9th annual international clinical cancer genetics … brochure_15.pdfmolecular medicine deputy...

GENETICSIN CLINICAL CANCER CARE:FROM FAMILY REUNIONS TO THE FRONTLINEOF DEVELOPMENTAL THERAPEUTICS 2020

IN PARTNERSHIP WITH:

IN CONJUNCTION WITH THE PERSONALIZED CANCER CARE CONSORTIUM

REGISTER ONLINE:cme.uchicago.edu/CancerGenetics2020

APRIL 17-19, 2020 | FAIRMONT CHICAGO MILLENNIUM PARK

9TH ANNUAL INTERNATIONAL CLINICAL CANCER GENETICS AND GENOMICS CONFERENCE

CONFERENCE DIRECTOROlufunmilayo Olopade, MDUniversity of Chicago Medicine

CONFERENCE CO-DIRECTORSSonia Kupfer, MDOlatoyosi Odenike, MDIris Romero, MD, MSWalter Stadler, MDUniversity of Chicago Medicine

Kathleen Blazer, EdD, MS, LCGC Jeffrey Weitzel, MD City of Hope National Medical Center

NOW OFFERINGABIM MOC II CREDIT!

TARGET AUDIENCEThisactivityisdesignedforphysicians,physicianassistants,advancednursepractitioners,geneticcounselors,oncologynurses,andotherhealthcareprofessionalscurrentlyprovidingoncologycareandcancergeneticsriskassessmentservicesorinitiatingsuchcareandservicesintheirhealthcaresystem.Specialeffortswillbemadetoeducateclinicianspracticingingeographicallyorsocioeconomicallyunderservedcommunities.

LEARNING OBJECTIVESAttheconclusionofthisactivity,participantswillbeableto:

·· Recalladvancedconceptsingenetics,genomics,andnextgenerationsequencing(NGS)technologies.

·· Analyzecontroversiesincancerriskassessmentandgenetictestingincludingtheintegrationofpolygenicriskscores.

·· RecognizehowscientificadvancesinLynchsyndromeandotherinheritedsolidtumorsandhematologicmalignanciescanimprovetheclinicalmanagementofpatients.

·· Discusshowtheintegrationofnovelcancertherapiesbasedongenomicalterationsintumortissuemayrevealgermlinemutationsthatcanguidepatientmanagement.

·· Recognizethelimitationsofgenomictestingasitrelatestobothcancerriskaswellastherapeuticselection,includingvariantsofuncertainsignificanceandinsilicopredictions.

·· Identifyhowaglobally-informedperspectiveonexperimentaltherapeuticsforrarecancersincludingimmunotherapycanimprovepatientoutcomes.

·· Discusshowemergingconceptsincancerinterceptionandcancerriskmodifiersincludinglifestyleandchemopreventioncanimpactdiseasemanagementstrategies.

·· Statetheethical,legal,andsocialimplicationsofgenomictestingindiversepopulations.

PHYSICIAN CREDITTheUniversityofChicagoPritzkerSchoolofMedicineisaccreditedbytheAccreditationCouncilforContinuingMedicalEducationtoprovidecontinuingmedicaleducationforphysicians.

TheUniversityofChicagoPritzkerSchoolofMedicinedesignatesthisliveactivityforamaximumof19.0AMA PRA Category 1 CreditsAMA PRA Category 1 Credits™™.Physiciansshouldclaimonlythecreditcommensuratewiththeextentoftheirparticipationintheactivity.

OTHER HEALTHCARE PROFESSIONAL CREDITNursesandotherhealthcareprofessionalswillreceiveaCertificateofParticipation.ForinformationontheapplicabilityandacceptanceofCertificatesofParticipationforeducationalactivitiescertifiedforAMA PRA Category 1 CreditsAMA PRA Category 1 Credits™™fromorganizationsaccreditedbytheACCME,pleaseconsultyourprofessionallicensingboard.

GENETIC COUNSELOR CEUsThiseventhasbeensubmittedtotheNationalSocietyofGeneticCounselors(NSGC)forapprovalofCategory1CEUs.TheAmericanBoardofGeneticCounseling(ABGC)acceptsCEUsapprovedbyNSGCforpurposesofrecertification.ApprovalfortherequestedCEUsandContactHoursiscurrentlypending.

