Amoxicillin

Amoxicillin

Pronunciation

U.S. Brand Names

Generic Available

Canadian Brand Names

Synonyms

Pharmacological Index

Use

Pregnancy Risk Factor

Contraindications

Warnings/Precautions

Adverse Reactions

Overdosage/Toxicology

Drug Interactions

Stability

Mechanism of Action

Pharmacodynamics/Kinetics

Usual Dosage

Dietary Considerations

Monitoring Parameters

Test Interactions

Mental Health: Effects on Mental Status

Mental Health: Effects on Psychiatric Treatment

Dental Health: Local Anesthetic/Vasoconstrictor Precautions

Dental Health: Effects on Dental Treatment

Patient Information

Nursing Implications

Dosage Forms

References

Pronunciation

(a moks i SIL in)

U.S. Brand Names

Amoxil; Biomox; Trimox; Wymox

Generic Available

Yes

Canadian Brand Names

Apo-Amoxi; Novamoxin; Nu-Amoxi; Pro-Amox

Synonyms

Amoxicillin Trihydrate; Amoxycillin; p-Hydroxyampicillin

Pharmacological Index

Antibiotic, Penicillin

Use

Dental: Antibiotic for standard prophylactic regimen for dental patients who are at risk

Medical: Treatment of otitis media, sinusitis, and infections caused by susceptible organisms involving the respiratory tract, skin, and urinary tract; prophylaxis of bacterial endocarditis in patients undergoing surgical or dental procedures; approved in combination with clarithromycin and lansoprazole for eradication of H. pylori; in patients with active duodenal ulcer disease or a 1-year history of duodenal ulcer. The combined use of lansoprazole and amoxicillin is approved for patients unable to take clarithromycin.

Pregnancy Risk Factor

B

Contraindications

Hypersensitivity to amoxicillin, penicillin, or any component

Warnings/Precautions

In patients with renal impairment, doses and/or frequency of administration should be modified in response to the degree of renal impairment; a high percentage of patients with infectious mononucleosis have developed rash during therapy with amoxicillin; a low incidence of cross-allergy with other beta-lactams and cephalosporins exists

Adverse Reactions

1% to 10%:

Central nervous system: Fever

Dermatologic: Urticaria, rash

Miscellaneous: Allergic reactions (includes serum sickness, rash, angioedema, bronchospasm, hypotension, etc)