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Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang Wang, Yinwei Ho, Tinisha McDonald, Tessa L. Holyoake, WenYong Chen, Ravi Bhatia Cancer Cell Volume 21, Issue 2, Pages 266-281 (February 2012) DOI: 10.1016/j.ccr.2011.12.020 Copyright © 2012 Elsevier Inc. Terms and Conditions

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Page 1: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang

Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib 

Ling Li, Lisheng Wang, Liang Li, Zhiqiang Wang, Yinwei Ho, Tinisha McDonald, Tessa L. Holyoake, WenYong Chen, Ravi Bhatia  

Cancer Cell Volume 21, Issue 2, Pages 266-281 (February 2012)

DOI: 10.1016/j.ccr.2011.12.020

Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 2: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang

Figure 1

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 3: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang

Figure 2

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 4: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang

Figure 3

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 5: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang

Figure 4

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 6: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang

Figure 5

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 7: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang

Figure 6

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 8: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang

Figure 7

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 9: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang

Figure 8

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 10: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

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