. Our project data now include almost 500,000 birth records necessitating changes to the algorithm and at times, to the underlying scale elements.

In 2008: Revisions to the scale to incorporate conditions not covered by the original

listing of disorders and conditions were continuing. Revision of the original computer algorithm to include the many new ICD codes

in 500,000 birth records was in progress.

Measures of longitudinal maternal morbidity

Current methods of calculating estimates of risk for adverse birth outcomes such as the McNeil-Sjöström Scale for Obstetric Complications generally use a birth as the outcome measured and assume that each birth is a random event independent of prior events for the mother. Such methods of calculation using cross-sectional data are flawed by the lack of accurate longitudinal, population data on outcomes based on the mother and her reproductive history as the unit of measurement. In previous research by Dr Maxine Croft on risk factors for two birth outcomes (sudden infant death syndrome and birth defects), the use of cross-sectional maternal health data was compared with the use of longitudinal maternal health data. New risk factors were identified using longitudinal maternal health data and, for some known risk factors, significantly different odds ratios resulted when compared with cross-sectional data. Work is in progress to determine whether the McNeil-Sjöström Scale algorithm should use all available longitudinal maternal health data or whether the mother's current birth record provides the best estimate of the mother's health.

In 2008: Dr Maxine Croft undertook further investigations through her study of mothers

of singletons compared to mothers of twins. This provided an ideal opportunity for assessing whether there were biases in the recording of maternal health and determining whether cross-sectional or longitudinal data gave the best estimate of maternal health.


Children’s Checklist

Children’s Checklist is an instrument developed within the Unit specifically for the collection of children’s data on substance misuse, psychotropic medication use, behavioural problems, neurocognitive data and psychopathology not recorded in the Diagnostic Interview for Psychosis.

In 2008: No revisions were required. Clinical and reliability data collection using the

instrument were ongoing.

Instrument validity and reliability

Testing the psychomteric properties of instruments used and/or developed including their validity and inter-rater reliability where appropriate, and assessing the reliability and validity of key constructs is an ongoing priority for the Unit.


RESEARCH FUNDING RECEIVED/COMMITTED 2008 ONWARDS ($)

* Note: As this is the first annual report for the Unit, archival material on the Unit’s income from research grants and contracts prior to 2008 is provided in Appendix 1.

Funding Source

Investigators

Study Title 2008 2009 2010 2011

NH&MRC Jablensky AKalaydjieva LSegal MBadcock JWiltshire SPrice GMorgan V

Memory synaptic plasticity and gene networks in schizophrenia

113,500

454,250

242,750

272,750

March of Dimes Research Foundation

Jablensky AMorgan VBower CZubrick SCroft M

A population-based study of obstetric, developmental and neuropsychiatric outcomes in the offspring of women with severe mental disorders

93,500 93,500

NH&MRC Jablensky AMorgan V

Children of parents with mental illness: a population-based study

294,000

131,125

NH&MRC Jablensky AKalaydjieva LBadcock JKendler KMorgan, VRiley B

Genetics of cognitive impairment in schizophrenia

235,000

Commonwealth Dept of Health and Ageing

Morgan VJablensky A

National survey of high impact psychosis (SHIP): Phase 2

606,903


Morgan VJablensky A

Scoping a national survey of high impact psychosis (SHIP): Phase 1

78,006


PUBLICATIONS 2008

* Note: As this is the first annual report for the Unit, archival material on the Unit’s publications prior to 2008 is provided in Appendix 2.

Journal ArticlesAbel K, Webb R and Morgan V. Taking the Spotlight off Schizophrenia. eLetter. British Journal of Psychiatry http://bjp.rcpsych.org/cgi/eletters/193/4/311 (10 Dec 2008) [IF 2007: 5.446]Jablensky, A.V. and Sartorius, N. What did the WHO Studies really find? Schizophrenia Bulletin, 2008 34(2):253-5. [IF 2007: 5843]Hauck, Y., Rock, D.J.T., Jackiewicz, T. and Jablensky, A.V. Healthy babies for mothers with serious mental illness: a case management framework for mental health clinicians. International Journal of Mental Health Nursing, 17(6), 383-391.[Not in Thomson ISI]Morgan V, Leonard H, Bourke J, Jablensky A. Intellectual disability co-occurring with schizophrenia and other psychiatric illness: a population-based study. British Journal of Psychiatry, 2008 193, 364–372 [IF 2007: 5.446]Morgan F, Morgan V, Clare J, Valuri G, Woodman R, Ferrante A, Castle D, Jablensky A. Schizophrenia and offending: area of residence and the impact of social disorganisation and urbanicity. Trends and Issues in Crime and Criminal Justice 2008, 365. [Not in Thomson ISI]Morgan V, Castle D, Jablensky A. Do women express and experience psychosis differently from men? Epidemiological evidence from the Australian National Study of Low Prevalence (Psychotic) Disorders. Australian and New Zealand Journal of Psychiatry, 2008, 42, 74-82 [IF 2007: 2.573]Davis SR, Shah SM, McKenzie DP, Kulkarni J, Davison SL, Bell RJ. Dehydroepiandrosterone sulfate levels are associated with more favourable

cognitive function in women. Journal of Clinical Endocrinology & Metabolism, 2008: 93: 801-808 [IF 2007: 5.493]Swanson PB, Kane RT, Pearsall-Jones JG, Swanson CF, Croft ML. How couples cope with the death of a twin or higher order multiple. Twin Research and Human Genetics (accepted July 2008) [IF 2007: 1.525]

Books and ChaptersFarmer, A.E. and Jablensky, A.V. Current approaches to classification. In R Murray, P Hill, P McGuffin (ed) The Essentials of Postgraduate Psychiatry, 4th ed, Cambridge University PressCastle D and Morgan V. Epidemiology of schizophrenia. in Mueser, K and Jeste, D (eds.) The Clinical Handbook of Schizophrenia, Guilford Press, New York (2008)

ReportsHauck Y, Rock D, Jackiewicz T & Jablensky A (2008) Healthy Babies for Mothers with Serious Mental Illness: A case management framework for mental health clinicians - Clinicians’ Manual. North Metropolitan Area Health Service (Mental Health), WA Department of HealthHauck Y, Rock D, Jackiewicz T & Jablensky A (2008) Healthy Babies for Mothers with Serious Mental Illness: A case management framework for mental health clinicians - Framework Overview. North Metropolitan Area Health Service (Mental Health), WA Department of Health.

