american psychiatric association. diagnostic and statistical manual of mental disorders, 4th ed....

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American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994. DSM-IV Diagnostic Criteria for PTSD Exposure to a traumatic event in which the person: experienced, witnessed, or was confronted by death or serious injury to self or others AND responded with intense fear, helplessness, or horror Symptoms appear in 3 symptom clusters: re-experiencing, avoidance/numbing, hyperarousal last for > 1 month cause clinically significant distress or impairment in functioning

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DSM-IV Diagnostic Criteria for PTSD Avoidance/Numbing Avoidance of stimuli and numbing of general responsiveness indicated by  3 of the following: –avoid thoughts, feelings, or conversations* –avoid activities, places, or people* –inability to recall part of trauma –  interest in activities –estrangement from others –restricted range of affect –sense of foreshortened future American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed

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Page 1: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994. DSM-IV Diagnostic Criteria for PTSD Exposure to

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994.

DSM-IV Diagnostic Criteria for PTSD• Exposure to a traumatic event in which the person:

– experienced, witnessed, or was confronted by death or serious injury to self or others AND

– responded with intense fear, helplessness, or horror• Symptoms

– appear in 3 symptom clusters: re-experiencing, avoidance/numbing, hyperarousal

– last for > 1 month– cause clinically significant distress or impairment in functioning

Page 2: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994. DSM-IV Diagnostic Criteria for PTSD Exposure to

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders,4th ed. 1994.

DSM-IV Diagnostic Criteria for PTSD Re-experiencing

• Persistent re-experiencing of 1 of the following:– recurrent distressing recollections of event– recurrent distressing dreams of event– acting or feeling event was recurring– psychological distress at cues resembling event– physiological reactivity to cues resembling event

Page 3: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994. DSM-IV Diagnostic Criteria for PTSD Exposure to

DSM-IV Diagnostic Criteria for PTSD Avoidance/Numbing

• Avoidance of stimuli and numbing of general responsiveness indicated by 3 of the following:– avoid thoughts, feelings, or conversations*– avoid activities, places, or people*– inability to recall part of trauma interest in activities– estrangement from others– restricted range of affect– sense of foreshortened future

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994.

Page 4: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994. DSM-IV Diagnostic Criteria for PTSD Exposure to

DSM-IV Diagnostic Criteria for PTSD Hyperarousal

• Persistent symptoms of increased arousal 2:– difficulty sleeping– irritability or outbursts of anger– difficulty concentrating– hypervigilance– exaggerated startle response

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994.

Page 5: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994. DSM-IV Diagnostic Criteria for PTSD Exposure to

Kessler R et al. J Clin Psychiatry. 2000;61(Suppl 5):4-14. Kessler R et al. Arch Gen Psychiatry. 1995;52:1048-1060.

Prevalence of Trauma and Probability of PTSD

Probability of PTSD

010203040506070

Witness Accident Threat w/Weapon

PhysicalAttack

Molestation Combat Rape

%

Prevalence of Trauma

0

10

20

30

40

%

MaleFemale

Witness Accident Threat w/Weapon

PhysicalAttack

Molestation Combat Rape

1

2

12

Page 6: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994. DSM-IV Diagnostic Criteria for PTSD Exposure to

Lifetime Prevalence of PTSD in the Community

5% LifetimePrevalence for Men

10.4% LifetimePrevalence for Women

Estimated LifetimePrevalence of PTSD = 7.8%

Kessler R et al. Arch Gen Psychiatry. 1995; 52:1048-1060.

Page 7: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994. DSM-IV Diagnostic Criteria for PTSD Exposure to

0

25

50

75

100

Vitality Social Function

PTSDMDDOCDUS Population

Impaired Quality of Life with PTSD

SF-36 = 36 item short form health surveyLower score = more impairmentMalik M et al. J Trauma Stress. 1999;12:387-393.

SF-36 Score

Page 8: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994. DSM-IV Diagnostic Criteria for PTSD Exposure to

1Kessler R et al. J Clin Psychiatry. 2000; 61 (Suppl 5): 4-12. 2Kessler R et al. Am J Psychiatry. 1999;156:115-123.

• Average work loss = 3.6 days/month1

• Annual productivity loss = $ 3 billion1

• Medical utilization: mean number of past year general medical visits2 – PTSD 5.3– Any anxiety disorder 4.4– Major depression 3.4

Economic Burden of PTSD

Page 9: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 1994. DSM-IV Diagnostic Criteria for PTSD Exposure to

Agoraphobia

0

10

20

30

40

50

60 MalesFemales

Com

orbi

dity

(%)

Psychiatric Comorbidity in PTSD

Major Depressive

Episode

GAD Panic Disorder

Social Anxiety Disorder

AlcoholAbuse/

Dependence

DrugAbuse/

Dependence

Kessler R et al. Arch Gen Psychiatry. 1995; 52:1048-1060.