6th Annual Neuromuscular ColloquiumFriday, May 20, 2016Balboa Bay Resort 1221 W. Coast Highway Newport Beach, CA 92663

This activity has been approved for AMA PRA Category 1 Credits™.

NONPROFIT ORGU.S. POSTAGE

PAIDSanta Ana, CA

Permit No. 1106Business Development Office333 City Blvd. West, Suite 200Orange, CA 92868

Target Audience

Physicians and all other healthcare providers working in the fields of neurology, neuromuscular disorders, and clinical neurophysiology.

Course Description

The 2016 Neuromuscular Colloquium provides an academic forum for regional and national physicians who specialize entirely, or to a significant degree, in neuromuscular medicine. This activity is designed to encourage an atmosphere of collaboration and interaction between the various neuromuscular specialists in the region. It is a forum to discuss the latest topics and advances in neuromuscular medicine and review interesting and challenging cases, with several live patient presentations. Such activities are likely to improve patient care because they promote closer research collaboration and the development of new research projects between the various groups and institutions.

Learning Objective

After completing the learning activity, the participant should be able to:

• Describe current diagnostic and management strategies in chronic inflammatory demyelinating polyneuropathies, and recognize atypical manifestations especially in diabetic patients.

• Identify best outcome measures when assessing clinical and research outcomes in myasthenia gravis using current treatment and management strategies.

• Identify different patterns of clinical involvement in patients with neuromuscular disorders; recognize systemic and medical complications in these patients; understand current guidelines for management of patients with muscular dystrophies, Pompe disease, spinal muscular atrophy and amyloidosis.

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6th Annual Neuromuscular Colloquium

Waterfront Views

MapBalboa Bay Resort

Grand Ball Room 1221 W. Coast Highway Newport Beach, CA 92663

Guest Room Reservations* Conference rate while availability lasts: $269.00 standard king. Resorts, fees, tax and parking are additional. Book early.

Go to www.balboabayresort.com, type in your check-in and check-out date, then click Book now.

On the next page, type 1605UCINEU into the Group Code field on the bottom left to access the group rate, then click Check Availability.

Alternatively, you may call 888-894-2788 and refer to room block as UCI Neuromuscular Symposium.

Keynote Speaker

Vera Bril, MD, FRCP(C)Dr. Vera Bril is a professor of medicine (neurology) at the University of Toronto, medical director of the Krembil Neurosciences Program at University Health Network, director of neurology at University Health Network and Mount Sinai Hospital and the Krembil Family Chair in neurology. She has particular expertise in the diagnosis and management of patients with complex neuromuscular disorders. Her research interests have centered on the diagnosis and evidence-based treatment of myasthenia gravis, inflammatory polyneuropathies and diabetic sensorimotor polyneuropathy.

Mathilda Karel Spak Speaker

Michael Benatar, MDDr. Benatar is a professor of neurology, and epidemiology and public health at the University of Miami, Miller School of Medicine. He is also the chief of the Neuromuscular Division and the first incumbent of the Walter Bradley Chair in ALS Research. His primary clinical interest is in amyotrophic lateral sclerosis (ALS), myasthenia gravis and electromyography. His primary research focus is on ALS (including clinical trials, genetics and biomarker development), and myasthenia gravis.

Course Chairs

Tahseen Mozaffar, MDProfessor of Neurology Vice Chair for Education, Neurology UC Irvine Health

Annabel K. Wang, MDAssociate Professor of Neurology, UC Irvine Health Director, Neuromuscular Section, VA Long Beach, VA Long Beach Healthcare System

Namita A. Goyal, MDAssociate Professor of Neurology Director, Neuromuscular Medicine Fellowship Director, Neuromuscular Diagnostic Laboratory UC Irvine Health

Faculty

Said R. Beydoun, MDProfessor of Neurology Director, Neuromuscular Program Keck School of Medicine of USC

Luis A. Chui, MDProfessor of Neurology UC Irvine Health

Jeff Guptill, MD, MA, MHSAssistant Professor of Neurology Division of Neuromuscular Diseases Duke University Medical Center

Madhuri Hegde, PhD, FACMGProfessor of Neurology Executive Director, Emory Genetics Lab Emory University Hospital, Atlanta

Nicholas Johnson, MDAssistant Professor of Neurology, Pediatrics and Pathology University of Utah Healthcare

Chafic Karam, MDAssistant Professor of Neurology University of North Carolina at Chapel Hill

Jonathan S. Katz, MDForbes Norris MDA/ALS Research and Treatment Center, San Francisco

Richard A. Lewis, MDDirector EMG Lab/Co Director Neuromuscular Clinic Cedars-Sinai, Los Angeles

Shri Mishra, MDProfessor of Neurology UCLA David Geffen School of Medicine

Jeffrey W. Ralph, MDAssociate Clinical Professor of Neurology UCLA, David Geffen School of Medicine

Jeffrey Rosenfeld, MD, PhDProfessor of NeurologyLoma Linda University Medical Center

