a survey report on packaging

8/9/2019 A Survey Report on Packaging

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INTRODUCTION

Pharmaceutical products are typically susceptible to the damaging effects of

moisture. As such, it is imperative to use the right pharmaceutical packaging products,

whether they are being transported or simply stored.

Pharmaceutical grade desiccants: Pharmaceutical grade desiccants such as silica gel

are an excellent way to control moisture levels. Although it is referred to as a gel, silica

gel is actually an extremely porous and granular form of silica derived synthetically from

sodium silicate. Completely non-toxic, it is one of the most effective and safest ways to

protect not only pharmaceuticals, but also food and sensitive materials such as film and

electronics.

Indicating silica gel simply provides a built-in humidity gauge--the desiccant literally

changes color as it absorbs moisture. Humidity indicator cards are exactly as their name

describes--cards that are placed within a package to monitor the current levels of

humidity. These cards also use a simple color-coded system.

Moisture barrier bags: Moisture barrier bags are another effective pharmaceutical

packaging product. Such materials are only necessary if there is a need to completelyeliminate any moisture from getting to the product. If used in combination with a desiccant

such as silica gel, it is the only way to guarantee moisture will be kept at bay.

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include authentication seals to help indicate that the package and contents are not

counterfeit. Packages also can include anti-theft devices, such as dye-packs, RFID tags,

orelectronic article surveillance tags, that can be activated or detected by devices at exit

points and require specialized tools to deactivate. Using packaging in this way is a means

ofloss prevention.

Convenience - Packages can have features which add convenience in distribution,

handling, display, sale, opening, reclosing, use, and reuse.

Portion control - Single serving or single dosage packaging has a precise amount of

contents to control usage. Bulk commodities (such as salt) can be divided into packages

that are a more suitable size for individual households. It is also aids the control of

inventory: selling sealed one-liter-bottles of milk, rather than having people bring their

own bottles to fill themselves.

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PACKAGING TYPES

Various household packaging types for pharmaceutical prodcts:

Packaging may be looked at as several different types. For example a transport

package ordistribution package is the package form used to ship, store, and handle

the product or inner packages. Some identify a consumer package as one which is

directed toward a consumer or household.

Packaging may discussed in relation to the type of product being packaged:

medical device packaging, bulk chemical packaging, over-the-counter drug packaging,

retail food packaging, military materiel packaging, pharmaceutical packaging, etc.

It is sometimes convenient to categorize packages by layer or function: "primary",

"secondary", etc.

Primary packaging: Primary packaging is the material that first envelops the

product and holds it. This usually is the smallest unit of distribution or use and is the

package which is in direct contact with the contents.

Secondary packaging: Secondary packaging is outside the primary

packaging perhaps used to group primary packages together.

Tertiary packaging: Tertiary packaging is used forbulk handling, warehouse

storage and transport shipping. The most common form is a palletizedunit load that

packs tightly into containers.

These broad categories can be somewhat arbitrary. For example, depending on

the use, a shrink wrap can be primary packaging when applied directly to the product,

secondary packaging when combining smaller packages, and tertiary packaging on somedistribution packs.

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SYMBOLS USED ON PACKAGES AND LABELS

Many types of symbols for package labelling are nationally and internationally

standardized. For consumer packaging, symbols exist for product certifications,

trademarks, proof of purchase, etc. Some requirements and symbols exist to

communicate aspects of consumer use and safety. Recycling directions, Resin

identification code (below), and package environmental claims have special codes and

symbols.

Bar codes (below), Universal Product Codes, and RFID labels are common to

allow automated information management.

Shipments of hazardous materials ordangerous goods have special information

and symbols (labels, plackards, etc) as required by UN, country, and specific carrier

requirements. Two examples are below:

With transport packages, standardised symbols are also used to aid in handling.

Some common ones are shown below while others are listed in ASTM D5445 "Standard

Practice for Pictorial Markings for Handling of Goods" and ISO 780 "Pictorial marking for

handling of goods".

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PACKAGE DEVELOPMENT CONSIDERATIONS

Package design and development are often thought of as an integral part of the

new product development process. Alternatively, development of a package (or

component) can be a separate process, but must be linked closely with the product to be

packaged. Package design starts with the identification of all the requirements: structural

design, marketing, shelf life, quality assurance, logistics, legal, regulatory, graphic design,

end-use, environmental, etc. The design criteria, time targets, resources, and cost

constraints need to be established and agreed upon.

