(3408983) 2.2 fc autism control fgr1op2. (3806939) 1.4 fc autism control smad2

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(340898 3) 2.2 FC autism control FGR1OP 2

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Page 1: (3408983) 2.2 FC autism control FGR1OP2. (3806939) 1.4 FC autism control SMAD2

(3408983)2.2 FC

autism

control

FGR1OP2

Page 2: (3408983) 2.2 FC autism control FGR1OP2. (3806939) 1.4 FC autism control SMAD2

(3806939)1.4 FC

autism

control

SMAD2

Page 3: (3408983) 2.2 FC autism control FGR1OP2. (3806939) 1.4 FC autism control SMAD2

(3960417)1.3 FC

autism

control

PLA2G6

Page 4: (3408983) 2.2 FC autism control FGR1OP2. (3806939) 1.4 FC autism control SMAD2

(2428357)2 FC

autism

control

ST7L

Page 5: (3408983) 2.2 FC autism control FGR1OP2. (3806939) 1.4 FC autism control SMAD2

(3536962)1.8 FC

autism

control

KTN1

Page 6: (3408983) 2.2 FC autism control FGR1OP2. (3806939) 1.4 FC autism control SMAD2

Supplementary Figure 4S. Examples of similar differentially expressed alternatively expressed genes in LCL (our study) compared with ASD brain samples. Differential alternative splicing of 212 genes has been recently identified in autism brain samples using high-throughput RNA sequencing (RNA-Seq) (Voineagu et al., 2011). We found differential exon expression for 78 of these genes in our autism group compared with controls (Supplementary Table 2A). Plots representing exon level expression for five genes whereby the same exon was differentially expressed in both LCL and autism brain samples are shown. Graphs were generated by Partek.