alzheimer's: a woman's disease

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Post on 22-Jul-2016




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Alzheimer’s disease affects more women than men from a diagnosis standpoint. The Alzheimer’s Association’s 2011 Facts and Figures report shows that 3.4 million of the 5.4 million Americans living with Alzheimer’s are female. Women are also impacted by Alzheimer’s as the primary caregivers. Sixty percent of Alzheimer’s caregivers are women and of those women, 68 percent say they have emotional stress from caregiving. Learn about the many ways Alzheimer’s impacts women today and ways to cope with this increasing challenge. Amanda G. Smith, M.D., Medical Director, USF Health Byrd Alzheimer's Institute.


  • Alzheimers: A Womans Disease Amanda G. Smith, MD Medical Director, USF Health Byrd Alzheimers Institute

  • Disclosures

    Grant/Research support: Lilly, Merck, Eisai, Cognate Nutritionals, TauRX Contract payment to site (not investigator)

  • Dementia Dementia is the loss of cognitive function with

    aging due to degeneration of the brain Alzheimers is the most common form Definite diagnosis used to require autopsy Many mixed cases Some memory disorders are reversible and not

    truly dementia

  • Alzheimers Disease The most common cause of dementia Affects 1 in 40 Floridians, 1 in 66 Americans 1 in 3 seniors dies with some type of dementia Affects 10% of people over 65; 30-50% of

    people over 85 Over 5.4 million Americans presently By 2050, predicted to affect 16-20 million 6th leading cause of death in the USA Costs the nation $226 Billion annually By 2050 predicted to cost $1.1 Trillion

  • Women with Alzheimers

    Almost 2/3 of American seniors living with AD are women

    3.2 million women over 65 in the US 16 % of women over 71 have dementia vs 11%

    of men At age 65, a woman without AD has a 1 in 6

    chance of developing it, vs 1 in 11 in men Women in their 60s are 2x as likely to develop

    AD than breast cancer over the rest of their lives

  • 17.2



    Risk of Alzheimer's Risk of Breast Cancer

  • Why do women have higher risk?

    Women live longer Women are more likely to get AD if they carry

    the ApoE4 gene than men are Differences in cardiovascular risk Estrogen effects Educational attainment, esp. in oldest old

  • Women as Caregivers for AD

    63% of unpaid caregivers are women 60-70% of all caregivers are women Currently about 10 million women providing

    unpaid care Women account for greater hours and greater

    length of care than men

  • Women as Caregivers, continued

    Women are 2.5x more likely to provide 24hr care Women are 2.3 more likely to provide care for 5

    years or more Women are more likely to help with personal

    care Women are less likely to have additional support

    from family and friends

  • Caregiving: effects on health

    of female caregivers report physical stress compared to of male caregivers

    Nearly 2/3 of female caregivers report emotional stress

    1/3 of both men and women feel isolated but it is more commonly linked to depression in women

    of women express concern about their ability to maintain their health

  • 20



    Women Men

    Caregiving: Effects in the workplace

  • Caregiving: Effects in the workplace

    20% of women vs 3% of men have gone from full time to part time work due to caregiving

    19% of WWC had to quit working either to start caregiving or because it became too burdensome

    18% of WWC have taken a leave of absence from work

    10% have lost job benefits 17% report feeling penalized by their employers

  • What can you do?

    Physical exercise Mediterranean type diet Wear helmets and seatbelts Control cardiovascular risk factors Research hormone replacement with your doctor Reduce stress when possible Join the movement at Join the Brain Health Registry at