Transport packaging needs to be matched to its logistics system. Packages

designed for controlled shipments of uniform pallet loads may not be suited to mixedshipments with express carriers.

An example of how package design is affected by other factors is the relationship

to logistics. When the distribution system includes individual shipments by a small parcel

carrier, the sortation, handling, and mixed stacking make severe demands on the strength

and protective ability of the transport package. If the logistics system consists of uniform

palletized unit loads, the structural design of the package can be designed to those

specific needs: vertical stacking, perhaps for a longer time frame. A package designed for

one mode of shipment may not be suited for another.

Sometimes the objectives of package development seem contradictory. For

example, packaging for an over-the-counter drug might require tamper resistance and

child resistant features: These intentionally make the package difficult to open. The

intended consumer, however, might be handicapped or elderly and be unable to readily

open the package.

Package design may take place within a company or with various degrees of

external packaging engineering: contract engineers, consultants, vendor evaluations,

independent laboratories, contract packagers, total outsourcing, etc. Some sort of formal

Project planning and Project Management methodology is required for all but the simplest

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package design and development programs. An effective quality management system

and verification and validation protocols are mandatory for some types of packaging and

reommended for all.

Package development involves considertions for sustainability, environmental

responsibiity, and applicable environmental and recycling regulations. It may involve a life

cycle assessment which considers the material and energy inputs and outputs to the

package, the packaged product (contents), the packaging process, the logistics system,

waste management, etc. It is necessary to know the relevant regulatory requirements for

point of manufacture, sale, and use.

The traditional three Rs of reduce, reuse, and recycle are part of a waste

hierarchy which may be considered in product and package development.

The waste hierarchy

Prevention Waste prevention is a primary goal. Packaging should be used only where

needed. Proper packaging can also help prevent waste. Packaging plays an important

part in preventing loss or damage to the packaged-product (contents). Usually, the

energy content and material usage of the product being packaged are much greater than

that of the package. A vital function of the package is to protect the product for its

intended use: if the product is damaged or degraded, its entire energy and material

content may be lost.

Minimization (also source reduction) The mass and volume of packaging (per unit of

contents) can be measured and used as one of the criteria to minimize during the

package design process. Usually reduced packaging also helps minimize costs.

Packaging engineers continue to work toward reduced packging.

Reuse The reuse of a package or component for other purposes is encouraged.

Returnable packaging has long been useful (and economically viable) for closed loop

logistics systems. Inspection, cleaning, repair and recouperage are often needed.

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Recycling Recycling is the reprocessing of materials (pre- and post-consumer) into

new products. Emphasis is focused on recycling the largest primary components of a

package: steel, aluminum, papers, plastics, etc. Small components can be chosen which

are not difficult to separate and do not contaminate recycling operations.

Energy recovery Waste-to-energy and Refuse-derived fuel in approved facilities are

able to make use of the heat available from the packaging components.

Disposal Incineration, and placement in a sanitary landfill are needed for some

materials. Material content should be checked for potential hazards to emissions and ash

from incineration and leachate from landfill. Packages should not be littered.

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PHARMA.PACKAGING MATERIALS

Pharmaceutical packaging has evolved over the years with a number of

innovative concepts. It is necessary that packaging should be done as per the nature of

any drug. Proper packaging provides protection to the drug and also decides the potency

and the shelf life of the medicine. The packaging methods in the pharmaceutical industry

are wide and varied like blister technology, PET bottles, strips, and currently the security

packaging and holograms, have also emerged.

Materials

Nylon/Foil Laminates

Paper/Foil Laminates

Polyester/Foil Laminates

LDPE foils

PVC-coated Paper

Aluminum foil laminates

Tube laminates Sachet/pouch laminates

Blister lidding

Cold formed laminate etc.

Types of pharma packaging

Blister-foils

Blister foils are one of the common packaging of tablets and capsules.Blister packaging helps to protect the medicine from humidity, moisture and other

environmental problems. They help in keeping the medicine fresh. Hard aluminum

alloy is generally used to make the foil. However, the packaging has to undergo

various product and package stability tests so as to make the right package, using

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the right material and manufacturing process required for that particular drug. The

films are given different coatings.

