3D Blood Brain Barrier (BBB) Model 3D Cerebral Cortical Model3D Brain Models

Primary neurons and astrocytes maintaindirect cell-cell interactions and formfunctional synapses throughout the spheroids(Cat. #SP3D-1520 & #3D-1520).

Primary HUVEC, human brain vascularpericytes, and astrocytes are co-cultured torecapitulate the intracellular interactions atthe BBB (Cat. #SP3D-8738 & #3D-8738).

3D Liver Models 3D Liver Fibrogenesis-Angiogenesis Model

3D Liver Fibrosis Model

Primary human hepatic stellate-endothelialcell co-culture spheroids can be used toinvestigate the link between fibrosis andangiogenesis (Cat. #SP3D-5000 & #3D-5000).

Primary human hepatocytes and hepaticstellate cells are co-cultured to study cellularcrosstalk in the liver or to better maintainhepatocyte function (Cat. #SP3D-5300).

3D Bone Models 3D Osteogenesis-Angiogenesis

Coupling Spheroid3D Osteoblast Spheroid

1610 Faraday Ave,Carlsbad, CA 92008info@sciencellonline.com

Toll-free (877) 602-8549Fax (760) 602-8575Products are for research purposes only

Osteoblasts grown in ScienCell’s 3D culturemaintain their functionality and have elevatedexpression levels of osteogenic genes (Cat.#SP3D-4650 & #3D-4650).

PDGF-R-β

GFAP

DAPI VWF

Merge

ZO1 Merge

Merge

Merge

DAPI

DAPI

DAPI

β-tubulin III

GFAP

SYN1

DAPI

DAPI

DAPI

Merge

Merge

Merge

ALB

CK18DAPI

DAPI

Merge

Merge

VWF

VimentinDAPI

DAPI

Merge

Merge

SMADAPI Merge

Primary human osteoblasts and endothelialcells are co-cultured to mimic complexcellular interactions in bone tissue (Cat.#SP3D-8748 & #3D-8748).

www.sciencellonline.com

Advance Your Research with ScienCell’s 3D Models

24 h 48 h

CD31DAPI Merge

Aft

er t

haw

ing

Aft

er th

awin

g

3D Blood Brain Barrier (BBB) Model 3D Cerebral Cortical Model3D Brain Models

Primary neurons and astrocytes maintaindirect cell-cell interactions and formfunctional synapses throughout the spheroids(Cat. #SP3D-1520).

Primary HUVEC, human brain vascularpericytes, and astrocytes are co-cultured torecapitulate the intracellular interactions atBBB (Cat. #SP3D-8738).

3D Liver Models 3D Liver Fibrogenesis-Angiogenesis Model3D Liver Fibrosis Model

Primary human hepatic stellate-endothelialcell co-culture spheroids can be used toinvestigate the link between fibrosis andangiogenesis (Cat. #SP3D-5000).

Primary human hepatocytes and hepaticstellate cells are co-cultured to study cellularcrosstalk in the liver or to better maintainhepatocyte function (Cat. #SP3D-5300).

3D Bone Models 3D Osteogenesis-Angiogenesis

Coupling Spheroid 3D Osteoblast Spheroid

Advance Your Research with ScienCell’s 3D Models

1610 Faraday Ave,Carlsbad, CA 92008info@sciencellonline.com

Toll-free (877) 602-8549Fax (760) 602-8575For research use only www.sciencellonline.com

Osteoblasts grown in ScienCell’s 3D culturemaintain their functionality and have elevatedexpression levels of osteogenic genes (Cat.#SP3D-4650).

PDGF-R-β

GFAP

DAPI VWF

Merge

ZO1 Merge

Merge

Merge

DAPI

DAPI

DAPI

β-tubulin III

GFAP

SYN1

DAPI

DAPI

DAPI

Merge

Merge

Merge

ALB

CK18DAPI

DAPI

Merge

Merge

VWF

VimentinDAPI

DAPI

Merge

Merge

SMADAPI Merge

Primary human osteoblasts and endothelialcells are co-cultured to mimic complexcellular interactions in bone tissue (Cat.#SP3D-8748).

24 h 48 h

CD31DAPI Merge

Afte

r tha

win

g

Afte

r tha

win

g 24 h 48 h

3D Blood Brain Barrier (BBB) Model 3D Cerebral Cortical Model3D Brain Models

Primary neurons and astrocytes maintaindirect cell-cell interactions and formfunctional synapses throughout the spheroids(Cat. #SP3D-1520).

