4/7/14%11:06%pm h,p://fac.ksu.edu.sa/aalroqi/home%...

94
4/7/14 11:06 PM h,p://fac.ksu.edu.sa/aalroqi/home 72

Upload: others

Post on 03-Feb-2021

0 views

Category:

Documents


0 download

TRANSCRIPT

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   72  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   73  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   74  

  • Clinical  features  of  parapharyngeal  abscess  

    •  Systemic  manifestaFons  

    •  Pain,  trismus,  swelling    

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  75  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   76  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   77  

  • CLINICAL  FEATURES  

    •  Systemic  manifestaFons  

    •  Pain,  trismus,  swelling  

     

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  78  

  • INVESTIGATION  •  Laboratory  and  bacteriology  •  CT  •  MRI  

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  79  

  • PRINCIPLES  OF  TREATMENT  

    •  Secure  the  airway  

    •  AnFmicrobial  therapy  

    •  Surgical  drainage  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   80  

  • DRAINAGE  OF  PARAPHARYNGEAL  ABSCESS  

    •  External  cervical  incision    

    •  In  order  to  avoid  injury  to  

    the  great  vessels  

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  81  

  • 4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  82  

  • COMPLICATIONS  OF  ACUTE  TONSILLITIS  

    •  General:  – Acute  rheumaFsm  – Acute  glomerulonephriFs  – SepFcaemia  

    •  Local:  – PeritonsilliFs  &  peritnosillar  abscess  (  Quinsy)  – Neck  Abscess  – Parapharyngeal    abscess  – Retropharyngeal  abscess  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   83  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   84  

  • Anatomy  of  retropharyngeal  space  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   85  

  • ACUTE  RETROPHARYNGEAL  ABSCESS  

    •  Due   to   suppuraFon   of   the   retropharyngeal   lymph  nodes  present  in  the  retrophayngeal  space  

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  86  

  • CLINICAL  FEATURES  

    •  Systemic  manifestaFons  •  Respiratory  obstrucFon  

    •  Odynophagia  &  Dysphagia  

    •  Swelling    of  posterior  pharyngeal  wall  (usually  unilateral)  

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  87  

  • INVESTIGATION  

    •  Laboratory  and  bacteriology  •  Plain  X-‐rays  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   88  

  • Normal Retropharyngeal abscess

    PLAIN  X-‐RAYS  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   89  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   90  

  • CT  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   91  

  • MRI  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   92  

  • TREATMENT  OF  ACUTE  RETROPHAYNGEAL  ABSCESS  

    •  Secure  airway  

    •  AnFmicrobial  

    •  Surgical  drainage  

    – Trans  oral  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   93  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   94  

  • CHRONIC  RETROPHARYNGEAL  ABSCESS  

    •  Tuberculous  (cold  abscess)  

    •  Usually  due  to  TB  spines  but  may  be  

    secondary  to  TB  lymphadenFs  

    •  Symptoms  are  insidious  

    •  Treatment  is    by  anF  tuberculous  

    medicaFon,  repeated  aspiraFon  and  

    external  drainage  4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  95  

  • Ludwig’s  Angina  

    •  InfecFon  of  the  submandibular  space  

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  96  

  • Causes  of  Ludwig’s  Angina  

    •  Usually  secondary  to  dental  infecFon  or  

    trauma  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   97  

  • PresentaFon  of  Ludwig’s  Angina  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   98  

  • TREATMENT  

    •  Secure  airway  •  Most  cases  respond  to  anFbioFcs  •  Drainage  may  be  needed  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   99  

  • ComplicaFons  of  neck  spaces  infecFons    

    •  Respiratory  obstrucFon  

    •  Spontaneous  rupture  (inhalaFon  

    pneumonia    

    •  Extension  of  infecFon  

    –   Other  spaces  

    –  CaroFd  &  internal  jugular  

    – MediasFniFs  

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  100  

  • ACUTE  INFECTIONS  OF  THE  OROPHARYNX  

    •  Acute  tonsilliFs  •  Acute  non-‐specific  pharyngiFs  •  Acute  diphtheria  •  InfecFous  mononueuclosis  •  Vincent’s  Angina  •  Scarlet  fever  •  Moniliasis  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   101  

  • ACUTE  NONSPECIFIC  PHARYNGITIS  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   102  

  • ACUTE  INFECTIONS  OF  THE  OROPHARYNX  

    •  Acute  tonsilliFs  •  Acute  non-‐specific  pharyngiFs  •  Acute  diphtheria  •  InfecFous  mononueclosis  •  Vincent’s  Angina  •  Scarlet  fever  •  Moniliasis  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   103  

  • ACUTE  DIPHTHERITIC  PHARYNGITIS  

    •  A  severe  infecFon  caused  by  Corynebacterium  diphtheriae  

    •  Affect  children  at  age  2-‐5  years  •  Spread  by  droplets  or  contaminated  arFcles  

