afex: transformative biotechnology, maximizing global impact

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TRANSFORMATIVE BIOTECHNOLOGY Maximizing Global Impact

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We are spiraling toward a precarious future on a planetary scale, marked by imbalanced trends on four fronts: food, energy, poverty, and the environment. By 2050, 9 billion people will need food and energy sources—and the world’s poorest must have effective ways to avoid shrinking further into abject poverty. Compounding the challenge, all this must happen while reducing our environmental footprint. What if we could upgrade the most abundant organic material on earth to provide a solution for this grand challenge?

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  • TRANSFORMATIVE BIOTECHNOLOGYMaximizing Global Impact

  • We are spiraling toward a precarious future on a planetary scale, marked by imbalanced trends on four fronts: food, energy, poverty, and the environment. By 2050, 9 billion people will need food and energy sourcesand the worlds poorest must have effective ways to avoid shrinking further into abject poverty. Compounding the challenge, all this must happen while reducing our environmental footprint.

    WHAT IF WE COULD UPGRADE THE MOST ABUNDANT ORGANIC MATERIAL ON EARTH TO PROVIDE A SOLUTION FOR THIS GRAND CHALLENGE?

    For every ton of corn, wheat, and rice harvested today, an equal amount of nonedible leaves and stalks, called biomass, is left behind. Locked away within this biomassof which nearly 2 billion tons are produced each year around the worldnature stores a huge supply of currently inaccessible sugars. AFEX elegantly partners with nature, unlocking these sugars and converting biomass into a renewable source of animal feed or biofuels.

    But unlocking the sugars alone doesnt solve the problem: Biomass is lightweight and bulky, making storage and transport difficult and expensive. The AFEX process converts biomass into dense, shippable, grain-like pellets, which can then be efficiently stored and shipped over long distances.

    T H E G R A N D C H A L L E N G E

  • 1AFEX is a game-changing agricultural innovation that sustainably expands our capacity tosupply both food and energy, while reducing our environmental footprint and providingpathways out of poverty.

    Michigan State University (MSU) Professor Bruce Dale invented this technology two decades ago, but it would still be sitting on a laboratory shelf had it not been for a breakthrough innovation at MBI, in 2010. With support from a $4.3 million Department of Energy (DOE)grant, awarded in 2011, MBI scaled the technology 100-fold, from the lab to a one-ton-per-day pilot-scale facility.

    To realize AFEXs full potential, we must design, build, and operate a demonstration-scaleAFEX depot. This pioneer depot will allow us to complete large-scale application testing; develop a design easily replicated in rural communities worldwide; and establish a training facility.

    Once proven at demonstration-scale, market forces will drive the rapid scale-up and widespread replication of the pioneer depot template, enabling a substantial positive impact on the grand challenges four fronts: food, energy, poverty, and the environment.

    A F E X : A T R A N S F O R M A T I V E S O L U T I O N

  • 2Agricultural yields saw an age of significant gains,thanks to Norman Borlaug, Father of the GreenRevolution. Those rates of yield-increase have slowed while intense agricultural practices have taken an environmental toll. Todays rate of food produc-tion will not be enough to feed the planets growing population. Is there another revolution that can herald a new era in agricultural productivity?

    We must produce as much food in the next forty years as we have in the last 8,000 combined.

    Over the next twenty years, the worlds middle class will nearly triple to 5 billion, dramatically increasing demand for animal protein (meat & dairy).

    75% of agricultural land worldwide is used to support animals through crops and pasture. There is not enough land to double food production by simply doubling cultivation.

    FOOD

    Food, Energy, Poverty, & Environmental Trends Out of Balance

    TODAYS TROUBLING TIMES: S P I R A L I N G T O W A R D A P R E C A R I O U S F U T U R E

    Experts agree: We are runningout of time to find sustainablesolutions for the planetsgravest challenges. By 2050,9 billion people will need foodand energy sourcesand theworlds poorest must findeffective ways to avoid shrinking further into abject poverty. This alarming snapshot reflects our current capacity to meet projected demands for food and energy. Compounding the challenge even further, we must simultaneously reduce our environmental footprint and addressrural poverty. We must bring these factors into better balance to ensure a prosperous and sustainable future.

    3

    Accessible energy is vital to health, quality of life,and security in every nation; can we continue todepend on fossil resources alone? We may not liketo think about it, but the cars we rely on are a major component of our energy demands. Atmo-spheric greenhouse gases hit record levels in 2013. The laws of physics are non-negotiable, World Meteorological Organization Secretary-General Michel Jarraud said recently. We are running out of time.

    Currently, about 21.3 billion tons of CO2 are generated per year from burning fossil fuels; worldwide, transport continues to be the fastest-growing CO2 emitter.

    By 2050, there will be over 3 billion cars worldwide, triple the current 1 billion.

    Oil consumption hit a record 33 billion barrels per year in 2013.

    ENERGY

    The Lake Erie algae blooms that hit in 2014costing taxpayers millions and cutting off the water supply for half a million in Toledo, Ohioserved as another wake-up call about the need for better conservation practices to stem the tide of agricultural runoff and soil erosion. News outlets showed drinking glasses filled with green slush; the public learned about microcystin, the toxin that induces vomiting and liver damage.

    About half the lakes in Asia and North America are starved of oxygen due to fertilizer runoff, destroying aquatic ecosystems.

    Nearly 1/3 of the worlds arable land has been eroded over the last 40 years and loss continues at a rate of more than 10 million hectares a year.

    If current trends continue, 10 million square kilo-meters of forest and grasslandabout the size of Canadawill be converted to agriculture by 2050.

    Do you sleep with a roof over your head? Do youhave running water? Shelter, clean water, and heatare luxuries for far too many around the world. At least 80% of people live on less than $10 a day, and some 22,000 children under five die each day due to the ravages of poverty.