Published abstracts


Croft ML, Griffith J, Morgan V, Valuri G, Jablensky AV. High risk children of Morgan V, Zubrick S, Bower C, Croft M,

Valuri G, Jablensky A Determinants of


CONFERENCE PRESENTATIONS 2008

Oral presentationsCroft ML, Morgan V, Valuri G, Bower J, Zubrick S, Jablensky A. Obstetric risk factors for schizophrenia: identifying neurological damage and/or hypoxia in infants using population databases. Australasian Schizophrenia Conference, Lorne, 23-24 Oct 2008Morgan F / Morgan V (co-presenters), Clare J, Valuri G, Ferrante A, Jablensky A. Schizophrenia and offending - the impact of social disorganization and routine activities. 16th Environmental Criminology and Crime Analysis (ECCA) Conference, Izmir, Turkey, March 15-19, 2008Morgan V. National Study of High Impact Psychosis (SHIP). Australasian Schizophrenia Conference, Lorne, 23-24 Oct 2008 (Plenary)Morgan V, Zubrick S, Bower C, Croft M, Valuri G, Griffith J, Jablensky, A Determinants of adverse psychiatric outcomes for high risk children of mothers with schizophrenia and other psychoses: The role of environmental and familial risk factors. Australasian Schizophrenia Conference, Lorne, 23-24 Oct 2008Morgan V, Zubrick S, Bower C, Croft M, Valuri G, Jablensky, A. Determinants of elevated risk of intellectual disability in children of mothers with psychoses. Australasian Society of Psychiatric Research Annual Meeting, Newcastle, 2-5 Dec 2008

Schizophrenia International Research Society Annual Scientific Meeting, Venice 2008

Poster presentationsCroft ML, Griffith J, Morgan V, Valuri G, Jablensky AV. High risk children of women with schizophrenia and other mental illness: instruments for assessing risks and identifying outcomes. Schizophrenia International Research Society Annual Meeting, Venice, 21-25 June 2008Laugharne J and Waterreus A Screening for the metabolic syndrome in psychiatric patients: evidence of current practice at a major psychiatric teaching hospital in Western Australia. Australasian Physical And Mental Health Interface Conference Melbourne, 15-16 August 2008Morgan V, Zubrick S, Bower C, Croft M, Valuri G, Jablensky A. Why is the risk of intellectual disability elevated in the children of mothers with schizophrenia and other psychoses? Schizophrenia International Research Society Annual Meeting, Venice, 21-25 June 2008Morgan V, Zubrick S, Bower C, Croft M, Valuri G, Griffith J, Jablensky A. What impact do obstetric complications have on the risk of adverse psychiatric outcomes for the high risk children of mothers with schizophrenia and other psychoses? Schizophrenia International Research Society Annual Meeting, Venice, 21-25 June 2008

Valuri GM, Croft ML, Morgan VA, Jablensky A. The high risk children of mothers with schizophrenia and other severe mental illness: modelling risk from conception to disease. Schizophrenia International

Research Society Annual Meeting, Venice, 21-25 June 2008

Waterreus A and Laugharne J. Screening for the metabolic syndrome in patients on antipsychotic treatment. A proposed algorithm in response to a national survey of current practice in Australia. Australasian Physical And Mental Health Interface Conference Melbourne, 15-16 August 2008

RESEARCH COLLABORATIONS AND ACTIVITIES 2008

International

External Collaborators Affiliation NERU collaborators

Area of collaboration

Outcomes 2008

Prof Tom McNeil University of Lund, Sweden

All Developmental pathways for the children of women with severe mental illness

Ongoing collaborationAdvice on changes to the McNeil-Sjöström Scale

Jean-Paul Selten University of Maastricht, The Netherlands

V Morgan Environmental risk factors for schizophrenia

Joint paper (under review)

A/Prof Kathryn Abel University of Manchester, UK

V Morgan Obstetric complications in women with severe mental illness

Joint publication (letter)

Dr Alberto RossiProf Michella Tansella

University of Verona, Italy

A JablenskyV Morgan

Diagnostic Instrument for Psychosis (DIP) Italian version

Joint paper (in draft)

Dr Alberto Rossi University of Verona, Italy

A JablenskyV Morgan

Incidence of schizophrenia

Planning meeting held for revised protocol

Prof Christina Hultman Karolinska Institute, Sweden

V MorganA Jablensky

Obstetric complications in women with severe mental illness

Joint book chapter (accepted)

Peter McGuffinAnne Farmer

Institute of Psychiatry, UK

A JablenskyV Morgan

Diagnostic Instrument for Psychosis (DIP)

DSM-4 version finalised

National



Outcomes 2008

Prof David Castle University of Melbourne

V MorganA JablenskyG Valuri

Offending patterns and psychiatric illness

Joint publicationPaper in draftJoint conference presentations


V MorganA Jablensky

Women and psychosis Joint publication


A Waterreus Metabolic Syndrome National metabolic survey of Australian psychiatrists completed

Paper in draftProf David Castle University of

MelbourneV Morgan Epidemiology of

schizophreniaJoint book chapter

Prof John McGrath University of Queensland

V MorganA Jablensky

Environmental risk factors for schizophrenia

Joint book chapter (accepted)

Survey of High Impact Psychosis (SHIP) Technical Advisory Committee: Prof Robert Bush Prof Vaughan Carr Prof David Castle Prof Cherrie Galletly Prof Carol Harvey Barbara Hocking Prof Assen Jablensky Prof John McGrath Prof Andrew MackinnonProf Pat McGorry Dr Vera Morgan (Chair)Dr Amanda Neil Anna Waterreus

Universities and health services in NSW, QLD, SA, VIC, WA

V MorganA WaterreusA Jablensky

Survey of High Impact Psychosis (SHIP)

Completion of SHIP Phase 1 work

SHIP Phase 2 funding from Commonwealth secured

Australian Schizophrenia Research Bank (ASRB). Investigators in NSW, QLD, VIC, WA

Universities in NSW, QLD, VIC, WA

A JablenskyV Morgan

Genetic basis of schizophrenia

Input through membership of ASRB scientific and other committees

A/Prof Nadia Badawi University of Sydney / The Children's Hospital at Westmead

M Croft Revisions of McNeil Sjöström Scale (Perth version)Validation of neonatal encephalopathy

Protocol developed for cerebral palsy study

Development of algorithm for neonatal encephalopathy in progress

Revision of McNeil Sjöström Scale (Perth version) in progress

Dr John Keogh John Keogh, Consultant Obstetrician and Gynaecologist, Sydney Adventist Hospital

M Croft Revisions of McNeil Sjöström Scale (Perth version)

Revision of McNeil Sjöström Scale (Perth version) in progress

State



Outcomes 2008

Dr Eve BlairJan de GrootLinda Watson

Institute for Child Health Research

M Croft Validation of the Australian version of the McNeil Sjöström Scale Scoring System using clinical case notes from the Cerebral Palsy International Case Control Study.