AMERICAN BOARD OF INTERNAL MEDICINE MOC PART II CREDITSuccessfulcompletionofthisCMEactivity,whichincludesparticipationintheevaluationcomponent,enablestheparticipanttoearnupto19MOCpointsintheAmericanBoardofInternalMedicine’s(ABIM)MaintenanceofCertification(MOC)program.ParticipantswillearnMOCpointsequivalenttotheamountofCMEcreditsclaimedfortheactivity.ItistheCMEactivityprovider’sresponsibilitytosubmitparticipantcompletioninformationtoACCMEforthepurposeofgrantingABIMMOCcredit.

DISCLOSURE DECLARATIONSAsaprovideraccreditedbytheACCME,TheUniversityofChicagoPritzkerSchoolofMedicineaskseveryonewhoisinapositiontocontrolthecontentofaneducationalactivitytodiscloseallrelevantfinancialrelationshipswithanycommercialinterest.Thisincludesanyentityproducing,marketing,re-selling,ordistributinghealthcaregoodsorservicesconsumedbyorusedonpatients.

TheACCMEdefines“relevantfinancialrelationships”asfinancialrelationshipsinanyamountoccurringwithinthepast12months,includingfinancialrelationshipsofaspouseorlifepartnerthatcouldcreateaconflictofinterest.Mechanismsareinplacetoidentifyandresolveanypotentialconflictofinterestpriortothestartoftheactivity.

Additionally,TheUniversityofChicagoPritzkerSchoolofMedicinerequiresauthorstoidentifyinvestigationalproductsoroff-labelusesofproductsregulatedbytheUSFoodandDrugAdministrationatfirstmentionandwhereappropriateinthecontent.

COURSE DESCRIPTIONThisactivitywillprovideaninterdisciplinaryeducationalforuminwhichtoupdatestate-of-the-artscienceincludingnoveltherapiesforinheritedcancers,discussreal-worldcases,curateinterestingpedigreesandpreparecasesummariestodisseminatenewknowledgeintranslationalgenomicsandevidence-basedclinicalmanagementofhigh-riskpatientsandtheirfamilymembers.

INFORMATION

INFORMATION

EDUCATIONAL GRANTS/COMMERCIAL SUPPORTAcompletelistofcommercialsupportreceived

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LOCATION AND ACCOMMODATIONSWeareexcitedandpleasedtobemovingto

theFairmontChicagoin2020!AtChicago’s

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Chicago,MillenniumParkofferscontemporary

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CancerGenetics2020eventorbookonlineat:

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PARKING:Pleasecallthehotelregardingdayrates

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TRAVEL AWARDSFundsareavailableformerit-andneed-

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submissionofinterestingpedigreestoinclude

intheconferenceproceedings.Traineesin

geneticcounseling,nursingorclinicaloncology

trainingprogramsandjuniorfacultymembersare

encouragedtoapplyfortravelawards.Potential

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foreligibilitybytheorganizingcommitteebased

bothon1)Hisorherrepresentativenessasan

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cancerriskassessmentservicestounderserved

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populationsand2)Statementoflimitedor

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SubmissionsaredueMarch1,2020.

Interestedapplicantsshouldapplyat:

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cme.uchicago.edu/CancerGenetics2020

FACULTY

INTERNATIONAL GUEST FACULTY

Prisca Adejumo, RN, BSc, MSc, PhDLecturerUniversityofIbadanIbadan,Nigeria

Marcia Cruz Correa, MD, PhDProfessorofMedicineandBiochemistryUniversityofPuertoRicoComprehensiveCancerCenterSanJuan,PuertoRico

Diana Eccles, MDDeanofMedicineProfessorofCancerGeneticsUniversityofSouthamptonSouthampton,England

Rodrigo Guindalini, MD, PhDMedicalOncologyandOncogeneticsOncologiaD’orSalvador,Brazil

Ava Kwong, MBBS, PhDDanielCKYuProfessorinBreastCancerResearchClinicalProfessoroftheDepartmentofSurgeryUniversityofHongKong