    There are nearly 1 billion undernourished people worldwide.

    Three-quarters of the poor live in rural areas, and they overwhelmingly rely on agriculture for sustenance.

    The productivity of dairy cattle in developing nations is 1/10th of that in developed nations, depriving rural farmers of much needed income and limiting economic resilience.

    ENVIRONMENTAL FOOTPRINT RURAL POVERTY

    2

    Agricultural yields saw an age of significant gains,thanks to Norman Borlaug, Father of the GreenRevolution. Those rates of yield-increase have slowed while intense agricultural practices have taken an environmental toll. Todays rate of food production will not be enough to feed the planets growing population. Is there another revolution that can herald a new era in agricultural productivity?

    We must produce as much food in the next forty years as we have in the last 8,000 combined.

    Over the next twenty years, the worlds middle class will nearly triple to 5 billion, dramatically increasing demand for animal protein (meat & dairy).

    75% of agricultural land worldwide is used to support animals through crops and pasture. There is not enough land to double food production by simply doubling cultivation.

    FOOD

    Food, Energy, Poverty, & Environmental Trends Out of Balance

    TODAYS TROUBLING TIMES: S P I R A L I N G T O W A R D A P R E C A R I O U S F U T U R E

    Experts agree: We are runningout of time to find sustainablesolutions for the planetsgravest challenges. By 2050,9 billion people will need foodand energy sourcesand theworlds poorest must findeffective ways to avoid shrinking further into abject poverty. This alarming snapshot reflects our current capacity to meet projected demands for food and energy. Compounding the challenge even further, we must simultaneously reduce our environmental footprint and addressrural poverty. We must bring these factors into better balance to ensure a prosperous and sustainable future.

    3

    Accessible energy is vital to health, quality of life,and security in every nation; can we continue todepend on fossil resources alone? We may not liketo think about it, but the cars we rely on are a major component of our energy demands. Atmo-spheric greenhouse gases hit record levels in 2013. The laws of physics are non-negotiable, World Meteorological Organization Secretary-General Michel Jarraud said recently. We are running out of time.

    Currently, about 21.3 billion tons of CO2 are generated per year from burning fossil fuels; worldwide, transport continues to be the fastest-growing CO2 emitter.

    By 2050, there will be over 3 billion cars worldwide, triple the current 1 billion.

    Oil consumption hit a record 33 billion barrels per year in 2013.

    ENERGY

    The Lake Erie algae blooms that hit in 2014costing taxpayers millions and cutting off the water supply for half a million in Toledo, Ohioserved as another wake-up call about the need for better conservation practices to stem the tide of agricultural runoff and soil erosion. News outlets showed drinking glasses filled with green slush; the public learned about microcystin, the toxin that induces vomiting and liver damage.

    About half the lakes in Asia and North America are starved of oxygen due to fertilizer runoff, destroying aquatic ecosystems.

    Nearly 1/3 of the worlds arable land has been eroded over the last 40 years and loss continues at a rate of more than 10 million hectares a year.

    If current trends continue, 10 million square kilo-meters of forest and grasslandabout the size of Canadawill be converted to agriculture by 2050.

    Do you sleep with a roof over your head? Do youhave running water? Shelter, clean water, and heatare luxuries for far too many around the world. At least 80% of people live on less than $10 a day, and some 22,000 children under five die each day due to the ravages of poverty.

    There are nearly 1 billion undernourished people worldwide.

    Three-quarters of the poor live in rural areas, and they overwhelmingly rely on agriculture for sustenance.

    The productivity of dairy cattle in developing nations is 1/10th of that in developed nations, depriving rural farmers of much needed income and limiting economic resilience.

    ENVIRONMENTAL FOOTPRINT RURAL POVERTY

  • 3Accessible energy is vital to health, quality of life,and security in every nation; can we continue todepend on fossil resources alone? We may not liketo think about it, but the cars we rely on are a major component of our energy demands. Atmo-spheric greenhouse gases hit record levels in 2013. The laws of physics are non-negotiable, World Meteorological Organization Secretary-General Michel Jarraud said recently. We are running out of time.

    Currently, about 21.3 billion tons of CO2 are generated per year from burning fossil fuels; worldwide, transport continues to be the fastest-growing CO2 emitter.

    By 2050, there will be over 3 billion cars worldwide, triple the current 1 billion.

    Oil consumption hit a record 33 billion barrels per year in 2013.

    ENERGY

    The Lake Erie algae blooms that hit in 2014costing taxpayers millions and cutting off the water supply for half a million in Toledo, Ohioserved as another wake-up call about the need for better conservation practices to stem the tide of agricultural runoff and soil erosion. News outlets showed drinking glasses filled with green slush; the public learned about microcystin, the toxin that induces vomiting and liver damage.

    About half the lakes in Asia and North America are starved of oxygen due to fertilizer runoff, destroying aquatic ecosystems.

    Nearly 1/3 of the worlds arable land has been eroded over the last 40 years and loss continues at a rate of more than 10 million hectares a year.

    If current trends continue, 10 million square kilo-meters of forest and grasslandabout the size of Canadawill be converted to agriculture by 2050.

    Do you sleep with a roof over your head? Do youhave running water? Shelter, clean water, and heatare luxuries for far too many around the world. At least 80% of people live on less than $10 a day, and some 22,000 children under five die each day due to the ravages of poverty.

    There are nearly 1 billion undernourished people worldwide.

    Three-quarters of the poor live in rural areas, and they overwhelmingly rely on agriculture for sustenance.

    The productivity of dairy cattle in developing nations is 1/10th of that in developed nations, depriving rural farmers of much needed income and limiting economic resilience.

    ENVIRONMENTAL FOOTPRINT RURAL POVERTY

    2

    Agricultural yields saw an age of significant gains,thanks to Norman Borlaug, Father of the GreenRevolution. Those rates of yield-increase have slowed while intense agricultural practices have taken an environmental toll. Todays rate of food production will not be enough to feed the planets growing population. Is there another revolution that can herald a new era in agricultural productivity?