A protocol for validation has been developed

Dr Frank MorganAnna FerranteDr Joe Clare

University of WA Crime Research Centre

V MorganG ValuriA Jablensky

Offending patterns and psychiatric illness

Joint publication

Max Maller University of WA Crime Research Centre

V MorganA Jablensky

Software development

Diagnostic Instrument for Psychosis (DIP) software upgraded

Prof Carol BowerProf Steve Zubrick


All Environmental risk factors and developmental pathways in schizophrenia

Joint conference presentations

Dr Danny RockA/Prof Yvonne HaukeProf A Jablensky*

Dept of Health Western Australia / Centre for Clinical Research in Neuropsychiatry

A Jablensky*V Morgan

Follow-up to the 2005 publication in the American Journal of Psychiatry on obstetric complications in women with psychosis

The Centre for Clinical Research in Neuro-psychiatry was funded to design and evaluate an antenatal care program for women with severe mental illness. It was Successfully launched in 2008 as part of clinical practice

Prof Steve Zubrick Institute for Child Health Research

V MorganA Jablensky

Scoping survey of severe mental illness in indigenous communities

Funding from Commonwealth

Dr Helen LeonardJenny Bourke


V MorganA Jablensky

Intellectual disability and psychiatric illness

Joint publication

Dr Geoff SmithDr Theresa Williams

Dept of Health Western Australia

V MorganA Jablensky

-

Dept of Health Western Australia (South Metro)


V MorganA WaterreusJ GriffithA Jablensky

Survey of High Impact Psychosis (SHIP) – WA Catchment

Agreement from services heads for inclusion of their catchments

Dept of Health Western Australia (North Metro)


V Morgan Operational epidemiology

In principle agreement for move to SLA-based catchments

Prof A Jablensky* Centre for Clinical Research in Neuropsychiatry

A Jablensky* WA Family Study of Schizophrenia

Revised protocol and application for register data collection

Dr Jon Laugharne School of Psychiatry and

A Waterreus Metabolic Syndrome Joint Paper (accepted)National metabolic



Outcomes 2008

Clinical Neurosciences

survey of Australian psychiatrists completed

Paper in draft* A Jablensky appears as both external and internal NERU collaborator for those projects that straddle his dual roles as Senior Scientific Consultant: Neuropsychiatric Epidemiology Research Unit and Director: Centre for Clinical Research in Neuropsychiatry

VISITORS 2008: INTERNATIONAL AND NATIONAL

Feb 2008 Prof Tom McNeilProfessor and Chairman, Department of Psychiatric Epidemiology, University Hospital, Lund, Sweden / Adjunct Clinical Professor, School of Psychiatry and Clinical Neurosciences

Mar 2008 Prof Andrew MackinnonProfessor and Head, Statistics Unit, ORYGEN Research Centre, University of Melbourne, Australia

Oct 2008 A/Prof Kathryn AbelReader (Associate Professor) in Psychiatry, Honorary Consultant Psychiatrist and Director of the Centre for Women's Mental Health at the University of Manchester, UK

Nov 2008 Prof Tom McNeilProfessor and Chairman, Department of Psychiatric Epidemiology, University Hospital, Lund, Sweden / Adjunct Clinical Professor, School of Psychiatry and Clinical Neurosciences

Kathryn Abel Tom McNeil

STAFF: FORMAL OFFICES HELD 2008

WA Neuroscience Inc Board member Assen Jablensky

University of Western Australia Senate Senator Vera Morgan

Australasian Society for Psychiatric Research

WA representative Giulietta Valuri

STAFF: CONFERENCE ORGANISING COMMITTEES 2008

Australasian Schizophrenia Conference, Lorne, 23-24 Oct 2008

Scientific Advisory Committee

Vera Morgan

Australasian Schizophrenia Conference, Lorne, 23-24 Oct 2008

Scientific Advisory Committee

Assen Jablensky

3rd World Congress on Women’s Mental Health, Melbourne 16-20 Mar 2008

Organising Committee

Vera Morgan

STAFF: OTHER COMMITTEE MEMBERSHIP 2008

Ingres User Group Inc (WA) Committee Member Maxine Croft

National Survey of High Impact Psychosis (SHIP) Phase 2 Technical Advisory Committee

Chair Vera Morgan

National Survey of High Impact Psychosis (SHIP) Phase 1 Technical Advisory Committee

Chair Vera Morgan

North Metropolitan Area Health Service Mental Health Clinical Services Planning Reference Group

Member Vera Morgan

NTEU National Research Policy Committee

Committee member Vera Morgan

Intellectual Disability Exploring Answers (IDEA) Advisory Council and Ethics Committee


School of Psychiatry and Clinical Neurosciences: School Review Research Activities working group


Australasian Society for Psychiatric Research

Webmaster Giulietta Valuri

Australasian Epidemiology Association, Perth Chapter

Committee member Giulietta Valuri

Perth Epidemiology Group PEGnet mailing list administrator

Giulietta Valuri

VISITORS 2008: TALKS AND RELATED

18 Feb 2008

Prof Tom McNeilProfessor and Chairman, Department of Psychiatric Epidemiology, University Hospital, Lund, Sweden / Adjunct Clinical Professor, School of Psychiatry and Clinical Neurosciences

Workshop Assessing neuromotor deviation on psychopathology, from infancy to adulthood: background and hands-on practice

at: Centre for Clinical Research in Neuropsychiatry

27 Feb 2008


Abnormal neurodevelopment in schizophrenia; past, present and future: Challenges and directions for future research


13 May 2008

Ms Anna FerranteSenior Research Fellow, Crime Research Centre, University of Western Australia

Developmental Pathways in WA Children: A Holistic Approach to inform Early Intervention Strategies

at: Neuropsychiatric Epidemiology Research Unit

12 Aug 2008

Associate Professor Yvonne HauckCurtin University

Healthy Babies for Mothers with Serious Mental Illness: two initiatives


3 Oct 2008 A/Prof Kathryn AbelReader (Associate Professor) in Psychiatry, Honorary Consultant Psychiatrist and Director of the Centre for Women's Mental Health, University of Manchester, UK

Birth weight and adult mental disorder: Combining Scandinavian cohorts


14 Oct 2008

Dr Natalia BilykWA Dept of Health

Round table: Research directions


21 Nov 2008


Fish’s Concept of “Pandysmaturation” and its Physical and Mental Correlates: Investigation in a Prospective High-Risk Study


STAFF: PROFILES

Maxine CROFT BAppSc PhD Twin Child Health registry and she uses linked population data to measure risk of recurrence of reproductive outcomes. She has modified an electronic version of the Mc Neil Sjöström scoring system to include a broader range of maternal diseases. This Perth version will also include longitudinal measures of maternal chronic disease.

Research interests Perinatal epidemiology Schizophrenia Longitudinal measures of maternal health Obstetric complications Database management

Jenny GRIFFITH BAAppSc(Nursing) GradDipArtsCounselling PGDipMentalHealthNursing

MENTAL HEALTH CLINICAL RESEARCH NURSE / WA SITE COORDINATOR FOR NATIONAL SHIP SURVEY: Neuropsychiatric Epidemiology Research Unit+61 8 9224 [email protected]

Jenny Griffith is a registered nurse with 20 years clinical experience, mostly in mental health, over a variety of settings, both rural and urban. Since 1997 Jenny has been mainly working in mental health research. She was an interviewer in the 1998 national Survey of Low Prevalence (Pyschotic) Disorders. From 2004, Jenny has been part of the Pathways Study Team, involved in the collection of qualitative mental health data. Jenny is highly experienced in the use of the Diagnostic Interview for Psychosis (DIP).