Kelly Metcalfe, RN, PhDAssociateDean,ResearchandExternalRelationsProfessorLawrenceS.BloombergFacultyofNursingUniversityofTorontoToronto,Canada

Steven Narod, MDSeniorScientist,Women’sCollegeResearchInstituteDirector,FamilialBreastCancerResearchUnit,Women’sCollegeResearchInstituteProfessor,DallaLanaSchoolofPublicHealth,UniversityofTorontoProfessor,DepartmentofMedicine,UniversityofTorontoTier1CanadaResearchChairinBreastCancerToronto,Canada

Jacques Simard, PhDProfessor,DepartmentofMolecularMedicineDeputyDirector,BasicResearchCHUdeQuébecResearchCentre-UniversitéLavalQuébec,Canada

Soo Hwang Teo, PhD, OBEHeadofBreastCancerResearchProgramCancerResearchMalaysiaSelangor,Malaysia

GUEST FACULTY

C. Richard Boland, MDProfessorofMedicineDepartmentofMedicine,DivisionofGastroenterologyUCSanDiegoSchoolofMedicine

Stephen Chanock, MDDirector,DivisionofCancerEpidemiology&GeneticsNationalCancerInstitute

Heather Cheng, MD, PhDAssistantProfessorDepartmentofMedicine,DivisionofOncologyUWMedicineMedicalOncologyUniversityofWashington

Jane Churpek, MD, MSAssistantProfessorDepartmentofMedicineUniversityofWisconsinSchoolofMedicineandPublicHealth

Laurie Connors, DNPAssociateProfessorVanderbiltUniversity

Allison DePersia, MDClinicalAssistantProfessorInternalMedicine,MedicalOncologyNorthShoreUniversityHealthSystem

Judy Garber, MD, MPHDirector,CenterforCancerGeneticsandPreventionSusanF.SmithChairInstitutePhysicianProfessorofMedicine,HarvardMedicalSchoolDana-FarberCancerInstitute

Michael Hall, MD, MSChair,DepartmentofClinicalGeneticsAssociateProfessor,DepartmentofClinicalGeneticsDirector,GastrointestinalRiskAssessmentFoxChaseCancerCenter

Heather Hampel, MS, LGCLicensedGeneticCounselorOhioStateUniversityWexnerMedicalCenter

Karen Hurley, PhDLicensedClinicalPsychologistClevelandClinic

Huiping Liu, MD, PhDAssociateProfessorofPharmacologyandMedicineHematologyandOncologyNorthwesternMedicine

Patrick Lynch, MDProfessor,DepartmentofGastroenterologyDivisionofInternalMedicineTheUniversityofTexasMDAndersonCancerCenter

Steven Maron, MD, MScMedicalOncologistMemorialSloanKetteringCancerCenter

Robert Nishikawa, PhDProfessorDepartmentofRadiologyImagingResearchLaboratoryUniversityofPittsburgh

Kenneth Offit, MD, MPHChief,ClinicalGeneticsServiceRobertandKateNiehausChairinInheritedCancerGenomicsViceChair,AcademicAffairs,DepartmentofMedicineMemorialSloanKetteringCancerCenter

Julie Palmer, ScDProfessor,EpidemiologyBostonUniversitySchoolofPublicHealth

Gloria Petersen, PhDPurvisandRobertaTaborProfessorProfessorofEpidemiologyMayoClinic

Colin Pritchard, MD, PhDAssociateProfessor,GeneticsAssociateDirector,GeneticsandSolidTumorsLaboratoryUniversityofWashingtonSchoolofMedicine


CONTINUED...

FACULTY

GUEST FACULTY Continued...