    We must produce as much food in the next forty years as we have in the last 8,000 combined.

    Over the next twenty years, the worlds middle class will nearly triple to 5 billion, dramatically increasing demand for animal protein (meat & dairy).

    75% of agricultural land worldwide is used to support animals through crops and pasture. There is not enough land to double food production by simply doubling cultivation.

    FOOD

    Food, Energy, Poverty, & Environmental Trends Out of Balance

    TODAYS TROUBLING TIMES: S P I R A L I N G T O W A R D A P R E C A R I O U S F U T U R E

    Experts agree: We are runningout of time to find sustainablesolutions for the planetsgravest challenges. By 2050,9 billion people will need foodand energy sourcesand theworlds poorest must findeffective ways to avoid shrinking further into abject poverty. This alarming snapshot reflects our current capacity to meet projected demands for food and energy. Compounding the challenge even further, we must simultaneously reduce our environmental footprint and addressrural poverty. We must bring these factors into better balance to ensure a prosperous and sustainable future.

    3

    Accessible energy is vital to health, quality of life,and security in every nation; can we continue todepend on fossil resources alone? We may not liketo think about it, but the cars we rely on are a major component of our energy demands. Atmo-spheric greenhouse gases hit record levels in 2013. The laws of physics are non-negotiable, World Meteorological Organization Secretary-General Michel Jarraud said recently. We are running out of time.

    Currently, about 21.3 billion tons of CO2 are generated per year from burning fossil fuels; worldwide, transport continues to be the fastest-growing CO2 emitter.

    By 2050, there will be over 3 billion cars worldwide, triple the current 1 billion.

    Oil consumption hit a record 33 billion barrels per year in 2013.

    ENERGY

    The Lake Erie algae blooms that hit in 2014costing taxpayers millions and cutting off the water supply for half a million in Toledo, Ohioserved as another wake-up call about the need for better conservation practices to stem the tide of agricultural runoff and soil erosion. News outlets showed drinking glasses filled with green slush; the public learned about microcystin, the toxin that induces vomiting and liver damage.

    About half the lakes in Asia and North America are starved of oxygen due to fertilizer runoff, destroying aquatic ecosystems.

    Nearly 1/3 of the worlds arable land has been eroded over the last 40 years and loss continues at a rate of more than 10 million hectares a year.

    If current trends continue, 10 million square kilo-meters of forest and grasslandabout the size of Canadawill be converted to agriculture by 2050.

    Do you sleep with a roof over your head? Do youhave running water? Shelter, clean water, and heatare luxuries for far too many around the world. At least 80% of people live on less than $10 a day, and some 22,000 children under five die each day due to the ravages of poverty.

    There are nearly 1 billion undernourished people worldwide.

    Three-quarters of the poor live in rural areas, and they overwhelmingly rely on agriculture for sustenance.

    The productivity of dairy cattle in developing nations is 1/10th of that in developed nations, depriving rural farmers of much needed income and limiting economic resilience.

    ENVIRONMENTAL FOOTPRINT RURAL POVERTY

  • 44

    Currently, an estimated 35% of global crop productionis fed to animals. AFEX unlocks natures bind onsugar sources inside the crop residue of corn, wheat,and riceas well as perennial grasses. By using cropresiduesof which there are 2 billion tons availableworldwideinstead of grain to feed animals, we canboth expand animal protein production and increasethe supply of grain for direct human nutrition.

    300 million tons of AFEX pellets could replace all grain currently fed to beef and dairy cattle, freeing up enough grain to feed 1 billion people.

    With the combination of AFEX-treated crop residues and grain, each acre of cropland would produce an additional 50% more feed.

    FOOD

    AFEX: BUILDING A LEGACY OF POSITIVE GLOBAL IMPACT

    TOWARD A SUSTAINABLE FUTURE: T R A N S F O R M A T I V E B I O T E C H N O L O G Y

    What if we had the means to take the planets most ample organic materialcellulose, which is found in plants and in the abundant crop residue left over from grain harvestsand convert it into animal feed or biofuels? A game-changing innovation of this kind could foster a blossoming scenario, reflected in this diagram, in which we sustainably expand our capacity to supply both food and energywhile reducing our environmental footprint and providing pathways out of poverty.

    AFEX is a biobased technology that convertscellulose from crop residues into a sustainablesource of cattle feed and biofuels. Bulky andunwieldy crop residues and grasses are convertedinto pellets that are easily stored and transportedanywhere. The conversion takes place in a decentralized system of depots built where crops are grown, allowing the worlds rural poor to earn more for their families. To maximize global and societal impact, AFEX will be made available worldwide on an affordable, accessible basis.

    4

    Currently, an estimated 35% of global crop productionis fed to animals. AFEX unlocks natures bind onsugar sources inside the crop residue of corn, wheat,and riceas well as perennial grasses. By using cropresiduesof which there are 2 billion tons availableworldwideinstead of grain to feed animals, we canboth expand animal protein production and increasethe supply of grain for direct human nutrition.

    300 million tons of AFEX pellets could replace all grain currently fed to beef and dairy cattle, freeing up enough grain to feed 1 billion people.

    With the combination of AFEX-treated crop residues and grain, each acre of cropland would produce an additional 50% more feed.

    FOOD

    AFEX: BUILDING A LEGACY OF POSITIVE GLOBAL IMPACT

    TOWARD A SUSTAINABLE FUTURE: T R A N S F O R M A T I V E B I O T E C H N O L O G Y

    What if we had the means to take the planets most ample organic materialcellulose, which is found in plants and in the abundant crop residue left over from grain harvestsand convert it into animal feed or biofuels? A game-changing innovation of this kind could foster a blossoming scenario, reflected in this diagram, in which we sustainably expand our capacity to supply both food and energywhile reducing our environmental footprint and providing pathways out of poverty.

