5.01.542 medical necessity criteria for medication safety ... · o total daily opioid dose of more...

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PHARMACY BENEFIT COVERAGE GUIDELINE – 5.01.542 Medical Necessity Criteria for Medication Safety: Controlled Substances Utilization Service Program Effective Date: Jan. 1, 2020 Last Revised: Dec. 10, 2019 Replaces: N/A RELATED GUIDELINES / POLICIES: 5.01.529 Management of Opioid Therapy Select a hyperlink below to be directed to that section. COVERAGE GUIDELINES | CODING | RELATED INFORMATION | REFERENCES | HISTORY Clicking this icon returns you to the hyperlinks menu above. Introduction A controlled medication is a drug that is legal to use with a prescription but is highly regulated because of the potential for physical and mental dependence. Controlled medications are grouped into five classes by the Drug Enforcement Administration. The classes are based on a particular drug’s medical use, safety, and potential for abuse and/or dependence. While the vast majority of people who get prescriptions for controlled medications use them responsibly, there are some cases where prescription patterns point to overuse, misuse, or giving or selling the medication to others. In such cases, this policy describes the steps to ensure how a person can get their needed medication in safe quantities through a single provider. Note: The Introduction section is for your general knowledge and is not to be taken as policy coverage criteria. The rest of the policy uses specific words and concepts familiar to medical professionals. It is intended for providers. A provider can be a person, such as a doctor, nurse, psychologist, or dentist. A provider also can be a place where medical care is given, like a hospital, clinic, or lab. This policy informs them about when a service may be covered. Coverage Guidelines

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  • PHARMACY BENEFIT COVERAGE GUIDELINE – 5.01.542

    Medical Necessity Criteria for Medication Safety:

    Controlled Substances Utilization Service Program

    Effective Date: Jan. 1, 2020

    Last Revised: Dec. 10, 2019

    Replaces: N/A

    RELATED GUIDELINES / POLICIES:

    5.01.529 Management of Opioid Therapy

    Select a hyperlink below to be directed to that section.

    COVERAGE GUIDELINES | CODING | RELATED INFORMATION | REFERENCES | HISTORY

    ∞ Clicking this icon returns you to the hyperlinks menu above.

    Introduction

    A controlled medication is a drug that is legal to use with a prescription but is highly regulated

    because of the potential for physical and mental dependence. Controlled medications are

    grouped into five classes by the Drug Enforcement Administration. The classes are based on a

    particular drug’s medical use, safety, and potential for abuse and/or dependence. While the vast

    majority of people who get prescriptions for controlled medications use them responsibly, there

    are some cases where prescription patterns point to overuse, misuse, or giving or selling the

    medication to others. In such cases, this policy describes the steps to ensure how a person can

    get their needed medication in safe quantities through a single provider.

    Note: The Introduction section is for your general knowledge and is not to be taken as policy coverage criteria. The

    rest of the policy uses specific words and concepts familiar to medical professionals. It is intended for

    providers. A provider can be a person, such as a doctor, nurse, psychologist, or dentist. A provider also can

    be a place where medical care is given, like a hospital, clinic, or lab. This policy informs them about when a

    service may be covered.

    Coverage Guidelines

    https://www.lifewisewa.com/medicalpolicies/5.01.529.pdf

  • Page | 2 of 14 ∞

    Restriction Medical Necessity One-provider restriction One-Provider restriction may be considered medically

    necessary when there is evidence of excessive use, misuse,

    non-medical use, or diversion of one or more controlled

    substances by a member, and when one or more attempts to

    contact and work with the member to establish a plan for

    appropriate management of controlled substances via case

    management, chemical dependency treatment, enrollment in a

    pain management program, or self-imposed restriction to one

    prescriber, have failed.

    When restricted to one-provider, a single provider will be

    identified for coverage of prescriptions of all controlled

    substances for the member. The pharmacy claims system will

    be locked to prevent coverage of prescriptions of controlled

    medications unless they are prescribed by that provider.

    The existence of any one or more of the following criteria or

    behaviors may be used to identify individuals who may be

    engaged in the excessive use, misuse, non-medical use, or

    diversion of controlled substances:

    • Pattern of simultaneous or overlapping controlled substance

    prescribing involving multiple prescribers and/or pharmacies.

