+ february 7, 2014 objective: to create a model of the cell membrane to explain the structure of the...
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+February 7, 2014
Objective:To create a model of the cell
membraneTo explain the structure of the cell
membrane
Journal: What does it mean to have a phobia of something? What is an example of a phobia?
+Key Terms
What do you think are the definitions of the following words?HydrophobicHydrophilic
+Key Terms Defined
Hydrophobic: Literally means fear of waterMolecules that are hydrophobic repel
water and try to stay away from water
Hydrophilic: Literally means water lovingMolecules that are hydrophilic are
attracted to water and tend to be found next to water
+Phospholipids
The structure of the phospholipid molecule generally consists of two hydrophobic tails and a hydrophilic head.
+Phosphate Head
Hydrophilic
Polar (has a charge)
Made of phosphate
+Two Fatty Acid Tails
Hydrophobic
Nonpolar (doesn’t have a charge)
Made of fatty acids
+Structure of the Cell Membrane
Phospholipids make up the cell membrane of cells.
+Phospholipid Cell Membrane Activity
Both inside and outside the cell contain water, so how do you think phospholipids are arranged to make a cell membrane?
Keep in mind that phospholipids contain hydrophilic heads and hydrophobic tails.
+Cell Membrane Structure
Phospholipids form a double layer called a Phospholipid Bilayer with the phosphate groups on the outside and the fatty acid tails in the middle
This happens because there is water inside and outside of the cell, so the water loving phosphate end is always by the water
+Structure Determines Function
The cell membrane structure helps it regulate what can and cannot pass through the phospholipid bilayer
+Selectively Permeable
The cell membrane is selectively permeable, meaning that not everything can go across it.Only certain things can get into the
cell and only certain things can leave the cell
+What can pass through the membrane?
This allows only small, nonpolar substances to pass directly through the phospholipid bilayer
All other substances are repelled by the nonpolar fatty acids, so they cannot go directly through the phospholipid bilayer
+Other Ways to Pass Through the Phospholipid Bilayer
The cell needs to let other things in and out of the cell so it uses membrane proteins to allow specific substances across the membrane at specific times
Membrane proteins can be found on top of or within the phospholipid bilayer
http://www.youtube.com/watch?v=LKN5sq5dtW4
+Types of Membrane Proteins
+Receptor Proteins
Found on the outside of your cells
Enable a cell to sense its surroundings by binding substances outside the cell Allows the cell to react
to its surroundings
+Cell-Surface Proteins
Similar to a nametag
Protein attached to a chain of carbohydrates attached to the cell membrane used to identify each type of cell
+Transport Proteins
Allows certain necessary substances that cannot pass through the cell membrane into and out of the cell
+Transport Proteins
Channel Proteins: Serve as a tunnel through the lipid bilayer that allow SPECIFIC ions, sugars, and amino acids to pass through the membraneEx: The channel for sodium ions does
not allow sugars to pass through
+Transport Proteins
Carrier Proteins: Only transport substances that fit within their binding site through the cell membraneCarrier protein binds to a specific substance
on one side of the cell membrane, changes shape and allows the substance out on the other side of the cell membrane
+Daily Activities
Day 1 – Egg Lab
Begin Cell Membrane Model
Homework: Cell Membrane Labeling Worksheet
+February 7, 2014 Objectives:
To differentiate between osmosis and diffusion
To describe how molecules can move down a concentration gradient
Journal: What do you think the following words
mean? Equal Concentration Diffuse
If the Monksville dam broke, what would happen to the water in the Monksville Reservoir?
+Cell Transport
+Passive Transport Vocabulary
Equilibrium: when there is an equal number of molecules on both sides of the cell membrane
Concentration: the amount of a particular substance in a given volume
Concentration Gradient: When there is a higher concentration of a substance on one side than the other
Diffusion: When a substance moves from an area of higher concentration to an area of lower concentration
+Types of Transport
Passive Transport: does not require energy to move substances across the cell membrane
Active Transport: requires energy to move substances across the cell membrane
+Passive Transport
When substances enter or leave the cell by diffusing across the cell membrane down their concentration gradient
The direction the substances move depends on the concentration gradient
+Types of Passive Transport
Simple Diffusion
Facilitated Diffusion
Osmosis
+Simple Diffusion
When small, nonpolar (uncharged) substances pass directly through the phospholipid bilayer from an area of higher concentration to an area of lower concentration
Ex: If there is more oxygen outside the cell than inside the cell, it will diffuse across the lipid bilayer and into the cell.
+
+Facilitated Diffusion
Substances that cannot pass directly through the membrane are helped to diffuse through the membrane using transport proteins
+Osmosis
Facilitated diffusion of water from an area of higher concentration to an area of lower concentration
Allows the cell to maintain water balance as their environment changes
+Water Channels
Since water is a polar substance, it does not directly diffuse across the cell membrane
So the cell has specific protein channels that only allow water to pass through called aquaporins
+Predicting Water Movement
The direction the water moves depends on the concentration of the cell’s environment
+Hypertonic
Water moves out of the cell
There is more solute outside the cell than inside the cell
The cell loses water and shrinks
+HypotonicWater moves in
There is more solute inside the cell than outside the cell
Cell gains water and expands
+Isotonic
There is the same concentration of water inside the cell and outside the cell
Equilibrium is reached
Cell stays the same size
+Daily Activities
Egg Lab Day 2 – Place eggs in various solutions
Finish Cell Membrane Model
+February 11, 2014
Objectives:To differentiate active transport from active
transportTo describe how active transport moves
molecules
Journal:How is active different than passive?
+Active Transport
Transport of substances against their concentration gradients
Requires energy usually in the form of ATP
+Use of Carrier Proteins as Pumps
Carrier proteins require energy to pump substances across their concentration gradient
+Sodium-Potassium Pump
Sodium ions inside the cell bind to the carrier protein which changes shape and releases sodium ions outside the cell membrane
As a result a phosphate group is released from the pump, returning the channel protein to its original shape, and releasing potassium ions inside the cell
For every three sodium ions pumped out, two potassium ions are brought inside
This prevents sodium from building up inside the cell, which would cause the cell to burst due to osmosis bringing in too much water
+Vesicles
Large substances are too big to cross the membrane in channel proteins so they use vesicles
Vesicle membranes are lipid bilayer, so they can bud off from the cell membrane or fuse with it to move large substances in or out of the cell
+Endocytosis
The movement of large substances into a cell using a vesicle
The cell membrane forms a pouch around the substance that closes and then pinches off inside the cellPinocytosis: also known as cellular
drinking, engulfing liquid particlesPhagocytosis: engulfing solid particles
+Exocytosis
The movement of large substances out of a cell using a vesicle
Vesicles inside the cell fuse with the cell membrane and are released outside the cell
Used to transport proteins modified by the Golgi apparatus, excrete wastes, or remove bacteria
+Daily Activities
Day 3 – Finish Egg Lab
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