    AFEX is a biobased technology that convertscellulose from crop residues into a sustainablesource of cattle feed and biofuels. Bulky andunwieldy crop residues and grasses are convertedinto pellets that are easily stored and transportedanywhere. The conversion takes place in a decentralized system of depots built where crops are grown, allowing the worlds rural poor to earn more for their families. To maximize global and societal impact, AFEX will be made available worldwide on an affordable, accessible basis.

    5

    A world-renowned scientist at Michigan StateUniversity discovered a way to liberate the sugars insidecrop residues and grasses, transforming them intoeither cattle feed or into a source of sustainable,renewable fuels. AFEX enters the global market at atime when urgent concerns about the worseningeffects of global warming and competition for fossilresources are compelling experts and concernedcitizens to examine ways to switch to renewable fuels.

    1 billion tons of AFEX pellets could produce enough renewable fuel to power 200 million cars each year.

    Renewable fuels from 1 billion tons of AFEX pellets could eliminate 680 million tons of fossil CO2 per year, equivalent to 9% of total U.S. emissions.

    ENERGY

    Its no secret better conservation practices would helpprevent the type of runoff that sparked Lake Eries algal blooms. Farmerswho are already squeezed financiallyneed more robust financial incentives to implement conservation best practices, like no-till farming, cover crops, and buffer strips. As a hallmark of its versatility as a multifaceted solution, AFEX provides farmers with an economic resource driver to support adoption of conservation best practices.

    Conservation practices such as no-till farming, cover crops, and buffer strips can reduce soil erosion and nutrient run-off by at least 50%.

    Implementing AFEX would provide a key market for crop residues and perennial grasses, thereby generating revenues needed to support the adoption of conservation practices.

    Through a globally accessible, market-oriented modeland a decentralized distribution design relying ondepots built in rural communities, AFEX offers the rare opportunity to make a significant impact in the lives of some of the neediest rural poor. India provides a telling case study in AFEXs potential impact.

    50 million rural families in India own only one or two dairy cattle. Low milk productivity of dairy cattle in developing nations could be improved by substituting AFEX pellets for the untreated crop residues these cattle are typically fed today.

    The annual profit per cow could easily triple as a result of AFEX, and this increased profit from a single cow is sufficient to lift a family of five above the poverty level.

    ENVIRONMENTAL FOOTPRINT RURAL POVERTY

    5

    A world-renowned scientist at Michigan StateUniversity discovered a way to liberate the sugars insidecrop residues and grasses, transforming them intoeither cattle feed or into a source of sustainable,renewable fuels. AFEX enters the global market at atime when urgent concerns about the worseningeffects of global warming and competition for fossilresources are compelling experts and concernedcitizens to examine ways to switch to renewable fuels.

    1 billion tons of AFEX pellets could produce enough renewable fuel to power 200 million cars each year.

    Renewable fuels from 1 billion tons of AFEX pellets could eliminate 680 million tons of fossil CO2 per year, equivalent to 9% of total U.S. emissions.

    ENERGY

    Its no secret better conservation practices would helpprevent the type of runoff that sparked Lake Eries algal blooms. Farmerswho are already squeezed financial-lyneed more robust financial incentives to imple-ment conservation best practices, like no-till farming, cover crops, and buffer strips. As a hallmark of its versatility as a multifaceted solution, AFEX provides farmers with an economic resource driver to support adoption of conservation best practices.

    Conservation practices such as no-till farming, cover crops, and buffer strips can reduce soil erosion and nutrient run-off by at least 50%.

    Implementing AFEX would provide a key market for crop residues and perennial grasses, thereby generating revenues needed to support the adoption of conservation practices.

    Through a globally accessible, market-oriented modeland a decentralized distribution design relying ondepots built in rural communities, AFEX offers the rare opportunity to make a significant impact in the lives of some of the neediest rural poor. India provides a telling case study in AFEXs potential impact.

    50 million rural families in India own only one or two dairy cattle. Low milk productivity of dairy cattle in developing nations could be improved by substituting AFEX pellets for the untreated crop residues these cattle are typically fed today.

    The annual profit per cow could easily triple as a result of AFEX, and this increased profit from a single cow is sufficient to lift a family of five above the poverty level.

    ENVIRONMENTAL FOOTPRINT RURAL POVERTY

    4

    Currently, an estimated 35% of global crop productionis fed to animals. AFEX unlocks natures bind onsugar sources inside the crop residue of corn, wheat,and riceas well as perennial grasses. By using cropresiduesof which there are 2 billion tons availableworldwideinstead of grain to feed animals, we canboth expand animal protein production and increasethe supply of grain for direct human nutrition.

    300 million tons of AFEX pellets could replace all grain currently fed to beef and dairy cattle, freeing up enough grain to feed 1 billion people.

    With the combination of AFEX-treated crop residues and grain, each acre of cropland would produce an additional 50% more feed.

    FOOD

    AFEX: BUILDING A LEGACY OF POSITIVE GLOBAL IMPACT

    TOWARD A SUSTAINABLE FUTURE: T R A N S F O R M A T I V E B I O T E C H N O L O G Y

    What if we had the means to take the planets most ample organic materialcellulose, which is found in plants and in the abundant crop residue left over from grain harvestsand convert it into animal feed or biofuels? A game-changing innovation of this kind could foster a blossoming scenario, reflected in this diagram, in which we sustainably expand our capacity to supply both food and energywhile reducing our environmental footprint and providing pathways out of poverty.

    AFEX is a biobased technology that convertscellulose from crop residues into a sustainablesource of cattle feed and biofuels. Bulky andunwieldy crop residues and grasses are convertedinto pellets that are easily stored and transportedanywhere. The conversion takes place in a decentralized system of depots built where crops are grown, allowing the worlds rural poor to earn more for their families. To maximize global and societal impact, AFEX will be made available worldwide on an affordable, accessible basis.

