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    ADVANCED IMAGING

    TECHNIQUES

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    The most versatile of advanced imaging techniquesinclude:

    Computed tomography(CT)

    Magnetic resonance imaging(MRI)

    Ultrasonography

    Nuclear medicine.

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    COMPUTED

    TOMOGRAPHY

    In 1972 Godfrey hounfield,an

    engineer,announced the invention

    of revolutionary imaging

    techniques that used image

    reconstruction mathamatics

    developed by Alan cormade in

    1950s & 1960s.

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    Computed

    tomographyscanners

    This form of imaging is called as

    computed tomography,abbreviated as

    CT,Computed tomographic

    scanning,axial tomography &

    computerised transaxial tomography.

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    CT scanner consists of an x-

    ray tube that emits a finelycollimated,fan shaped x-ray

    directed through a patient to

    a series of scintillation

    detectors or ionization

    chambers.These detectorsmeasure the no of photons

    that exit the patient.

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    The intensity of the x-ray beam exiting the body is

    determined by:

    1)The energy of the x-ray tube source.

    2)The distance between the source of x-ray & the

    detector.

    3)The attenuation of beam by materials in object being

    scanned.

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    TECHNIQUE

    Patient would

    lie on a

    stationary

    table while thex-ray source

    rotates one

    cycle around

    them.The

    table would

    move 1-5mm

    for the next

    scan.

    CT scan thatuses this type of

    step &

    shootmovement

    for image

    acquisition are

    called

    incrementalscanners.

    The final image

    set consists of

    series ofoverlapping

    axial

    images,made up

    of right angles

    to the long axis

    of the patients

    body.

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    These two dimensional

    slices are cross-

    sections,typically 1mm

    thick.

    In 1989 CT scannerswere introduced that

    acquire image data in

    helical fashion. In

    helical CT

    scanners,Pitch refers

    to the amount of

    patient movement

    compared with the

    width of the image

    acquired.

    Pitch=Table

    travel per x-ray

    rotations/imagethickness

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    MULTIDETECTORHELICAL CT-

    MDCT,multislice

    ct,multirow CT.With

    this method anywherefrom 4-64 adjacent

    detectors arrays are

    used in conjunction

    with helical CT.

    The time for the x-ray

    tube to make a full

    cycle around thepatients has been

    reduced to as little as

    0.35sec.

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    ELECTRON BEAM CT

    An electron gun generates an electron beam that is focused

    electrostatically on a fixed tungstan target circling halfway

    around the patient.

    Because there are no moving parts an image may be

    acquired in less than 100microsec.This technique is

    primarily used for cardiac imaging to stop heart motion.

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    CT TOMOGRAPHICSCANNER COMPUTEDASSEMBLYThe basic componentsof CT are:

    1.Gantry

    2.Patient supporting

    couch

    3.Computer

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    GANTRY

    The gantry is made up of detector array,patient supporting couch & the x-

    ray tube or source.

    The gantry can be tilted up to 30degree.

    The facility to tilt helps in excluding structure from the scan that maydegrade the final image(eg metallic dental restoration).

    Components of gantry are:

    X-ray detectors

    Detector array

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    X-ray tubeCT scanners use x-ray tubes with rotating anodes.These tubes a high heat

    capicity 8 million heat units.

    Operate at-120-140(kvp)

    Focal spot sizes ranges-0.5-2.0mm.

    Xray beam is collimated before & after the patient.Prepatient collimation

    adjusts patient exposure.Postpatient collimation controls slice thickness.

    Slice thickness is typically between 1 &3mm.

    Thinner slices results in higher spatial resolution & contrast less partial

    volume effect & higher patient dose.

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    DETECTORS

    X-ray beam exiting the patient is captured by an array ofdetectors.

    The detectors are usually gas filled or solid state.

    Gas filled ion chamber detectors are usually made of high

    pressure xenon.

    Gas filled ion chamber respond quickly but only capture about50% of photons.

    Solid state detectors are commonly used they are made up of

    cadmium tungstate

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    IMAGE

    RECONSTRUCTION

    Computer algorithms use these photons counts

    to construct one or more often,many digital

    crossectional images.The ct image is recorded

    and displayed as a matrix of individual blocks

    called voxels(volume elements).Each square of

    the image matrix is a pixel.

    Next an interpolator algorithm is used to

    correct for the helical motion of the scanner

    and to construct planer crossectional from the

    helical information.

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    PATIENT

    SUPPORT COUCH

    The patient support couch helps instabilising the position of the patient

    during ct scan.The couch must be made

    of low molecular weight material such as

    carbon filter to ensure that the path of

    the x ray beam is not altered before or

    after it transverse the patient.

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    COMPUTER

    The rapidly of capturing the image,acquring data,and larger matrix

    size(512 *512) necessitates the use of high speed computers.

