acoustic transmission in the respiratory system

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Free NTIS catalog lists bibliographic searches of NTIS and 23 other technical databases [01.30.Tt, 43.10.Jk] The 1989 NTIS Published Search TM Master Cataloglists Published Searches, which are bibliographies of up-to-date scientific and technical literature. The Searches contain full abstracts of relevant literature in hun- dreds of different subject areas. They arecompiled from computer searches of 24 leadingU.S. and internationalscientific and technical databases, including the NTIS database. To preparea Published Search,experienced informationspecialists retrieve summaries of reports in a particularsubject area from a specific database (oneof the24 available). The summaries arethenprinted in book- let format for easy reference. In addition, each printed Search booklet lists other, related searches that are available, either from the same database searched, or from one of the other available databases. Thus one Published Search can leadto virtually hundreds and hundreds of reports.or journal articles in a specific fieldand the fields that complement it. EachPublished Search includes: ( 1) a full summary for every research reportor journal articlecited,alongwith the author's name and organiza- tion; (2) aneasy-to-scan title listing for quick browsing; and (3) a thorough subject index. Once a Published Search is purchased, NTIS provides auto- maticnotices when the Search is updated. Published Searches available from NTIS arecompiled from computer searches of the following databases: BBUS BioBusiness BHRA Fluidex;the Fluid Engineering Center COM Computer Database CONF Conference Papers Index EDB EnergyData Base Ei Engineering Information Inc. EiEM Engineering Meetings FSTA Food Science and Technology Abstracts IAA International Aerospace Abstracts INSPEC Information Services for thePhysics and Engineering Communities ISMEC InformationServices in Mechanical Engineering LSC Life Sciences Collection MC Management Contents NTIS National TechnicalInformation Service OCEANIC Oceanic Abstracts PIRA Research Association for the Paper& Board, Printing & Packaging Industries POLLUTION Pollution Abstracts PSTA Packaging Science and Technology Abstracts PTO U.S. PatentBibliographic Database RAPRA The Database of Rubber and Plastics Research Association of Great Britain SPIN Searchable Physics Information Notices SWRA Selected Water Resources Abstracts WSCA World Surface Coating Abstracts WTA World Textile Abstracts To receive a freecopyof the 1989Published Search TM MasterCatalog, write or call NTIS andrequest PR-186/KKF, from NTIS, Springfield, VA 22161, Tel.: (703) 487-4650. sound. Experimental measurements of cavitation thresholds are presented here that elucidate the importance of ultrasound host fluid andnuclei pa- rameters in determining these thresholds. These results are interpreted in the context of an approximate theory,included asan appendix, describing the relationship between these parameters and cavitation threshold pres- sures. An automated experimental apparatus hasbeen developed to deter- minethresholds for cavitation produced in a fluid by short tonebursts of ultrasoundat 0.76, 0.99, and 2.30 MHz. A fluid jet was usedto convect potential cavitation nuclei through the focal region of the insonifying trans- ducer.Potential nucleitested included1-/tm polystyrene spheres, micro- bubbles in the 1- to 10-/tm rangethat are stabilized with humanserum albumin,and wholebloodconstituents. Cavitationwasdetected by a pas- sive acoustical technique that issensitive to sound scattered fromcavitation bubbles. Measurements of the transient cavitation threshold in water, in a fluidof higher viscosity, andin diluted whole blood arepresented. Results from these experiments, whichpermitthe controlof nuclei and hostfluid properties, are compared with the approximate analytical theoryfor the prediction of the onset of cavitation. Thesis advisor: RobertE. Apfel. Micro-mechanics of granular