Strip-foils

Strip foils are ideal for tablets and capsules packaging. They are used

for drugs ranging from light sensitive to highly sensitive. They are usually made of

soft , annealed aluminum alloy with colorless LDPE as sealant. These foils are

available in reel form , jumbo roll or cardboard carton.

Cold-forming

Cold-formed laminates are used for packaging of medicines. This type

of packaging is made of aluminum foil. These are designed in peelable, formable

foil structures without cracking or de lamination. The cold forming packages are

available with peelable sealants incorporated into the forming web and are ideal for

dual-formed packages as both top and bottom webs are formed in the package.

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CHILD-RESISTANT PACKAGING

Child-Resistant packaging means packaging that is designed or constructed to

besignificantly difficult for a young child to open, or gain access to the contents of,within areasonable time but not unduly difficult for adults to use properly, but doesnot mean

packaging which all such children cannot open, or obtain the contents of, within a

reasonable time. Child-resistant is not synonymous with child-proof.

Keeping in mind the safety of children the company created child resistant

packaging so that children cant use medication in the absence of adults. They are

compulsory for most of the US Generic Tablets and Capsules and are becoming well

accepted in Europe as well. These packaging are offered in various sizes for the Push

Down and Turn mechanism.

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TAMPER-EVIDENT PACKAGING

Tamper-Evident Packaging (TEP) means packaging that has an indicator or

barrier to entry which, if breached or missing, can reasonably be expected to provide

visible or audible evidence to consumers that tampering may have occurred.

Tamper-Evident Features

The packaging features listed below are considered to be acceptable forms of TEP

provided they are validated.

Whilst these forms of TEP are acceptable, they should not be seen to be exclusive

of other forms of TEP or to preclude technological innovation.

Film Wrappers Transparent

A transparent film with distinctive design is wrapped securely around the entire

product container ensuring the product is completely sealed and a secure tight fit is

achieved. The wrapper must be ripped or broken to gain access to the product.

Sealing of a film wrapper with overlapping end flaps is acceptable only if the ends cannot

be opened and resealed without leaving visible evidence of entry.

Tinted wrappers without a distinctive design are unacceptable because of the possibility

that their material may be readily available as a substitute for the original wrapper.

The use of cellophane wrappers to provide tamper-evidence is not acceptable because of

the possibility that their material may be readily available as a substitute for the original

wrapper and the difficulty in achieving an effective weld seal.

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Blister or Strip Packs

Individual doses (for example, capsules or tablets) are sealed in plastic and/or foil.

Blister or strip pack seals around individual compartments and the strip as a whole, must

be intact and complete. The individual compartment of the pack must be ripped or broken

to gain access to the product.

Bubble Packs

The product and container are sealed in a plastic bubble and mounted in or on a

display ard. The plastic and / or card must be ripped or broken to gain access to the

product. The backing material cannot be separated from the bubble or replaced without

leaving visible evidence of entry. Bubble pack seals must be intact and complete and

sealed all

the way around.

Heat Shrink Bands or Wrappers

Bands or wrappers with a distinctive design are shrunk by heat to tightly seal the

union of the cap and container. The seal must be ripped or broken to gain access to the

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product. The band or wrapper cannot be removed and reapplied without visible damage.

Use of a perforated tear strip can enhance tamper evidence. Cellulose wet shrink seals

are not acceptable because of the reversible nature of these seals. Tinted bands without

a distinctive design are unacceptable because of the possibility that their material may be

readily available as a substitute band or wrapper.

Pouches, Sachets and Form Fill Seal Packs

The product is enclosed in an individual pouch or sachet that must be ripped,

peeled open or broken to gain access to the product. The pouch or sachet must have a

distinctive design. Seals of the pouch or sachet cannot be separated and resealed

without showing visible evidence of entry.

Container Mouth Inner Seals

Paper, thermal plastic, polystyrene foam, plastic film, foil or combinations thereof,

with a distinctive design is sealed to the mouth of a container under the cap. The seal

must be ripped or broken to open the container and gain access to the product. The seals

cannot be removed without showing visible evidence of entry, and once removed, seals

cannot be reapplied without showing visible evidence of entry. Seals must be intact and

complete and sealed all the way around.

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Explanatory Note

Seals applied by heat induction to containers appear to offer a higher degree of

tamper-evidence than those that depend on an adhesive to create the bond. Pressure

sensitive adhesives may not offer adequate evidence of entry.