    This includes but is not limited to:

    o Multiple prescribers of same or similar controlled

    substances within overlapping timeframes;

    o Fills of controlled substances at multiple pharmacies within

    overlapping timeframes

    • Long-term, unusually high and escalating doses of controlled

    substances. This includes but is not limited to:

    o Total daily opioid dose of more than 120mg Morphine

    Equivalent Dose (MED), also known as Morphine Milligram

    Equivalent (MME)

    • Frequent early refill requests

    • Altered (any occurrence) or forged prescriptions

    • Multiple reports of misplaced, lost, or stolen medications or

    prescriptions

    • Increasing symptoms in spite of being on controlled substances

  • Page | 3 of 14 ∞

    Restriction Medical Necessity • Declining activity or functioning in spite of being prescribed

    controlled substances

    • Missing medical appointments except when a refill is expected

    or needed

    • Unwilling to try other non-controlled pharmacologic and non-

    pharmacologic treatments

    • Insistence on a specific controlled substance

    • Reports of, or appearing to be:

    o Intoxicated, somnolent, or sedated; or

    o Exhibiting withdrawal symptoms

    • Abnormal results on drug screening tests, such as opioids or

    cannabinoids when none should be present, or absence of

    opioid when they are being prescribed and should be present

    on testing

    • Unwillingness or inability to take medications as prescribed

    • Concurrent prescriptions for buprenorphine (Suboxone or

    Subutex) and an opioid

    • Unwillingness or failure to engage in evidence-based patient

    management methods that may include but are not limited to

    the following:

    o Pain management by a single provider, with all pain

    medications prescribed by that provider

    o Pain management agreement between the member and

    the provider outlining both the provider and member’s

    obligations surrounding the prescription, fulfillment, and

    management of controlled substances as well as a clear

    path of action when said contract is broken

    o Periodic drug screening tests

    o Attempts to taper controlled substance dosing as medically

    appropriate, using appropriate non-controlled drugs and

    nonpharmacologic treatments to optimize symptom

    management while minimizing controlled substance use

    Coding

  • Page | 4 of 14 ∞

    N/A

    Related Information

    Controlled substances are defined and categorized by the Drug Enforcement Administration

    (DEA) under classification C1 through C5 (or Schedule I to Schedule V). The categorization is

    based upon a substance’s medical use, potential for abuse, and safety or dependence liability.

    The medical policy encompasses all controlled substances; given all have potential for abuse; the

    data and evidence below are mainly focused on narcotics or opioids for the treatment of chronic

    noncancer pain (CNCP).

    There are numerous available treatment modalities for CNCP including pharmacologic and non-

    pharmacologic interventions. Among these, opioids, known for their strong analgesic properties,

    have gained popularity over the past two decades. Their use is established in the setting of

    acute, postoperative pain, cancer pain and pain at the end of life. In contrast, the role of opioids

    for managing CNCP is controversial, owing to the paucity of high-quality evidence

    demonstrating effectiveness and safety in this patient population. Existing data are limited by

    suboptimal study designs characterized by largely observational, non-comparative studies,

    short-term follow-up and significant withdrawal rates. Two Danish epidemiologic studies

    showed that in a region where opioids are prescribed liberally for pain, the patients receiving

    opioid analgesics reported worse pain, higher utilization of healthcare, and lower activity levels

    compared to matched controls. A population-based cohort study from the same authors

    showed the odds of recovery from chronic pain were four times higher in patients not using

    opioids, compared with those using opioids for pain management.23,27-29 While opioid analgesics

    are indeed effective in some patients, they may not be suitable for all. Therefore it is to the

    benefit of patients to constructively address the issue of over-prescribing, over-use, and misuse

    of opioid medications. Due to the substantial evidence of increasing morbidity and mortality

    associated with prescription opioid use, this medical policy which will guide appropriate use of

    controlled substances is necessary.

    Opioids produce both analgesia and euphoria. The mood altering action of opioids in addition

    to the physical dependence and addictive qualities of this class of drugs encourages abuse

    (nonmedical use). Opioid abuse and misuse occurs for a variety of reasons, including self-

    medication, use for reward, compulsive use because of addiction, and diversion for profit.27

    Individuals with chronic pain and co-occurring substance use disorders and/or mental health

    disorders, are at higher risk for misuse of prescribed opioids. The increasing use of opioid

  • Page | 5 of 14 ∞

    analgesics for treating chronic noncancer pain, and the introduction of high-dose, extended

    release oral tablet formulations of opioids with good bioavailability, has increased opportunities

    for the illicit use of prescription opioids. Such use has become a major societal problem,

    reaching epidemic proportions; it now exceeds the use of street narcotics in the United States. In

