allcells overview
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Your Reliable Source of Human Primary Cells
AllCells is a leading provider of hematology-based Products & Services to the world’s Life Science research community
• >800 healthy & diseased human primary cell products that enable advancement of scientific research
• Superior Supply-Chain and Efficient Work-Flow: Tissue Collection Clinic, lab facilities, plus network of diseased tissue providers
• Established 1998, headquartered in Emeryville, CA• Global Reach: direct USA sales force + WW distribution
via STEMCELL Technologies (ROW) and VERITAS (Japan)
• Small and Minority Owned Business certification
About AllCells, LLCAbout AllCells, LLC
AllCells primary cell Products & Services are used in areas of drug discovery & screening, stem cell research, regenerative medicine, cell therapy, cell-based assays, cell biology research, and other life science applications
Markets & ApplicationsMarkets & Applications
AllCells provides biologically relevant products that enable its customers to advance early stage drug discovery & preclinical development
Pharmaceutical Value ChainPharmaceutical Value Chain
Strong Customer BaseStrong Customer Base
LeukoLab LeukoLab • Wholly owned IRB-certified human tissue collection
clinic (Emeryville, CA)• largest volume bone marrow aspirates (up to 100 ml)• whole blood collections• r-GCSF mobilized and non-mobilized leukopheresis • large repository human donors
• Staffed with RNs, Physicians, Phlebotomists• Recruit human donors directly according to customer
criteria - active donor pool of >1,000 healthy volunteers
• Procedures comply with federal and California State Dept. of Health Regulations
Hematopoietic Stem cellsAllCells provides Hematopoietic Stem Cells isolated from various Human tissue:
• Bone Marrow• Normal Peripheral Blood• Mobilized Peripheral Blood• Cord Blood• Fetal Liver• CD34+ and CD133+ cells from all tissue types• Available fresh or frozen• Certificate of Analysis and FACScan Analysis Report
Products: Stem/ProgenitorProducts: Stem/Progenitor
Bone Marrow• Unprocessed Whole Bone Marrow• Mononuclear Cells• Stem/Progenitor Cells (CD34+ or CD133+)• Marrow Stromal Cells (similar to
Mesenchymal Stem Cells)• Endothelial Cells (CD105+)• Erythroid Cells (CD71+)• Myeloid Cells (CD33+)• Granulocytes (Neutrophils, Basophils, and
Eosinophils)
ProductsProducts
ProductsProductsNormal Peripheral Blood• Leuko Pak (contains average 1.6X1010 MNCs) • Processed Mononuclear Cells• Stem/Progenitor Cells (CD34+ or CD133+)• T Cells (Pan T, CD4+, and CD8+)• B Cells (CD19+)• Monocytes (CD14+)• NK Cells (CD56+)• Granulocytes (Neutrophils, Basophils,
Eosinophils)• Dendritic Cells (BDCA4+ Lymphoid Dendritic and
Monocyte derived Immature Dendritic)• Plasma, platelets, pure RBCs
ProductsProductsG-CSF Mobilized Peripheral Blood• Leuko Paks 1-Day and 2-Day collections• Processed Mononuclear Cells• Stem/Progenitor Cells (CD34+ or CD133+)• Early Erythroid Progenitor Cells (CD36+)• T Cells (Pan T, CD4+, and CD8+)• B Cells (CD19+)• Monocytes (CD14+)• NK Cells (CD56+)• Dendritic Cells (BDCA4+ Lymphoid Dendritic and
Monocyte derived Immature Dendritic)
ProductsProductsCord Blood• Processed Mononuclear Cells• Stem/Progenitor Cells (CD34+ or CD133+)• Early Erythroid Progenitor Cells (CD36+)• T Cells (Pan T, CD4+, CD8+, Naive T Cells
(CD4+/CD45RA+)• B Cells (CD19+)• Monocytes (CD14+)• NK Cells (CD56+)• Endothelial Cells (HUVEC)• Granulocytes (Neutrophils, Basophils, Eosinophils)• Plasma
Other ProductsOther Products• Fetal Liver Cells• Stem/Progenitor Cells (CD34+ or CD133+)• Early Erythroid Progenitor Cells (CD36+)
• RNA/cDNA (available for all cells types provided from AllCells)• Non-Human Primate Cells (Bone Marrow and Peripheral Blood)• Processed Mononuclear Cells• Granulocytes• Plasma• Bone Marrow Stem/Progenitor Cells (CD34+)
• Rat & Mouse Cells• Rat Pancreatic islets and other hematopoietic cells from Rat and Mouse
• Canine Endothelial Cells (CVEC)
• ALL/AML– Newly diagnosed– Relapsed/Refractory– Bone Marrow and Peripheral Blood– Purified cells
• CLL/CML– Newly diagnosed– Relapsed/Refractory– Bone Marrow and Peripheral Blood– Chronic phase/accelerated or Blast Crisis
(CML)
• Multiple Myeloma– Newly diagnosed– Relapsed/Refractory
• Non-Hodgkin’s Lymphoma– Burkitt’s Lymphoma (BL)– Diffuse Large B Cell Lymphoma
(DLBCL)– Follicular Lymphoma (FLL)– Mantle Cell Lymphoma (MCL)– Waldenstrom’s
Macroglobulinemia (WM)• Polycythemia Vera (PV)
AllCells has established Supply Agreements with an extensive network of oncology clinical sites
Comprehensive clinical reports are available for each sample and specific lot at www.allcells.com prior to purchase.
Oncology / Diseased ProductsOncology / Diseased Products
• Large Scale Processing & Cell Isolation:• healthy or diseased human tissue• molecular products (RNA/DNA, etc.) & lysates
• Drug Discovery Assay Services• colony formation assays e.g. CFU-GM, CFU-Mk• in vitro proliferation/inhibition assays (EC50)• mechanistic studies• toxicology
• Flow Cytometry Services• immunophenotyping, rare cell analysis, sorting
• Custom assays • cell cycle analysis• apoptosis, phospho protein analysis, CD34+ determination
under ISHAGE guidelines
Custom ServicesCustom Services
Industry Leader: Since 1998 AllCells has provided hematology-based products & services to the global Life Science industry
Market Applications: Drug discovery / toxicity, cell-based screening assays, stem cell research, cell therapy, regenerative medicine, Dx / biomarker discovery, gene expression
AllCells Competitive Advantage: Exceptional supply chain control - donor recruitment (profiles of interest), G-CSF mobilization, healthy & diseased tissue / cells, wholly owned IRB-certified clinic, fresh or frozen products, guaranteed cell viability, clinical reports, hematology expertise
Custom Services: Tissue sourcing, cell isolation, molecular products, cell-based assays, drug screening/preclinical development
Sales: Direct Sales USA + International Distributors
Bus. Dev: Interested in collaborations / strategic partnerships
SummarySummary
Ernie Desmarais Regional Account ManagerNortheast Region [email protected]: (617)997-2120 Office: (510)521-2600
Your Reliable Source of Human Primary Cells
Thank You !