Tape Seals

Paper, foil or plastic with a distinctive design is sealed over all carton flaps or a

container cap. The seal or pack must be ripped or broken to gain access to the product.

The seals cannot be removed and reapplied, or the carton side-seam breached without

showing visible evidence of entry.

Breakable Caps

The plastic or metal cap has a portion that breaks away on opening and remains

on the neck of the container. The cap cannot be removed or reapplied in its original state.

6.9. Tear-away Caps

The plastic or metal cap has a portion that is torn away in order to allow the

remainder of the cap to be removed to gain access to the product. The tear away portion

must be clearly torn or missing once the package is opened. The cap cannot be removed

or reapplied in its original state.

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Sealed Metal Tubes

The lower end is sealed by folding and / or crimping. That end must not be capable

of being breached by unbending and refolding without visible evidence of entry. The

nozzle is blocked by seal or membrane. The nozzle seal or membrane must be broken or

punctured to gain access to the product. The seals cannot be removed and reapplied

without showing visible evidence of entry.

Sealed Plastic / Laminate Tubes

The lower end of the tube is sealed by heat sealing and crimping. That end must

not be capable of being breached without visible evidence of entry. The nozzle is blocked

by a seal, membrane or twist off top and must be broken or punctured to gain access to

the product.

Cans (Both All-metal and Composite)

The top and bottom of a can must be joined to the can walls in such a manner that

they cannot be pulled apart and reassembled without visible evidence of entry. The can

cannot be reclosed without visible evidence of entry.

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In-built Tamper-Evident Controls

Products such as In-Vitro Diagnostics (IVDs), which are available for use directly

by consumers, may have in-built controls which demonstrate clearly that the product is

unacceptable by showing a test-method failure, avoiding the potential for false results.

Products incorporating such controls, which must be obvious to the user from the

packaging information / instructions when trying to assess the test results, are considered

as having tamper-evident controls, and for the purposes of this Code of Practice are

considered to comply with the requirements without needing additional packaging or

labelling.

Sealed Two-piece Capsules

Two-piece capsules are sealed such that the two halves of the capsule cannot be

separated or rejoined without leaving visible evidence of entry.

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COSMETIC PACKAGING

TECHNIQUES ANDMATERIALS

It is to be noted in modern packing world, the same techniques of packaging

applied by the architecture and automotive industry are also being implemented in the

cosmetics industry. Different materials like metals, plastics, papers and glasses are

bonded for cosmetic packing. Some companies use multi colored holographic effects.

The bright and vibrant colored cosmetic packages are always preferred by the customers.

While women go for bright colored package like orange, the male customer prefers

packaging that is masculine and functional. The halo colors in cosmetic packing are said

to be more feminine. The packaging should also look very attractive if it depicts

cheerfulness and youth. The dark violet glass is recommended to protect the product from

the light and organic contamination. The usage of lacquering has increased over the

years. More interest is shown in glass-like packages among- the customers.

Guidelines -to improve the effectivenessof cosmetic packing

The following guidelines can be followed for cosmetic packaging:

The cosmetic packages for liquid should have sophisticated dispensing services

like pumps.

The packages should depict quality and value.

The packaging should be such that it can effectively act as the spokesman of the

brand.

It should be depict comfort and effectiveness.

The cosmetic packing should not distract or surprise the customer.

The graphics or pictures should play an important role in mass-packaging. An important guideline is that it should not be toxic.

It should be economical.

It should be recyclable.

It should be free of preservatives.

The packaging should be friendly to the environment.

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TYPES OF COSMETIC PACKAGES

Cosmetic, Containers

Containers can be made of plastic or glass. The glass cosmetic containers are

having a huge demand in the market as the detailed decorative designs over the

containers have had a positive impact on the customers. Many manufacturers have

started using bottle designs, embossing and other decorations to attract the customers.

Metal decorations have also become common. The color changing inks with words, logos

create an awareness among the customers. The thermo chromic inks are also used on

the glass containers. The frosted glass roll packaging is being used on containers which

carry lip glosses, perfume, and oils. The plastic cosmetic containers are used for

preserving lotions, oil, shampoos and the other cosmetic products and are recyclable.

These containers can diffuse light. There are separate containers for storing loose

powder and liquid cosmetics. The loose powder are packed in a sifter container or a wide

mouthed jar. The packaging of a body glitter is done with a container which is clear and

not translucent.

