addressing disparities in tobacco use & cessation ... · pharmaceutical nicotine replacement...

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Addressing Disparities in Tobacco Use & Cessation: Challenges and Opportunities Jacqui Drope Managing Director Global Cancer Prevention November 2016

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Page 1: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

Addressing Disparities in Tobacco Use & Cessation:

Challenges and Opportunities

Jacqui Drope Managing Director

Global Cancer Prevention

November 2016

Page 2: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

The ACS Center for Tobacco Control: Fighting Disparities

• The Center’s overarching priority is to combat tobacco-related disparities in communities suffering from disproportionately higher tobacco use rates and disproportionate incidence of tobacco-caused morbidity and mortality, such as:

• Low socioeconomic status (SES) • Behavioral and substance abuse disorders • Lesbian, gay, bisexual, and transgender (LGBT) • Racial/ethnic minorities • Homeless

Page 3: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

Benefits of Cessation

10 years of life gained back

6 years of life gained back

4 years of life gained back

QUIT BY AGE

50

QUIT BY AGE

60

QUIT BY AGE

40

Page 4: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

Smokers Want to Quit

• 70% of smokers want to quit

• Fewer than 5% of those who try to quit smoking succeed

Page 5: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

Smoking Among Vulnerable Groups

• High prevalence of combustible tobacco use among vulnerable populations

• Low quit rates

• Need to consider less harmful options and new products to enhance long-term cessation success

Page 6: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

Three Populations Smoke at Highest Rates in U.S.

• The poor (>8 million smokers below poverty level)

• The least educated (>22 million smokers with a high school education, or less)

• Those with co-morbid mental health or addictive disorders smoke 40% of all cigarettes

Page 7: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

Pharmaceutical Nicotine Replacement Therapies: Benefits

• Safe to use

• Use of NRT approximately doubles the likelihood of quitting

• Use of a combination of NRT products has been shown to increase cessation rates compared to use of a single product

Page 8: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

NRT: Disadvantages

• Slow nicotine delivery

• Cost considerations • Misconceptions about health risks

• Developed to be cessation aids rather

than long-term alternatives to smoking

• Strict product regulation

• Lack of wide availability

• Questions about long-term effectiveness

Page 9: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

Smokeless Tobacco

• Used around the world in a wide variety of forms

• Carcinogenic and chemical compounds vary considerably depending on the type of product and manufacturing process

• Low nitrosamine smokeless tobacco products less harmful compared to conventional cigarettes

Page 10: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

Smokeless Tobacco: Swedish Style Snus

• Sweden is the world leader in

reducing smoking prevalence and smoking-related mortality and morbidity

• Research does not support the belief that widespread use of snus or smokeless tobacco is a gateway to smoking among youth

Page 11: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

Electronic Nicotine Delivery Systems (ENDS)

• Devices that do not burn or use tobacco leaves

• Some contain nicotine; some do not

• The main constituents of the solution, in addition to nicotine when nicotine is present, are propylene glycol and flavouring agents

• ENDS solutions and emissions contain other chemicals, some of them considered to be toxicants

Page 12: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

ENDS Efficacy for Cessation?

Page 13: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

Continuum of Risk

Source: Nutt, DJ et al (2014). Estimating the harms of nicotine-containing products using the MCDA approach. Eur Addict Res, 20, 218-225

Page 14: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

Synthesis

• NRTs are safe alternatives to smoking but have led to limited

long-term success in cessation

• Evidence supports that ENDS are less harmful than combustible tobacco

• Smoking marginalized to vulnerable populations who have a

difficult time quitting or are unwilling to quit

• Majority of smokers will likely continue combustibles without acceptable less harmful alternatives

• Continuum of risk associated with nicotine-containing products

• We need to figure out how best to start communicating this

continuum better so that smokers make informed decisions

Page 15: Addressing Disparities in Tobacco Use & Cessation ... · Pharmaceutical Nicotine Replacement Therapies: Benefits • Safe to use • Use of NRT approximately doubles ... • Developed

Contact Us

ACS Center for Tobacco Control [email protected]

Cliff Douglas, J.D. Vice President, Tobacco Control Director, Center for Tobacco Control American Cancer Society [email protected]

Jacqui Drope Managing Director, Global Cancer Prevention and Early Detection American Cancer Society [email protected]