    5

    A world-renowned scientist at Michigan StateUniversity discovered a way to liberate the sugars insidecrop residues and grasses, transforming them intoeither cattle feed or into a source of sustainable,renewable fuels. AFEX enters the global market at atime when urgent concerns about the worseningeffects of global warming and competition for fossilresources are compelling experts and concernedcitizens to examine ways to switch to renewable fuels.

    1 billion tons of AFEX pellets could produce enough renewable fuel to power 200 million cars each year.

    Renewable fuels from 1 billion tons of AFEX pellets could eliminate 680 million tons of fossil CO2 per year, equivalent to 9% of total U.S. emissions.

    ENERGY

    Its no secret better conservation practices would helpprevent the type of runoff that sparked Lake Eries algal blooms. Farmerswho are already squeezed financiallyneed more robust financial incentives to implement conservation best practices, like no-till farming, cover crops, and buffer strips. As a hallmark of its versatility as a multifaceted solution, AFEX provides farmers with an economic resource driver to support adoption of conservation best practices.

    Conservation practices such as no-till farming, cover crops, and buffer strips can reduce soil erosion and nutrient run-off by at least 50%.

    Implementing AFEX would provide a key market for crop residues and perennial grasses, thereby generating revenues needed to support the adoption of conservation practices.

    Through a globally accessible, market-oriented modeland a decentralized distribution design relying ondepots built in rural communities, AFEX offers the rare opportunity to make a significant impact in the lives of some of the neediest rural poor. India provides a telling case study in AFEXs potential impact.

    50 million rural families in India own only one or two dairy cattle. Low milk productivity of dairy cattle in developing nations could be improved by substituting AFEX pellets for the untreated crop residues these cattle are typically fed today.

    The annual profit per cow could easily triple as a result of AFEX, and this increased profit from a single cow is sufficient to lift a family of five above the poverty level.

    ENVIRONMENTAL FOOTPRINT RURAL POVERTY

  • 54

    Currently, an estimated 35% of global crop productionis fed to animals. AFEX unlocks natures bind onsugar sources inside the crop residue of corn, wheat,and riceas well as perennial grasses. By using cropresiduesof which there are 2 billion tons availableworldwideinstead of grain to feed animals, we canboth expand animal protein production and increasethe supply of grain for direct human nutrition.

    300 million tons of AFEX pellets could replace all grain currently fed to beef and dairy cattle, freeing up enough grain to feed 1 billion people.

    With the combination of AFEX-treated crop residues and grain, each acre of cropland would produce an additional 50% more feed.

    FOOD

    AFEX: BUILDING A LEGACY OF POSITIVE GLOBAL IMPACT

    TOWARD A SUSTAINABLE FUTURE: T R A N S F O R M A T I V E B I O T E C H N O L O G Y

    What if we had the means to take the planets most ample organic materialcellulose, which is found in plants and in the abundant crop residue left over from grain harvestsand convert it into animal feed or biofuels? A game-changing innovation of this kind could foster a blossoming scenario, reflected in this diagram, in which we sustainably expand our capacity to supply both food and energywhile reducing our environmental footprint and providing pathways out of poverty.

    AFEX is a biobased technology that convertscellulose from crop residues into a sustainablesource of cattle feed and biofuels. Bulky andunwieldy crop residues and grasses are convertedinto pellets that are easily stored and transportedanywhere. The conversion takes place in a decentralized system of depots built where crops are grown, allowing the worlds rural poor to earn more for their families. To maximize global and societal impact, AFEX will be made available worldwide on an affordable, accessible basis.

    4

    Currently, an estimated 35% of global crop productionis fed to animals. AFEX unlocks natures bind onsugar sources inside the crop residue of corn, wheat,and riceas well as perennial grasses. By using cropresiduesof which there are 2 billion tons availableworldwideinstead of grain to feed animals, we canboth expand animal protein production and increasethe supply of grain for direct human nutrition.

    300 million tons of AFEX pellets could replace all grain currently fed to beef and dairy cattle, freeing up enough grain to feed 1 billion people.

    With the combination of AFEX-treated crop residues and grain, each acre of cropland would produce an additional 50% more feed.

    FOOD

    AFEX: BUILDING A LEGACY OF POSITIVE GLOBAL IMPACT

    TOWARD A SUSTAINABLE FUTURE: T R A N S F O R M A T I V E B I O T E C H N O L O G Y

    What if we had the means to take the planets most ample organic materialcellulose, which is found in plants and in the abundant crop residue left over from grain harvestsand convert it into animal feed or biofuels? A game-changing innovation of this kind could foster a blossoming scenario, reflected in this diagram, in which we sustainably expand our capacity to supply both food and energywhile reducing our environmental footprint and providing pathways out of poverty.

    AFEX is a biobased technology that convertscellulose from crop residues into a sustainablesource of cattle feed and biofuels. Bulky andunwieldy crop residues and grasses are convertedinto pellets that are easily stored and transportedanywhere. The conversion takes place in a decentralized system of depots built where crops are grown, allowing the worlds rural poor to earn more for their families. To maximize global and societal impact, AFEX will be made available worldwide on an affordable, accessible basis.

    5

    A world-renowned scientist at Michigan StateUniversity discovered a way to liberate the sugars insidecrop residues and grasses, transforming them intoeither cattle feed or into a source of sustainable,renewable fuels. AFEX enters the global market at atime when urgent concerns about the worseningeffects of global warming and competition for fossilresources are compelling experts and concernedcitizens to examine ways to switch to renewable fuels.

    1 billion tons of AFEX pellets could produce enough renewable fuel to power 200 million cars each year.

    Renewable fuels from 1 billion tons of AFEX pellets could eliminate 680 million tons of fossil CO2 per year, equivalent to 9% of total U.S. emissions.