Cosmetic Case

A latest introduction in the cosmetics packaging is the cosmeticcase. It is a box type container where different cosmetics are kept. Some

cases are available with a built-in trolley.

Break-Off Top Packaging

This type of package usually consists of a thermoformed chamber

which can be designed to appear like the original package. This packaging is

suitable for liquids and semisolids used in the cosmetic, pharmaceutical and

chemical industries.

Sachets/Pouches

From liquids to semisolid, pastes to pellet-like products, the sachet

or pouch is always a simple and inexpensive way to display your products. It

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is available in single, double sachet strips, die cut sachet, component sachet

variables etc.

Peelable Package

This types of package is sealed with a backing foil, and there is a

flap used for opening the packaging. This packaging is suitable for liquids,

semisolids cosmetic products.

Blister packaging

This is just perfect for retailing. It protects the cosmetic product and

presents it to the consumer.

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AEROSOLS PACKAGING COMPONENTS

ContainersPlastic Coated Glass

Allows level of contents to be seen

Compatible with most formulations

Plastic coating absorbs "neckshock" during crimping and provides barrier to broken

Glass

Poor aesthetic finish / difficult to label / heavy

Used for inhalation aerosols containing dissolved drug

Aluminum

Lightweight and seamless

Can be screen printed, therefore visually appealing

Easy to fill and crimp

Incompatible with some propellants and solvents

Can be anodized or epoxy coated

Opaque

Used for inhalation and topical Aerosols

Three Piece Tinplate

Corrosion inhibitors typically included in formulation

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Not suitable for all products

Incompatible with some propellants and solvents

Visible seams make them less cosmetic appealing

Can be pressurized from the base with compressed gasses

Polyethyleneterephthalate (PET)

Plastic containers under development

Valves

Continuous (used for most topical aerosols)

Product is released as long as pressure is maintained on the actuator. Metered (Used

for all inhalation, & some topical aerosols)

A finite Volume of product is released when the actuator is pressed. No more product is

released unless the actuator is returned to its rest position and repressed

25 -150 l for inhalation aerosols up to 5 ml for topical aerosols

Metered Valve Components

Metering Valve Operation

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PACKAGING MACHINERY

Blister Packaging Machine

Capsule Filling Machine

Pharmaceutical Conveyor

Tube Filling Machine

Shrink Wrapping Machine

Carton Sealing Machine

Cartoners

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Blister Packaging Machine

In pharmaceutical industry Blister Packaging Machines are used for the packing

tablets, capsules, pills and other similar products packing.

The packing process start with the capsules or tablets being loaded into a hopper

and then into a feeder, which in turn can either be linear feeder or a brush boxfeeder depending on the shape of the product and also the material to be used.

Heated rollers in the machine use different plastic films to form blisters that are

subsequently filled with tablets.

Some machines make use of aluminum foil to form blisters. Machines are manufactured according to the size, depth and material used to form

blisters.

After tablets have been inserted in the formed blisters, cavities are heat sealed

using foil.

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Blister Sealing Machines are used to seal filled plastic blister to a piece of coated

carton board, by heat. The blister is kept in the sealing die which has the same

shape as that of the cavity. The cavities are then filled and sealed by a foil suing

heat.

Blister Trimming Machines are used for cutting, trimming the sealed blister or

formed blister packs in individual pieces or bunch.

Automatic Capsule Filling Machine

High Speed Automatic Capsule Filling machines are suitable for filling powders

and pellets. These are versatile machines with several outstanding features both

functional and mechanical.

The machines have capabilities to give an output of 40,000 capsules and 90,000

capsules per hour with high filling accuracy and can accommodate capsule sizes.

Capsule fillers are used to fill hard gelatin and non gelatin capsules with pre

determined quantity of liquids, powders, pellets, tablets.

Most machines conform to the GMP guidelines with various safety features for

maximum operator protection.

Capsules are normally fed into the machine, the filler then align, opens and

accurately fills each capsule and recloses.

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Fillers generate minimum dust with lowest level of product loss. Non-separated,

double loaded capsules and improperly inserted capsules are automatically

rejected by machines to maintain the consistency in the quality of product.

Most capsule fillers are characterized with fast changeover time to accommodate a

variety of capsules in terms of shapes and size.

High Quality Capsule Filling Machine requires minimal maintenance and easy to

clean.

Another important feature is the installation of speed adjusting equipment and

automatic counters ensuring the right quantity of capsules being filled and packed.