fluid-saturated porous media using the finite element method [43.20.Bi,43.30.Ma, 43.35.Bf,47.55.Mh]-- B. Yavari, Engineering Mechanics Department, The University of Texas at Austin, Austin, TX, 78712, August 1988(Ph.D.).Biot's equations have been used by manyinvestigators to predict the acoustical behavior of fluid-satu- rated porous media. Since thecoefficients in Biot's equations depend onthe microstructure and frequency, an accurate comparison of experimental datawith Biot's equations hasnot yet been established. Bedford et al. [J. Acoust. Soc. Am. 76, 1804-1809 (1984) ] suggested a method to evaluate thedrag and virtualmass coefficients as functions of frequency. Themethod is based on a hypothetical experiment thatrequires solving forthemotion of the fluid in the pores when the pore wallsare subjected to an oscillatory motion. In this dissertation, the finite element method is usedto solvefor the motion of the fluid. The fluid is treated as a nearly incompressible, viscous material. The dragandvirtualmass coefficients aredetermined for several two-and three-dimensional pore spaces. The qualitative behavior of these coefficients is shown to be independent of the pore geometry. It is concluded that thedrag coefficient isinsensitive to thepore geometry, while the virtual mass coefficient is very sensitive to the poregeometry. It is also shown that the results can be expressed in nondimensional forms which permit themto bedetermined for different values of a characteristic dimen- sion of the pore space. Calculations of wave velocity and attenuation of compressional waves based on these coefficients are compared with experi- mental data. [Work supported in part by the Office of Naval Research. ] Thesis advisor: A. Bedford. Copies of the dissertation ( same title) areavailable from U.M.I., 300North Zeeb Road, Ann Arbor, MI 48106. Advanced-degree dissertations in acoustics Editor• note: Abstracts of DoctoralandMaster's degree theses will be welcomed at any time. Please notethat they mustconform to the usuallimit of 200 words, as for archival papers, must bedouble-spaced, andmust bear theappropriate PACSclassification numbers. It would beuseful to provide the nameof the thesis supervisor, and to indicate how a copyof the thesis may be obtained. Thresholds of transient cavitation produced by pulsed ultrasound in a controlled nuclei environment [43.25.Yw, 43.80.Ev]--Christy Katherine Smith Holland,Engineering andApplied Sciences, Yale Universi- ty, Yale Station •t•215 9, NewHaven,CT06520, May 1989 (Ph.D.J. Concern persists overthe potential of damage at the cellular leveldueto transient cavitationproduced by diagnostic and high-intensity therapeutic ultra- Acoustic transmission in the respiratory system [43.80.Jz, 43.80.Qf]•George Robert Wodicka,Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cam- bridge, MA 02139, May 1989(Ph.D.). A model of sound transmission from within the respiratory tract to the chest wall, whichaccounts for the acous- tic coupling throughthe walls of the large airways, wasdeveloped. The respiratory tract isrepresented over the frequency range from 100-600 Hz by an equivalent acoustic circuit. The propagation of sound withinthesur- rounding lungparenchyma is modeled asa cylindrical wave in a homoge- neous mixture of air bubbles in water with associated thermal losses, and the chest wall is considered to bea massive boundary to thewave propagation. Predictedspectral characteristics of transmission includetwo resonance peaks and an overalldecrease in magnitude as frequency increases. The amplitude of sound transmission from mouthto chest wall was measured in adult subjects. The experimental observations agreefavorably with the model predictions. The model suggests that the resonance peaks are deter- 844 J. Acoust. Soc. Am. 86(2), Aug. 1989 0001-4966/89/080844-02500.80 @ 1989 AcousticalSociety of America 844 Redistribution subject to ASA license or copyright; see http://acousticalsociety.org/content/terms. Download to IP: 128.240.225.44 On: Sat, 20 Dec 2014 23:28:40