Timothy Rebbeck, PhDVinventL.GregoryProfessorofCancerPreventionHarvardT.H.ChanSchoolofPublicHealthDana-FarberCancerInstitute

Laura van’t Veer, PhDLeader,BreastOncologyProgramDirector,AppliedGenomicsAngelaandShuKaiChanEndowedChairinCancerResearchUCSFHelenDillerFamilyComprehensiveCancerCenter

Elad Ziv, MDProfessorDepartmentofMedicineUCSFHelenDillerFamilyComprehensiveCancerCenter

THE UNIVERSITY OF CHICAGO FACULTY

Yasmin Asvat, PhDAssistantProfessorofPsychiatryandBehavioralNeuroscience

Jean Bao, MDAssistantProfessorofSurgery

Christine Bestvina, MDAssistantProfessorofMedicine

Soma Das, PhDDirector,MolecularDiagnosticLaboratory

Michael Drazer, MDClinicalInstructorofMedicine

Scott Eggener, MDProfessorofSurgeryandRadiologyDirector,ProstateCancerProgramCo-Director,HighRisk&AdvancedProstateCancerClinicDirector,TranslationalandOutcomesResearch,SectionofUrology

Gini Fleming, MDProfessorofMedicineMedicalOncologyDirector,GynecologicOncology

Feighanne Hathaway, MS, CGCGeneticCounselor

Andrzej Jakubowiak, MD, PhDProfessorofMedicineDirector,MyelomaProgram

Jagoda Jasielec, MDAssistantProfessorofMedicine

Nora Jaskowiak, MDProfessorofSurgerySurgicalDirector,BreastCancer

Hedy Kindler, MDProfessorofMedicineMedicalDirector,GastrointestinalOncologyDirector,MesotheliomaProgram

Sonia Kupfer, MDAssociateProfessorofMedicineDirector,GastrointestinalCancerRiskandPreventionClinicCo-Director,ComprehensiveCancerRiskandPreventionClinic

Olatoyosi Odenike, MDAssociateProfessorofMedicine

Peter O’Donnell, MDAssociateProfessorofMedicine

Olufunmilayo Olopade, MDWalterL.PalmerDistinguishedServiceProfessorofMedicineandHumanGeneticsDirector,CenterforClinicalCancerGenetics&GlobalHealth

Alexander Pearson, MD, PhDAssistantProfessorofMedicine

Blasé Polite, MDAssociateProfessorofMedicine

Padma Sheila Rajagopal, MDPostdoctoralResearchFellow

Iris Romero, MD, MSAssociateProfessorofObstetricsandGynecologyDeanforDiversityandInclusion

Deepa Sheth, MDAssistantProfessorofRadiologyAssistantDirectorofMedicalEducation

Shari Snow, MDAssociateProfessorofObstetricsandGynecologySectionChief,GynecologyandMinimallyInvasiveSurgery

Walter Stadler, MDFredC.BuffettProfessorofMedicineandSurgeryDeanforClinicalResearchDirector,GenitourinaryOncologyProgramDeputyDirector,ComprehensiveCancerCenter

Randy Sweis, MDAssistantProfessorofMedicine

Russell Szmulewitz, MDAssociateProfessorofMedicine

CITY OF HOPE FACULTY

Kathleen Blazer, EdD, MS, LCGCAssociateDirector,CancerGenomicsEducationProgramCo-director,IntensiveCourseinCancerRiskAssessmentCo-investigator,CancerGenomicsCareerDevelopmentProgramClinicalAssistantProfessor

Amrita Krishnan, MD DirectoroftheJudyandBernardBriskinCenterforMultipleMyelomaResearchProfessor,DepartmentofHematology&HematopoieticCellTransplantation

Thomas Slavin, MDClinicalGeneticistAssistantClinicalProfessor,DepartmentsofMedicalOncology&TherapeuticsResearchandPopulationSciences,DivisionofClinicalCancerGenomics

Jeffrey Weitzel, MDDirector,DivisionofClinicalCancerGenomicsDirector,CancerScreening&PreventionProgramsNetworkDirector,CancerGenomicsEducationProgramProfessor,DepartmentofMedicalOncology&TherapeuticsResearchandDepartmentofPopulationSciences


FRIDAY, APRIL 17, 2020

7:30am CONTINENTAL BREAKFAST AND REGISTRATION

8:00am WELCOMEOlufunmilayoOlopade,MDWalterStadler,MD

ADVANCED CONCEPTS IN SOMATIC AND GERMLINE GENETICS Moderators SomaDas,PhD AllisonDePersia,MD

