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DATA CATALOGS

Table of Contents

I. NIH Data Discovery Index

• Methodology• Findings• Questions raised

II. Institutional Data Interviews

• Methodology• Findings

III. Outcomes

• Benefits to the library

By: Charles DickensKEVIN READ

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It was the best of times…

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NIH Big Data to Knowledge (BD2K)Facilitating Broad Use of Biomedical Big Data

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NIH Data Discovery Index

Datasets areCITABLE

Datasets areDISCOVERABLE

Datasets areLINKED TO

THE LITERATURE

Datasets arePART OF THE

RESEARCH ECOSYSTEM

NIH Data Sharing Repositories

http://www.nlm.nih.gov/NIHbmic/nih_data_sharing_repositories.html

Searching for NIH-funded unidentified datasets in PubMed and PMC

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113,089

75,441

Remaining articles with unidentified datasets

NIH-funded articles for 2011:

88,592 78,901

Non-PMC Articles

Non-research Articles

Molecular Sequence Data MH

71,913 SI Field

71,680 69,857XML

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PMC Acknowledgements

SI Field

Clinical-Trials.gov

PDB GEO GenBank PubChem RefSeq ISRCTN OMIM0

200

400

600

800

1000

1200

1400

1600

Excluded Articles

8

9

PMC Acknowledgements

PDB

Clinica

lTrials.

gov

GenBan

kGEO

IRD

MGIDIP

Flybase

dbGaPSRA

Worm

BaseM

PD

NURSARGD

ICPSR

VectorB

ase0

100

200

300

400

500

600

700

800

Excluded keywords

10

XML Keyword

GenBan

kPDB

GEOdbSNP

Clinica

lTrials.

govRGD

Flybase SRA DIPdbGaP

Worm

Base MGI

BioGRID

VectorB

ase

Multiple

Keywords

0

100

200

300

400

500

600

Excluded keywords

FlyBase:GeneNetwork:Mouse Genome Informatics:Neuroscience Information

Framework:Rat Genome Database:WormBase:Zebrafish Model

Organism Database

GenBank:PDB

NIH-sponsored data repositories now added to PubMed and PMC search indexes

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383

What category of dataset was used for the research described in the article?

Were live human or animal subjects used in the collection

of the data?

What were the subject(s) of study (from which or whom the data was collected)?

If new dataset(s) were created, what type(s) of data were

collected?

What existing dataset(s) were used? If any?

How many datasets are there in each article?

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Measuring blood pressure in mice

Measuring left hemisphere of brain for growth factor

Staining and imaging

Analysis of images using software

Results

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Average number of datasets per article:

2.92

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% of datasets that use live subjects

54%

Human

51%Animal

49%

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% of new data

87%

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% of data created using pre-existing datasets

13%

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It was the worst of times…

Data Types

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Image Genetic or Genomic

Chemical

Biochemical

Electrical (Elecrophysiological)

Optical – non-image

Behavioral

Computational Simulation or model

Magnetic Resonance – non-image

Structural

Physiological

Questionnaire/Survey

Clinical Measures

Geospatial

INSUFFICIENT

Inter-rater Reliability:

20Total # of datasets (High) Total # of datasets (Low)

0

100

200

300

400

500

600

700

800

Total number of datasets found per 25 ar-ticles

43%

How do we define a data set?

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Dataset

How do we define a data set?

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Datasets

How do we define a data set?

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Datasets

Where in the collection/processing pipeline

should data be described?

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Book of the Second

Understanding institutional data challenges via interviews

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Institutional Data Catalog

• Organize and describe institutional research data

• Promote collaboration within the institution

• Promote a culture of sharing and transparency

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Methodology

• Literature review• ID researchers/PIs using

active grant system• Analyzed datasets in

researcher papers before interviews– Used NIH Data Discovery

Index method

Understand your researchersBASIC SCIENCE RESEARCHERS CLINICAL RESEARCHERS

Data Interviews

Postdocs or student leaves with data

Lack of standards/procedures

Size of data

Messiness/Disconnect between datasets

Too challenging

0 1 2 3 4 5 6 7

Challenges Organizing Data – Basic Science Researchers

Data Interviews

Storage expense

Changes in software

Lack of IT resources

Lack of preservation procedures (readme, plans, postdoc etc.)

Data in multiple storage locations

Storage space

0 1 2 3 4 5 6

Challenges Preserving Data – Basic Science Researchers

Data Interviews

Data quality

Messiness/Disconnect between datasets

Poor data output formats

Can't search data

Data loss

Team miscommunication on who's using data

0 1 2 3 4 5 6

Challenges Organizing Data – Clinical Researchers

Data Interviews

Collaboration only

unknown parties

data repository

general public

primary results only

Do not share

0 1 2 3 4 5 6 7 8 9

Basic ScienceClinical

Experience with Data Sharing

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Only the best of times…How the library benefitted from this exercise

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Identified group to pilot institutional data catalog – Population Health

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Acquired new opportunities for teaching data management

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Developing a lab tool for basic scientists to manage metadata

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Developed a better understanding of researcher needs and challenges

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AcknowledgementsBD2K Project• Lou Knecht, Jim Mork, Kathel Dunn, Betsy Humphreys, Jerry

Sheehan, Mike Huerta, Dr. Donald LindbergAnnotators• Preeti Kochar, Helen Ochej, Susan Schmidt, Melissa Yorks, Shari

Mohary, Olga Printseva, Janice Ward, Oleg Rodionov, Sally Davidson, Jennie Larkin, Peter Lyster, Matt McAuliffe, Greg Farber, Betsy Humphreys, Jerry Sheehan, Mike Huerta, Lou Knecht, Suzy Roy, Swapna Abhyankar, Olivier Bodenreider, Karen Gutzman, Dina Demner Fusman, Laritza Rodriguez, Sonya Shooshan, Samantha Tate, Matthew Simpson, Tracy Edinger, Olubumi Akiwumi, Mary Ann Hantakas, Corinn Sinnott

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kevin.read@nyumc.org Questions?