Research interests Levels of adversity for children with a

mentally ill parent The experience of severe mental illness,

schizophrenia in particular Community mental health nursing Recovery from severe mental illness

Assen JABLENSKY MD DMedSc FRCPsych

FRANZCPsych

SENIOR SCIENTIFIC CONSULTANT: Neuropsychiatric Epidemiology Research Unit / DIRECTOR: Centre for Clinical Research in Neuropsychiatry+61 8 9224 [email protected]

Assen Jablensky completed his medical degree and training as a psychiatrist in Bulgaria and the UK, and has worked as a researcher and clinician in Switzerland (WHO, Geneva), the US (Stanford University) and, since 1993, Australia, where he is director of the Centre for Clinical Research in Neuropsychiatry of the University of Western Australia in Perth. He has over 290 publications, including articles in peer-reviewed journals, book chapters and monographs. He has been award the Strömgren Prize and medal for psychiatric epidemiology; the Australasian Society for Psychiatric Research Founders Medal, the Organon Senior Research Award, and several other distinctions including Honorary Fellowship of the Royal College of Psychiatrists (UK).

Research interests psychiatric epidemiology genetics of schizophrenia classification of mental disorders

Vera MORGAN BA GradDipEd MSocSc PhD

HEAD: Neuropsychiatric Epidemiology Research Unit / OPERATIONAL EPIDEMIOLOGIST: Centre for Clinical Research in Neuropsychiatry+61 8 9224 [email protected]

Vera Morgan is a psychiatric epidemiologist with a special interest in the epidemiology of schizophrenia and other psychotic disorders. Her current program of research includes a special focus on environmental (especially obstetric) and genetic contributions to the risk of schizophrenia. Her expertise is in the area of epidemiological data design, management and analysis, and she has wide experience using record-linked population health and criminological databases. Her professional roles have included: President of the Australasian Society for Psychiatric Research, Vice-President of the Australasian Epidemiological Association and Chair of the Research Committee of the Mental Health Council of Australia.

Research interests Epidemiology of schizophrenia and other

psychotic disorders Risk factor epidemiology Intellectual disability / cognitive deficit Criminal offending and mental illness

High risk children of parents with severe mental illness

Agung RIONO PhD

EPIDEMIOLOGIST: Neuropsychiatric Epidemiology Research Unit+61 8 9224 [email protected]

Agung Riono comes from Indonesia where he had experience in the teaching of medical physiology and in administration. He started his career in Australia as a research associate at the Lions Eye Institute and School of Medicine and Pharmacology at UWA. His special interest in Epidemiology led him to do a Master in Public Health at UWA. His research interests are minor physical anomalies, their anthropometric study, and risk factors and biological markers (medical screening) for minor physical anomalies. His expertise is in the area of

Screening evaluation for non communicable diseases

Sonal SHAH PhD BA(HonsPsych) RESEARCH ASSOCIATE - MEDICAL AND VITAL STATISTICS: Neuropsychiatric Epidemiology Research Unit+61 8 9224 0290

Sonal Shah recently completed her PhD in the National Health and Medical Research Council Centre of Clinical Research Excellence for the Study of Women's Health. In 2003 she was the recipient of a PhD scholarship within the NHMRC Centre of Clinical Research Excellence. She has a double major in Psychology. She then obtained her Honours degree from the University of Western Australia in the field of cognition. Her honours project was the first to investigate the efficiency of language switching and speaking in Trilinguals. Sonal has received an academic award for the presentation of her work. Her PhD project specifically investigated “Cognition in healthy Australian women and factors affecting change in cognition over time”.

Research interests Impact of early childhood events in the

development of schizophrenia Obstetric complications Statistical data management Women’s health and well being Cognitive function (impact of factors)

Cate SIMPSON BN PGDipClinicalNursing(Midwifery)

PGDipPsychiatricNursing GestaltPsychotherapist MENTAL HEALTH CLINICAL RESEARCHER NURSE: Neuropsychiatric Epidemiology Research Unit+61 8 9224 [email protected]

Cate Simpson is a mental health nursing professional and a Gestalt psychotherapist. Her current role within the Unit involves the application of her clinical expertise to the extraction, assessment and coding of clinical casenotes

Research interests Impact of early childhood events on the

development of schizophrenia

Giulietta VALURI BBus GradDipEpi

EPIDEMIOLOGIST / CRIMINOLOGIST: Neuropsychiatric Epidemiology Research Unit+61 8 9224 0288

[email protected]

Giulietta Valuri is a computer scientist and an epidemiologist who has worked in injury prevention research and with linked WA population databases in both criminology (patterns of offending) and mental health. Her current research focuses on validating mental health diagnoses and measuring and mapping children’s health status using WA data from linked statewide health registers. Her expertise is in the areas of database

management and design, and analytical techniques.

Research interests Epidemiology of schizophrenia and other

psychotic disorders High risk children of parents with severe

mental illness Criminal offending and mental illness

Anna WATERREUS DipNursingStudies NZRN GradDipClinEpid

NATIONAL COORDINATOR FOR SHIP SURVEY: Neuropsychiatric Epidemiology Research Unit+61 8 9347 [email protected]

Anna Waterreus has been involved in psychiatric research for the last 19 years. Currently she is the National Coordinator for the Survey of High Impact Psychosis. She was also involved in the first Australian survey of psychosis (Low Prevalence Psychotic Disorders Survey). Previously she worked in Old Age Psychiatry and has an interest in depression in general practice and the role of nurses. In 2008, with the support of the Royal Australian and New Zealand College of Psychiatrists, she conducted a National survey of psychiatrists and their attitudes to metabolic syndrome.

Research interests Metabolic syndrome Depression & old age Mental health surveys Mental health nursing

Denis Brown (IT) and Stephanie Gee (Administrative Officer)

Appendix 1: Research Funding 1995-2007 ($)

Funding Investigators

Study Title 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007


Morgan VJablensky A

Scoping a national survey of high impact psychosis (SHIP) 78,006

Dept of Health of WA

Morgan VJablensky ASmith GWilliams T

Psychiatric inpatient services database 1990-2006 30,909

Dept of Health of WA

Morgan VJablensky ASmith GWilliams T

High Users of psychiatric inpatient services 1990-2006 21,818


Jablensky AMorgan VBower CZubrick SCroft M


45,772


Children of parents with mental illness: a population-based study

329,950

NH&MRC Jablensky AKalaydjieva LBadcock JKendler KMorgan, VRiley B

Genetics of cognitive impairment in schizophrenia

295,000

260,272

Criminology Research Council

Morgan FMorgan VJablensky AFerrante AValuri

Schizophrenia and offending: area of residence and the impact of social disorganisation and disadvantage

41,934


Study Title 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007


Jablensky AMorgan VBower CZubrick S


55,806 154,386 52,309


Fetal origin of adult disease? A population-based study of the offspring of women with severe mental disorders

