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Page 1: 7 International Congress on Physical Education and Sport Sciencesprofdoc.um.ac.ir/articles/a/1014648.pdf · 7th International Congress on Physical Education and Sport Sciences March

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Page 2: 7 International Congress on Physical Education and Sport Sciencesprofdoc.um.ac.ir/articles/a/1014648.pdf · 7th International Congress on Physical Education and Sport Sciences March

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��References:��

1.Franks S, McCarthy M. Genetics of ovarian disorders: Polycystic ovary syndrome . Rev Endocr Metab Disord. 2004; 5(1):69-76. 2. Vigorito, C., Giallauria, F., Palomba, S., Cascella, T., Manguso, F., Lucci, R., De Lorenzo, A., Tafuri, D., Lombardi, G., Colao, A. & Orio, F. (2007) Beneficial effects of a three-month structured exercise training program on the cardiopulmonary functional capacity in young women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 92, 1379–1384. 3. Palomba1 S ,. Giallauria F, Falbo1 A, Russo T, Oppedisano R, Tolino A, Colao A,Vigorito C, Zullo F , Orio F. Structured exercise training programme versus hypocaloric hyperproteic diet in obese polycystic ovary syndrome patients with anovulatory infertility: a 24-week pilot study. Human Reproduction 2007;1–9. 4. Orio, F. Jr, Giallauria, F., Palomba, S., Cascella, T., Manguso, F., Vuolo, L., Russo, T., Tolino, A., Lombardi, G., Colao, A. & Vigorito, C. (2006) Cardiopulmonary impairment in young women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 91, 2967–2971. 5. Orio, F. Jr, Palomba, S., Spinelli, L., Cascella, T., Tauchmanovà, L., Zullo, F., Lombardi, G. & Colao, A. (2004) The cardiovascular risk of young women with polycystic ovary syndrome: an observational, analytical, prospective case-control study. Journal of Clinical Endocrinology and Metabolism, 89, 3696–3701. 6. Birdsall, M.A., Farquar, C.M. & White, H.D. (1997) Association between polycystic ovaries and extent of coronary artery disease in women having cardiac catheterization. Annals of International Medicine, 126, 32–35.

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Page 3: 7 International Congress on Physical Education and Sport Sciencesprofdoc.um.ac.ir/articles/a/1014648.pdf · 7th International Congress on Physical Education and Sport Sciences March

����������� �������� ����������������������� ���� !"� �

7th

International Congress on

Physical Education and Sport Sciences �#�$"%&''(�����)"�* March 2010 –Tehran, Iran

Effect of 12 week aerobic training program on cardiovascular risk factors,

hormonal and metabolical alterations in young women with polycystic ovary

syndrome

Sardar. Mohammadali (PhD) : Mashhad Medical Sciences [email protected]

Attarzadeh reza (PhD) : Ferdowsi University of mashad- [email protected]

Taghavi morteza(PhD) : Mashhad Medical Sciences University - e-mail :[email protected]

Ayaz fahimeh(MA) : Mashhad Medical Sciences University - [email protected]

Introduction:Polycystic ovary syndrome (Pcos) is an endocrine disease which is

characterized by un ovulation, hirsutism, acne, hyperandrogenism, impaired glucose

tolerance, insulin resistance and obesity(1) . Life style modifications are successfully

employed to treat obese and over weight women with Pcos. In spite of these CVR

factors metabolic disorders, increased impaired glucose tolerance, diabetes and also

dislipidimia, there are no adequate data documenting the effects of a structured

aerobic exercise program in Pcos women(2). The aim of this study was to evaluate the

effect of aerobic training program on the obesity and insulin resistance in young

women with Pcos.��

Methods: This study was semiexprimental and pre-post test design was used.

Statistical society of the study includes all patients with Pcos who were under

treatment in special clinic of Qaem hospital in Mashad. Statistical samples were 20

patient with Pcos aged 15-25 years old who voluntarily participated in program.

Aerobic training program was performed for 12-weeks, 3 sessions per week, 45-60

minutes per session on bicycle ergometer, elliptical, treadmill with the intensity of

50-60 %vo2max(3).Body weight, FAT% , BMI, WHR, WC, Cl ,TG, HDL-C, LDL-C,

Fasting glucose, Fasting insulin, Insulin Resistance, LH, FSH, Testosterone, DHEA

were assessed at base line and after 12-week aerobic training program. Smirnov-

Kolmogrov test was used to insuring of natural data disturbances. Deference between

means of pre and post training was assessed through dependent t student test with

p<0/05.

Results: After 12-week aerobic training program showed significant improvements in

BW, WC, FAT% , Vo2max, LH, CL, HDL-C, LDL-C, but changes in BMI, WHR,

Fasting glucose, Fasting insulin, IR, FSH, Testosterone, DHEA, and TG were not

significant.

Conclusions: 12-week aerobic training program improves some of the

anthropometric parameters, metabolic and hormonal profiles. To day it no known that

Pcos patient showed impaired maximal and sub maximal cardiopulmonary responses

to exercise compared with age and BMI matched healthy women(4). These finding

seems to be related to several mechanisms and factors including IR and myocardial

and skeletal muscle energy metabolism(5,6). Therefore pcos women should follow an

aerobic training program throughout life in order to improve cardiopulmonary

functional capacity and insulin sensitivity parameters conferring a significant long-

term prognostic advantage. Further studies will be mandatory to extend our results to

a larger and older pcos women population.

Key words: polycystic ovary syndrome (Pcos), obesity, insulin resistance, aerobic

training.�

Page 4: 7 International Congress on Physical Education and Sport Sciencesprofdoc.um.ac.ir/articles/a/1014648.pdf · 7th International Congress on Physical Education and Sport Sciences March

����������� �������� ����������������������� ���� !"� �

7th

International Congress on

Physical Education and Sport Sciences �#�$"%&''(�����)"�* March 2010 –Tehran, Iran

References: 1.Franks S, McCarthy M. Genetics of ovarian disorders: Polycystic ovary syndrome . Rev Endocr Metab Disord. 2004; 5(1):69-76. 2. Vigorito, C., Giallauria, F., Palomba, S., Cascella, T., Manguso, F., Lucci, R., De Lorenzo, A., Tafuri, D., Lombardi, G., Colao, A. & Orio, F. (2007) Beneficial effects of a three-month structured exercise training program on the cardiopulmonary functional capacity in young women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 92, 1379–1384. 3. Palomba1 S ,. Giallauria F, Falbo1 A, Russo T, Oppedisano R, Tolino A, Colao A,Vigorito C, Zullo F , Orio F. Structured exercise training programme versus hypocaloric hyperproteic diet in obese polycystic ovary syndrome patients with anovulatory infertility: a 24-week pilot study. Human Reproduction 2007;1–9. 4. Orio, F. Jr, Giallauria, F., Palomba, S., Cascella, T., Manguso, F., Vuolo, L., Russo, T., Tolino, A., Lombardi, G., Colao, A. & Vigorito, C. (2006) Cardiopulmonary impairment in young women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 91, 2967–2971. 5. Orio, F. Jr, Palomba, S., Spinelli, L., Cascella, T., Tauchmanovà, L., Zullo, F., Lombardi, G. & Colao, A. (2004) The cardiovascular risk of young women with polycystic ovary syndrome: an observational, analytical, prospective case-control study. Journal of Clinical Endocrinology and Metabolism, 89, 3696–3701. 6. Birdsall, M.A., Farquar, C.M. & White, H.D. (1997) Association between polycystic ovaries and extent of coronary artery disease in women having cardiac catheterization. Annals of International Medicine, 126, 32–35.