a new standard of diabetes care · the rigorous performance requirements of the newly established...

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%15/15 * %20/20 MARD Overall § 83.3% 93.9% 9.0% Accuracy over time Day 1 81.5% 92.2% 9.3% Day 2 84.0% 92.3% 8.4% Days 4-5 85.8% 95.5% 9.4% Day 7 82.1% 97.3% 8.7% Day 10 82.4% 92.5% 9.0% Dexcom G6 ® Defines a New Standard in CGM Performance Recently published studies 1,2 evaluating the performance of the Dexcom G6 Continuous Glucose Monitoring (CGM) System demonstrate that it not only meets the rigorous performance requirements of the newly established Class II iCGM device category (“Integrated CGM”), but also scores high for patient usability. A New Standard of Diabetes Care CGM First Dexcom G6 Accuracy Metrics Strong Day 1 performance and consistent accuracy over time 1 Accuracy metrics were derived from raw sensor data that was reprocessed using assigned codes for each sensor and a factory-calibrated algorithm. The data set consisted of 3,532 temporally matched CGM-YSI pairs. Exceptional performance for both pediatric and adult patients 1 PEDS %15/15 %20/20 MARD Overall 91.1% 96.2% 7.7% Abdomen insertion site 97.6% Upper buttocks insertion site 94.2% ADULTS %15/15 %20/20 MARD Overall 78.3% 92.5% 9.8% * % of CGM readings within ±15 mg/dL of YSI lab reference values ≤ 100mg/dL or ±15% of YSI values > 100mg/dL. Analogous to %15/15 (see previous footnote). MARD is a statistical measure of accuracy; the lower the number, the better. § Unless noted otherwise, adult and pediatric data are combined.

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%15/15* %20/20 MARDOverall§ 83.3% 93.9% 9.0%

Accuracy over time Day 1 81.5% 92.2% 9.3%Day 2 84.0% 92.3% 8.4%Days 4-5 85.8% 95.5% 9.4%Day 7 82.1% 97.3% 8.7%Day 10 82.4% 92.5% 9.0%

Dexcom G6® Defines a New Standard in CGM PerformanceRecently published studies1,2 evaluating the performance of the Dexcom G6 Continuous Glucose Monitoring (CGM) System demonstrate that it not only meets the rigorous performance requirements of the newly established Class II iCGM device category (“Integrated CGM”), but also scores high for patient usability.

A New Standard of Diabetes CareCGM First™

Dexcom G6 Accuracy Metrics

Strong Day 1 performance and consistent accuracy over time1

Accuracy metrics were derived from raw sensor data that was reprocessed using assigned codes for each sensor and a factory-calibrated algorithm. The data set consisted of 3,532 temporally matched CGM-YSI pairs.

Exceptional performance for both pediatric and adult patients1

PEDS %15/15 %20/20 MARDOverall 91.1% 96.2% 7.7% Abdomen insertion site 97.6% Upper buttocks insertion site 94.2%

ADULTS %15/15 %20/20 MARDOverall 78.3% 92.5% 9.8%

* % of CGM readings within ±15 mg/dL of YSI lab reference values ≤ 100mg/dL or ±15% of YSI values > 100mg/dL. † Analogous to %15/15 (see previous footnote). ‡ MARD is a statistical measure of accuracy; the lower the number, the better. § Unless noted otherwise, adult and pediatric data are combined.

References1 Shah VN, Laffel LM, Wadwa RP, Garg SK. Performance of a Factory-Calibrated Real-Time Continuous Glucose Monitoring System Utilizing an Automated Sensor Applicator. Diabetes Technol Ther. 2018. 2 Wadwa RP, Laffel LM, Shah VN, Garg SK. Accuracy of a Factory-Calibrated, Real-Time Continuous Glucose Monitoring System During 10 Days of Use in Youth and Adults with Diabetes. Diabetes Technol Ther. 2018. 3 Schmelzeisen-Redeker G, Schoemaker M, Kirchsteiger H, Freckmann G, Heinemann L, Del Re L. Time Delay of CGM Sensors: Relevance, Causes, and Countermeasures. J Diabetes Sci Technol. 2015;9(5):1006-1015.

BRIEF SAFETY STATEMENT: Failure to use the Dexcom G6 Continuous Glucose Monitoring System (G6) and its components according to the instructions for use provided with your device and available at https://www.dexcom.com/safety-information and to properly consider all indications, contraindications, warnings, precautions, and cautions in those instructions for use may result in you missing a severe hypoglycemia (low blood glucose) or hyperglycemia (high blood glucose) occurrence and/or making a treatment decision that may result in injury. If your glucose alerts and readings from the G6 do not match symptoms, use a blood glucose meter to make diabetes treatment decisions. Seek medical advice and attention when appropriate, including for any medical emergency.

©2018 Dexcom Inc. All rights reserved. LBL016597 Rev 002

Low or high, Dexcom G6 shows outstanding accuracy across glucose ranges.1

Hyperglycemia (%20/20)

181-250 mg/Dl: 92.9%

≥250 mg/dL: 96.2%

Hypoglycemia (%20/20)

<70 mg/dl: 90.8%

Dexcom G6 maintains accuracy for treatment decisions even when glucose levels are rapidly rising or falling.2

Simple and comfortable sensor insertion

Patient-reported outcomes1:

9 out of1020%/20

9 out of 10 Dexcom G6 readingsare within 20%/20 of the YSI value when glucose is falling or rising.

84%of participants

reported no pain or mild pain

100%of participants reported

the auto-applicator was “somewhat” or “very” easy to use

100%of participants reported the

product instructions were “somewhat” or

“very” easy to understand

For more information about Dexcom CGM, visit provider.dexcom.com

Dexcom G6 shows continuous, minimal lag time—an average of 4 minutes.*

*The Dexcom G6 CGM System provides updated estimated glucosevalues (EGVs) every 5 minutes; with every EGV update, there is anaverage lag time of 4 minutes between the glucose level detected bythe G6 sensor in the ISF vs. the blood.

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