    April 2011, the White House unveiled a multi-agency plan aimed at reducing the “epidemic” of

    prescription drug abuse in the United States. The plan is a collaborative effort involving various

    agencies. According to the director of the White House Office of National Drug Control Policy

    (ONDCP) this plan “provides a national framework for reducing prescription drug abuse and the

    diversion of prescription drugs for recreational use.” Advocacy for prescribing opioids despite

    the lack of long-term effectiveness, unproven standards, and guidelines with conflicting

    recommendations, contributes to the epidemic of opioid abuse. Clinical decisions and practice

    recommendations must rely to a significant extent on practice experience and consensus rather

    than research evidence in assessing the treatment of acute and chronic noncancer pain.

    Evidence supporting long-term benefit of opioid analgesics for managing CNCP is lacking,

    owing to the predominantly observational and short-term nature of studies. Furthermore, data

    comparing various opioids and opioids to other analgesics or to nonpharmacologic modalities

    are also lacking. The harms from prescription opioids to patients and others are substantial and

    increasingly recognized. When opioids are used, initial risk assessment, careful dose titration and

    monitoring including functional outcomes, while educating patients is key. It is also important to

    recognize patients at highest risk of adverse events – those receiving high opioid doses and

    from multiple providers.

    Various guidelines which have been published all agree that prevention of controlled substance

    abuse is key. For providers, the ability to identify patients who are most “at-risk” for developing

    prescription drug abuse prior to initiation of opioids is critical. Screening patients to determine

    their risk of drug abuse prior to beginning opioid therapy is considered standard of practice.27

    Several risk factors have been described and include sociodemographic factors, pain and drug-

    related factors, genetics and environment, psychosocial and family history, psychopathology,

    and alcohol and substance use disorders. It is suggested that the risk of prescription drug abuse

    is greatest when risk factors in 3 categories occur in the same individual. In the absence of

    psychosocial comorbidities and genetic predisposition, pain patients on stable doses of opioids

    in a controlled setting are unlikely to abuse opioids or develop addiction. On the other hand,

    patients with a personal or family history of substance abuse, and psychosocial comorbidity, are

    at increased risk, especially if treatment with opioids is not carefully structured and monitored

    (Ballantyne). Patients who are undergoing chronic opioid therapy for pain have been shown to

    have significantly higher Screener and Opioid Assessment for Patients with Pain (SOAPP),

    Current Opioid Misuse Measure (COMM), and drug misuse index (DMI) scores (p

  • Page | 6 of 14 ∞

    evidence of doctor-shopping were significantly more likely to have a previous history of

    overdose, or a history of substance abuse.14 These data suggest that both patients and providers

    may benefit from other treatment options before beginning opioid therapy for pain such as

    exercise and cognitive behavioral therapy for chronic management.

    Indicators of Potential Excessive Use, Misuse, Non-Medical Use, or

    Diversion of Controlled Substance

    When treatment with controlled medications has already been initiated, identification of

    indicators of potential excessive use, misuse, non-medical use, or diversion becomes critical to

    preventing or intervening in cases of abuse, addiction, or serious adverse events. Clinical

    experience and studies have identified a number of factors that indicate potential excessive use,

    misuse, non-medical use, or diversion. There is no factor that is absolutely indicative of excessive

    use, misuse, non-medical use; identification of one or more factors requires individual patient

    evaluation to differentiate between inappropriate use and possible appropriate use given a

    patient’s unique clinical circumstances.23,38

    The most common indicators of potential excessive use, misuse, non-medical use, or diversion

    are doctor shopping, and high or escalating doses of opioids. These two are widely used

    criterion to identify people who may be engaged in non-medical use of controlled substances.