    ENERGY

    Its no secret better conservation practices would helpprevent the type of runoff that sparked Lake Eries algal blooms. Farmerswho are already squeezed financiallyneed more robust financial incentives to implement conservation best practices, like no-till farming, cover crops, and buffer strips. As a hallmark of its versatility as a multifaceted solution, AFEX provides farmers with an economic resource driver to support adoption of conservation best practices.

    Conservation practices such as no-till farming, cover crops, and buffer strips can reduce soil erosion and nutrient run-off by at least 50%.

    Implementing AFEX would provide a key market for crop residues and perennial grasses, thereby generating revenues needed to support the adoption of conservation practices.

    Through a globally accessible, market-oriented modeland a decentralized distribution design relying ondepots built in rural communities, AFEX offers the rare opportunity to make a significant impact in the lives of some of the neediest rural poor. India provides a telling case study in AFEXs potential impact.

    50 million rural families in India own only one or two dairy cattle. Low milk productivity of dairy cattle in developing nations could be improved by substituting AFEX pellets for the untreated crop residues these cattle are typically fed today.

    The annual profit per cow could easily triple as a result of AFEX, and this increased profit from a single cow is sufficient to lift a family of five above the poverty level.

    ENVIRONMENTAL FOOTPRINT RURAL POVERTY

    5

    A world-renowned scientist at Michigan StateUniversity discovered a way to liberate the sugars insidecrop residues and grasses, transforming them intoeither cattle feed or into a source of sustainable,renewable fuels. AFEX enters the global market at atime when urgent concerns about the worseningeffects of global warming and competition for fossilresources are compelling experts and concernedcitizens to examine ways to switch to renewable fuels.

    1 billion tons of AFEX pellets could produce enough renewable fuel to power 200 million cars each year.

    Renewable fuels from 1 billion tons of AFEX pellets could eliminate 680 million tons of fossil CO2 per year, equivalent to 9% of total U.S. emissions.

    ENERGY

    Its no secret better conservation practices would helpprevent the type of runoff that sparked Lake Eries algal blooms. Farmerswho are already squeezed financial-lyneed more robust financial incentives to imple-ment conservation best practices, like no-till farming, cover crops, and buffer strips. As a hallmark of its versatility as a multifaceted solution, AFEX provides farmers with an economic resource driver to support adoption of conservation best practices.

    Conservation practices such as no-till farming, cover crops, and buffer strips can reduce soil erosion and nutrient run-off by at least 50%.

    Implementing AFEX would provide a key market for crop residues and perennial grasses, thereby generating revenues needed to support the adoption of conservation practices.

    Through a globally accessible, market-oriented modeland a decentralized distribution design relying ondepots built in rural communities, AFEX offers the rare opportunity to make a significant impact in the lives of some of the neediest rural poor. India provides a telling case study in AFEXs potential impact.

    50 million rural families in India own only one or two dairy cattle. Low milk productivity of dairy cattle in developing nations could be improved by substituting AFEX pellets for the untreated crop residues these cattle are typically fed today.

    The annual profit per cow could easily triple as a result of AFEX, and this increased profit from a single cow is sufficient to lift a family of five above the poverty level.

    ENVIRONMENTAL FOOTPRINT RURAL POVERTY

    4

    Currently, an estimated 35% of global crop productionis fed to animals. AFEX unlocks natures bind onsugar sources inside the crop residue of corn, wheat,and riceas well as perennial grasses. By using cropresiduesof which there are 2 billion tons availableworldwideinstead of grain to feed animals, we canboth expand animal protein production and increasethe supply of grain for direct human nutrition.

    300 million tons of AFEX pellets could replace all grain currently fed to beef and dairy cattle, freeing up enough grain to feed 1 billion people.

    With the combination of AFEX-treated crop residues and grain, each acre of cropland would produce an additional 50% more feed.

    FOOD

    AFEX: BUILDING A LEGACY OF POSITIVE GLOBAL IMPACT

    TOWARD A SUSTAINABLE FUTURE: T R A N S F O R M A T I V E B I O T E C H N O L O G Y

    What if we had the means to take the planets most ample organic materialcellulose, which is found in plants and in the abundant crop residue left over from grain harvestsand convert it into animal feed or biofuels? A game-changing innovation of this kind could foster a blossoming scenario, reflected in this diagram, in which we sustainably expand our capacity to supply both food and energywhile reducing our environmental footprint and providing pathways out of poverty.

    AFEX is a biobased technology that convertscellulose from crop residues into a sustainablesource of cattle feed and biofuels. Bulky andunwieldy crop residues and grasses are convertedinto pellets that are easily stored and transportedanywhere. The conversion takes place in a decentralized system of depots built where crops are grown, allowing the worlds rural poor to earn more for their families. To maximize global and societal impact, AFEX will be made available worldwide on an affordable, accessible basis.

    5

    A world-renowned scientist at Michigan StateUniversity discovered a way to liberate the sugars insidecrop residues and grasses, transforming them intoeither cattle feed or into a source of sustainable,renewable fuels. AFEX enters the global market at atime when urgent concerns about the worseningeffects of global warming and competition for fossilresources are compelling experts and concernedcitizens to examine ways to switch to renewable fuels.

    1 billion tons of AFEX pellets could produce enough renewable fuel to power 200 million cars each year.

    Renewable fuels from 1 billion tons of AFEX pellets could eliminate 680 million tons of fossil CO2 per year, equivalent to 9% of total U.S. emissions.

    ENERGY

    Its no secret better conservation practices would helpprevent the type of runoff that sparked Lake Eries algal blooms. Farmerswho are already squeezed financiallyneed more robust financial incentives to implement conservation best practices, like no-till farming, cover crops, and buffer strips. As a hallmark of its versatility as a multifaceted solution, AFEX provides farmers with an economic resource driver to support adoption of conservation best practices.