    CONTROL CONSOLE

    The control console allows the operator to select the parameters of

    the ct scan and view the image as they are been generated.

    Image is stored in the computer so that it can be manipulated in no.

    of ways(eg. Magnetic tapes or discs).

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    COMPUTED TOMOGRAPHIC IMAGE

    CT number representing tissue density.

    The no. is propotional to the degree to which the materialwith in the voxel has attenuated the xray beam.

    Ct no. also called as hounsfield units range from -1000 to

    +1000.

    An image optimised for viewing bone-a bone window,may

    have a range of 700 units and mean of 5000units.

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    TYPICAL HOUNSFIELD UNITS FOR AIR AND TISSUES

    TISSUE HOUNSFIELD UNITS

    BONE +400-+1000

    SOFT TISSUE +40-+80

    WATER 0

    FAT -60_-100

    LUNG -400_-600

    AIR -1000

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    ARTIFACTS

    Different types of

    artifacts may degrade

    CT images.

    Some are: Partial volumeartifacts

    Beam hardening

    artifacts

    Metal artifacts

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    CONTRASTAGENTS

    Are the substances

    used to improvevisualization of

    structure. CT

    imaging frequencyuses

    iodine,administered

    i/v to enhance soft

    tissue and vascular

    image details.

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    ADVANTAGES

    Multiplaner

    images.

    Greater geometric

    projections.

    Manipulation ofacquired images.

    Soft tissue

    imaging.

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    DISADVANTAGES

    Expensive.

    Patients exposure to

    radiations.

    Production

    of

    artifacts.

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    USES IN DENTISTRY

    Evaluation of presence & extent of clinically suspected pathology in the

    head & neck.

    Detection of extention of disease process into the paranasal sinus,baseof skull& orbit.

    Determination of location,extent & displacement of maxillofacial skeletal

    fractures,including direction of subdural & epidural haematomas.

    Salivary gland imaging.

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    Evaluvation of potential implants sites

    using 3D image.

    Evaluation of components of TMJ.

    CT guided FNAC biopsies.

    Virtual surgeries.

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    NUCLEAR MEDICINE

    Radionuclide imaging uses radioactive atoms or

    molecules that emit gamma rays.

    Radionuclides allow measurement of tissue

    funtions in vivo & provide early marker of

    disease through measurement of biochemical

    changes.

    After the radionuclides are administered in the

    body they distribute according to there chemical

    properties.

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    RADIONUCLITIDES

    The ideal radionuclide has a short half life,emits gamma rays and is capable of binding to a variety of

    pharmaceuticals.Although many gamma emitting isotopes are used in imaging,including

    iodine,gallium,selenium.The most commonly used is Technetium.

    Technetium has a half life of 6hr and emits primarily 140 kiloelectron volt photon.As Tc is injected i/v itgets concentrated in thyroid gland and gastric mucosa.

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    TO IMAGE A BONE

    Tc is typically bound to methylene diphosphonate and a dose of 20 to

    30mlci is injected i/v.immediately after injection the tracer distributes

    intravascularly.

    Images made during this flow phase,the first 60-90sec are called as

    radionuclide angiography.

    In the second,or blood pool phase,the tracer moves quickly into the

    extracellular spaces.

    The third or bone scintigraphy phase,is made 2-3hrs after injection show

    most of the tracer activity in skelton,kidney,and bladder.

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    GAMMASCINTILLSTION

    CAMERA

    Gamma

    sclintillation

    camera alsocalled as anger

    camera are most

    common means

    of forming an

    image.

    These camera

    capture photon

    and convertthem to light

    and then to

    voltage signal.

    These signal is

    constructed to a

    planer imagethat shows the

    distribution of

    the radionuclide

    in the patient.

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    SINGLE

    PHOTON

    EMISSION

    COMPUTED

    TOMOGRAPHY

    SPECT is the

    method of

    acquiring

    tromographic

    slices through

    the patient.

    In this

    techniqueeither a single

    or multiple

    gamma camera

    is rotated

    360degree

    about thepatient.

    Image

    acquisition

    takes about 30-

    45min.

    Tomography

    enhances

    contrast and

    removes

    superimposed

    activity.

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    APPLICATIONS

    Investigate

    abnormal metabolic

    bone activity.helps

    in assessing growthactivity in case of

    condylar hyperplasia

    and presence of

    metabolic lesions.

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    POSITRON EMISSION

    TOMOGRAPHY

    PET is most advanced

    imaging modality in

    nuclear medicine.

    100 times sensitive

    than gamma camera.

    Relies on positron

    emitting radionuclide

    generated in cyclotron.

    Radionuclide used are

    glucose,aminoacid

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    USES

    The PET/CTcombination has

    been helpful in

    staging andtreatment of

    squamous cell

    carcinoma in

    head and neck.

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    PRESENTED

    BY

    SAKEENA

    ASSAD

    ROLL

    NO:75