4672028

C O M P O S I T I O N S A N D M E T H O D F O R S I M U L T A N E O U S M U L T I P L E

A R R A Y O F A N A L Y T E S U S I N G R A D I O I S O T O P E C H E L A T E

L A B E L S

Douglas Olson assigned to 1CN Micromedic Systems lnc

Compounds useful in a simultaneous multiple assay for analytes such as steroids, proteins, pep- tides, carbohydrates or drugs. The compound or compounds are prepared by labelling an in- dividual analyte with a radioisotope through a chelating agent to form a coordinated com- pound. The assay uses one or more chelated labelled analytes with one or more labelled analytes wherein each radioisotope is different.

4672031

M E T H O D O F T R E A T I N G T H E E F F E C T I V E N E S S O F C O L L A G E N -

I N H I B I T I N G C O M P O S I T I O N S

PATENT ABSTRACTS 339

seaiingly against the plate (I) with the aid of a liquid-sealing and opaque collection vessel (6). The plate (1) includes a transparent portion (7) which is situated above or opposite the opening (3) of the chamber (2). There is a means (8) above the portion (7) for registering a light flux caused by luminescence, said means (8) being ac- commodated in an opaque housing (I 3) sealing against the plate (I), and there is an aperture plate (9) displaceably arranged above the por- tion (7) between the plate (1) and the means (8) to prevent unintentional exposure of the means. Bacteria are enriched from a liquid sample on the filter (4), a chemical treatment of the bacteria on the filter provides light in the chamber by luminescence, the luminescence in the chamber being dependent on the chemicals being retained in the chamber by filter (4). Registration of the light taking place electronically or on a light- sensitive, rapidly developing, photographic film, when the light image which the luminescence ac- hieves is either registered electronically or is read off on the film in the form of a large or smaller light patch or in the form of a grey tone which can be compared with a grey tone scale to define a measure of the bacteria content.

Darwin J Prockop assigned to University of Medicine and Dentistry of New Jersey

There is disclosed the use of a collagen inhibiting composition including in polymeric form select analogs of proline and processes for the manu- facture and use of such a collagen-inhibiting composition to reduce scar tissue formation. There is also disclosed a method for testing the effectiveness of collagen-inhibiting composi- tions.

4672039

A P P A R A T U S F O R R E G I S T E R I N G T H E P R E S E N C E O F B A C T E R I A ,

P A R T I C U L A R L Y IN F I E L D C O N D I T I O N S

Eina Lundblom, Rockneby, Sweden assigned to AB Sangtec Medical

The invention relates to an apparatus for registering the presence of bacteria, particularly under field conditions. The apparatus includes a plate (1), in which there is formed a luminescence chamber (2) which is defined at its opening (3) by a support lattice (5) carrying a filter (4), the lat- tice opening out into and being carrying

4672040

M A G N E T I C P A R T I C L E S F O R U S E IN S E P A R A T I O N S

Lee Josephson assigned to Advanced Magnetics Inc

Methods are provided for the use of magnetically responsive particles in systems in which the separation of certain molecules, macromolecules and cells from the surrounding n~edium is desirable. The magnetically respon- sive particles may be coupled to a wide variety of molecules. The magnetic particles can be dis- persed in aqueous media without rapid settling and conveniently reclaimed from media with a magnetic field. Preferred particles do not become magnetic after application of a magnetic field and can be redispersed and reused.

4672691

B U L K V O L U M E F E R M E N T E R

Claude De Garie, Albert Cocci, Robert C Lan- dine, Fredericton, Canada assigned to Adi Limited

A fermentation pond has a cover and gas- collection system that includes a gas-