172,500

187,500 82,875

UWA Small Research Grant

Morgan V Psychiatric morbidity and mental retardation: A Western Australian record linkage study

14,000

Commonwealth Dept of Health and Aged Care

Jablensky A Follow-up to the Low Prevalence Disorders study 60,000 20,000

Stanley Foundation

Jablensky AZubrick SBower CMorgan VPreston N

Pathways of risk from conception to disease: A population-based study of the offspring of women with bipolar disorder and schizophrenia

111,307

110,426

NHMRC (PHRDC)

Jablensky ACastle DMorgan FFerrante A

Criminal behaviour as an outcome in schizophrenia 78,242 66,152 53,311

NHMRC (PHRDC)

Holman DJablensky AFazio SBass J

Population linkage studies of preventable comorbidity in people with mental illness 34,632 75,849 78,353

Commonwealth Dept of Health and Aged Care

Jablensky A Low Prevalence (Psychotic) Disorders study 523,00

0

Stanley Foundation

Jablensky AZubrick SBower CCastle D

Reproductive pathology in women with schizophrenia and bipolar affective disorder: An epidemiological & clinical study

40,343 65,141


Study Title 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007

Royal Perth Hospital Medical Research Foundation

Jablensky ACastle DPage APetterson B

Influenza epidemics and incidence of CNS disorders in Western Australia 18,311

Appendix 2. Selected publications 1995-2007 (Epidemiology)

2007Journal ArticlesJablensky, A. Does psychiatry need an overarching concept of “mental disorder”? World Psychiatry, 2007, 6, 157-158Jablensky, A. Living in a Kraepelinian world: Kraepelin’s impact on modern psychiatry. History of Psychiatry, 2007, 18, 381-388Jablensky, A. and Morgan, V. Book review: Psychiatric Epidemiology. Searching for the causes of mental disorders, Psychological Medicine, 2007, 37, 905-908Tait RJ. Hulse GK. Waterreus A. Flicker L. Lautenschlager NT. Jamrozik K. Almeida OP. Effectiveness of a smoking cessation intervention in older adults. Addiction. 2007, 102, 148

Books and ChaptersJablensky A. Schizophrenia and related psychoses. In D. Bhugra, K. Bhui (eds) Textbook of Cultural Psychiatry. Cambridge University Press, 2007, 207-223Mendelson G, Jablensky A. What does psychiatry encompass? In S Bloch, B Singh (eds) Foundations of Clinical Psychiatry, 3rd edition, Melbourne University Press, 2007, 69-90

2006Journal ArticlesAlmeida OP. Waterreus A. Hankey GJ. Preventing depression after stroke: Results from a randomized placebo-controlled trial. Journal of Clinical Psychiatry. 2006, 67, 1104-9

Castle, D.J., Jablensky, A., McGrath, J.J., Carr, V., Morgan, V., Waterreus, A., Valuri, G., Stain, H., McGuffin, P. and Farmer, A. The diagnostic interview for psychoses (DIP): development, reliability and applications, Psychological Medicine, 2006, 36, 69-80Davis SR, Goldstat R, Papalia M, Shah S, Kulkarni J, Donath S, Bell RJ. Effects of aromatase inhibin on sexual function and wellbeing in postmenopausal women treated with testosterone: a randomized placebo controlled trial. Menopause, 2006 13(1) 37-45Jablensky, A. Historical dictionary of psychiatry, Psychological Medicine, 2006, 36, 277-278Jablensky A. The epidemiology of schizophrenia, ed by RM Murray, P. Jones, E. Susser, J van Os, M Cannon (book review). Australian and New Zealand Journal of Psychiatry, 2006, 40, 503Morgan, V., Korten, A. and Jablensky, A. Modifiable risk factors for hospitalization among people with psychosis: evidence from the National Study of Low Prevalence (Psychotic) Disorders, Australian and New Zealand Journal of Psychiatry, 2006, 40, 683-690Morgan, V.A. and Jablensky, A.V. Exploring the role of reproductive pathology in the etiology of schizophrenia: What happens when mothers with schizophrenia give birth?, Directions in Psychiatry, 2006, 26, 1-15Shah, S, Bell, RJ, Davis SR. Homocysteine and cognitive decline after menopause. Climacteric, 2006 9 (2) 77-87Shah S. Bell RJ, Savage G, Ades R, Papalia M-A, Kulkarni J, Donath S, Davis S. Testosterone aromatization and cognition in

women: a randomized placebo controlled trial. Menopause, 2006 13 (4) 600-608

2005Journal ArticlesJablensky, A. Categories, dimensions and prototypes: Critical issues for psychiatric classification, Psychopathology, 2005, 38, 201-205Jablensky, A. The long and winding road of schizophrenia research, Epidemiologia E Psichiatria Sociale, 2005, 14, 179-183Jablensky, A. Boundaries of mental disorders, Current Opinion in Psychiatry, 2005, 18, 653-658Jablensky, A.V., Morgan, V., Zubrick, S.R., Bower, C. and Yellachich, L.A. Pregnancy, delivery, and neonatal complications in a population cohort of women with schizophrenia and major affective disorders, American Journal of Psychiatry, 2005, 162, 79-91Kaiser, R., Lohrer, F., Morgan, V. and Hambrecht, M. Changes in the pattern of substance abuse after the onset of psychosis, Australian and New Zealand Journal of Psychiatry, 2005, 39, 467-472Morgan, V.A., Mitchell, P.B. and Jablensky, A.V. The epidemiology of bipolar disorder: sociodemographic, disability and service utilization data from the Australian National Study of Low Prevalence (Psychotic) Disorders, Bipolar Disorders, 2005, 7, 326-337Rossi, A., Morgan, V., Amaddeo, F., Sandri, M., Tansella, M. and Jablensky, A. Psychiatric out-patients seen once only in South Verona and Western Australia: a comparative case-

register study, Australian and New Zealand Journal of Psychiatry, 2005, 39, 414-422Valuri G, Stevenson M, Finch C, Hammer B, Elliot B. The Validity of a Four Week Self-Recall of Sports Injuries. Injury Prevention. 2005, 11, 135-137

Books and ChaptersCastle, D.J. and Jablensky, A.V. Diagnosis and classification in psychiatry, Core Psychiatry, ed Wright, P, Stern, J & Phelan, M., Edinburgh, Elsevier Saunders, 2005, 507-515Jablensky, A. Disease and health in the cultural context, Understanding the Global Dimensions of Health, ed Gunn, S.W.A., Mansourian, P.B., Davies, A.M., Piel, A., Sayers, B.McA., New York, Springer Science & Business Media Inc., 2005, 231-239

ReportsFerrante AM, Loh NSN, Maller MG, Valuri GM, Fernandez JA. Crime and Justice Statistics for Western Australia: 2004. Statistical Report. Crime Research Centre, University of Western Australia, Dec 2005