    Cantrell et al.35 use the following criteria for identification of ‘doctor shopping’: 2 or more

    prescribers within 30 days, greater than 4 during 1 year, and greater than 5 during 1 year.14,15,34

    Pradel et al.19 defined doctor shopping as the amount of drug obtained through doctor

    shopping compared with the amount intended to be prescribed. The use of “pill mills,” in which

    a prescriber provides ready access to prescriptions or pills, can also be considered a form of

    doctor shopping.35

    Doctor shopping is directly associated with the incidence of deaths from opioids. Hall et al.14

    reviewed characteristics of decedents who died of prescription drugs in West Virginia and

    reported that opioid analgesics accounted for 93% of deaths. The authors determined the

    prescription history of the drug associated with each fatality. Patients who had received

    controlled drugs from 5 or more prescribers in the year before death were defined as engaging

    in “doctor shopping,” whereas those whose death was not associated with a valid prescription

    were considered to have obtained their drugs through “diversion.” Doctor shopping was

    associated with 63 (21%) of the fatalities and diversion was associated with 186 (63%) of the

    fatalities. Of the 295 total decedents, 279 (95%) had at least 1 indicator of substance abuse, and

    those differed according to whether the drug was obtained through diversion or doctor

  • Page | 7 of 14 ∞

    shopping. A report from the CDC reported a rise in prescription opioid-related deaths of 68%

    between 1999 and 2004. The CDC also studied prescription drug overdoses and found that 10%

    of patients seeing multiple doctors and typically involved in drug diversion accounted for 40%

    of the overdoses (see figure below). This illustrates that patients are more likely to overdose if

    they are seeing multiple doctors or if they are on a high dose of controlled drug.

    High or escalating doses of opioids are also associated with a greater incidence of adverse

    outcomes, including opioid-related fatal overdoses. In a study24 of 9,940 adults receiving long-

    term opioid therapy for chronic noncancer pain, those who received 100mg/day or more of

    morphine equivalent had an 8.9 fold increase in overdose risk (95% CI 4.0-19.7). Although there

    is not uniform agreement on what constitutes an excessive dose of opioid, there is a general

    consensus that doses above 200 mg Morphine Equivalent Dose (MED) total daily dose should be

    considered to be excessive.27

    In addition to doctor shopping and high or escalating doses, other factors that have been

    identified as indicators of potential excessive use, misuse, non-medical use, or diversion include

    multiple prescribers of controlled substances, use of multiple pharmacies to fill controlled

    substances prescriptions, the number of controlled prescriptions in defined time periods, and

    overlapping or concomitant controlled substances prescriptions. Manchikanti et al.24 noted that

    available national data overwhelmingly suggest that the increased supply of opioids, high

    medical users, doctor shoppers, and patients with multiple comorbid factors contribute to the

    majority of fatalities. They observed that on average, patients were exposed to 2 different

    opioids and had 3 different opioid prescribers. Braker et al.39 found that a retrospective review of

  • Page | 8 of 14 ∞

    payer opioid prescription data and patient charts from a rural family medicine group identified

    patients with 3 or more prescriptions (average 8.4; standard deviation = 5.5; range 3-28) from 2

    or more providers (average 3.7; SD = 1.8, range 2-10) over a 6-month period. Concurrent use of

    nonopioid analgesics, escalating opioid dosage, and number of providers were the best

    predictors for adverse events. Findings from other studies are summarized in the table below.

    Author Criteria which identified potential abuse

    Gonzalez et al.26 Members who received opioid prescriptions from 3 or more prescribers at 3 or more pharmacies in

    a 3-month identification period

    Sehgal et al.27 Patients with 3 or more prescriptions from 2 or more providers over a 6-month period; concurrent

    use of nonopioid analgesics; escalating opioid dosage; and number of providers

    Cepeda et al.36 Overlapping or concomitant prescriptions defined as at least 1 day of overlapping dispensing of

    prescriptions written by two or more different prescribers at any time during an 18-month period;

    Authors concluded that having two or more overlapping prescriptions written by different

    prescribers and filled at 3 or more pharmacies differentiates opioids from diuretics and likely

    constitutes shopping behavior.

    Dunn et al.37 3 or more prescriptions for opioid analgesics in the first 90 days of the episode

    Parente et al.2 developed a claims-based method to identify patients who may be misusing

    controlled substances and prescribers who may be providing pharmacologic management that

    warrants evaluation. They drew data from health insurance claims and used an 11-member

    multidisciplinary expert panel to define criteria for identifying controlled substance patterns of

    utilization requiring evaluation. The goal in defining the criteria was to have this be widely

    applicable to claims databases to identify possible abuse or diversion of controlled substances

    by patients or mismanagement by prescribers. The table below outlines the ten patterns that

    were most positively associated with identification of a misuse case.