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Page 1: Acoustic transmission in the respiratory system

Free NTIS catalog lists bibliographic searches of NTIS and 23 other technical databases

[01.30.Tt, 43.10.Jk] The 1989 NTIS Published Search TM Master Catalog lists Published

Searches, which are bibliographies of up-to-date scientific and technical literature. The Searches contain full abstracts of relevant literature in hun-

dreds of different subject areas. They are compiled from computer searches of 24 leading U.S. and international scientific and technical databases, including the NTIS database.

To prepare a Published Search, experienced information specialists retrieve summaries of reports in a particular subject area from a specific database (one of the 24 available). The summaries are then printed in book- let format for easy reference. In addition, each printed Search booklet lists other, related searches that are available, either from the same database searched, or from one of the other available databases. Thus one Published Search can lead to virtually hundreds and hundreds of reports.or journal articles in a specific field and the fields that complement it.

Each Published Search includes: ( 1 ) a full summary for every research report or journal article cited, along with the author's name and organiza- tion; (2) an easy-to-scan title listing for quick browsing; and (3) a thorough subject index. Once a Published Search is purchased, NTIS provides auto- matic notices when the Search is updated.

Published Searches available from NTIS are compiled from computer searches of the following databases:

BBUS BioBusiness

BHRA Fluidex; the Fluid Engineering Center COM Computer Database CONF Conference Papers Index EDB Energy Data Base Ei Engineering Information Inc. EiEM Engineering Meetings FSTA Food Science and Technology Abstracts IAA International Aerospace Abstracts INSPEC Information Services for the Physics and Engineering

Communities

ISMEC Information Services in Mechanical Engineering LSC Life Sciences Collection

MC Management Contents NTIS National Technical Information Service OCEANIC Oceanic Abstracts

PIRA Research Association for the Paper & Board, Printing & Packaging Industries

POLLUTION Pollution Abstracts

PSTA Packaging Science and Technology Abstracts PTO U.S. Patent Bibliographic Database RAPRA The Database of Rubber and Plastics Research

Association of Great Britain

SPIN Searchable Physics Information Notices SWRA Selected Water Resources Abstracts

WSCA World Surface Coating Abstracts WTA World Textile Abstracts

To receive a free copy of the 1989 Published Search TM Master Catalog, write or call NTIS and request PR-186/KKF, from NTIS, Springfield, VA 22161, Tel.: (703) 487-4650.

sound. Experimental measurements of cavitation thresholds are presented here that elucidate the importance of ultrasound host fluid and nuclei pa- rameters in determining these thresholds. These results are interpreted in the context of an approximate theory, included as an appendix, describing the relationship between these parameters and cavitation threshold pres- sures. An automated experimental apparatus has been developed to deter- mine thresholds for cavitation produced in a fluid by short tone bursts of ultrasound at 0.76, 0.99, and 2.30 MHz. A fluid jet was used to convect potential cavitation nuclei through the focal region of the insonifying trans- ducer. Potential nuclei tested included 1-/tm polystyrene spheres, micro- bubbles in the 1- to 10-/tm range that are stabilized with human serum albumin, and whole blood constituents. Cavitation was detected by a pas- sive acoustical technique that is sensitive to sound scattered from cavitation bubbles. Measurements of the transient cavitation threshold in water, in a

fluid of higher viscosity, and in diluted whole blood are presented. Results from these experiments, which permit the control of nuclei and host fluid properties, are compared with the approximate analytical theory for the prediction of the onset of cavitation.

Thesis advisor: Robert E. Apfel.

Micro-mechanics of granular fluid-saturated porous media using the finite element method [43.20.Bi, 43.30.Ma, 43.35.Bf, 47.55.Mh]-- B. Yavari, Engineering Mechanics Department, The University of Texas at Austin, Austin, TX, 78712, August 1988 (Ph.D.). Biot's equations have been used by many investigators to predict the acoustical behavior of fluid-satu- rated porous media. Since the coefficients in Biot's equations depend on the microstructure and frequency, an accurate comparison of experimental data with Biot's equations has not yet been established. Bedford et al. [J. Acoust. Soc. Am. 76, 1804-1809 (1984) ] suggested a method to evaluate the drag and virtual mass coefficients as functions of frequency. The method is based on a hypothetical experiment that requires solving for the motion of the fluid in the pores when the pore walls are subjected to an oscillatory motion. In this dissertation, the finite element method is used to solve for the motion of the fluid. The fluid is treated as a nearly incompressible, viscous material. The drag and virtual mass coefficients are determined for several two- and three-dimensional pore spaces. The qualitative behavior of these coefficients is shown to be independent of the pore geometry. It is concluded that the drag coefficient is insensitive to the pore geometry, while the virtual mass coefficient is very sensitive to the pore geometry. It is also shown that the results can be expressed in nondimensional forms which permit them to be determined for different values of a characteristic dimen- sion of the pore space. Calculations of wave velocity and attenuation of compressional waves based on these coefficients are compared with experi- mental data. [Work supported in part by the Office of Naval Research. ]

Thesis advisor: A. Bedford.