    Conservation practices such as no-till farming, cover crops, and buffer strips can reduce soil erosion and nutrient run-off by at least 50%.

    Implementing AFEX would provide a key market for crop residues and perennial grasses, thereby generating revenues needed to support the adoption of conservation practices.

    Through a globally accessible, market-oriented modeland a decentralized distribution design relying ondepots built in rural communities, AFEX offers the rare opportunity to make a significant impact in the lives of some of the neediest rural poor. India provides a telling case study in AFEXs potential impact.

    50 million rural families in India own only one or two dairy cattle. Low milk productivity of dairy cattle in developing nations could be improved by substituting AFEX pellets for the untreated crop residues these cattle are typically fed today.

    The annual profit per cow could easily triple as a result of AFEX, and this increased profit from a single cow is sufficient to lift a family of five above the poverty level.

    ENVIRONMENTAL FOOTPRINT RURAL POVERTY

  • 6Each AFEX DEPOT can directly create up to 30 new jobs

    Beef and Dairy Cattle

    Biorefineries: Fuels and Chemicals

    Farmers bring crop residues to local depot

    Depot upgrades the residues into dense pellets

    AFEX pellets can be either used locally or transported

    long distances

    6

    Each AFEX DEPOT can directly create up to 30 new jobs

    Beef and Dairy Cattle

    Biorefineries: Fuels and Chemicals

    Farmers bring crop residues to local depot

    Depot upgrades the residues into dense pellets

    AFEX pellets can be either used locally or transported

    long distances

    2 BILLION TONS OF GRAIN

    2 BILLION TONS OFUNDERUTILIZEDCROP RESIDUES

    2 BILLION TONS OF GRAIN

    2 BILLION TONS OF AFEX PELLETS

    FROM CROP RESIDUES

    AFEX UPGRADES EXISTING AGRICULTURAL PRODUCTION TO MEET RISING DEMAND FOR FOOD AND FUELS

    Current scenario shows corn, wheat, and rice production supporting 7 billion people today, 2 billion of whom are middle class (dark blue).

    A future 2050 scenario shows the grain complemented with AFEX pellets.AFEX offers significant potential to increase agricultural output to meet thegrowing food and fuel needs of 9 billion people 5 billion of whom will bemiddle class (dark blue).

  • 7Each AFEX DEPOT can directly create up to 30 new jobs

    Beef and Dairy Cattle

    Biorefineries: Fuels and Chemicals

    Farmers bring crop residues to local depot

    Depot upgrades the residues into dense pellets

    AFEX pellets can be either used locally or transported

    long distances

    RURAL COMMUNITY-BASED BIOMASS SUPPLY SYSTEM

    Implementing AFEX in a rural depotclose to where crops are growncreates new jobs, promotes rural economic development and environmental stewardship, and provides much-needed entrepreneurial opportunities for the rural poor. Multiplied across hundreds or thousands of communities worldwide, AFEX offers a compelling solution to the grand challenge.

    6

    Each AFEX DEPOT can directly create up to 30 new jobs

    Beef and Dairy Cattle

    Biorefineries: Fuels and Chemicals

    Farmers bring crop residues to local depot

    Depot upgrades the residues into dense pellets

    AFEX pellets can be either used locally or transported

    long distances

    2 BILLION TONS OF GRAIN

    2 BILLION TONS OFUNDERUTILIZEDCROP RESIDUES

    2 BILLION TONS OF GRAIN

    2 BILLION TONS OF AFEX PELLETS

    FROM CROP RESIDUES

    AFEX UPGRADES EXISTING AGRICULTURAL PRODUCTION TO MEET RISING DEMAND FOR FOOD AND FUELS

    Current scenario shows corn, wheat, and rice production supporting 7 billion people today, 2 billion of whom are middle class (dark blue).

    A future 2050 scenario shows the grain complemented with AFEX pellets.AFEX offers significant potential to increase agricultural output to meet thegrowing food and fuel needs of 9 billion people 5 billion of whom will bemiddle class (dark blue).

  • 8Progress to Date AFEX has been under extensive research and development at MSU for over twenty years. In 2010, MBI experts made a significant break-through in the equipment and process design, which led to the DOE funding $4.3 million to build a one-ton-per-day AFEX pilot plant at MBIs facility in Lansing, Michigan.

    The pilot plant has been successful and is currently being used to produce AFEX pellets for small-scale application trials. An initial evaluation in beef cattle was conducted at MSU in the fall of 2013, followed by an initial dairy cattle trial in November 2014both withpromising results.

    AFEX was recognized as the Transformational Pretreatment Technology of the Year, in 2014, by Biofuels Digest.

    E N A B L I N G G L O B A L I M P A C T : T H E P I O N E E R A F E X D E P O T

    Chandra Nielson and JoshVideto treat corn crop residue

    in MBIs pilot AFEX reactor.

    Whats Next: The Pioneer DepotThe next critical step is to design, build, andoperate a pioneer demonstration-scale (~10tons per day) AFEX depot. Such a depot will be essential to complete the technologydevelopment and support long-durationanimal feeding trials necessary to validate theproductivity and quality of the milk and meatproduced. In addition, the depot will beessential to develop a simple, robust designthat can be rapidly replicated in ruralcommunities worldwide. The pioneer depotwill also serve as an important training facilitysupporting the widespread dissemination of the technology.

    Achieving the Vision: Global Impact MBIs vision is to see the AFEX technology practiced around the world, so that maximum humanitarian and societal benefits can be realized. To achieve this vision, MBI aspires to offer unencumbered and affordable access to the technology on a worldwide basis. By supporting rapid technology transfer around the world, we expect to see a material positive impact on food, fuel, poverty, and the environment within the next twenty years.