Pharmaceutical Ampoules

An ampoule or ampule is a small glass sealed vial which is used to contain orpreserve a fluid. Pharmaceutical ampoules are most commonly used to contain

pharmaceutical hypodermic solutions. They are hermetically sealed by melting the thin

top with an open flame, and are designed with a :

Scoring around the neck

Break ring around the neck

A small cut on the neck

Ampoules are produced from tubing glass. Tubes are inserted in a carrousel and

heat is applied. By applying the right amount of heat and using gravity the shape of the

ampoule is achieved.

Ampoule Filling Machine

Ampoule filling machines are completely cover the product in the inert glass and do

not have a rubber stopper or any other material in direct contact with the drug.

Ampoule filling machines can be used to fill ampoules as well as vials and the

speed varies according to the technology.

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Certain ampoule coding machines apply ring banding to the completed ampoule

tips for accurate identification.

Filling range of these machines is normally between 1ml to 20 ml.

Most ampoule fillers are characterized with fast changeover time to accommodate

a variety of ampoules in terms of shapes and size.

High quality Ampoule filling machines require minimal maintenance and are very

easy to clean.

The installation of speed adjusting equipment and no ampoule no fill capability to

ensure that unfilled ampoules are not packed.

Check weight mechanism of the machine helps to maintain consistency in each

batch.

Sealing is done either by laser sealing system or conventional gas flame.

Liquid Filling Machine

Liquid Filling Machines are specialized machines used to fill bottles, vials,

ampoules and other containers with pre determined quantity of liquids.

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These machines adopt a volumetric piston filling mechanism for smooth liquid

filling.

These machines are easy to operate and fill precise quantity of liquid into

containers.

Filling equipment allow adjustment of different sized bottles without changing parts

and also have 'No Bottle-no fill' mechanism.

Most machines meet the GMP norms and are easy to clean and maintain.

The output of these machines depends whether they are semi or fully automatic.

Liquid Filling machines are generally used in Pharmaceutical and chemical

industries

Types of Liquid Filling Machine

Volumetric Liquid Filling Machine

Volumetric Fillers: Volumetric Liquid Filling Machines are best suited for

filling liquids with low to medium viscosity.

Vacuum Liquid Filling Machine

Vacuum Fillers: Vacuum Liquid Filling Machines are best suited for filling liquids

that are foamy and caustic in nature.

Automatic Liquid Filling Machine

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Automatic anti-pressure liquid filling machine adopting the ways of vacuum filling

to fill all various of overflow products with high accuracy and versatility ensure filling

without leakage, no foam and damaged bottle is no incorporated. Automatic speed

variation adjustment makes operation more convenient and reliable.

Semi Automatic Volumetric Liquid Filling Machines

Semi automatic volumetric liquid filling machines is two head, table top, fully GMP

model used to fill variety of liquids.

Semi automatic volumetric liquid filling machine can be used for different types of

glass, Plastic, Metal containers.

Semi automatic volumetric liquid filling machine works on volumetric principle andis fitted with two syringes on the sides.

The motor and gearbox are covered in a SS cabinet. The desired volume can be

adjusted by increasing or decreasing the eccentricity. Bottles are kept bellow the

nozzles manually.

Output bottles per minute depending on type of liquid and fill size with the help of

three-speed pulley arrangement.

Vial Filling Machine

Vial filling machines are used to fill vials and bottles with liquids, viscous material

and suspensions and powders.

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Vial Filling Machines are mainly used in Pharmaceutical, Ophthalmic, Biotech,

Animal health and related industries.

Automatic vial filling equipment fills injectable liquid into glass vials and thesemachines are made in compliance with GMP guidelines.

Vial Filling Machine comprises of an intake section which loads the vials, which are

then transferred through an intermittent transport section.

These pharmaceutical equipments also have a liquid filling section which fills the

vials with predetermined quantity of liquid or viscous material. Finally the filled and

rubber stopper vials are released and discharged from the machine outlet.

The high technology Vial Filling Machines allow for bottom-up filling of vials with

additional features like 'no-vial-no fill' capability. This is to ensure that no vial goes

to the next section without being filled.

The sensors reject the vials not filled.

Check weight feature enables to maintain consistency in the weight of vials.

Certain filling equipments are so designed as to accommodate rapid size changes

and can be used to fill vials with both liquids and powder.