2004Journal ArticlesAlmeida OP. Waterreus A. Spry N. Flicker L. Martins RN. One year follow-up study of the association between chemical castration, sex hormones, beta-amyloid, memory and depression in men. Psychoneuroendocrinology. 2004, 29, 1071-81.Blagg H & Valuri G. Aboriginal Community Patrols in Australia: Self-Policing, Self Determination and Security. Policing & Society 2004, 14, 313-328.Blagg H & Valuri G. Self-policing and community safety: the work of Aboriginal Community Patrols in Australia. Current Issues in Criminal Justice 2004, 15, 205-219Glasson, E.J., Bower, C., Petterson, B., de Klerk, N.,

Chaney, G. and Hallmayer, J.F. Perinatal factors and the development of autism: a population study, Archives of General Psychiatry, 2004, 61, 618-627Hansen J, Alessandri, PT, Croft ML, Burton, PR, de Klerk NH. The Western Australian Register of childhood multiples: Effects of questionnaire design and follow-up protocols on response rates and representativeness. Twin Research 2004, 7, 149-161Jablensky A. Researching psychiatry in Western Australia. Australian and New Zealand Journal of Psychiatry 2004, 38, 306-315Jablensky A. The syndrome – an antidote to spurious comorbidity? World Psychiatry 2004, 3, 24-25Kavanagh, D.J., Waghorn, G., Jenner, L., Chant, D.C., Carr, V., Evans, M., Herrman, H., Jablensky, A. and McGrath, J.J. Demographic and clinical correlates of comorbid substance use disorders in psychosis: multivariate analyses from an epidemiological sample, Schizophrenia Research, 2004, 66, 115-124

ReportsCroft M and Ferrante A. A Review of the Data Matching Processes of the Cervical Cytology Registry for the Western Australian Cervical Cancer Prevention Program. Commissioned by the Women’s Cancer Prevention Program of the WA Department of Health 2004Fernandez JA, Ferrante AM, Loh NSN, Maller MG, Valuri GM. Crime and Justice Statistics for Western Australia: 2003. Statistical Report. Crime Research Centre, University of Western Australia, Dec 2004Leonard H, Petterson B, Bourke J, Morgan V, Glasson E, Bower C. Inaugural report of the idEA database - Intellectual disability in Western Australia. Perth Western Australia, Institute for Child Health Research, 2004

2003Journal ArticlesJablensky, A.V. and Kalaydjieva, L.V. Genetic epidemiology of schizophrenia: phenotypes, risk factors, and reproductive behaviour, American Journal of Psychiatry, 2003, 160, 425-429 Kendell, R.V. and Jablensky, A. Distinguishing between the validity and utility of psychiatric diagnoses, American Journal of Psychiatry, 2003, 160, 4-12 Lawrence, D.M., Holman, C.D.J., Jablensky, A.V. and Hobbs, M.S.T. Death rate from ischaemic heart disease in Western Australian psychiatric patients 1980-1998, British Journal of Psychiatry, 2003, 182, 31-36 Morgan, V., Janca, A. and Jablensky, A. Psychotic disorders in Australia: patients respond to national survey results, European Psychiatry, 2003, 18, 142 Morgan, V. Two-phase sampling designs for rare outcomes, Australasian Epidemiologist, 2003, 10, 2-3

Books and ChaptersJablensky, A. The epidemiological horizon, Schizophrenia, ed Hirsch, S.R., Weinberger, D.R., England, Blackwell Publishing, 2003, 203-231 Jablensky, A. Diagnosing schizophrenia: a personal view, Schizophrenia, ed Maj, M., Sartorius, N., England, John Wiley & Sons Ltd, 2003, 58-61

ReportsBlagg H, Valuri G. An Overview of Night Patrol Services in Australia. Attorney-General’s Department, Crime Prevention Unit. Mar 2003.

2002Journal Articles

Castle D, Morgan V, Jablensky A. Antipsychotic use in Australia: the patients’ perspective. Australian and New Zealand Journal of Psychiatry 2002, 36, 633-641Castle D, Morgan V. Attitudes to depot antipsychotics. Letter. British Journal of Psychiatry 2002, 180, 187-188Croft ML, Read AW, de Klerk N, Hansen J, Kurinczuk JJ. Population based ascertainment of twins and their siblings, born in Western Australia 1980 to 1992, through the construction and validation of a maternally linked data base of siblings. Twin Research 2002, 5, 317-23Dunn JC. Almeida OP. Barclay L. Waterreus A. Flicker L. Latent semantic analysis: a new method to measure prose recall. Journal of Clinical & Experimental Neuropsychology. 2002, 24, 26-35Gureje O, Herrman H, Harvey C, Morgan V, Jablensky A. The Australian National Survey of Psychotic Disorders: profile of psychosocial disability and its risk factors. Psychological Medicine 2002, 32, 639-647Jablensky A. Research methods in psychiatric epidemiology: an overview. Australian and New Zealand Journal of Psychiatry 2002, 36, 297-310Jablensky A. The classification of personality disorders: Critical review and need for rethinking. Psychopathology 2002, 35, 112-116Morgan V. Psychiatric Epidemiology. Guest editorial. Australasian Epidemiologist 2002, 9 (2), 1-2Morgan V. What can record linkage contribute to psychiatric epidemiology? Australasian Epidemiologist 2002, 9 (2), 25-29Morgan V, Janca A, Jablensky A. National study of psychotic disorders in Australia: Feedback from individuals with psychosis. The Hong Kong Journal of Psychiatry 2002, 12, 8-12.

Books and Chapters

Jablensky, A., & Kendell, R. E. Criteria for assessing a classification in psychiatry. In M. Maj (Ed.), The Future of Psychiatric Diagnosis and Classification. World Psychiatric Association. 2002Jablensky, A., & Cooper, J. E. Classification of dementia and other organic conditions in ICD-10. In J. R. M. Copeland, M. T. Abou-Saleh, & D. G. Blazer (Eds.), Principles and Practice of Geriatric Psychiatry (Vol. 2nd edition). Chichester: Wiley, 2002

ReportsMorgan V, Castle D, Jablensky A. The use of psychopharmacological and other treatments by persons with psychosis: Self-reported data from the National Study of Low Prevalence (Psychotic) Disorders. Bulletin 4. National Mental Health Strategy. Canberra, Australian Commonwealth Department of Health and Ageing, 2002Valuri G, Indermaur D, Ferrante A. The Criminal Careers of Drug Offenders in Western Australia: A study of the recidivism and criminal history of those arrested for a drug offence in Western Australia between 1989 and 1999. Report by the Crime Research Centre, University of Western Australia, May 2002.