Copies of the dissertation ( same title) are available from U.M.I., 300 North Zeeb Road, Ann Arbor, MI 48106.

Advanced-degree dissertations in acoustics Editor• note: Abstracts of Doctoral and Master's degree theses will be

welcomed at any time. Please note that they must conform to the usual limit of 200 words, as for archival papers, must be double-spaced, and must bear the appropriate PACS classification numbers. It would be useful to provide the name of the thesis supervisor, and to indicate how a copy of the thesis may be obtained.

Thresholds of transient cavitation produced by pulsed ultrasound in a controlled nuclei environment [43.25.Yw, 43.80.Ev]--Christy Katherine Smith Holland, Engineering and Applied Sciences, Yale Universi- ty, Yale Station •t•215 9, New Haven, CT06520, May 1989 (Ph.D.J. Concern persists over the potential of damage at the cellular level due to transient cavitation produced by diagnostic and high-intensity therapeutic ultra-

Acoustic transmission in the respiratory system [43.80.Jz, 43.80.Qf]•George Robert Wodicka, Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cam- bridge, MA 02139, May 1989 (Ph.D.). A model of sound transmission from within the respiratory tract to the chest wall, which accounts for the acous- tic coupling through the walls of the large airways, was developed. The respiratory tract is represented over the frequency range from 100-600 Hz by an equivalent acoustic circuit. The propagation of sound within the sur- rounding lung parenchyma is modeled as a cylindrical wave in a homoge- neous mixture of air bubbles in water with associated thermal losses, and the chest wall is considered to be a massive boundary to the wave propagation. Predicted spectral characteristics of transmission include two resonance peaks and an overall decrease in magnitude as frequency increases. The amplitude of sound transmission from mouth to chest wall was measured in adult subjects. The experimental observations agree favorably with the model predictions. The model suggests that the resonance peaks are deter-

844 J. Acoust. Soc. Am. 86(2), Aug. 1989 0001-4966/89/080844-02500.80 @ 1989 Acoustical Society of America 844

Redistribution subject to ASA license or copyright; see http://acousticalsociety.org/content/terms. Download to IP: 128.240.225.44 On: Sat, 20 Dec 2014 23:28:40

Page 2: Acoustic transmission in the respiratory system

mined by the properties of the respiratory tract and that the decreased amplitude of transmission at higher frequencies can be largely attributed to the absorption of sound in the surrounding lung parenchyma. The model provides a theoretical framework for further investigation into the effects of structural changes on sound transmission in both health and disease.

Thesis advisors: Daniel C. Shannon, Kenneth N. Stevens.

Sound propagation under the Arctic ice canopy [43.30.Ma]--David Glen Wegmann, Naval Postgraduate School, Monterey, C•4 93943, M.S., Engrg. •4coustics, M. $., Systems Technology, March 1989. Propagation in a shallow-water waveguide, covered by a layer of"ice," was studied in a lO- rn-long, 19-cm-deep laboratory facility that models both the scale and the

physical properties of the Arctic. Smooth ice measurements were compared with predictions of the Naval Research Laboratory computer model KEN, which includes the effects of elastic layers. Although the ice canopy thickness is only a small fraction of a wavelength, the sound field is distin- guishable from the usual Pekeris waveguide (no ice cover) behavior by the evidence of seismic-type plate modes. The observed effects are related to the stimulation of ice head waves, which has been reported previously for deep water regions [J. Acoust. $oc. Am. 83, 1794 (1988) and $uppl. 1 82, $31 (1987) ]. The autoregressive and Prony spectral estimation techniques were demonstrated to be effective in identifying the acoustic modes, but they were not as suitable as Fourier techniques for describing the mode coupling caused by a rough ice cover.

Thesis advisor: H. Medwin.

845 J. Acoust. Soc. Am., Vol. 86, No. 2, August 1989 Notes and Briefs 845

Redistribution subject to ASA license or copyright; see http://acousticalsociety.org/content/terms. Download to IP: 128.240.225.44 On: Sat, 20 Dec 2014 23:28:40