4. basic principles of growth
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Chondrogenesis
Formation of cartilage:
Chondroblasts produce intercellular matrix
Cells become encased in matrix and becomechondrocytes
Chondrocytes enlarge, divide and produce matrix(interstitial growth)
New chondrocytes differentiate from surfacemembrane (appositional growth)
Matrix remains uncalcified
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Formation
Bone formation from undifferentiated mesenchymal
tissue
Process begins in 8th week IUL
Osteoblasts from ectomesenchyme produce osteoidtissue
Cells become encased in matrix and becomeosteocytes
Blood vessels retained within spaces and develophaversian system
Osteocytes lose capacity to produce osteoid
Periosteum produces more osteoid tissue(appositional growth)
Osteoid calcifies
Essential membrane covers bone
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Inferior Relocation of Palate
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