active pharmaceutical ingredients portfolio

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Active Pharmaceutical Ingredients Quality Building on our unique skills in fermentation, synthesis and bio-catalysis we provide high quality pharmaceuticals based on our fully integrated vertical global API manufacturing capabilities. For us Quality means more than just cGMP compliance. We have a comprehensive set of Safety, Health and Environment (SHE) policies which we apply globally not only to ourselves but also to our manufacturing partners. On the API side this is supported by our membership in the Together for Sustainability initiative. Combining these standards with our unique technology platform allows us to provide the world with life-saving medicines in a sustainable and responsible way. Reliability We are the reliable, long-term partner in our industry. We deliver the right solutions at the right time, building longterm relationships with our marketing partners to our mutual benefit. For us reliability means that we can reassure our customers of the origin and traceability of all of our products, as well as the way they have been processed and manufactured. Our production is supported by multiple plants across the globe and by operations in each of our regions. All our sites meet and oſten exceed the highest local and international standards. Sustainability We achieve sustainability by pursuing economic performance, environmental quality and social responsibility. In other words, we seek to create value in the three dimensions of People, Planet and Profit. We are pioneers of the most eco-friendly technologies and production processes for sustainable APIs, such as our unique enzymatic technology used to manufacture our Sustainable Antibiotics, proven by more than 500 patented innovations in green technology. Contact and information For more information, please visit www.dsm-sinochem.com or e-mail [email protected] or contact us at one of the addresses below: Singapore (HQ) [email protected] Europe & America Delft, The Netherlands [email protected] China Beijing, P.R. China [email protected] Asia Pacific / Middle East / Africa Gurgaon, India [email protected] Mexico & Latin America Ramos Arizpe, Mexico [email protected] Copyright © 2015 DSM Sinochem Pharmaceuticals. All rights reserved. Although diligent care has been used to ensure that the information provided herein is accurate, nothing contained herein can be construed to imply any representation or warranty as to the accuracy, currency or completeness of this information nor can it be construed to imply any other representation or warranty of any kind, including the implied warranties of merchantability, fitness for a particular purpose or non-infringement. The content of this document is subject to change without further notice. Please contact us for the latest version of this document or further information. Product offers are explicitly not made in respect of those jurisdictions where valid third party patent rights related to such products are in force. In such jurisdictions the advertised products are only offered for regulatory purposes insofar allowed under local provisions like the Bolar provisions in the US and 2004/27/EC in Europe. VAPIPL092015

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Page 1: Active Pharmaceutical Ingredients Portfolio

Active Pharmaceutical Ingredients

QualityBuilding on our unique skills in fermentation, synthesis and bio-catalysis we provide high quality pharmaceuticals based on our fully integrated vertical global API manufacturing capabilities. For us Quality means more than just cGMP compliance. We have a comprehensive set of Safety, Health and Environment (SHE) policies which we apply globally not only to ourselves but also to our manufacturing partners. On the API side this is supported by our membership in the Together for Sustainability initiative. Combining these standards with our unique technology platform allows us to provide the world with life-saving medicines in a sustainable and responsible way.

ReliabilityWe are the reliable, long-term partner in our industry. We deliver the right solutions at the right time, building longterm relationships with our marketing partners to our mutual benefit. For us reliability means that we can reassure our customers of the origin and traceability of all of our products, as well as the way they have been processed and manufactured. Our production is supported by multiple plants across the globe and by operations in each of our regions. All our sites meet and often exceed the highest local and international standards.

SustainabilityWe achieve sustainability by pursuing economic performance, environmental quality and social responsibility. In other words, we seek to create value in the three dimensions of People, Planet and Profit. We are pioneers of the most eco-friendly technologies and production processes for sustainable APIs, such as our unique enzymatic technology used to manufacture our Sustainable Antibiotics, proven by more than 500 patented innovations in green technology.