The output of Vial Filling Machine depends on the process parameters and the

technology of the machine.

Tube Filling Machine

Automatic Tube Filling Machines fill ointment/cream in cylindrical aluminium

collapsible/ lami/ coextruded plastic tubes and close it absolutely safely and

symmetrically.

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No tube - No fill device which makes sure that filling does not take place if tube is

not present at the filling station.

At the orientation station, when the tube is lifted, its presence is checked by a

sensor and this signal is relayed to the filling station. Hence if a tube is not there,

the dosing action does not take place and hence there is no fill.

If the tube is not ejected out by the ejector, the machine stops in order to avoid

damages.

In case of any jamming on the indexing system, to avoid breakages, the load is

sensed by the variable drive through the PLC & the machine stops automatically.

Blow off device and tail cutting arrangements to avoid the paste / cream touching

the sealing portion of the tube.

Over load clutch to protect the indexer and all the related shafts rods etc.

Solid state no tubes no fill device mechanism.

Tube holders are of spring loaded type to take care of any tube diameter variation.

Over load clutch to protect the indexer and all the related shafts rods etc.

Audiovisual Alarm Annunciation System for any abnormal conditions of the

machine.

Comprehensive control panel with all protection features.

Pharmaceutical Machinery: Cartoning And Packaging

Box Strapping Machine

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Box strapping machines are widely used to package all kinds and sizes of boxes

including corrugated boxes and PP boxes.

Semi and fully automatic box strapping machines are equipped with belt and roller

drive and a mechanical tension adjuster for high speed strapping.

Box Strapping Machines allow easy loading and unloading of strapping rolls and

very carefully and efficiently strap various boxes.

The number of boxes strapped, depends on the technical specification and size of

the strapping machine.

Some strapping equipment consists of electro magnetic clutch transmission for

increased strapping speed and has an adjustable cooling time and strap tension

and length for better performance.

Carton Sealing Machine

Carton Sealing Machine, Carton Sealer, Sealing Machine auto carton sealer is

suitable for carton packing, the carton sealing machine can be used for single use or

production line. It adopts adhesive tape to seal carton, economy and fast, easy adjust. It

can finish the sealing both top and bottom. Also you can adjust the height and width for

different cartons. Cartoon Sealing Machines are mainly used in Pharmaceutical, Food &

Beverages, Chemical and Cosmetic Industries.

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Carton sealing machines packaging machinery are used for sealing of cartons,

boxes of various sizes and shapes.

Most Cartoon Sealing machines are equipped with top and bottom double belts for

transporting both heavy as well as light cartons.

The cartons are sealed at the centre with the help of two adjustable guiders and

mobile layers.

V shaped plating head helps to keep the tape straight while sealing and allows for

consistent sealing.

The compact size and easy operations of these machines, makes them usable in

any working space.

Many Carton Sealing Machines can integrate with other packaging devices such

as auto strapping machines for higher output.

The output or the number of cartons sealed depends on the type of automation ofthe machine and its technical specifications.

Shrink Wrapping Machine

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Shrink wrap machines make use of plastic to effectively seal a container or product

by tightly surrounding it.

Vacuum shrink wrapping can prevent bacteria form entering the product and also

protect them form wear and tear during transportation.

The process involves tightening a thermoplastic film around the product and

shrinking it by heat.

It also helps to add strength to the stack, making it dust, water and tamper proof.

Shrink Wrapping machines are used for pharmaceutical packaging.

Certain shrink packaging machines perform the dual function of shrinking and

sealing.

There are various types of shrink wrap machines used according to the product or

material being wrapped.

L-Bar sealers are used to pack products with the help of electricity rather than

heat. Heat guns are used to wrap blister packs.

Vacuum sealers are used to shrink wrap pharmaceutical, medicines.

Suitable for products that require visual inspection of shrink process.

Economical compared to conventional packing.

Multiple packs can be shrunk simultaneously to save time and energy.

Cartoner

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Cartoning Systems are servo driven, feature small footprint design and package

a wide variety of products including blisters, bottles, patches, vials, and syringes.

Ideally suitable for online cartoning of blisters, bottles, vials, vial and ampoule,

bottle and dropper, tubes, etc.

Suitable for tuck-in as well as glued type cartons.

Online leaflet folding and insertion/pre-folded leaflet insertion, batch coding,

embossing and empty carton rejection available.

a survey report on packaging

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