5 ~ 6 2 ~

PATENT ABSTRACTS

P H O S P H I N O T H R I C I N R E S I S T A N C E G E N E , A N D ITS

U S E

Eckhar Strauch, Walter Arnold, Renate Alijah, Wolfgang Wohlleben, Alfred Puhler, Peter F.ekes, Gunter Donn, Eugen Uhlmann, Friedrich Hein, Friedrich Wengenmayer, Bi- elefeld, Federal Republic Of Germany assigned to Hoechst Aktiengesellschaft

The phosphinothricin (PTC)-resistance gene isolated from the genome of Streptomyces viridochromogenes DSM 40736 is, after adapta- tion to the codon usage in plants, synthesized and incorporated into gene structures which make plants resistant to PTC after expression therein.

5277780

E L E C T R O P H O R E S I S G E L M I G R A T I O N A P P A R A T U S

Hidek Kambara, Hachiouji, Japan assigned to Hitachi Ltd

A gel capillary electrophoresis apparatus has gel capillaries (2) filled with gel (2a) that are fixed at both ends thereof on an upper plate 5 and a lower plate (6). The gel capillaries (2) are ar- ranged coarse on the upper plate (5) for sample injection and dense on the lower plate (6) for fluorescence detection. The apparatus is made easy in the sample injection and high in the fluorescence detection efficiency so that throughput of analysis of DNA and the like can be increased, and is available for three- dimensional electrophoresis.

559

thuringiensis microbe of the invention is referred to as B.t. PS50C. The spores or crystals of this microbe, or mutants thereof, are useful to con- trol coleopteran pests in various environments. The novel gene of the invention can be used to transform various hosts wherein the novel toxic protein can be expressed.

5278042

M E T H O D F O R D E T E C T I N G I N H I B I T O R S O F T A T P R O T E I N

Flossie Wong-Staal, Jay Rappaport, James R Rusche assigned to The United States of America as represented by the Department of Health & Human Services

A method for evaluating the inhibitory effect of a substance on tat-protein TAR RNA binding is described. A test system for determining the as- sociation of tat-protein with TAR RNA is also included within the scope of the invention.

5278049

R E C O M B I N A N T M O L E C U L E E N C O D I N G H U M A N P R O T E A S E

N E X I N

Joffre B Baker, Randy W Scott assigned to In- cyte Pharmaceuticals Inc

DNA segments encoding two slightly different protease nexin I forms (PN-I alpha and PN-I beta) are cloned and expressed to provide prac- tical quantities of PN-I for diagnostic and therapeutic use. PN-I is a serine protease in- hibitor useful in controlling conditions mediated by proteolytic activity.

5 ~ 7 ~ 5

C O L E O P T E R A N - A C T I V E B A C I L L U S T H U R I N G I E N S I S

I S O L A T E

Luis Foncerrada, August J Sick, Jewel M Payne assigned to Mycogen Corporation

The subject invention concerns a novel microbe and gene encoding a novel toxin protein with ac- tivity against insect pests of the order Coleop- tera. Pests in the order Coleoptera do heavy damage to crops, e.g., corn. The novel Bacillus

5 ~ 8 ~ 0

M E T H O D T O I M P R O V E T H E E F F I C I E N C Y O F P R O C E S S I N G A N D S E C R E T I O N O F F O R E I G N

G E N E S IN I N S E C T S Y S T E M S

Max D Summers assigned to The Texas A&M University System

The engineering of foreign vertebrate gene con- structs by recombinant DNA techniques for the more efficient processing and secretion of fore- ign genes in insect systems is done by replacing