  • WORLD MAP OF WHERE AFEX WILL BE FOUND GLOBALY

    Dark green represents countries with abundant crop-residue resources. Dashed lines illustrate potential for future spread of AFEX technology worldwide.

    AFEX TECHNOLOGY: POTENTIAL FOR GLOBAL IMPLEMENTATION

    9

  • 10

    MBI is committed to collaborating closely with international partners on designing and executing the AFEX project. In addition, we are committed to a milestone-based, stage-gated process in three phases. In Phase 1, we will generate critical data in a developing nation setting. In Phase 2, we will collaborate with a coalition of partners to design, build, and commission the pioneer AFEX depot in a devel-oping nation. In Phase 3, we will operate the depot to establish the robustness and viability of the technology and enable affordable, non-exclusive access for widespread adoption.

    PHASE 1: VIABILITY IN DEVELOPING NATIONS

    Depot: Assess prospect for biomass aggregation Select site for pioneer demonstration depot Select operating partners to support depot Complete front-end engineering design

    Technology/Applications: Use MBI pilot to generate AFEX pellets for

    applications testing Demonstrate utility of AFEX pellets in dairy

    and beef cattle trials Generate feeding trial data to support regulatory process Select key partners to support applications

    testing and adoption

    PHASE 2: DEMONSTRATION DEPOT

    Depot: Complete detailed engineering design Build and commission pioneer AFEX demonstration depot Develop and codify operating procedures Transfer technology and train depot personnel

    Technology/Applications: Continue use of MBI pilot plant to support

    technology development and applications trials

    Continue feeding trials to optimize AFEX pellet incorporation into cattle diets Initiate regulatory approval process with key

    partners

    B U I L D I N G T H E P I O N E E R D E P O T

  • 11

    PHASE 3: VALIDATION, TECHNOLOGY ACCESS, & SUPPORTING ADOPTION

    Depot: Demonstrate dependable and economically viable production of AFEX pellets Establish and demonstrate robust biomass supply chain Translate operating experience into a reliable and reproducible template

    Technology/Applications: Demonstrate utility and value proposition of AFEX pellets as cattle feed through

    large-scale trials Complete process required to obtain regulatory approval Establish acceptance of AFEX pellets in feed markets

    Adoption/Access: Offer depot design and operating technology on non-exclusive, low-cost basis Engage with early adopters to propagate AFEX depots Utilize pioneer depot to provide training and technical support for licensees Collaborate with philanthropic organizations, government agencies, and NGOs to

    promote widespread adoption

    ESTIMATED PROJECT HORIZON

    YEAR YEAR YEAR YEAR

    1 3 4 5

    YEAR

    2

    PHASE 124 MONTHS

    PHASE 224 MONTHS

    PHASE 312 MONTHS

  • 12

    Absent significant changes in how we produce our food and fuel, the planet will continue spiraling toward a precarious future. By addressing the four interconnected dimensions of food, energy, poverty, and the environment, AFEX can set us on a course toward a sustainable, prosperous future.

    MBI is both a mission-inspired 501(c)(3) and a market-driven biotech hub committed to enhancing quality of life around the world by collaboratively accelerating sustainable biobased technologies. Our vision is to maximize the positive humanitarian and societal benefits AFEX can have on the world.

    Without critical philanthropic support and key collaborative partnerships needed to complete the pioneer depot, we are unlikely to have the freedom to offer this revolutionary technology on an unencumbered, affordable basis.

    Partnering with our visionary team will have a direct effect on the comple-tion of the critical pioneer depot and create a lasting legacy through the technologys global reach.

    V I S I O N A R Y F O U N D A T I O N A L P A R T N E R S

  • M S U : A N E P I C E N T E R F O R B I O E C O N O M Y I N N O V A T I O N

    Michigan State University, founded in 1855, is the pioneer Land Grant institution, and one of the largest research universities in the world. MSU is in many ways the ideal location to support the development and eventual worldwide dissemination of a transformational technology such as AFEX. Some noteworthy programs on campus include:

    A leadership position in international engagement and outreach, comprising over 1,400 faculty and staff with over 280 partnerships in 70 countries, with the major focus on health, agriculture and food systems.

    Extensive agricultural extension networks and outreach within Michigan and the US Midwest through partnerships with major land-grant and private universities, including among others, University of Michigan, Ohio State University, University of Illinois, University of Wisconsin, University of Minnesota, Iowa State University, University of Nebraska, and Purdue University.

    The Great Lakes Bioenergy Research Center, a US Department of Energy-funded research initiative housed at MSU and University of Wisconsin that is dedicated to the research and development of sustainable biofuels from biomass resources. The Center includes over 400 faculty and staff.

    Extensive research expertise, faculties, and leadership in numerous fields including ecology, plant science, microbiology, soil sciences, agronomy, animal science and nutrition, food systems, sustainability, chemical and biosystems engineering, and agricultural economics.

    A B O U T M B I

    Rare among biotech hubs, MBI (Michigan Biotechnology Institute) is both a premier multidisciplinary center sought out by industry partners for unique derisking capabilities and a 501(c)(3) not-for-profit inspired by a mission to enhance quality of life by collaboratively accelerating the commercialization of sustainable biobased technologies.

    Consistent with that mission, we share selecttechnologiesthose that show the promise ofgame-changing sustainabilitywith the globalcommunity through low-cost, non-exclusivelicensing. Founded in 1981, Lansing, Michigan-based MBI is closely affiliated with MSU and isa wholly-owned subsidiary of the MSUFoundation.

    Technologies developed at MBI are recognizedand trusted worldwide. For example, togetherwith MSU and Cargill, MBI was responsible fordeveloping PLA, the polymer used worldwide tomake renewable and biodegradable containersand cutlery.

  • BOBBY BRINGI, CEO, MBI3815 TECHNOLOGY BOULEVARD LANSING, MI 48910-8596PHONE: 517.337.3181 EMAIL: [email protected]