David S. Saperstein, MDPhoenix Neurological Associates Clinical Associate Professor of Neurology at the University of Arizona College of Medicine

Perry Shieh, MD, PhDAssociate Professor and Director, Neuromuscular Program UCLA David Geffen School of Medicine

Werner Stenzel, MDProfessor of Neuropathology Charite’ Center Charite’– Universitätsmedizin Berlin

Leo Wang, MDAssistant Professor WOT, Neurology University of Washington Medical Center Seattle

Program

7 a.m. Registration and Continental Breakfast

8 a.m. Introduction and Opening RemarksSteven L. Small, MD, PhD | Chair, UC Irvine Health Department of NeurologyTahseen Mozaffar, MD, PhD | Professor, UC Irvine Health Department of Neurology

8:10 a.m. Keynote LectureImmune Diabetic NeuropathySpeaker: Vera Bril, MD, FRCP(C) | University of TorontoModerator: Annabel K. Wang, MD

8:40 a.m. Live Case Presentation (2 cases, 30 minutes each)Moderator: Namita Goyal, MD and Jeffrey Ralph, MD

9:40 a.m. Morning Break

10 a.m. 6th Annual Mathilda Karel Spak LectureControversies and Consensus in the Management of Myasthenia GravisSpeaker: Michael Benatar, MD | University of MiamiModerator: Namita Goyal, MD

10:30 a.m. Live Cases (3 cases, 30 minutes each)Moderator: Richard Lewis, MD and Jeffrey Rosenfeld, MD, PhD

Noon Lunch Buffet

1 p.m. Poster Presentations (Attendance Required for CME Credit)Moderators: Shri Mishra, MD and Said Beydoun, MD

1:30 p.m. Research Highlights Blitz (15 minutes each)Moderator: Chafic Karam, MD• Madhuri Hegde, PhD (Emory University) – Free LGMD genetic testings – results to date.• Nicholas Johnson, MD (University of Utah) – Myotonic dystrophy. • Leo Wang, MD (University of Washington) – Physician assisted suicide in ALS:

The Washington and Oregon experience. • Jeff Guptill, MD (Duke University) – Immunophenotype in MG and IBM.

2:30 p.m. Are Muscle Biopsies Still Relevant to Diagnose Myopathies?Speaker: Werner Stenzel, MD, PhD | (Institut fur Neuropathologie, Charite, Berlin) Introduction: Tahseen Mozaffar, MDModerator: Perry Shieh, MD PhD

3 p.m. Afternoon Break

3:30 p.m. RRNMF – Further cases from the RRNMFSpeaker: Jonathan Katz, MD

4 p.m. Case Vignettes Round (6 cases, 10 minutes each, 5 minutes discussion)Moderators: Luis Chui, MD and David Saperstein, MD

5:30 p.m. Closing Remarks and Adjournment

Registration Information

Registration FeesBreakfast and lunch included with registration

MD, DO, PhD, PharmD: $100

Nurses and all other allied healthcare professionals: $50

UC Irvine Health neurologists, residents and fellows: Complimentary

Registration OptionsOption 1: Registration online

Visit www.neurology.uci.edu/neuromuscular-cme to register and pay online with a credit card.

Option 2: Registration by mail/check

Checks must be made payable to UC Regents. Please fill out the form below and mail it with your check to:

UC Irvine Health – Business Development Office 333 City Blvd. West, Suite 200, Orange, CA 92868

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For questions or more information, please contact our business office at 714-456-7200 or email lgumser@uci.edu.

Cancellation policyCancellations received by May 1, 2016, will receive a full refund. No refunds will be made thereafter. Send cancellation requests by email to lgumser@uci.edu or by fax at 714-456-7713.

Accreditation StatementThe University of California, Irvine School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation StatementThe University of California, Irvine School of Medicine designates this live activity for a maximum of 8 AMA PRA Category 1 Credits.™ Physicians should claim only the credit commensurate with the extent of their participation in the activity. The American Board of Psychiatry and Neurology has reviewed the 6th Annual Neuromuscular Colloquium and has approved this program as part of a comprehensive educational program, which is mandated by the ABMS as a necessary component of maintenance of certification.

Disclosure PolicyIt is the policy of the University of California, Irvine School of Medicine and the University of California CME Consortium to ensure balance,

independence, objectivity and scientific rigor in all CME activities. Full disclosure of conflicts and conflict resolutions will be made prior to the activity in writing via handout materials, insert, or syllabus. Speaker/Planner disclosure information will be provided to participants in advance of the program.

ADA StatementIn compliance with the Americans with Disabilities Act, we will make every reasonable effort to accommodate your needs. For any special requests, please contact Laurie Gumser at lgumser@uci.edu or 714-456-3707 by May 1, 2016.

California Assembly Bill 1195This activity is in compliance with California Assembly Bill 1195, which requires continuing medical education activities with patient care components to include curriculum in the subjects of cultural and linguistic competency. For specific information regarding Bill 1195 and definitions of cultural and linguistic competency, please visit the CME website at www.cme.uci.edu.