PATENT ABSTRACTS 473

5096820 5096837

P R O C E S S F O R M A N U F A C T U R I N G X Y L I T O L

A N D X Y L I T O L - R I C H P R O D U C T S

I M M U N O C H R O M A T O G R A P H I C A S S A Y A N D M E T H O D O F U S I N G

S A M E

Jean-Bernard Leleu, Pierrick Duflot, Jean- Jacques Caboche, Lestrem, France assigned to Roquette Freres

Process for manufacturing xylitol and xylitol- rich products, characterized in that it consists of: enzymatically isomerizing at M! D-xylulose syrup into syrup containing D-xylose and D- xylulose then, without extracting the xylose, catalytically hydrogenating this syrup at M2, resulting thus in a xylitol-rich syrup, said xylitol- rich syrup being either dehydrated, or subjected to chromatographic processing or to a treatment of extraction by crystallization at M3.

Eugene Fan, Dou-Mei Wang, Fon-Chiu M Chen, Gregg L Wilson, Michael Milner, Ching Huang assigned to Pacific Biotech Inc

The invention disclosed herein relates to the field of one-step assays and latex agglutination tests ( LAT), and provides an improved method of pre- paring and using a one-step immunoassay, as well as improved methods of preparing coated latex particles for use in diagnostic assays, and especially, immunochromatographic assays.

5098825

5096833

M E T H O D A N D D E V I C E F O R D E T E R M I N I N G P R O T E I N U S I N G C A R R I E R M A T R I X C O M P O S E D

O F U R E T H A N E , W A T E R I N S O U B L E I N O R G A N I C

C O M P O U N D A N D I N S O L U B L E O R G A N I C C O M P O U N D A N D M E T H O D O F M A K I N G T H E

D E V I C E

Arthur L Y Lau, James H Pendergrass, Carrie A Ritucci assigned to Miles Inc

P R O B E C O N T A I N I N G A M O D I F I E D N U C L E I C A C I D

R E C O G N I Z A B L E B Y S P E C I F I C A N T I B O D I E S A N D U S E O F T H I S

P R O B E T O D E T E C T A N D C H A R A C T E R I Z E A

H O M O L O G O U S D N A S E Q U E N C E

Paul Tchen, Phili Kourilsky, Marc Leng, Anne B Cami, Nanterre, France assigned to Institut Pasteur

A method and kit for detecting a predetermined nucleotide sequence in a specimen using a nucleic acid probe modified with N-2- acetylaminofluorene (AAF).

A test device and method of determining the pre- sence and concentration of proteins in a test sam- ple are disclosed. The test device includes a test pad comprising a new and improved carrier matrix incorporating an indicator reagent com- position capable of interacting with proteins to produce a detectable or measurable response. The new and improved carrier matrix of the test pad comprises a film, membrane or layer of a polymerized urethane-based compound, a water insoluble inorganic compound and an insoluble organic compound. The carrier matrix provides improved color resolution and increased sensitivity to proteins in dry phase test strip assays, thereby achieving an accurate and trust- worthy protein assay of a liquid test sample, such as urine, having a protein concentration as low as about 5 mg/dL. Also disclosed is a method of making the test device.

5098830

V E R Y R A P I D D E T E C T I O N O F F U N G A L I N F E C T I O N S

David Bar-or, Clive Solomons assigned to Dia- gnostic Markers Inc

A method for the detection o fa fungal infection within 1-2 hours comprises the steps of: (a) con- tacting a sample suspected of containing a peroxidase-containing fungus with a mixture which comprises (i) a peroxide from hydrogen peroxide and addition compounds thereof con- taining latent hydrogen peroxide; (ii) a scavenger to remove heavy metals which may potentially