8:05am Somatic and Germline Genomics – Lessons Learned from Liquid BiopsiesThomasSlavin,MD

8:25am KEYNOTE ADDRESS ISingle-cell RNA Sequencing and Single-cell Proteomics to Understand Heterogeneity HuipingLiu,MD,PhD

8:55am What Do Mutational Signatures Tell Us About Heritable Risk Factors and Targeted Therapy? ColinPritchard,MD,PhD

9:25am Q&A WITH SPEAKERS

9:40am BREAK

DAWN OF A NEW ERA Moderators MichaelDrazer,MD PadmaSheilaRajagopal,MD

10:00am KEYNOTE ADDRESS IIEmerging Approaches To Population Screening For Cancer Susceptibility KennethOffitt,MD,MPH

10:30am Rethinking Li Fraumeni Syndrome (SBLA) 50 Years LaterJudyGarber,MD,MPH

10:50am New Pathway to FDA Approval: How Genomic Biomarkers are Transforming Drug ApprovalProcess for the I-SPY NetworkLauravan’tVeer,PhD

11:20am Pharmacogenomics Implementation for Oncology

PeterO’Donnell,MD


12:00pm Case Presentations

Moderators KathleenBlazer,EdD,MS,LCGC

LaurieConnors,DNP

FeighanneHathaway,MS,CGC

KellyMetcalfe,RN,PhD

1:00pm LUNCH: Non-CME Activities

PARALLEL SESSION: CLINICAL CANCER GENETICS Moderators OlufunmilayoOlopade,MD

JeffreyWeitzel,MD

2:15pm Genetic Testing in Diverse Populations in South America

RodrigoGuindalini,MD,PhD

2:35pm Uptake of Risk Reducing Surgery in South America

JefferyWeitzel,MD

3:05pm Genetic Predisposition to Breast Cancer in Asian Women

SooHwangTeo,PhD,OBE

3:25pm Nurses and Genetic Counseling and Testing in Nigeria

PriscaAdejumo,RN,BSc,MSc,

PhD

3:45pm KEYNOTE ADDRESS III Implementation of Personalized Risk Assessment for Risk-Based Breast Cancer Screening in Canada

JacquesSimard,PhD

4:15pm Q&A WITH SPEAKERS

AGENDA


PARALLEL SESSION: DEVELOPMENTAL THERAPEUTICS FOR ADVANCED CANCERS Moderators OlatoyosiOdenike,MD

WalterStadler,MD

2:15pm Prostate CancerRussellSzmulewitz,MD

2:35pm Myelodysplastic and Myeloproliferative Diseases

OlatoyosiOdenike,MD

2:55pm Lung CancerChristineBestvina,MD

3:15pm Pancreatic CancerHedyKindler,MD

3:35pm GI/Esophageal Therapeutics

StevenMaron,MD,MSc

3:55pm KEYNOTE ADDRESS IIICurative Therapy for MGUS and Multiple Myeloma AndrzejJakubowiak,MD,PhD

4:30pm BREAK

5:00pm Great Debate: Genomic Testing is Harmful to Individuals and Society

StephenChanock,MD

vs.OlufunmilayoOlopade,MD

6:00pm RECEPTION AND POSTER SESSION

SATURDAY, APRIL 18, 2020

7:30am CONTINENTAL BREAKFAST

8:00am ANNOUNCEMENTS

IrisRomero,MD,MS

LYNCH SYNDROME I Moderators SoniaKupfer,MD BlaséPolite,MD

8:05am KEYNOTE ADDRESS IVDefining Lynch Syndrome: Genetic and Phenotypic Heterogeneity C.RichardBoland,MD

8:35am Mismatch Repair Deficiency and Novel Therapeutic Targets in GI CancersBlaséPolite,MD

8:55am Mainstreaming Universal Testing for Lynch Syndrome HeatherHampel,MS,LGC

9:15am New Frontiers in Prevention and Early Detection of Cancer at the Population LevelMarciaCruzCorrea,MD,PhD


9:45am BREAK

LYNCH SYNDROME II Moderators ScottEggener,MD RandySweis,MD

10:15am KEYNOTE ADDRESS V Cancer Immunotherapy Comes of Age for Lynch Families MichaelHall,MD,MS