    •  The  incidence  has  fallen  markedly  because  of  immunizaFon  

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  104  

  • PATHOLOGY  

    •  Local  grayish  membrane  (composed  of    fibrin,  leukocytes,  and  cellular  debris)  

    •  Exotoxins  travels  to  heart  and  nervous  system  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   105  

  • CLINICAL  MANIFESTATIONS  

    •  Systemic  symptoms  due  to  the  exotoxins  

    •  Toxemia  •  Mild  fever  •  Tachycardia  •  Paralysis  

    •  Local  manifestaFons  –  Sore  throat  – Membrane  – Marked  lymphadenFFs  (‘bull  neck’)  

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  106  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   107  

  • DIAGNOSIS  

    •  IsolaFon  of  the  organism  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   108  

  • TREATMENT  

    •  Starts  before  culture  confirmaFon  

    – Airway  maintenance  

    –   AnFtoxin  

    – AnFbioFcs  (erythromycin,  penicillin  G,  rifampin,  or  

    clindamycin)  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   109  

  • PREVENTION  

    •  Vaccine  

     

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   110  

  • COMPLICATIONS  

    •  Respiratory  obstrucFon  

    •  Heart  failure  

    •  Muscular  paralysis  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   111  

  • ACUTE  INFECTIONS  OF  THE  OROPHARYNX  

    •  Acute  tonsilliFs  •  Acute  non-‐specific  pharyngiFs  •  Acute  diphtheria  •  InfecFous  mononueclosis  •  Vincent’s  Angina  •  Scarlet  fever  •  Moniliasis  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   112  

  • INFECTIOUS  MONONUECLOSIS  

    •  Systemic  infecFon  caused  by  Epstein-‐Barr  

    Virus  (EBV)  

    •  SelecFvely  infects  B-‐lymphocytes  

    •  Clinical  disease  is  usually  seen  in  young  adults  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   113  

  • CLINICAL  MANIFESTATIONS  

    •  Clinical  triad  – Fever  – Lymphadenopathy  – PharyngiFs  and/or  tonsilliFs    

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   114  

  • INFECTIOUS  MONONUCLEOSIS  

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  115  

  • CLINICAL  MANIFESTATIONS  

    •  Clinical  triad  – Fever  – Lymphadenopathy  – PharyngiFs  and/or  tonsilliFs    

    •  Other  clinical  findings  – Splenomegaly  –  50%  – Hepatomegaly  –  10%  – Rash  –  5%  

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  116  

  • DIAGNOSIS  

    • CBC   w i t h   d i ff e r enFa l   ( a t y p i c a l  lymphocytes)  

    • DetecFon   of   heterophil   anFbodies   (Paul-‐  Bunnel  or  Monospot  test)  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   117  

  • TREATMENT  

    •  SymptomaFc  &  supporFve  treatment  

    •  Steroids  (severe  cases)  

    •  Avoid  ampicillin  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   118  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   119  

  • COMPLICATIONS  

    •  Autoimmune  hemolyFc  anemia  •  Cranial  nerve  palsies  •  EncephaliFs  •  HepaFFs  •  PericardiFs  •  Airway  obstrucFon  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   120  

  • VINCENT’S  ANGINA  

    q Subacute   infecFon   due   to   Spirochaeta  denFcolata  and  Vincent’s  fusiform  bacillus  

    q   Most  commonly   in  overcrowded  condiFons  “trench  fever”  

    q   Mild  local  and  systemic  symptoms  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   121  

  • VINCENT’S  ANGINA  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   122  

  • VINCENT’S  ANGINA  

    •  Subacute   infecFon   due   to   Spirochaeta  denFcolata  and  Vincent’s  fusiform  bacillus  

    •    Most   commonly   in   overcrowded   condiFons  “trench  fever”  

    •   Mild  local  and  systemic  symptoms  •  Management   is   with   penicillin   and   local   oral  hygiene  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   123  

  • SCARLET  FEVER  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   124  

  • SCARLET  FEVER  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   125  

  • SCARLET  FEVER  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   126  

  • FUNGAL  PHARYNGITIS  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   127  

  • CAUSES  

    •  Long  term  anFbioFcs  

    •  Immunosuppresion  (Leukopenia,  

    CorFcosteroid  therapy    etc)  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   128  

  • CANDIDIASIS  (MONILIASIS,  THRUSH)  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   129  

  • CANDIDIASIS  (MONILIASIS,  THRUSH)  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   130  

  • Treatment  

    •  NystaFn  

    •  Fluconazole  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   131  

  • CHRONIC  TONSILLAR  HYPERTOPHY  

  • CAUSES  

    •  Chronic  or  frequent  acute  infecFons  

    •  Idiopathic  (?exaggerated  immune  response)    