  • Page | 9 of 14 ∞

    Additional factors that have been identified as potential indicators of excessive use, misuse, non-

    medical use, or diversion include1 frequent early refill requests; altered or forged prescriptions;

    multiple reports of misplaced, lost, or stolen medications or prescriptions; insistence on a

    specific controlled substance; missing medical appointments except when a controlled

    substance refill is expected or needed; increasing symptoms in spite of being on controlled

    substances; declining activity or functioning in spite of being on controlled substances; refusal

    to try other non-controlled pharmacologic and non-pharmacologic treatments; reports of or

    appearing to be intoxicated, somnolent, sedated, or exhibiting withdrawal symptoms; positive

    results for controlled medications on drug screening tests when none have been prescribed;

    absence of positive results for controlled medications on drug screening tests when they are

    being prescribed; concurrent prescriptions for buprenorphine (Suboxone or Subutex) and an

    opioid; unwillingness to take medications as prescribed; and unwillingness or failure to engage

    in evidence-based patient management methods.

    Although most published studies focus on steps that providers can take to identify patients who

    are displaying evidence of possible excessive use, misuse, non-medical use, or diversion, a small

    but growing literature is establishing evidence of actions that can be taken by health insurance

    companies and managed care companies. For example, Gonzalez et al26 studied the impact of a

    care coordination intervention by a managed care organization after identification of potential

    opioid misuse. Using their database of prescription claims, the organization identified members

    who filled controlled opioid medications prescribed by three or more providers and filled at

  • Page | 10 of 14 ∞

    three or more pharmacies in a three-month period. Half of these members were randomized to

    an intervention arm in which a letter was sent quarterly to the prescriber explaining their patient

    was receiving multiple opioid prescriptions filled at multiple locations. They were also sent a

    clinical medication report detailing each opioid prescription that was filled by their patient in the

    past three months, at which pharmacies, and who the other prescribers were. The prescriber was

    encouraged to contact the other prescribers listed in an effort to coordinate care. For members

    in the control group, generic letters were sent to the prescriber discussing the importance of

    opioid management, but no details or identifying information were given. The members in the

    intervention group showed a 24% greater reduction in number of prescribers, 16% greater

    reduction in the number of pharmacies used, and a 15% greater reduction in number of

    controlled opioid prescriptions compared to the control group. The authors concluded that

    managed care organizations have the opportunity to identify potential opioid misuse and

    implement care coordination interventions. Additionally the study revealed patients receiving

    opioid prescriptions from multiple prescribers and pharmacies during short time intervals is

    evidence of uncoordinated pain management and suggests misuse of opioid medications.

    Although dependence or addiction to opioid medications cannot be diagnosed by analysis of

    prescription claims alone, prescription claims may be used as a tool to guide future prescribing

    and to pinpoint factors associated with the uncoordinated care of a member.

    One Prescriber Restrictions

    Limiting the prescription and management of controlled substances to a single prescriber has

    become standard of care for patients receiving chronic treatment for non-cancer disorders. As

    noted in the previous section, evidence-based studies have documented a direct relationship

    between the number of prescribers of opioids for a patient and the severity of adverse effects

    including opioid-related deaths.24,39 Conversely, limiting opioid prescription and management to

    a single prescriber significantly reduces the occurrence of severe adverse effects and fatal

    outcomes associated with treatment with opioids.40

    Systematic reviews of evidence-based treatment guidelines for pain management demonstrate

    almost universal agreement that controlled medications should be prescribed and managed by

    a single prescribing physician, or a single treatment team for patients who are managed by a

    clinic team.41 42 When a patient’s health care is being managed by multiple provides, which is

    common, all providers should agree on a single designated prescriber for controlled pain

    medications.41

    Systematic reviews of evidence-based treatment guidelines have also established the usefulness

    of patient-provider agreements, also known as patient contracts, when controlled pain

  • Page | 11 of 14 ∞

    medications are utilized for the management of chronic non-cancer pain.41 Reviews of the

    specific components of patient-provider agreements have consistently identified the

    identification and utilization of a single prescriber of controlled medications as a key component

    of such agreements.23,41

    A number of prominent provider organizations, concerned about escalating numbers and doses

    of opioid prescriptions, have taken steps to limit and prevent excessive use, misuse, non-medical

    use, diversion, and adverse outcomes. Group Health Cooperative in Washington state developed

    and implemented a comprehensive guideline for chronic opioid therapy for patients with

    chronic non-cancer pain. Compliance with the guideline is mandatory for all of Group Health’s

    clinicians. Among the stipulations in the guideline is the requirement that for patients taking

    opioids for chronic non-cancer pain, each patient’s opioids must be prescribed and managed by