2001Journal ArticlesAlmeida OP. Waterreus A. Spry N. Corica T. Martins G. Martins RN. Flicker L. Effect of testosterone deprivation on the cognitive performance of a patient with Alzheimer's disease. International Journal of Geriatric Psychiatry. 2001, 16, 822-825Morgan V, Jablensky A, Castle DJ . Season of birth in schizophrenia and affective psychoses in Western Australia 1916-1961. Acta Psychiatrica Scandinavica, 2001, 104, 138-147Jablensky A. Classification of

nonschizophrenic psychotic disorders: A historical perspective. Current Psychiatry Reports 2001, 3, 326-331Gandy S. Almeida OP. Fonte J. Lim D. Waterreus A. Spry N. Flicker L. Martins RN. Chemical andropause and amyloid-beta Journal of the American Medical Association. 2001, 285, 2195-2196Gureje O, Herrman H, Harvey C, Trauer T, Jablensky A. Defining disability in psychosis: performance of the diagnostic interview for psychosis – disability module (DIP-DIS) in the Australian National Survey of Psychotic Disorders. Australian and New Zealand Journal of Psychiatry 2001, 35, 846-851Jablensky A, Lawrence D. Schizophrenia and cancer: Is there a need to invoke a protective gene? Archives of General Psychiatry 2001, 58, 579-580.

Books and ChaptersJablensky, A., Johnson, R., Bunney, W., et al. Neurological, Psychiatric, and Developmental Disorders; Meeting the Challenge in the Developing World. Washington DC: National Academy Press, 2001Jablensky A. Symptoms of schizophrenia. In Henn F., Sartorius N., Helmchen H., Lauter H. (eds) Contemporary Psychiatry, vol 3. Springer, Berlin, 2001, 3-36.Jablensky A. Schizophrenia. In: Neurological, Psychiatric, and Developmental Disorders. Meeting the Challenge in the Developing World. Institute of Medicine, National Academy of Science, Washington DC, 2001Mendelson, G., & Jablensky, A. What does psychiatry encompass? In S. Bloch & B. Singh (Eds.), Foundations of Clinical Psychiatry (2nd ed). Melbourne: Melbourne University Press, 2001, 63-81

ReportsMorgan, V., Korten, A., Valuri, G., Waterreus, A. and Jablensky,

A on behalf of the Low Prevalence Disorders Study Group. National Survey of Mental Health and Wellbeing. People Living with Psychotic Illness: An Australian Study 1997-98. Confidentialised Unit Record File. Technical paper. September 2001Valuri G, Morgan V, Jablensky A. Deriving a Research Diagnosis from a Mental Health Register. Report to Western Australian Department of Health. Perth: University of Western Australia Department of Psychiatry and Behavioural Science; 7 March 2001.

2000Journal ArticlesHansen J, de Klerk N, Croft ML, Alessandri P, Burton P. The Western Australian Twin Child Health (WATCH) Study: work in progress. Australasian Epidemiologist 2000, 7, 2Jablensky A. The concept of schizophrenia: pro et contra. Epidemiologia e Psichiatria Sociale 2000, 8, 242-247Jablensky A., McGrath J., Herrman H., Castle D., Gureje O., Evans M, Carr V., Morgan V., Korten A., Harvey C. Psychotic disorders in urban areas: an overview of the Study on Low Prevalence Disorders. Australian and New Zealand Journal of Psychiatry 2000, 34, 221-236Jablensky A. Prevalence and incidence of schizophrenia spectrum disorders: implications for prevention. Australian and New Zealand Journal of Psychiatry 2000, 34, Suppl S26-S34Jablensky A. Epidemiology of schizophrenia: the global burden of disease and disability. European Archives of Psychiatry and Clinical Neuroscience 2000, 250, 274-85Lawrence D, Holman CD, Jablensky A, Threlfall TJ, Fuller SA Excess cancer mortality in Western Australian psychiatric patients due to higher case

fatality rates. Acta Psychiatrica Scandinavica 2000, 101, 382-388Lawrence D, Almeida O, Hulse G, Jablensky A Suicide and attempted suicide among older adults in Western Australia. Psychological Medicine 2000, 30, 813-821Morgan V, Janca A. Revisiting the journal impact factor. Australasian Psychiatry 2000, 8, 230-235

Books and ChaptersJablensky A Epidemiology of schizophrenia. In Gelder M, Andreassen A, Lopez-Ibor J (eds) New Oxford Textbook of Psychiatry, Vol 1. Oxford University Press, Oxford, 2000, 585-599.Jablensky A Course and prognosis of schizophrenia. In Gelder M, Andreassen A, Lopez-Ibor J (eds) New Oxford Textbook of Psychiatry, Vol 1. Oxford University Press, Oxford, 2000, 612-621.

1999Journal ArticlesBlanchard MR. Waterreus A. Mann AH. Can a brief intervention have a longer-term benefit? The case of the research nurse and depressed older people in the community. International Journal of Geriatric Psychiatry. 1999, 14(9):733-8Finch C, Valuri G, Ozanne-Smith J. Injury Surveillance During Medical Coverage of Sporting Events – Development and Testing of a Standardised Data Collection Form. Journal of Science and Medicine in Sport 1999, 2, 42-56Jablensky A. Schizophrenia: epidemiology. Current Opinion in Psychiatry 1999, 12, 19-28Jablensky A. The conflict of the nosologists: views on schizophrenia and manic depressive illness in the early part of the 20th century. Schizophrenia Research 1999, 39, 95-100

Jablensky A. The Forest and the Trees. Personal History & Health. The Midtown Longitudinal Study 1954-1974, by Leo Srole and Ernest Joel Millman (book review). Contemporary Psychology / APA Review of Books 1999, 45, 221-223Jablensky A. The nature of psychiatric classification: issues beyond ICD-10 and DSM-IV. Australian and New Zealand Journal of Psychiatry 1999, 33, 137-144Lawrence D.M., Holman D.J, Jablensky A., Fuller S.A. Suicide rates in psychiatric in-patients: an application of record linkage to mental health research. Australian and New Zealand Journal of Public Health 1999, 23, 468-470Jablensky A Psychiatric epidemiology and the global public health agenda. International Journal of Mental Health 1999, 28, 6-14

Books and ChaptersJablensky A. The concept of somatoform disorders: A comment on the mind-body problem in psychiatry. In: Ono Y et al (Eds) Somatoform Disorders: A Worldwide Perspective. Springer, Tokyo, 1999, 3-10Jablensky A Beyond ICD-10 and DSM-IV: issues in contemporary psychiatry. In Promoting Mental Health Internationally. Ed by de Girolamo G., Eisenberg L. and Goldberg D.P. Gaskell, London, 1999, 47-56Jablensky A Diagnosing schizophrenia – a personal view. In Maj M. (ed) Evidence and Experience in Psychiatry, vol. 2, World Psychiatric Association, 1999Jablensky A. The 100-year epidemiology of schizophrenia. In Search for the Causes of Schizophrenia, Vol. IV, ed by W.F. Gattaz and H. Häfner. Steinkopff, Darmstadt, 1999, 3-19

ReportsCroft M. Creation of a Patient

Master Index for Tasmania’s Mental Health Services. Commissioned by Tasmania’s Department of Health and Human Services 1999Jablensky A, McGrath J, Herrman H, Castle D, Gureje O, Morgan V, Korten, A. People Living with Psychotic Illness: An Australian Study 1997-98 - An Overview. National Survey of Mental Health and Wellbeing: Bulletin 1. National Mental Health Strategy. Canberra, Australian Commonwealth Department of Health and Aged Care, 1999.Jablensky A, McGrath J, Herrman H, Castle D, Gureje O, Morgan V, Korten, A. People Living with Psychotic Illness: An Australian Study 1997-98. National Survey of Mental Health and Wellbeing: Report 4. National Mental Health Strategy. Canberra, Australian Commonwealth Department of Health and Aged Care, 1999.