Contact and informationFor more information, please visitwww.dsm-sinochem.com or e-mail [email protected] or contact us at one of the addresses below:

Singapore (HQ) [email protected]

Europe & America Delft, The Netherlands [email protected]

China Beijing, P.R. China [email protected]

Asia Pacific / Middle East / Africa Gurgaon, India [email protected]

Mexico & Latin America Ramos Arizpe, Mexico [email protected]

Copyright © 2015 DSM Sinochem Pharmaceuticals. All rights reserved.Although diligent care has been used to ensure that the information provided herein is accurate, nothing contained herein can be construed to imply any representation or warranty as to the accuracy, currency or completeness of this information nor can it be construed to imply any other representation or warranty of any kind, including the implied warranties of merchantability, fitness for a particular purpose or non-infringement. The content of this document is subject to change without further notice. Please contact us for the latest version of this document or further information.Product offers are explicitly not made in respect of those jurisdictions where valid third party patent rights related to such products are in force. In such jurisdictions the advertised products are only offered for regulatory purposes insofar allowed under local provisions like the Bolar provisions in the US and 2004/27/EC in Europe. VAPIPL092015

Page 2: Active Pharmaceutical Ingredients Portfolio

Our Active Pharmaceutical Ingredients Portfolio

PenicillinPenicillin G potassium, non-sterilePenicillin G procaine

Beta-lactam Intermediates6-amino-penicillanic acid (6-APA)7-amino-deacetoxycephalosporanic acid (7-ADCA)

Semi-Synthetic PenicillinsPurimox® Powder (Amoxicilline Trihydrate, powder)

Purimox® Powder Extra Dry (Amoxicilline Trihydrate, powder extra dry)

Purimox® Powder grade C (Amoxicilline Trihydrate, powder grade C)

Purimox® Powder grade E (Amoxicilline Trihydrate, powder grade E)

Purimox® Compacted DC (Amoxicilline Trihydrate, compacted for direct compression)

Purimox® Compacted grade A (Amoxicilline Trihydrate, compacted grade A)

Purimox® Compacted grade A (Amoxicilline Trihydrate, compacted grade A extra dry)

Purimox® Compacted grade P (Amoxicilline Trihydrate, compacted grade P)

Purimox® Fine (Amoxicilline Trihydrate, fine powder)

Puricillin® Powder (Ampicillin Trihydrate, powder)

Puricillin® Compacted grade A (Ampicillin Trihydrate, compacted)

IsoxazolesCloxacillin Sodium Compacted Cloxacillin Sodium PowderDicloxacillin Sodium Compacted Flucloxacillin Sodium CompactedFlucloxacillin Sodium PowderOxacillin Sodium Monohydrate Compacted

Semi-Synthetic CephalosporinsPuridrox® Compacted (Cefadroxil Monohydrate, compacted)

Puridrox® Powder (Cefadroxil Monohydrate, powder)

Purilex® Compacted (Cephalexin Monohydrate, compacted)

Purilex® Powder (Cephalexin Monohydrate, powder)

Puridin® Compacted (Cefradine, compacted)

Puridin® Powder (Cefradine, powder)

Puriclor® Powder (Cefaclor, powder)

StatinsAtorvastatin (Atorvastatin calcium trihydrate, micronized)

RosuvastatinPitavastatin*

Anti-FungalsNystatin Powder Nystatin MicronizedNystatin MycelliumCaspofunginMicafungin*Anidulafungin*

* Under development

100% pure & greenFulfilling our duty to protect end users and the environment is something we take very seriously. We have reduced our waste products and greenhouse gas emissions significantly in recent years. Today, we are proud that PureActives® are the world’s purest and most environmentally friendly produced APIs and Drug Products.

Head officeSales officeManufacturing siteR & D site

DSM Sinochem PharmaceuticalsWe are a B2B provider of Active Pharmaceutical Ingredients and generic Drug Products. What sets DSM Sinochem Pharmaceuticals (DSP) apart is our full backward integration and control of our supply chain. We have the advantage of using our own high quality APIs, the PureActives®, in our beta-lactam and statin products, which deliver unique quality and performance in the finished dosage formulation.

Peace of mind On the basis of our unique APIs, we offer our marketing partners a one-stop-shop solution for worry-free generic Drug Products. Based on our vertically integrated production capabilities and paired with our extensive regulatory know-how, doing business with DSP enables you to focus on what truly counts: your business and your customers.

Founded in 1869, DSP looks back at over 140 years of innovation, from fermentation and microbiology in the late 1800s, over penicillin production development in the 1940s, the enzymatic revolution in antibiotic production in the 2000s to new state-of-the-art formulations for generic pharmaceuticals today.

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