    a single physician.43,44

    Government agencies have also become increasingly concerned about escalating use of

    controlled prescription medications, particularly opioids due to the alarming increase in the

    number of deaths from accidental overdoses (BMJ). Various state and Federal agencies have

    devised programs targeting excessive use of opioids, including prescription monitoring

    programs that allow prescribing clinicians to access databases listing all controlled medications

    prescribed to patients. The state of Washington has also issued mandatory rules for the

    management of chronic non-cancer pain. Based on the best available evidence, the rules

    stipulate, among other provisions, that chronic non-cancer pain patients receive all chronic pain

    management prescriptions from one physician.45

    Benefit Application

    This policy is managed through the Pharmacy benefit.

    References

    1. Wunsch, M, Boyd, C, McMaster M, “Nonmedical Use of Prescription Medications” in Ries, R, Fiellin, D, Miler, S, Saltz, R, ed.

    Principles of Addiction Medicine, 4th edition, Chapter 33, pp 453-467; Lippincott Williams and Wilkins; 2009.

    2. Parente, S, Kim, S, Finch, M, et al. Identifying Controlled Substance Patterns of Utilization Requiring Evaluation Using

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    3. Federation of State Medical Boards. Model Policy for the Use of Controlled Substances for the Treatment of Pain. May 2004.

    4. Drug Utilization Review. Academy of Managed Care Pharmacy, Nov. 2009.

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    5. SAMHSA. Results from the 2006 National Survey on Drug Use and Health: national findings. Rockville, MD: Substance Abuse

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    19. Pradel V, Frauger E, Thirion X, et al. Impact of a prescription monitoring program on doctor-shopping for high dosage

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    33. Savage S, Covington EC, Gilson AM, Gourlay D, Heit HA and Hunt JB. Definitions related to the use of opioids for the treatment

    of pain: consensus statement of the American Academy of Pain Medicine, the American Pain Society, and the American Society

    of Addiction Medicine. Consensus revision adopted April 2004.

    34. Wilsey BL, Fishman SM, Gilson AM, et al. Profiling multiple providers prescribing of opioids, benzodiazepines, stimulants, and

    anorectics. Drug Alcohol Dependence. 2010;112:99-106.

    35. Cantrill SV, Brown MD, Carlisle RJ, Delaney KA, et al. Clinical Policy: Critical Issues in the prescribing of opioids for adult patients

    in the emergency department. Ann Emerge d. 2012;60:499-525.

    36. Cepeda MS, Fifd D, Chow W, Mastrogiovanni G and Henderson SC. Assessing Opioid Shopping Behaviour: A Large Cohort

    Study from a Medication Dispensing Database in the US. Drug Saf 2012: 35(4):325-334.

    37. Dunn KM, Saunders KW, Rutter CM, Banta-Green CJ, O Merril J, Sullivan MD et al. Overdose and prescribed opioids:

    Associations among chronic non-cancer pain patients. Ann Intern Med. 2010 January 19; 152(2):85-92.

    38. Smith, HS, Argoff, L, “Chronic Opioid Therapy in Pain Management,” in Ebert, M, Keins, RD, Behavioral and

    Psychopharmacologic Pain Management, pp 142-164; Cambridge University Press; 2011.

    39. Braker LS, Reese LA, Card RO, and Van Howe RS. Screening for potential prescription misuse in a Michigan Medicaid

    population. Family Medicine. 2009; 41 (10): 729-734.

    40. Franklin GM. Opioids: A Public Health Emergency. National Summit on Opioid Safety. Group Health Cooperative. Seattle, WA,

    November 1, 2011.

    41. Hughes MA, Biggs JJ, Thiese MS, et al. Recommended opioid prescribing practices for use in chronic non-malignant pain: a

    systematic review of treatment guidelines. Journal of Managed Care Medicine. 2010; 14 (3): 52-58.

    42. Von Korff M, Kolodny A, Deyo RA, and Chou R. Long term opioid therapy reconsidered. Annals of Internal Medicine. 2011; 155

    (5): 325-328.

    43. McCarthy M. Containing the opioid overdose epidemic. BMJ. 2012; 345; e8340.

    44. Group Health Cooperative. Chronic Opioid Therapy Safety Guidelines for Patients with Chronic Non-Cancer Pain. 2010-2012.

    45. Washington Administrative Code 246-919-856. Pain Management Rules. Washington State Department of Health-Medical

    Quality Assurance Commission. Effective January 2, 2012.