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   133  

  • PRESENTATION  

    •  Upper  airway  obstrucFon  

    – Mouth  breathing,  snoring  

    – Disturbed  sleep  and  apnea  

    •  Pulmonary  hypertension,  cor  pulmonale  and  

    heart  failure  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   134  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   135  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   136  

  • TREATMENT  

    •  Tonsillectomy  &  adenoidectomy  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   137  

  • CHRONIC  INFECTIONS  OF  THE  PHARYNX  

  • CHRONIC  NON-‐SPECIFIC  PHAYNGITIS  

    •  Primary  •  Secondary  – Sinonasal  disease  – Dental  infecFons  – Chest  infecFons  – Smoking  – Gastro  esophageal  reflux  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   139  

  • CLINICAL  FEATURES  

    •  Sore  throat  

    •  IrritaFon  

    •  Cough  

    •  O/E  

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  140  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   141  

  • TREATMENT  

    •  Treatment  of  the  cause  

    •  HumidificaFon  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   142  

  • CHRONIC  SPECIFIC  PHARYNGITIS  

    •  Tuberculosis  

    •  Syphilis  

    •  Lupus  vulgaris  

    •  Leprosy  

    •  Sarcoidosis  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   143  

  • CHRONIC  TONSILLITIS  

    •  Persistent  or  recurrent  sore  throat  

    •  Persistent  cervical  adeniFs  

    •  Halitosis  

    •  Congested  tonsils  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   144  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   145  

  • TREATMENT    

         

    Tonsillectomy  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   146  

  • TONSILLECTOMY  

  • INDICATIONS  

    •  ObstrucFng  tonsillar  enlargement  •  Suspected  malignancy  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   148  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   149  

  • INDICATIONS  

    •  Obstructed  tonsillar  enlargement  •  Suspected  malignancy  

    •  Repeated  a,acks  of  tonsilliFs  

    •  Chronic  tonsilliFs  •  One  a,ack  of  quinsy  

    •  Others  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   150  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   151  

  • CONTRAINDICATIONS  

    •  Bleeding  tendency  

    •  Recent  URTI  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   152  

  • COMPLICATIONS  

    •  Hemorrhage  – Primary  – ReacFonary  – Secondary  

    •  Respiratory  obstrucFon  •  Injury  to  near-‐by  structures  •  Pulmonary  and  distant  infecFons  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   153  

  • Primary  Hemorrhage    

    •  Bleeding  occurring  during  the  surgery  •  Causes  – Bleeding  tendency  – Acute  infecFons  – Aberrant  vessel  – Bad  technique  

    •  Management  – General  supporFve  measures  – Diathermy,  ligature  or  sFtches  – Packing    

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   154  

  • ReacFonary  Hemorrhage    

    •  Bleeding  occurring  within  the  first  24  hours  postoperaFve  period  

    •  Causes  –  Bleeding  tendency  –  Slipped  ligature  

    •  Diagnosis  –  Rising  pulse  &  dropping  blood  pressure  –  Ra,le  breathing  –  Blood  trickling  from  the  mouth  –  Frequent  swallowing  –  ExaminaFon    

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   155  

  • ReacFonary  Hemorrhage  

    •  Treatment  

    – General  supporFve  measures  

    – Take  the  paFent  back  to  OR  

    – Control  like  reacFonary  hemorrhage  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   156  

  • Secondary  hemorrhage      

    •  Occur  5-‐10  days  posoperaFvely  

    •  Due  to  infecFon  

    •  Treated  by  anFbioFcs  

    •  May  need  diathermy  or  packing  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   157  

  • Pharyngeal  (Zenker’s)  Pouch  

    A  mucosal  sac  protruding  through  Killian’s  dehiesence  

    4/7/14  11:06  PM  h,p://fac.ksu.edu.sa/aalroqi/home  158  

  • Pathogenesis  

    •  Most  probably  related  to  neuromuscular  

    incoordinaFon  

    – ?  Failure  of  relaxaFon  of  cricopharyngeus  

    – ?Early  closure  of  cricopharyngeus  

    – ?  Spasm  of  cricopharyngeus  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   159  

  • Clinical  Features  

    •  Dysphagia  

    •  RegurgitaFon  

    •  AspiraFon  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   160  

  • Diagnosis  •  Clinical  examinaFon  

    •  Barium  swallow  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   161  

  • 4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   162  

  • Diagnosis  

    •  Clinical  examinaFon  

    •  Barium  swallow  

    •  Endoscopy  

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   163  

  • Treatment  

    •  Excision    

    4/7/14  11:06  PM   h,p://fac.ksu.edu.sa/aalroqi/home   164  

  • THANK    YOU