10:45am Men’s Health – Prostate Cancer, DNA Repair Pathways and Predictive Testing for Inherited Cancers HeatherCheng,MD,PhD

11:05am Personal Perspectives on Lynch Syndrome and Future DirectionsPatrickLynch,MD


11:40am Case PresentationsModerators KathleenBlazer,EdD,MS,LCGC FeighanneHathaway,MS,CGC

12:45pm LUNCH: Non-CME Activities

AGENDA


HEREDITARY BREAST AND OVARIAN CANCER SYNDROME

Moderators IrisRomero,MD,MS

JeanBao,MD

2:00pm KEYNOTE ADDRESS VIObservational Cohort Studies of Treatment Outcomes of Hereditary Breast Cancer StevenNarod,MD

2:30pm Hereditary Breast Cancer Genes and Outcome in Young-Onset Breast Cancer (POSH Study) DianaEccles,MD

3:00pm PARP Inhibitors in BRCA-Associated Cancers GiniFleming,MD


3:45pm BREAK

OTHER SYNDROMES Moderators JagodaJasielec,MD

JaneChurpek,MD,MS

4:15pm KEYNOTE ADDRESS VIIMultiple Myeloma in Populations of African Ancestry TimothyRebbeck,PhD

4:35pm Myeloma: Risk Factors AmritaKrishnan,MD

4:55pm KEYNOTE ADDRESS VIIIPancreatic Cancer and Malignant Melanoma: New Insights on Susceptibility and CDKN2A GloriaPetersen,PhD


5:30pm Great Debate: Mastectomy versus Lumpectomy AvaKwong,MBBS,PhD

vs.NoraJaskowiak,MD

SUNDAY, APRIL 19, 2020

7:30am CONTINENTAL BREAKFAST

8:00am ANNOUNCEMENTS

SoniaKupfer,MD

GENETICS IN PRIMARY CARE & THE POPULATION Moderators ShariSnow,MD

DeepaSheth,MD

8:05am Validity of PRS Score for Subtype Specific Breast Cancer Screening in the US

JuliePalmer,ScD

8:25am PRS in LATINx Populations

EladZiv,MD

8:45am BREAK

9:30am An Ounce of Prevention: Healthy Lifestyle and Interventions to Reduce Stress

YasminAsvat,PhD

10:00am KEYNOTE ADDRESS IX

Advances in Imaging Technologies and AI for Early Detection of Breast CancerRobertNishikawa,PhD

10:30am Panel Discussion: Ethical Considerations for AI and Inherited Cancers

KarenHurley,PhD

AlexanderPearson,MD,PhD

PatientAdvocates

11:30am WRAP UP

AGENDA


PLEASE TYPE OR PRINT

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HOW TO REGISTER

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MAIL – To pay by check, you must mail

this registration form with payment to:

TheUniversityofChicago

CenterforContinuingMedicalEducation

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Make checks (US funds only) payable to:

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CANCELLATION POLICY

Ifyoucancelyourparticipationinthisconference,yourregistrationfee,lessa$100administrativefee,willberefundedwhenwrittennotificationisreceivedbyMarch15,2020.NorefundswillbemadeafterMarch15,2020.

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Foradditionalinformationaboutthisactivity,pleasecontactMeetingAchievementsviaemailatsupport@meetingachievements.com.

REGISTRATION FEE EARLY REGISTRATION DISCOUNT REGULAR RATE EndsMarch15,2020 CODE AsofMarch16,2020

PHYSICIANS o$545 GCMD20 o$630

GENETIC COUNSELORS* o$350 GCGC20 o$395*DoesnotincludeCEUcredit

GENETIC COUNSELORS* o$375 GCGC20 o$420*WithCEUcredit

OTHER HEALTHCARE o$350 GCHP20 o$395 PROFESSIONALS

RESIDENTS/FELLOWS o$245 GCRF20 o$305

INDUSTRY o$600 GCIN20 o$700

REGISTRATION


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9th annual international clinical cancer genetics … brochure_15.pdfmolecular medicine deputy...

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