8 annual new engla - worcester polytechnic institute · keynote seminar- dr shyamala maheswaran...
TRANSCRIPT
Worcester Polytechnic Institute
60 Prescott St Worcester, MA 01605
Contact: [email protected]
Monday May 21, 2018
9:00am Arrival and Continental Breakfast 60 Prescott Lobby
9:25-9:30 Welcome and Opening Remarks Rm 1002
9:30-10:00 Paul Kaufman (UMMS) Ki-67: more than a proliferation marker
10:00-10:30 Arminja Kettenbach (Dartmouth Medical School) Phosphorylation signaling by phosphoprotein phosphatase 6 in mitosis
10:30-11:00 Rachel Flynn (Boston University) Defining the Replication Stress Response at Telomeric DNA
11:00-11:30 Melinda Day (Cyteir) Targeting the AID/RAD51 Axis: A novel gain of function synthetic lethal approach in DNA repair targeted
11:30-1:00 Lunch Seating available in the event room, the café, & outside patio
Hampton Inn
1:00-1:30 Margaret Pruitt (WPI) Epigenetic Regulation of mitotic fidelity
1:30-2:00 Christine Beck (Jackson Laboratory/UConn) Repetitive sequences and genomic plasticity
2:00-2:30 Kirsten Tracy (UVM) Mitotically-Associated lncRNA, MANCR, Affects Genomic Stability and Cell Division in Breast Cancer
2:30-3:00 Coffee Break and Poster Setup Lobby
3:00-4:00 Keynote Seminar- Dr Shyamala Maheswaran (MGH) Epithelial to Mesenchymal Transition, a dynamic process contributing to genomic instability
4:00-6:00 Wine and Cheese Reception and Poster Session Lobby
8th Annual New England Genome Instability and Cancer
Conference
Worcester Polytechnic Institute
60 Prescott St Worcester, MA 01605
Contact: [email protected]
Poster Session
Presenter Institution Title
Stephanie Joy Bouley
Geisel School of Medicine at Dartmouth
Targeting NF1-dysregulated tumors using a synthetic lethal approach
Elizabeth Crowley WPI Mitotic DNA damage in cells lacking pRB
Amber Cyr Cyteir Therapeutics Measuring the Effects of Cyteir Small Molecules on DNA Repair Proteins
Chihiro Emori
The Jackson Laboratory Defining the mechanisms of cancer therapy-induced ovarian toxicity
Andrew Fritz
University of Vermont
RUNX1 depletion increases breast cancer aggressiveness and delays response to DNA damage
Dipika Gupta
UConn Health
Intra-S Phase Checkpoint Activation Mitigates Replication Stress Caused by Mismatch Repair Processing of DNA Damage
Nicole Hermance WPI Chromosome Instability is Sensitive to Manipulation of Cohesion
Kristyna Kotynkova
Boston University
Loss of SPINT2 promotes YAP activation and tolerance to aneuploidy
Tyler Maclay
Cyteir Therapeutics
TBD
Sumeet Nayak
UMMS
The FANCJ-BRCA1 interaction directs replication fork dynamics to counter replicative bypass and chemo-resistance upon replication stress.
Leslie Sepaniac
University of Vermont
Different mechanisms of micronucleus formation and impact to genomic stability
Alex Thompson
University of Vermont Effects of post-translational modification on the mitotic kinesin Eg5