Primary HUVEC, human brain vascularpericytes, and astrocytes are co-cultured torecapitulate the intracellular interactions atBBB (Cat. #SP3D-8738).

3D Liver Models 3D Liver Fibrogenesis-Angiogenesis Model3D Liver Fibrosis Model

Primary human hepatic stellate-endothelialcell co-culture spheroids can be used toinvestigate the link between fibrosis andangiogenesis (Cat. #SP3D-5000).

Primary human hepatocytes and hepaticstellate cells are co-cultured to study cellularcrosstalk in the liver or to better maintainhepatocyte function (Cat. #SP3D-5300).

3D Bone Models 3D Osteogenesis-Angiogenesis

Coupling Spheroid 3D Osteoblast Spheroid

Advance Your Research with ScienCell’s 3D Models

1610 Faraday Ave,Carlsbad, CA 92008info@sciencellonline.com

Toll-free (877) 602-8549Fax (760) 602-8575For research use only www.sciencellonline.com

Osteoblasts grown in ScienCell’s 3D culturemaintain their functionality and have elevatedexpression levels of osteogenic genes (Cat.#SP3D-4650).

PDGF-R-β

GFAP

DAPI VWF

Merge

ZO1 Merge

Merge

Merge

DAPI

DAPI

DAPI

β-tubulin III

GFAP

SYN1

DAPI

DAPI

DAPI

Merge

Merge

Merge

ALB

CK18DAPI

DAPI

Merge

Merge

VWF

VimentinDAPI

DAPI

Merge

Merge

SMADAPI Merge

Primary human osteoblasts and endothelialcells are co-cultured to mimic complexcellular interactions in bone tissue (Cat.#SP3D-8748).

24 h 48 h

CD31DAPI Merge

Afte

r tha

win

g

Afte

r tha

win

g 24 h 48 h

3D Cell Culture ProductsScienCell’s

Product Name Cat # Cat #

3D Blood Brain Barrier SpheroidsIncludes primary HUVECs, human brain vascular pericytes and astrocytes

SP3D-8738 3D-8738

3D Cerebral Cortical SpheroidsCo-cultures of primary human neurons and astrocytes

SP3D-1520 3D-1520

3D Hepatocyte-Stellate Cell SpheroidsIdeal for studying liver function and diseases such as liver fibrosis

SP3D-5300 N/A

3D Hepatic Stellate-Endothelial Cell SpheroidsDesigned for studying liver fibrogenesis and angiogenesis

SP3D-5000 3D-5000

3D Pulmonary Alveolar Epithelial Cell SpheroidsExcellent model for examining alveolar maintenance and repair

SP3D-3200 N/A

3D Osteogenesis-Angiogenesis Coupling SpheroidsDesigned for unraveling the molecular crosstalk between angiogenesis and osteogenesis

SP3D-8748 3D-8748

3D Osteoblast SpheroidsAdvanced model for studying the function of osteoblasts

SP3D-4650 3D-4650

3D Chondrocyte SpheroidsIdeal for studying chondrocyte physiology and degenerative joint disease

SP3D-4600 3D-4600

3D Spheroids Using Primary Cells

Collagen-based 3D Cell Culture Kits

Key Features Innovative: We are the only company to offer Ready-To-Use Spheroids. Simple: No experience in 3D cell culture needed. Uniform: Hundreds of 3D spheroids develop uniformly in each well, enhancing the accuracy of the data. Functional: 3D cell cultures provide more relevant and advanced microenvironments.

Brai

nLu

ngLi

ver

Skel

etal

Ready-To-Use All-Inclusive

Product Name Cat #

3D Embedded Tubule Formation KitDesigned to mimic the angiogenic process using primary HUVECs

8708

3D Endothelial-Pericyte Co-culturing KitCo-cultures of primary HUVECs and human brain vascular pericytes

8728

3D Human Blood Brain Barrier Modeling KitCo-cultures of primary HUVECs, human brain vascular pericytes and astrocytes

8738

3D Renal Tubule Formation KitIn Vitro model to study nephrotoxicity and renal tubule development

3D-4110

Vasc

ular

Kidn

eyBr

ain

ScienCell’s 3D Cell Culture Products

All-Inclusive

PDGF receptor βCD31

VWFGFAP

Cat #8738Cat #3D-8738

VWFGFAP

PDGF receptor βGFAP

09262019