  • Page | 14 of 14 ∞

    History

    Date Comments 10/09/12 New policy added to Prescription Drug section. Policy approved with 90-day provide

    notification hold. The policy is effective February 11, 2013.

    01/22/13 Policy effective date delayed and is now April 1, 2013.

    03/11/13 Replace policy. Policy updated within the Policy Guidelines, clarifying criteria added,

    removed and rearranged; Description section removed; Rationale section significantly

    updated; references added, removed, renumbered and updated. Policy effective date

    remains April 1, 2013.

    07/08/13 Minor Update – Clarification was added to the policy that it is managed through the

    member’s pharmacy benefit; this is now listed in the header and within the coding

    section.

    12/08/14 Annual Review. Converted to Benefit Coverage Guideline template. No change in

    policy statement.

    09/08/15 Annual Review. No change in coverage statements.

    11/01/16 Annual Review, approved October 11, 2016. Updated Coverage Guideline sentence.

    09/01/17 Annual Review, approved August 22, 2017. No changes to coverage guidelines.

    11/01/18 Annual Review, approved October 26, 2018. No changes to coverage guidelines.

    01/01/20 Annual Review, approved December 10, 2019. No changes to coverage guidelines.

    Disclaimer: This medical policy is a guide in evaluating the medical necessity of a particular service or treatment. The

    Company adopts policies after careful review of published peer-reviewed scientific literature, national guidelines and

    local standards of practice. Since medical technology is constantly changing, the Company reserves the right to review

    and update policies as appropriate. Member contracts differ in their benefits. Always consult the member benefit

    booklet or contact a member service representative to determine coverage for a specific medical service or supply.

    CPT codes, descriptions and materials are copyrighted by the American Medical Association (AMA). ©2020 Premera

    All Rights Reserved.

    Scope: Medical policies are systematically developed guidelines that serve as a resource for Company staff when

    determining coverage for specific medical procedures, drugs or devices. Coverage for medical services is subject to

    the limits and conditions of the member benefit plan. Members and their providers should consult the member

    benefit booklet or contact a customer service representative to determine whether there are any benefit limitations

    applicable to this service or supply. This medical policy does not apply to Medicare Advantage.

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    Health Plan of Washington. Maaaring may mga mahalagang petsa dito sa Washington ਵਲ ਤੁ ਜ ਅਤੇ ਅਰਜੀ ਬਾਰੇ ਮਹਤਵਪੂ ੋ ਸਕਦੀ ਹਾਡੀ ਕਵਰੇ ੱ ਰਨ ਜਾਣਕਾਰੀ ਹ

    ពទ

    paunawa. Maaring mangailangan ka na magsagawa ng hakbang sa ilang ਹੈ ੋ ਿਜਸ ਜਵਚ ਖਾਸ ਤਾਰੀਖਾ ਹੋ ਂ ਹਨ. ਜੇ ੁ ੇ ੱ ਖਣੀ ਹੋ ੇ mga itinakdang panahon upang mapanatili ang iyong pagsakop sa . ਇਸ ਨ ਸਕਦੀਆ ਕਰ ਤਸੀ ਜਸਹਤ ਕਵਰਜ ਿਰ ਵ ਜਾ ਓਸ ਦੀ ਲਾਗਤ ਜਿਵੱਚ ਮਦਦ ਦੇ ੱ ੁ ੋ ਤਾਂ ਤੁ ੰ ੂ ਤਮ ਤਾਰੀਖ਼ ਤ ਪਿਹਲਾਂ ਕੁ kalusugan o tulong na walang gastos. May karapatan ka na makakuha ng ਇਛਕ ਹ ਹਾਨ ੱ ਝ ਖਾਸ

    ganitong impormasyon at tulong sa iyong wika ng walang gastos. Tumawag ਕਦਮ ਚੁਕਣ ਦੀ ਲੜ ਹੋ ਸਕਦੀ ਹ ੈ,ਤੁ ੰ ੂ ਮੁ ੱ ਚ ਤੇ ੱ ਚ ਜਾਣਕਾਰੀ ਅਤੇ ੱ ੋ ਹਾਨ ਫ਼ਤ ਿਵ ਆਪਣੀ ਭਾਸ਼ਾ ਿਵ ਮਦਦ sa 800-592-6804 (TTY: 800-842-5357). ਪ੍ਰ ੈਾਪਤ ਕਰਨ ਦਾ ਅਿਧਕਾਰ ਹ ,ਕਾਲ 800-592-6804 (TTY: 800-842-5357).