1998Journal ArticlesFinch C, Valuri G, Ozanne-Smith J. Sports and Active Recreation Injuries in Australia - Evidence from Emergency Department Presentations. British Journal of Sports Medicine. 1998, 32, 220-225

ReportsSomerford P, Pinder T, Valuri G, Price S, Stevens M. Bicyle Injury Hospitalisations and Deaths in Western Australia 1981 – 1995. Injury Control Program - Disease Control, Health Department of Western Australia, July 1998Croft M. Record linkage of the NSW Registrar General’s registrations of deaths to the NSW Inpatient statistics collection records for 1995/96 coronary artery bypass graft patients. Commissioned by NSW Health Department 1998

1997

Journal ArticlesJablensky A. The 100-year epidemiology of schizophrenia. Schizophrenia Research 1997, 28, 111-125Jablensky A. Organic origins of psychoses. Brain Pathology 1997, 7, 1043-1046Jablensky A., Cole S.W. Is the earlier age at onset of schizophrenia in males a confounded finding? British Journal of Psychiatry 1996, 170, 234-240Morgan V, Castle D, Page A, Fazio S, Gurrin L, Burton P, Montgomery P, Jablensky A. Influenza epidemics and the incidence of schizophrenia, affective disorders and mental retardation in Western Australia: no evidence of a major effect. Schizophrenia Research 1997, 26, 25-39Stanley FJ, Read AW, Kurinczuk JJ, Croft ML, Bower C. A population maternal and child health research data base for research and policy evaluation in Western Australia. Seminars in neonatology 1997, 2,195-201

Published conference proceedingsValuri, G. Finch, C., Ozanne-Smith, J. A Standardised Data Collection Methodology for Sports Injury Surveillance. Computerised Data Entry and Analysis System. In: McGuiness B, Leeder T (eds). Making It Happen. Proceedings of the Fourth National Health Informatics Conference. Melbourne, Australia 19th - 21st August 1996, 45- 49

Books and ChaptersJablensky A. International perspective in transcultural mental health. In: Ferguson B., Barnes D. (eds) Perspectives on Transcultural Mental Health. Transcultural Mental Health Centre, Sydney, 1997, 1-12

ReportsCroft M, Ferrante A. The corporate data warehouse project data matching project. Commissioned by WA Ministry of

Justice 1997Croft M. A description of the availability, accessibility and utility of the major health data bases relevant to research into the incidence, prevalence, management and health outcomes of diabetes in Western Australia . Commissioned by Diabetes Australia (WA) 1997Croft M. A Proposal to establish a diabetes registry in Western Australia using record linkage. Commissioned by Diabetes Australia (WA) 1997Day, L., Valuri, J., Ozanne-Smith, J. General Practice Injury Surveillance in the Latrobe Valley. Monash University Accident Research Centre Report No. 113, May 1997Waterreus A. Mann A. Blanchard M. Aquilina C. Out of the darkness; a training package in the recognition and management of depression in older people for primary health care workers. 1997. Institute of Psychiatry, London, England.

1996Journal ArticlesJablensky A. (1996) Books reconsidered: General Psychopathology by Karl Jaspers. Australian & New Zealand Journal of Psychiatry 1996, 30, 885-888Morgan V, Castle D, Jablensky A. Seasonality of birth in Western Australia. Letter. British Journal of Psychiatry 1996, 168, 521

Books and ChaptersJablensky A. (1996) Diagnosis and classification in a developing country. In: Tantam D., Appleby L. and Duncan A. (eds) Psychiatry for the Developing World. Gaskell, London, 1996, 27-47

ReportsCroft M. A feasibility study of the probabilistic record linkage of the NSW Road Traffic

Authority’s Road Traffic Accident data base to the NSW Inpatient statistics collection records for 1993/94. Commissioned by NSW Health Department 1996Finch, C., Valuri G., McGrath, A. Pitching Injury Prevention to Baseballers and Softballers: A Review of the Literature. Monash University Accident Research Centre Report No. 106, Dec 1996

1995Journal ArticlesBlanchard, M. R; Waterreus, A; Mann, A. H. The effect of primary care nurse intervention upon older people screened as depressed. International Journal of Geriatric Psychiatry. 1995, 10, 289-298.Jablensky A. Schizophrenia: recent epidemiological issues. Epidemiologic Reviews 1995, 17, 10-20Jablensky A. Comments on "Prenatal exposure to influenza epidemics and risk of mental retardation" by Takei N. et al. European Archive of Psychiatry and Clinical Neuroscience 1995, 245, 262-263Jablensky A. Kraepelin's legacy: paradigm or pitfall for modern psychiatry? European Archive of Psychiatry and Clinical Neuroscienc, 1995, 245, 186-188Jablensky A. Diagnosis and classification in a developing country. Malaysian Journal of Psychiatry 1995, 3, 1-8

Books and ChaptersJablensky A. Future perspectives on concepts of disease. In: WHO-CIOMS, The Impact of Scientific Advances on Future Health, World Health Organization, Geneva, 65-73.Jablensky A. Schizophrenia: the epidemiological horizon. In: Hirsch S.R. and Weinberger D. (eds) Schizophrenia. Blackwell, London , 206-252.Jablensky A., Eaton W.W. Schizophrenia. In: Jablensky A.

[ed] Epidemiological Psychiatry. Bailliere Tindall, London, 283-306.

ReportsCroft M. Report on the linkage of the NSW Neonatal Intensive Care Unit Study data base to the 1992 NSW Midwives’ Data Collection. Commissioned by NSW Health Department 1995Croft M. Report on the linkage of the NSW Neonatal Emergency Transport Service data base to the 1992 NSW Midwives’ Data Collection. Commissioned by NSW Health Department 1995Day, L., Valuri, J., Ozanne-Smith, J. General Practice Injury Surveillance in the Latrobe Valley. Draft Report on the First Six Months. Monash University Accident Research Centre Report. Sept 1995.Valuri, G. Hazard 22 Product Related Injuries - A Selection, Domestic Architectural Glass Injuries, Victorian Injury Surveillance System. 1995, March, 2-5

Contact details

Neuropsychiatric Epidemiology Research UnitSchool of Psychiatry & Clinical Neurosciences

University of Western Australia M571Level 3, Medical Research Foundation Building,

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Western Australia 6000

Contact detailsMs Stephanie Gee

PH: +61-8-9224 0290 FAX: +61-8-9224 0285

EMAIL: [email protected]

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