    ਪੰ

    Tagalog (Tagalog): Ang Paunawa na ito ay naglalaman ng mahalagang impormasyon. Ang

    ไทย (Thai): ประกาศน ้ีมีข้อมลูสําคญั ประกาศน ้ีอาจมีข้อมลูที่สําคญัเกี่ยวกบัการการสมคัรหรือขอบเขตประกนั

    (Farsi): فارسی فرم بارهدر ھمم اطالعات حاوی است ممکن يهمالعا اين . ميباشد ھمم اطالعات یوحا يهمالعا اين

    สขุภาพของคณุผ่าน LifeWise Health Plan of Washington และอาจมีกําหนดการในประกาศ طريق از ماش ای مهبي وششپ يا و تقاضا LifeWise Health Plan of Washington به .باشدี น جهتو يهمالعا اين در ھمم ھای خيتار يا تان بيمه وششپ حقظ برای است کنمم ماش . يدماين کمک คณุอาจจะต้องดําเนินการภายในกําหนดระยะเวลาที่แน่นอนเพื่อจะรักษาการประกนัสขุภาพของคณุ

    اجتياح صیاخ کارھای امانج برای صیمشخ ھای خيتار به تان، انیمدر ھای زينهھ پرداخت درหรือการช่วยเหลือที่มีค่าใช้จ่าย คณุมีสิทธิที่จะได้รับข้อมลูและความช่วยเหลือน ้ีในภาษาของคณุโดยไม่ม ีباشيد داشته . رايگان ورط به ودخ انزب به را مکک و اطالعات اين که داريد را اين حق ماش

    (ค่าใช้จ่าย โทร 800-592-6804 (TTY: 800-842-5357 مارهش با اطالعات سبک برای . نماييد دريافت 800-592-6804 . اييد نم برقرار استم ) 5357-842-800 مارهباش اس تم TTY کاربران(

    Polskie (Polish): To ogłoszenie może zawierać ważne informacje. To ogłoszenie może zawierać ważne informacje odnośnie Państwa wniosku lub zakresu świadczeń poprzez LifeWise Health Plan of Washington. Prosimy zwrócic uwagę na kluczowe daty, które mogą być zawarte w tym ogłoszeniu aby nie przekroczyć terminów w przypadku utrzymania polisy ubezpieczeniowej lub pomocy związanej z kosztami. Macie Państwo prawo do bezpłatnej informacji we własnym języku. Zadzwońcie pod 800-592-6804 (TTY: 800-842-5357).

    Português (Portuguese): Este aviso contém informações importantes. Este aviso poderá conter informações importantes a respeito de sua aplicação ou cobertura por meio do LifeWise Health Plan of Washington. Poderão existir datas importantes neste aviso. Talvez seja necessário que você tome providências dentro de determinados prazos para manter sua cobertura de saúde ou ajuda de custos. Você tem o direito de obter esta informação e ajuda em seu idioma e sem custos. Ligue para 800-592-6804 (TTY: 800-842-5357).

    Український (Ukrainian): Це повідомлення містить важливу інформацію. Це повідомлення може містити важливу інформацію про Ваше звернення щодо страхувального покриття через LifeWise Health Plan of Washington. Зверніть увагу на ключові дати, які можуть бути вказані у цьому повідомленні. Існує імовірність того, що Вам треба буде здійснити певні кроки у конкретні кінцеві строки для того, щоб зберегти Ваше медичне страхування або отримати фінансову допомогу. У Вас є право на отримання цієї інформації та допомоги безкоштовно на Вашій рідній мові. Дзвоніть за номером телефону 800-592-6804 (TTY: 800-842-5357).

    Tiếng Việt (Vietnamese): Thông báo này cung cấp thông tin quan trọng. Thông báo này có thông tin quan trọng về đơn xin tham gia hoặc hợp đồng bảo hiểm của quý vị qua chương trình LifeWise Health Plan of Washington. Xin xem ngày quan trọng trong thông báo này. Quý vị có thể phải thực hiện theo thông báo đúng trong thời hạn để duy trì bảo hiểm sức khỏe hoặc được trợ giúp thêm về chi phí. Quý vị có quyền được biết thông tin này và được trợ giúp bằng ngôn ngữ của mình miễn phí. Xin gọi số 800-592-6804 (TTY: 800-842-5357).